ATE460426T1 - Cyclopeptidderivate mit anti-integrin-wirkung - Google Patents

Cyclopeptidderivate mit anti-integrin-wirkung

Info

Publication number: ATE460426T1
Authority: AT; Austria
Prior art keywords: cyclopeptide derivatives; integrin; effect; integrin effect; cyclopeptide
Prior art date: 2004-05-13

Application number

AT05742999T

Other languages

English (en)

Inventor

Pozzo Alma Dal

Sergio Penco

Giuseppe Giannini

Maria Tinti

Claudio Pisano

Loredana Vesci

Ming Hong Ni

Original Assignee

Sigma Tau Ind Farmaceuti

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2004-05-13

Filing date

2005-05-04

Publication date

2010-03-15

2005-05-04 Application filed by Sigma Tau Ind Farmaceuti filed Critical Sigma Tau Ind Farmaceuti

2010-03-15 Application granted granted Critical

2010-03-15 Publication of ATE460426T1 publication Critical patent/ATE460426T1/de

Links

102000001189 Cyclic Peptides Human genes 0.000 title 1
108010069514 Cyclic Peptides Proteins 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/64—Cyclic peptides containing only normal peptide links
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/12—Cyclic peptides with only normal peptide bonds in the ring
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/12—Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/20—Antivirals for DNA viruses
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/04—Antineoplastic agents specific for metastasis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
Medicinal Chemistry (AREA)
General Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Molecular Biology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Genetics & Genomics (AREA)
Biophysics (AREA)
Biochemistry (AREA)
Physical Education & Sports Medicine (AREA)
Rheumatology (AREA)
Orthopedic Medicine & Surgery (AREA)
Oncology (AREA)
Virology (AREA)
Immunology (AREA)
Communicable Diseases (AREA)
Heart & Thoracic Surgery (AREA)
Cardiology (AREA)
Tropical Medicine & Parasitology (AREA)
Urology & Nephrology (AREA)
Biotechnology (AREA)
Ophthalmology & Optometry (AREA)
Pain & Pain Management (AREA)
Gastroenterology & Hepatology (AREA)
Epidemiology (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Peptides Or Proteins (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

AT05742999T 2004-05-13 2005-05-04 Cyclopeptidderivate mit anti-integrin-wirkung ATE460426T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
IT000239A ITRM20040239A1 (it)	2004-05-13	2004-05-13	Derivati ciclopeptidici ad attivita' antintegrine.
PCT/IT2005/000262 WO2005111064A1 (en)	2004-05-13	2005-05-04	Cyclopeptide derivatives with anti-integrin activity

Publications (1)

Publication Number	Publication Date
ATE460426T1 true ATE460426T1 (de)	2010-03-15

Family

ID=34968013

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT05742999T ATE460426T1 (de)	2004-05-13	2005-05-04	Cyclopeptidderivate mit anti-integrin-wirkung

Country Status (23)

Country	Link
US (1)	US20070178045A1 (de)
EP (1)	EP1751176B1 (de)
JP (1)	JP2008500971A (de)
KR (1)	KR20070012524A (de)
CN (1)	CN1953990A (de)
AR (1)	AR048957A1 (de)
AT (1)	ATE460426T1 (de)
AU (1)	AU2005243418A1 (de)
BR (1)	BRPI0510985A (de)
CA (1)	CA2562576A1 (de)
CY (1)	CY1110039T1 (de)
DE (1)	DE602005019876D1 (de)
DK (1)	DK1751176T3 (de)
ES (1)	ES2340862T3 (de)
HR (1)	HRP20100301T1 (de)
IT (1)	ITRM20040239A1 (de)
MX (1)	MXPA06012887A (de)
PL (1)	PL1751176T3 (de)
PT (1)	PT1751176E (de)
RS (1)	RS51300B (de)
SI (1)	SI1751176T1 (de)
TW (1)	TW200606178A (de)
WO (1)	WO2005111064A1 (de)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
ES2436109T3 (es) *	2006-02-09	2013-12-27	Belrose Pharma Inc.	Conjugados poliméricos de múltiples brazos de 7-etil-10-hidroxicamptotecina para el tratamiento del cáncer de mama, del cáncer colorrectal, del cáncer de páncreas, de ovario y de pulmón
EP1961759A1 (de) *	2007-02-21	2008-08-27	Universita'degli Studi Di Milano	Auf Integrin gerichtete Cyclopeptidliganden, deren Herstellung und Verwendung
TWI474819B (zh)	2012-05-15	2015-03-01	國立成功大學	調控物及含有該調控物之醫藥組合物
JP2016515120A (ja) *	2013-03-15	2016-05-26	バイオジェン・エムエイ・インコーポレイテッドＢｉｏｇｅｎＭＡＩｎｃ．	抗アルファｖベータ５抗体を用いた急性腎損傷の治療及び予防
CN103588863B (zh) *	2013-11-15	2016-08-17	苏州强耀生物科技有限公司	Rgd环肽合成制备工艺
WO2022183360A1 (en) *	2021-03-02	2022-09-09	Tsao Yeou Ping	Short synthetic peptide and their uses for treating dry eye disease

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE4310643A1 (de) *	1993-04-01	1994-10-06	Merck Patent Gmbh	Cyclische Adhäsionsinhibitoren
US5449761A (en) *	1993-09-28	1995-09-12	Cytogen Corporation	Metal-binding targeted polypeptide constructs
US6027711A (en) *	1995-06-07	2000-02-22	Rhomed Incorporated	Structurally determined metallo-constructs and applications
DE19725368A1 (de) *	1997-06-16	1998-12-17	Merck Patent Gmbh	Cyclische Adhäsionsinhibitoren und deren Verwendung für bildgebende Verfahren
ITRM20040240A1 (it) *	2004-05-13	2004-08-13	Ist Naz Stud Cura Dei Tumori	Camptotecine coniugate in posizione 7 con antagonisti delle integrine.
ITRM20040242A1 (it) *	2004-05-13	2004-08-13	Ist Naz Stud Cura Dei Tumori	"7-t-butossiimminometilcamptotecina coniugata in posizione 20 con antagonisti delle integrine.

2004
- 2004-05-13 IT IT000239A patent/ITRM20040239A1/it unknown
2005
- 2005-05-04 SI SI200530986T patent/SI1751176T1/sl unknown
- 2005-05-04 WO PCT/IT2005/000262 patent/WO2005111064A1/en not_active Ceased
- 2005-05-04 DE DE602005019876T patent/DE602005019876D1/de not_active Expired - Lifetime
- 2005-05-04 PL PL05742999T patent/PL1751176T3/pl unknown
- 2005-05-04 CN CNA2005800152380A patent/CN1953990A/zh active Pending
- 2005-05-04 DK DK05742999.5T patent/DK1751176T3/da active
- 2005-05-04 MX MXPA06012887A patent/MXPA06012887A/es active IP Right Grant
- 2005-05-04 CA CA002562576A patent/CA2562576A1/en not_active Abandoned
- 2005-05-04 TW TW094114404A patent/TW200606178A/zh unknown
- 2005-05-04 AU AU2005243418A patent/AU2005243418A1/en not_active Abandoned
- 2005-05-04 KR KR1020067025228A patent/KR20070012524A/ko not_active Ceased
- 2005-05-04 PT PT05742999T patent/PT1751176E/pt unknown
- 2005-05-04 HR HR20100301T patent/HRP20100301T1/hr unknown
- 2005-05-04 JP JP2007512736A patent/JP2008500971A/ja not_active Withdrawn
- 2005-05-04 RS RSP-2010/0231A patent/RS51300B/sr unknown
- 2005-05-04 BR BRPI0510985-0A patent/BRPI0510985A/pt not_active IP Right Cessation
- 2005-05-04 AT AT05742999T patent/ATE460426T1/de not_active IP Right Cessation
- 2005-05-04 US US11/596,190 patent/US20070178045A1/en not_active Abandoned
- 2005-05-04 EP EP05742999A patent/EP1751176B1/de not_active Expired - Lifetime
- 2005-05-04 ES ES05742999T patent/ES2340862T3/es not_active Expired - Lifetime
- 2005-05-13 AR ARP050101955A patent/AR048957A1/es unknown
2010
- 2010-05-19 CY CY20101100440T patent/CY1110039T1/el unknown

Also Published As

Publication number	Publication date
RS51300B (sr)	2010-12-31
HRP20100301T1 (hr)	2010-06-30
ES2340862T3 (es)	2010-06-10
WO2005111064A8 (en)	2006-02-09
PT1751176E (pt)	2010-05-12
JP2008500971A (ja)	2008-01-17
SI1751176T1 (sl)	2010-06-30
PL1751176T3 (pl)	2010-08-31
KR20070012524A (ko)	2007-01-25
EP1751176A1 (de)	2007-02-14
CY1110039T1 (el)	2012-05-23
TW200606178A (en)	2006-02-16
AR048957A1 (es)	2006-06-14
CN1953990A (zh)	2007-04-25
US20070178045A1 (en)	2007-08-02
EP1751176B1 (de)	2010-03-10
DK1751176T3 (da)	2010-06-14
ITRM20040239A1 (it)	2004-08-13
MXPA06012887A (es)	2007-02-15
BRPI0510985A (pt)	2007-12-04
CA2562576A1 (en)	2005-11-24
DE602005019876D1 (de)	2010-04-22
WO2005111064A1 (en)	2005-11-24
AU2005243418A1 (en)	2005-11-24

Legal Events

Date

Code

Title

Description

2010-09-15

UEP

Publication of translation of european patent specification

Ref document number: 1751176

Country of ref document: EP

2012-02-15

REN

Ceased due to non-payment of the annual fee

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