ATE46172T1 - Verbindungen, diese enthaltende pharmazeutische zusammensetzungen und verfahren zur herstellung. - Google Patents

Verbindungen, diese enthaltende pharmazeutische zusammensetzungen und verfahren zur herstellung.

Info

Publication number
ATE46172T1
ATE46172T1 AT83111894T AT83111894T ATE46172T1 AT E46172 T1 ATE46172 T1 AT E46172T1 AT 83111894 T AT83111894 T AT 83111894T AT 83111894 T AT83111894 T AT 83111894T AT E46172 T1 ATE46172 T1 AT E46172T1
Authority
AT
Austria
Prior art keywords
compounds
manufacture
pharmaceutical compositions
compositions containing
substituents
Prior art date
Application number
AT83111894T
Other languages
English (en)
Inventor
Huang Fu-Chih
Howard Jones
Chan Wan-Kit
Original Assignee
Rorer Int Overseas
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Rorer Int Overseas filed Critical Rorer Int Overseas
Application granted granted Critical
Publication of ATE46172T1 publication Critical patent/ATE46172T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C241/00Preparation of compounds containing chains of nitrogen atoms singly-bound to each other, e.g. hydrazines, triazanes
    • C07C241/02Preparation of hydrazines
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/02Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
    • C07K5/022Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -X-C(=O)-(C)n-N-C-C(=O)-Y-; X and Y being heteroatoms; n being 1 or 2
    • C07K5/0222Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -X-C(=O)-(C)n-N-C-C(=O)-Y-; X and Y being heteroatoms; n being 1 or 2 with the first amino acid being heterocyclic, e.g. Pro, Trp
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/13Amines
    • A61K31/15Oximes (>C=N—O—); Hydrazines (>N—N<); Hydrazones (>N—N=) ; Imines (C—N=C)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C243/00Compounds containing chains of nitrogen atoms singly-bound to each other, e.g. hydrazines, triazanes
    • C07C243/24Hydrazines having nitrogen atoms of hydrazine groups acylated by carboxylic acids
    • C07C243/26Hydrazines having nitrogen atoms of hydrazine groups acylated by carboxylic acids with acylating carboxyl groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C243/34Hydrazines having nitrogen atoms of hydrazine groups acylated by carboxylic acids with acylating carboxyl groups bound to hydrogen atoms or to acyclic carbon atoms to carbon atoms of a carbon skeleton further substituted by nitrogen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/02Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
    • C07K5/022Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -X-C(=O)-(C)n-N-C-C(=O)-Y-; X and Y being heteroatoms; n being 1 or 2
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/80Antihypertensive peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Steroid Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Earth Drilling (AREA)
  • Magnetic Resonance Imaging Apparatus (AREA)
AT83111894T 1982-11-29 1983-11-28 Verbindungen, diese enthaltende pharmazeutische zusammensetzungen und verfahren zur herstellung. ATE46172T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US06/445,117 US4482544A (en) 1982-11-29 1982-11-29 Compounds for treating hypertension
EP83111894A EP0112511B1 (de) 1982-11-29 1983-11-28 Verbindungen, diese enthaltende pharmazeutische Zusammensetzungen und Verfahren zur Herstellung

Publications (1)

Publication Number Publication Date
ATE46172T1 true ATE46172T1 (de) 1989-09-15

Family

ID=23767670

Family Applications (1)

Application Number Title Priority Date Filing Date
AT83111894T ATE46172T1 (de) 1982-11-29 1983-11-28 Verbindungen, diese enthaltende pharmazeutische zusammensetzungen und verfahren zur herstellung.

Country Status (15)

Country Link
US (1) US4482544A (de)
EP (1) EP0112511B1 (de)
JP (1) JPS59108752A (de)
KR (1) KR840007563A (de)
AT (1) ATE46172T1 (de)
AU (1) AU2176183A (de)
CA (1) CA1249394A (de)
DE (1) DE3380517D1 (de)
ES (1) ES527854A0 (de)
FI (1) FI834362A7 (de)
IL (1) IL70342A0 (de)
NO (1) NO834387L (de)
NZ (1) NZ206433A (de)
PH (1) PH19870A (de)
ZA (1) ZA838855B (de)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4596791A (en) * 1983-03-16 1986-06-24 Usv Pharmaceutical Corp. Compounds for treating hypertension
US4666906A (en) * 1983-03-16 1987-05-19 Usv Pharmaceutical Corporation Compounds for treating hypertension
ZA843899B (en) * 1983-05-23 1984-12-24 Usv Pharma Corp Compounds for treating hypertension
EP0137746A3 (de) * 1983-09-22 1986-01-08 FISONS plc Stickstoffhaltige substituierte Inhibitoren vom Angiotensin-Umwandlungs-Enzym
DE3569368D1 (en) * 1984-11-30 1989-05-18 Fisons Plc Angiotensin converting enzyme inhibitors and their production and use as pharmaceuticals
SE8803847A0 (sv) * 1988-10-27 1990-04-28 Kabigen Ab Neuromodulerande peptid
EP0845438B1 (de) * 1996-11-28 2001-09-19 Kurita Water Industries Ltd. Sauerstoffentfernungsmittel als Verbindung für die Behandlung von Kesselsteinspeisewasser

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL58849A (en) * 1978-12-11 1983-03-31 Merck & Co Inc Carboxyalkyl dipeptides and derivatives thereof,their preparation and pharmaceutical compositions containing them
AU556932B2 (en) * 1981-03-30 1986-11-27 Usv Pharmaceutical Corp. Dipetide with heterocyclic groiup
US4820729A (en) * 1981-03-30 1989-04-11 Rorer Pharmaceutical Corporation N-substituted-amido-amino acids
DK156484A (da) * 1983-03-16 1984-09-17 Usv Pharma Corp Aminosyrederivater

Also Published As

Publication number Publication date
JPS59108752A (ja) 1984-06-23
KR840007563A (ko) 1984-12-08
NZ206433A (en) 1986-07-11
IL70342A0 (en) 1984-02-29
ES8507472A1 (es) 1985-10-01
DE3380517D1 (en) 1989-10-12
CA1249394A (en) 1989-01-24
NO834387L (no) 1984-05-30
AU2176183A (en) 1984-06-07
EP0112511B1 (de) 1989-09-06
ES527854A0 (es) 1985-10-01
FI834362L (fi) 1984-05-30
US4482544A (en) 1984-11-13
FI834362A0 (fi) 1983-11-29
FI834362A7 (fi) 1984-05-30
EP0112511A3 (en) 1985-11-13
EP0112511A2 (de) 1984-07-04
PH19870A (en) 1986-08-13
ZA838855B (en) 1984-07-25

Similar Documents

Publication Publication Date Title
FI921030A0 (fi) Cykliska ureaderivat, dessa foereningar innehaollande laekemedel och foerfarande foer deras framstaellning.
ES485188A1 (es) Procedimiento para preparar 1-piperazina-carboxamidas y car-botiamidas
DE69100079D1 (de) Naphthalin-derivate, verfahren zu ihrer herstellung und sie enthaltende pharmazeutische zusammensetzungen.
PT76336A (de) Cephalosporinderivate und verfahren zu ihrer herstellung
SE7614258L (sv) Forfarande for framstellning av kinazoloderivat
MX9202996A (es) Diazabiciclo-(3-3-1)nonanos.
DE3581566D1 (de) Oxindol-derivate, verfahren zu ihrer herstellung, diese verbindungen enthaltende arzneimittel und zwischenprodukte.
ATE224T1 (de) 1,2-dihydro-chinolin-2-on-derivate, verfahren zu deren herstellung sowie diese verbindungen enthaltende arzneimittel.
ATE45153T1 (de) Benzisoselenazolthione, verfahren zu ihrer herstellung und diese verbindungen enthaltende pharmazeutische produkte.
ES8207169A1 (es) Un procedimiento para la preparacion de nuevos derivados de piperazinilquinazolina y de homopiperazinilquinazolina hi- pertensora con acticidad.
DE3483204D1 (de) 4h-3,1-benzoxazin-4-ones und verwandte verbindungen, sie enthaltende pharmazeutische zusammensetzungen und verfahren ihrer herstellung.
DK148183A (da) Fremgangsmaade til fremstilling af imidazolylphenyl-tetrahydropyridaziner
UA50711C2 (uk) Антрациклінові похідні, їх застосування при лікуванні амілоїдозу та фармацевтична композиція
ATE27456T1 (de) Kristallinische aenderungen, verfahren zu deren herstellung und diese enthaltende pharmazeutische praeparate.
ATE41772T1 (de) Polymethoxybenzyl-piperazin-derivate, verfahren zu ihrer herstellung und diese derivate enthaltende pharmazeutische zusammensetzungen.
ATE46172T1 (de) Verbindungen, diese enthaltende pharmazeutische zusammensetzungen und verfahren zur herstellung.
SE7707689L (sv) 2-brom-6-fluor-n-2-imidazolidinylidenbensamin dess syraadditionssalter, lekemedel innehallande dessa och forfarande for framstellning derav
ATE30426T1 (de) Peneme, sie enthaltende pharmazeutische zusammensetzungen und verfahren zu ihrer herstellung.
DE69132580D1 (de) 7-Acyl-3-(substituierte carbamoyloxy) Cephem Verbindungen, Verfahren zu ihrer Herstellung und Anwendung
AU6814387A (en) Phenylacetonitriles which are substituted by basic groups, their preparation and drugs containing these substances
ATE13423T1 (de) Guanidinderivate und diese enthaltende pharmazeutische zusammensetzungen.
ATE16278T1 (de) Hydroxybenzylamino-aryl verbindungen, verfahren zur deren herstellung und diese verbindungen enthaltende pharmazeutische zusammensetzungen.
DE3887102D1 (de) Substituierte Derivate von 20,21-Dinoreburnamenin, Verfahren zur Herstellung und so hergestellte Zwischenprodukte, ihre Verwendung als Arzneimittel und diese enthaltende pharmazeutische Zusammenstellungen.
ATE67186T1 (de) 3-methylphthalimide.
SE8206128D0 (sv) Farmaceutisk komposition for behandling av njurstenar framkallade genom infektion

Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties