ATE462689T1 - Vitamin-d-derivate mit substituenten an der 2- alpha-position - Google Patents

Vitamin-d-derivate mit substituenten an der 2- alpha-position

Info

Publication number
ATE462689T1
ATE462689T1 AT00955023T AT00955023T ATE462689T1 AT E462689 T1 ATE462689 T1 AT E462689T1 AT 00955023 T AT00955023 T AT 00955023T AT 00955023 T AT00955023 T AT 00955023T AT E462689 T1 ATE462689 T1 AT E462689T1
Authority
AT
Austria
Prior art keywords
group
vitamin
substituents
saturated aliphatic
derivatives
Prior art date
Application number
AT00955023T
Other languages
English (en)
Inventor
Hiroaki Takayama
Toshie Fujishima
Yoshitomo Suhara
Ken-Ichi Nihei
Katsuhiro Konno
Original Assignee
Hiroaki Takayama
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hiroaki Takayama filed Critical Hiroaki Takayama
Application granted granted Critical
Publication of ATE462689T1 publication Critical patent/ATE462689T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C401/00—Irradiation products of cholesterol or its derivatives; Vitamin D derivatives, 9,10-seco cyclopenta[a]phenanthrene or analogues obtained by chemical preparation without irradiation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/02—Nutrients, e.g. vitamins, minerals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/12—Drugs for disorders of the metabolism for electrolyte homeostasis
    • A61P3/14—Drugs for disorders of the metabolism for electrolyte homeostasis for calcium homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Endocrinology (AREA)
  • Rheumatology (AREA)
  • Nutrition Science (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
AT00955023T 1999-08-27 2000-08-25 Vitamin-d-derivate mit substituenten an der 2- alpha-position ATE462689T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP24165099 1999-08-27
PCT/JP2000/005743 WO2001016099A1 (fr) 1999-08-27 2000-08-25 DÉRIVÉS DE VITAMINE D AYANT DES SUBSTITUANTS À LA POSITION 2$g(a)

Publications (1)

Publication Number Publication Date
ATE462689T1 true ATE462689T1 (de) 2010-04-15

Family

ID=17077481

Family Applications (1)

Application Number Title Priority Date Filing Date
AT00955023T ATE462689T1 (de) 1999-08-27 2000-08-25 Vitamin-d-derivate mit substituenten an der 2- alpha-position

Country Status (7)

Country Link
US (1) US20050113349A1 (de)
EP (1) EP1219599B1 (de)
AT (1) ATE462689T1 (de)
AU (1) AU6730600A (de)
DE (1) DE60044090D1 (de)
DK (1) DK1219599T3 (de)
WO (1) WO2001016099A1 (de)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2003070697A1 (fr) * 2002-02-25 2003-08-28 Chugai Seiyaku Kabushiki Kaisha Procede de dosage de l'activite de liaison a un recepteur de la vitamine d3, utilisant la polarisation de fluorescence
JP2011241170A (ja) * 2010-05-18 2011-12-01 Mercian Corp ビタミンｄ誘導体およびその製造方法
GB202016614D0 (en) 2020-10-20 2020-12-02 King S College London Compounds

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1332841C (en) * 1984-11-27 1994-11-01 Noboru Kubodera Vitamin d derivatives and process for producing the same
US5378695A (en) * 1989-02-23 1995-01-03 Leo Pharmaceutical Products Ltd. A/S (Lovens Kemiske Fabrik Produktionsaktieselskab) Vitamin D analogues
US5401732A (en) * 1989-02-23 1995-03-28 Leo Pharmaceutical Products Ltd. A/S Kemiske Fabrik Produkionsaktiese Skab Vitamin D analogues
JP3213092B2 (ja) * 1991-11-01 2001-09-25 中外製薬株式会社 ２β位に置換基を有するビタミンＤ誘導体
JP3493037B2 (ja) * 1991-12-18 2004-02-03 中外製薬株式会社 ２２−オキサコレカルシフェロール誘導体とその製造方法
EP0619306B1 (de) * 1993-04-05 1996-09-11 Wisconsin Alumni Research Foundation 19-Nor-vitamin-D3-Verbindung mit einem Substituent an die 2. Stelle
ATE195513T1 (de) * 1994-04-11 2000-09-15 Chugai Pharmaceutical Co Ltd 22-thiavitamin-d3-derivate
WO1996001811A1 (en) * 1994-07-11 1996-01-25 The Johns-Hopkins University 2-substituted 1,25-dihydroxyvitamin d3 derivatives
WO1996022973A1 (fr) * 1995-01-23 1996-08-01 Chugai Seiyaku Kabushiki Kaisha Derives de vitamine d3 de 2-substitution
US5877168A (en) * 1995-02-10 1999-03-02 Chugai Seiyaku Kabushiki Kaisha Vitamin D derivative with substituent at the 2β-position
DE69606680T2 (de) * 1995-10-30 2000-08-17 F. Hoffmann-La Roche Ag, Basel 1-Alpha, 26-dihydroxy-D-homo-vitamin D3
US5716946A (en) * 1996-02-13 1998-02-10 Wisconsin Alumni Research Foundation Multiple sclerosis treatment
US5891865A (en) * 1996-10-04 1999-04-06 Wisconsin Alumni Research Foundation Treatment of arthritic disease induced by infectious agents
JP2002510304A (ja) * 1997-06-06 2002-04-02 ウイスコンシン アラムナイ リサーチ フオンデーシヨン 移植体拒絶反応を防ぐためのビタミンｄ化合物の使用
US5939406A (en) * 1997-07-21 1999-08-17 Wisconsin Alumni Research Foundation 18-substituted-19-nor-vitamin D compounds
WO2000066548A1 (en) * 1999-04-28 2000-11-09 Chugai Seiyaku Kabushiki Kaisha 2-alkylated vitamin d derivatives
CA2410880C (en) * 2000-05-31 2009-03-03 Wisconsin Alumni Research Foundation 2-ethyl and 2-ethylidene-19-nor-vitamin d compounds

Also Published As

Publication number Publication date
DK1219599T3 (da) 2010-05-25
WO2001016099A1 (fr) 2001-03-08
EP1219599A4 (de) 2002-09-11
AU6730600A (en) 2001-03-26
EP1219599A1 (de) 2002-07-03
EP1219599B1 (de) 2010-03-31
US20050113349A1 (en) 2005-05-26
DE60044090D1 (de) 2010-05-12

Similar Documents

Publication Publication Date Title
ATE282630T1 (de) Dolastatin-derivate
DE69628276D1 (de) Zubereitung von xanthinderivaten als feste dispersion
DE69628804D1 (de) Substitutierte heterozyclische Derivate als CRF Antagonisten
DK1026147T3 (da) Forbindelser, der er anvendelige som mellemprodukter i fremstillingen af piperidinderivater
NO983970D0 (no) Tricykliske forbindelser, deres fremstilling og anvendelse
ATE417038T1 (de) Phenylpyridincarbonyl piperazinderivate
CY1107010T1 (el) Παραγωγο βενζοϋλπυριδινης ´η αλας αυτης, μυκητοκτονο που περιεχει αυτο σαν δραστικο συστατικο, μεθοδος παρασκευης αυτου και ενδιαμεσο για παρασκευη αυτου
ATE88714T1 (de) 2'-desoxy-5-fluoruridinderivate.
DK0775702T3 (da) Hidtil ukendte quinolon- eller naphthylidoncarboxylsyrederivater eller salt deraf
ATE278661T1 (de) Anthranilsäurederivate
AU5504694A (en) Substituted amic acid derivatives
ES2126075T3 (es) Derivados biciclicos nitrogenados como inhibidores de la propil-endopeptidasa.
DE69931051D1 (de) Neue vinylbenzolderivate
DE69617909D1 (de) 2-substituierte vitamin-d3-derivate
ATE360612T1 (de) In 4-stellung substituierte piperidinderivate
DE60044090D1 (de) Vitamin-d-derivate mit substituenten an der 2-alpha-position
DK1050530T3 (da) 1-aza-2-alkyl-6-aryl-cycloalkaner til forbedring af hukommelsen
ATE194621T1 (de) Pyrazolothiazolopyrimidin-derivate
ATE420855T1 (de) 2-substituierte vitamin-d-derivate

Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties