ATE360612T1 - In 4-stellung substituierte piperidinderivate - Google Patents
In 4-stellung substituierte piperidinderivateInfo
- Publication number
- ATE360612T1 ATE360612T1 AT00956885T AT00956885T ATE360612T1 AT E360612 T1 ATE360612 T1 AT E360612T1 AT 00956885 T AT00956885 T AT 00956885T AT 00956885 T AT00956885 T AT 00956885T AT E360612 T1 ATE360612 T1 AT E360612T1
- Authority
- AT
- Austria
- Prior art keywords
- piperidine derivatives
- derivatives substituted
- provides
- hydrates
- chem
- Prior art date
Links
- NQRYJNQNLNOLGT-UHFFFAOYSA-N Piperidine Chemical group C1CCNCC1 NQRYJNQNLNOLGT-UHFFFAOYSA-N 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 2
- 102000012440 Acetylcholinesterase Human genes 0.000 abstract 1
- 108010022752 Acetylcholinesterase Proteins 0.000 abstract 1
- 229940022698 acetylcholinesterase Drugs 0.000 abstract 1
- 150000004677 hydrates Chemical class 0.000 abstract 1
- 230000002401 inhibitory effect Effects 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
- C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D211/30—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by doubly bound oxygen or sulfur atoms or by two oxygen or sulfur atoms singly bound to the same carbon atom
- C07D211/32—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by doubly bound oxygen or sulfur atoms or by two oxygen or sulfur atoms singly bound to the same carbon atom by oxygen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Psychology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
- Plural Heterocyclic Compounds (AREA)
- Steroid Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP24711599 | 1999-09-01 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE360612T1 true ATE360612T1 (de) | 2007-05-15 |
Family
ID=17158668
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT00956885T ATE360612T1 (de) | 1999-09-01 | 2000-09-01 | In 4-stellung substituierte piperidinderivate |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US7091218B1 (de) |
| EP (1) | EP1209151B1 (de) |
| AT (1) | ATE360612T1 (de) |
| CA (1) | CA2382117C (de) |
| CY (1) | CY1106716T1 (de) |
| DE (1) | DE60034577T2 (de) |
| DK (1) | DK1209151T3 (de) |
| ES (1) | ES2284519T3 (de) |
| PT (1) | PT1209151E (de) |
| WO (1) | WO2001016105A1 (de) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2002002526A1 (fr) * | 2000-07-03 | 2002-01-10 | Eisai Co., Ltd. | Compositions pharmaceutiques servant a stabiliser la tension intraoculaire |
| KR100579813B1 (ko) * | 2001-10-16 | 2006-05-12 | 주식회사 에스티씨나라 | 피페리딘 유도체, 이의 제조방법 및 이를 포함하는 치매치료용 약학적 조성물 |
| EP1466625A4 (de) * | 2001-12-28 | 2007-07-18 | Takeda Pharmaceutical | Vorbeugungs-/heilmittel für blasenstörungen |
| US20050107432A1 (en) * | 2002-01-22 | 2005-05-19 | Yoichi Iimura | Sigma receptor binder containing indanone derivative |
| HUP0401850A3 (en) * | 2004-09-15 | 2008-03-28 | Egis Gyogyszergyar Nyilvanosan | Donepezil salts for producing pharmaceutical composition |
| DE102004046497A1 (de) * | 2004-09-23 | 2006-04-06 | Helm Ag | Donepezil-Salze |
| AU2007333586A1 (en) | 2006-12-11 | 2008-06-19 | Reviva Pharmaceuticals, Inc. | Compositions, synthesis, and methods of using indanone based cholinesterase inhibitors |
| US9249098B2 (en) * | 2012-07-10 | 2016-02-02 | Xueheng Cheng | Derivatives of donepezil |
| CN103787954B (zh) * | 2012-10-26 | 2016-01-20 | 中国科学院上海药物研究所 | 一类氟取代的环状胺类化合物及其制备方法、药物组合物和用途 |
| US20140206667A1 (en) | 2012-11-14 | 2014-07-24 | Michela Gallagher | Methods and compositions for treating schizophrenia |
| JP6433482B2 (ja) | 2013-03-15 | 2018-12-05 | エージンバイオ， インコーポレイテッド | 認知機能を改善するための方法および組成物 |
| WO2014144663A1 (en) | 2013-03-15 | 2014-09-18 | The Johns Hopkins University | Methods and compositions for improving cognitive function |
| WO2016191288A1 (en) | 2015-05-22 | 2016-12-01 | Agenebio, Inc. | Extended release pharmaceutical compositions of levetiracetam |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2000319257A (ja) | 1969-01-06 | 2000-11-21 | Eisai Co Ltd | １−ベンジル−４−［（５，６−ジメトキシ−２−フルオロ−１−インダノン）−２−イル］メチルピペリジン |
| FI95572C (fi) | 1987-06-22 | 1996-02-26 | Eisai Co Ltd | Menetelmä lääkeaineena käyttökelpoisen piperidiinijohdannaisten tai sen farmaseuttisen suolan valmistamiseksi |
| US5750542A (en) | 1993-09-28 | 1998-05-12 | Pfizer | Benzisoxazole and benzisothizole derivatives as cholinesterase inhibitors |
| HU225047B1 (en) | 1991-03-28 | 2006-05-29 | Eisai Co Ltd | Heterocyclic-piperidin-derivatives, pharmaceutical compositions containing them and process for their production |
| EP0602242A4 (en) * | 1991-08-22 | 1994-06-29 | Yoshitomi Pharmaceutical | Benzisoxazole compound and use thereof. |
| JPH09268176A (ja) | 1996-04-01 | 1997-10-14 | Eisai Co Ltd | アラルキルピペリジン誘導体 |
| WO2000018391A1 (en) | 1998-09-30 | 2000-04-06 | Takeda Chemical Industries, Ltd. | Drugs for improving vesical excretory strength |
| US20020177593A1 (en) | 1998-09-30 | 2002-11-28 | Yuji Ishihara | Agents and crystals for improving excretory potency of urinary bladder |
| US6277866B1 (en) | 1999-03-03 | 2001-08-21 | Eisai Co., Ltd. | 1-benzyl-4[(5,6-dimethoxy-2-fluoro-1-indanon)-2-yl]methylpiperidine |
| US6677330B1 (en) | 1999-03-03 | 2004-01-13 | Eisai Co., Ltd. | Fluorides of 4-substituted piperidine derivatives |
| AU3924500A (en) | 1999-03-29 | 2000-10-16 | Schering Corporation | Methods and compositions for treating allergic and related disorders using fluorinated descarboethoxyloratadine |
| WO2002002526A1 (fr) | 2000-07-03 | 2002-01-10 | Eisai Co., Ltd. | Compositions pharmaceutiques servant a stabiliser la tension intraoculaire |
| IL150982A (en) * | 2002-07-30 | 2007-02-11 | Ori Lerman | Process for making Donafzil |
-
2000
- 2000-09-01 WO PCT/JP2000/005968 patent/WO2001016105A1/ja not_active Ceased
- 2000-09-01 ES ES00956885T patent/ES2284519T3/es not_active Expired - Lifetime
- 2000-09-01 US US10/069,073 patent/US7091218B1/en not_active Expired - Fee Related
- 2000-09-01 DK DK00956885T patent/DK1209151T3/da active
- 2000-09-01 CA CA002382117A patent/CA2382117C/en not_active Expired - Fee Related
- 2000-09-01 AT AT00956885T patent/ATE360612T1/de active
- 2000-09-01 DE DE60034577T patent/DE60034577T2/de not_active Expired - Lifetime
- 2000-09-01 EP EP00956885A patent/EP1209151B1/de not_active Expired - Lifetime
- 2000-09-01 PT PT00956885T patent/PT1209151E/pt unknown
-
2007
- 2007-07-10 CY CY20071100915T patent/CY1106716T1/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| CY1106716T1 (el) | 2012-05-23 |
| DK1209151T3 (da) | 2007-08-20 |
| WO2001016105A1 (en) | 2001-03-08 |
| ES2284519T3 (es) | 2007-11-16 |
| DE60034577D1 (de) | 2007-06-06 |
| DE60034577T2 (de) | 2007-12-27 |
| EP1209151A4 (de) | 2004-12-29 |
| EP1209151B1 (de) | 2007-04-25 |
| US7091218B1 (en) | 2006-08-15 |
| CA2382117C (en) | 2009-11-10 |
| PT1209151E (pt) | 2007-05-31 |
| EP1209151A1 (de) | 2002-05-29 |
| CA2382117A1 (en) | 2001-03-08 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification |
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