ATE462801T1 - Konkatamere ligationsprodukte: zusammensetzungen, verfahren und kits dafür - Google Patents
Konkatamere ligationsprodukte: zusammensetzungen, verfahren und kits dafürInfo
- Publication number
- ATE462801T1 ATE462801T1 AT04800900T AT04800900T ATE462801T1 AT E462801 T1 ATE462801 T1 AT E462801T1 AT 04800900 T AT04800900 T AT 04800900T AT 04800900 T AT04800900 T AT 04800900T AT E462801 T1 ATE462801 T1 AT E462801T1
- Authority
- AT
- Austria
- Prior art keywords
- present teachings
- methods
- compositions
- kits
- concatameric
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 4
- 239000000203 mixture Substances 0.000 title abstract 3
- 108091033319 polynucleotide Proteins 0.000 abstract 4
- 102000040430 polynucleotide Human genes 0.000 abstract 4
- 239000002157 polynucleotide Substances 0.000 abstract 4
- 239000000523 sample Substances 0.000 abstract 2
- 108091034117 Oligonucleotide Proteins 0.000 abstract 1
- JLCPHMBAVCMARE-UHFFFAOYSA-N [3-[[3-[[3-[[3-[[3-[[3-[[3-[[3-[[3-[[3-[[3-[[5-(2-amino-6-oxo-1H-purin-9-yl)-3-[[3-[[3-[[3-[[3-[[3-[[5-(2-amino-6-oxo-1H-purin-9-yl)-3-[[5-(2-amino-6-oxo-1H-purin-9-yl)-3-hydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methyl [5-(6-aminopurin-9-yl)-2-(hydroxymethyl)oxolan-3-yl] hydrogen phosphate Polymers Cc1cn(C2CC(OP(O)(=O)OCC3OC(CC3OP(O)(=O)OCC3OC(CC3O)n3cnc4c3nc(N)[nH]c4=O)n3cnc4c3nc(N)[nH]c4=O)C(COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3CO)n3cnc4c(N)ncnc34)n3ccc(N)nc3=O)n3cnc4c(N)ncnc34)n3ccc(N)nc3=O)n3ccc(N)nc3=O)n3ccc(N)nc3=O)n3cnc4c(N)ncnc34)n3cnc4c(N)ncnc34)n3cc(C)c(=O)[nH]c3=O)n3cc(C)c(=O)[nH]c3=O)n3ccc(N)nc3=O)n3cc(C)c(=O)[nH]c3=O)n3cnc4c3nc(N)[nH]c4=O)n3cnc4c(N)ncnc34)n3cnc4c(N)ncnc34)n3cnc4c(N)ncnc34)n3cnc4c(N)ncnc34)O2)c(=O)[nH]c1=O JLCPHMBAVCMARE-UHFFFAOYSA-N 0.000 abstract 1
- 238000004458 analytical method Methods 0.000 abstract 1
- 230000000295 complement effect Effects 0.000 abstract 1
- 238000001514 detection method Methods 0.000 abstract 1
- 238000011002 quantification Methods 0.000 abstract 1
- 239000011541 reaction mixture Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P19/00—Preparation of compounds containing saccharide radicals
- C12P19/26—Preparation of nitrogen-containing carbohydrates
- C12P19/28—N-glycosides
- C12P19/30—Nucleotides
- C12P19/34—Polynucleotides, e.g. nucleic acids, oligoribonucleotides
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6816—Hybridisation assays characterised by the detection means
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/156—Polymorphic or mutational markers
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Zoology (AREA)
- Engineering & Computer Science (AREA)
- Wood Science & Technology (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Genetics & Genomics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- General Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Immunology (AREA)
- Biophysics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Macromonomer-Based Addition Polymer (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US51747003P | 2003-11-04 | 2003-11-04 | |
| PCT/US2004/037284 WO2005047547A1 (en) | 2003-11-04 | 2004-11-04 | Concatameric ligation products: compositions, methods and kits for same |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE462801T1 true ATE462801T1 (de) | 2010-04-15 |
Family
ID=34590160
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT04800900T ATE462801T1 (de) | 2003-11-04 | 2004-11-04 | Konkatamere ligationsprodukte: zusammensetzungen, verfahren und kits dafür |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US7208278B2 (de) |
| EP (2) | EP2204458A1 (de) |
| AT (1) | ATE462801T1 (de) |
| DE (1) | DE602004026338D1 (de) |
| WO (1) | WO2005047547A1 (de) |
Families Citing this family (30)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2004046343A2 (en) * | 2002-11-19 | 2004-06-03 | Applera Corporation | Polynucleotide sequence detection assays and analysis |
| WO2004065582A2 (en) * | 2003-01-15 | 2004-08-05 | Dana-Farber Cancer Institute, Inc. | Amplification of dna in a hairpin structure, and applications |
| US20070099228A1 (en) * | 2004-11-04 | 2007-05-03 | Applera Corporation | Concatameric Ligation Products: Compositions, Methods and Kits for Same |
| WO2005108618A2 (en) * | 2004-04-30 | 2005-11-17 | Applera Corporation | Methods and kits for methylation detection |
| US7575863B2 (en) | 2004-05-28 | 2009-08-18 | Applied Biosystems, Llc | Methods, compositions, and kits comprising linker probes for quantifying polynucleotides |
| WO2006005055A2 (en) * | 2004-06-30 | 2006-01-12 | Applera Corporation | Methods reaction mixtures and kits for ligating polynucleotides |
| EP1791982B1 (de) * | 2004-09-21 | 2011-01-05 | Life Technologies Corporation | Zweifarbige echtzeit/endpunkt-quantifizierung von mikro-rnas (mirnas) |
| US20060211000A1 (en) * | 2005-03-21 | 2006-09-21 | Sorge Joseph A | Methods, compositions, and kits for detection of microRNA |
| US20070128620A1 (en) * | 2005-07-15 | 2007-06-07 | Applera Corporation | Hot start reverse transcription by primer design |
| US20070196849A1 (en) * | 2006-02-22 | 2007-08-23 | Applera Corporation | Double-ligation Method for Haplotype and Large-scale Polymorphism Detection |
| EP2021514A2 (de) | 2006-05-10 | 2009-02-11 | Dxterity Diagnostics | Erkennung von nukleinsäuretargets mithilfe chemisch reaktiver oligonnucleotid-sonden |
| US7833716B2 (en) | 2006-06-06 | 2010-11-16 | Gen-Probe Incorporated | Tagged oligonucleotides and their use in nucleic acid amplification methods |
| CA2687218A1 (en) * | 2007-05-14 | 2008-11-27 | Insight Genetics, Inc. | Methods of screening nucleic acids for single nucleotide variations |
| US8008010B1 (en) | 2007-06-27 | 2011-08-30 | Applied Biosystems, Llc | Chimeric oligonucleotides for ligation-enhanced nucleic acid detection, methods and compositions therefor |
| US9909170B2 (en) | 2008-09-05 | 2018-03-06 | Washington University | Method for multiplexed nucleic acid patch polymerase chain reaction |
| US8586310B2 (en) | 2008-09-05 | 2013-11-19 | Washington University | Method for multiplexed nucleic acid patch polymerase chain reaction |
| US11111514B2 (en) | 2008-09-05 | 2021-09-07 | Washington University | Method for multiplexed nucleic acid patch polymerase chain reaction |
| EP2765205B1 (de) * | 2009-04-01 | 2016-05-18 | DxTerity Diagnostics Incorporated | Chemische ligationsabhängige Sondenamplifizierung (CLPA) |
| CN106434871B (zh) | 2011-05-17 | 2020-08-18 | 德克斯特里蒂诊断公司 | 用于检测目标核酸的方法与组合物 |
| EP2970922B1 (de) * | 2013-03-15 | 2017-12-13 | Theranos, Inc. | Wärmestabile offenendige ligase und verfahren zur verwendung |
| GB2520763A (en) * | 2013-12-02 | 2015-06-03 | Vanadis Diagnostics Ab | Nucleic acid probe and method of detecting genomic fragments |
| GB2520765A (en) | 2013-12-02 | 2015-06-03 | Vanadis Diagnostics Ab | Multiplex detection of nucleic acids |
| CA2951561C (en) | 2014-06-10 | 2023-04-18 | Dxterity Diagnostics Incorporated | Devices and methods for collecting and stabilizing biological samples |
| EP3670671B1 (de) | 2015-09-18 | 2023-07-26 | Vanadis Diagnostics | Sondensatz zur analyse einer dna-probe und verfahren zur verwendung davon |
| US11208649B2 (en) | 2015-12-07 | 2021-12-28 | Zymergen Inc. | HTP genomic engineering platform |
| US9988624B2 (en) | 2015-12-07 | 2018-06-05 | Zymergen Inc. | Microbial strain improvement by a HTP genomic engineering platform |
| US11151497B2 (en) | 2016-04-27 | 2021-10-19 | Zymergen Inc. | Microbial strain design system and methods for improved large-scale production of engineered nucleotide sequences |
| US20230242971A1 (en) * | 2020-05-08 | 2023-08-03 | Roche Sequencing Solutions, Inc. | Removal of excess oligonucleotides from a reation mixture |
| EP4392554A1 (de) * | 2021-08-23 | 2024-07-03 | DNA Script | Verfahren zur erzeugung von doppelsträngiger nukleinsäure |
| EP4410995A1 (de) * | 2023-02-01 | 2024-08-07 | 4basebio, S.L.U. | Lineare dns mit erhöhter resistenz gegen exonukleasen und verfahren zu ihrer herstellung |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6235502B1 (en) * | 1998-09-18 | 2001-05-22 | Molecular Staging Inc. | Methods for selectively isolating DNA using rolling circle amplification |
| WO2001040516A2 (en) * | 1999-12-02 | 2001-06-07 | Molecular Staging Inc. | Generation of single-strand circular dna from linear self-annealing segments |
-
2004
- 2004-11-04 AT AT04800900T patent/ATE462801T1/de not_active IP Right Cessation
- 2004-11-04 EP EP10000934A patent/EP2204458A1/de not_active Withdrawn
- 2004-11-04 DE DE602004026338T patent/DE602004026338D1/de not_active Expired - Lifetime
- 2004-11-04 EP EP04800900A patent/EP1680517B1/de not_active Expired - Lifetime
- 2004-11-04 US US10/982,619 patent/US7208278B2/en not_active Expired - Lifetime
- 2004-11-04 WO PCT/US2004/037284 patent/WO2005047547A1/en not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| EP1680517B1 (de) | 2010-03-31 |
| EP2204458A1 (de) | 2010-07-07 |
| WO2005047547A1 (en) | 2005-05-26 |
| US7208278B2 (en) | 2007-04-24 |
| DE602004026338D1 (de) | 2010-05-12 |
| US20060063163A1 (en) | 2006-03-23 |
| EP1680517A1 (de) | 2006-07-19 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |