ATE306562T1 - Verfahren zur analyse von wiederkehrenden pcr- podukten, das auf der analyse von dns- schmelzkurven basiert - Google Patents

Verfahren zur analyse von wiederkehrenden pcr- podukten, das auf der analyse von dns- schmelzkurven basiert

Info

Publication number
ATE306562T1
ATE306562T1 AT01126930T AT01126930T ATE306562T1 AT E306562 T1 ATE306562 T1 AT E306562T1 AT 01126930 T AT01126930 T AT 01126930T AT 01126930 T AT01126930 T AT 01126930T AT E306562 T1 ATE306562 T1 AT E306562T1
Authority
AT
Austria
Prior art keywords
analysis
recurrent
analyzing
pcr products
products based
Prior art date
Application number
AT01126930T
Other languages
English (en)
Inventor
Wolfgang Dr Dietmaier
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Application granted granted Critical
Publication of ATE306562T1 publication Critical patent/ATE306562T1/de

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6827—Hybridisation assays for detection of mutation or polymorphism

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Immunology (AREA)
  • Physics & Mathematics (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
AT01126930T 2000-11-15 2001-11-13 Verfahren zur analyse von wiederkehrenden pcr- podukten, das auf der analyse von dns- schmelzkurven basiert ATE306562T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP00124897 2000-11-15

Publications (1)

Publication Number Publication Date
ATE306562T1 true ATE306562T1 (de) 2005-10-15

Family

ID=8170382

Family Applications (1)

Application Number Title Priority Date Filing Date
AT01126930T ATE306562T1 (de) 2000-11-15 2001-11-13 Verfahren zur analyse von wiederkehrenden pcr- podukten, das auf der analyse von dns- schmelzkurven basiert

Country Status (4)

Country Link
US (1) US6664064B1 (de)
JP (1) JP3844996B2 (de)
AT (1) ATE306562T1 (de)
DE (1) DE60113945T2 (de)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE60229890D1 (de) 2002-09-30 2008-12-24 Hoffmann La Roche Oligonukleotide zur genotypisierung des thymidylat-synthase gens
CA2504911C (en) * 2002-12-06 2015-08-11 Innogenetics N.V. Detection, identification and differentiation of eubacterial taxa using a hybridization assay
JP4571786B2 (ja) * 2003-06-10 2010-10-27 則夫 清水 標的核酸の検出法
US20050255483A1 (en) * 2004-05-14 2005-11-17 Stratagene California System and method for smoothing melting curve data
WO2006070666A1 (ja) * 2004-12-28 2006-07-06 Takara Bio Inc. 遺伝子多型の同時検出方法
US7977108B2 (en) * 2005-07-25 2011-07-12 Roche Molecular Systems, Inc. Method for detecting a mutation in a repetitive nucleic acid sequence
EP3167900B1 (de) 2006-03-29 2018-11-21 Merial Limited Impfstoff gegen streptokokken
CN101896623B (zh) * 2007-10-22 2013-12-18 Lgc有限公司 寡核苷酸及其应用
US20090181391A1 (en) * 2007-11-01 2009-07-16 Zymo Research Corporation Methods for analysis of dna methylation percentage
CN102076849A (zh) * 2008-12-16 2011-05-25 爱科来株式会社 核酸扩增的对照的检测方法及其用途
JP5917248B2 (ja) 2011-05-09 2016-05-11 アークレイ株式会社 ＨＧＦ遺伝子のｐｏｌｙＡｒｅｐｅａｔ数変異多型検出用プローブおよびその用途
CN102409088B (zh) * 2011-09-22 2014-11-12 郭奇伟 一种基因拷贝数变异的检测方法
CN103998921B (zh) 2011-10-14 2016-04-20 贝克顿·迪金森公司 方波热循环
US10633707B2 (en) 2012-04-10 2020-04-28 Vib Vzw Markers for detecting microsatellite instability in cancer and determining synthetic lethality with inhibition of the DNA base excision repair pathway
US10294529B2 (en) 2012-04-10 2019-05-21 Life Sciences Research Partners Vzw Microsatellite instability markers in detection of cancer
EP3998347A1 (de) * 2012-04-10 2022-05-18 Vib Vzw Neuartige marker für den nachweis von mikrosatelliteninstabilität bei krebs und die bestimmung von synthetischer letalität mit hemmung des dna-basen-exzisionsreparatursignalweges
AU2013202808B2 (en) 2012-07-31 2014-11-13 Gen-Probe Incorporated System and method for performing multiplex thermal melt analysis
KR102648647B1 (ko) * 2015-09-22 2024-03-18 비오까르띠 엔브이 짧은 호모폴리머릭 반복서열의 개선된 검출법
US11332781B2 (en) 2016-06-23 2022-05-17 Canon U.S.A., Inc. Fitting melting curve data to determine copy number variation
KR101969971B1 (ko) * 2017-03-24 2019-04-18 주식회사 시선바이오머티리얼스 양기능성 pna 프로브를 이용한 융해곡선 분석방법, 및 이를 이용한 현미부수체 불안정성의 진단방법 및 현미부수체 불안정성 진단용 키트
DE102018213587A1 (de) 2018-08-13 2020-02-13 Robert Bosch Gmbh Verfahren zum Bestimmen einer Spezifität einer Echtzeit-Polymerase-Kettenreaktion mit einer Schmelzkurvenanalyse

Family Cites Families (12)

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Publication number Priority date Publication date Assignee Title
US5075217A (en) * 1989-04-21 1991-12-24 Marshfield Clinic Length polymorphisms in (dC-dA)n ·(dG-dT)n sequences
US5582979A (en) * 1989-04-21 1996-12-10 Marshfield Clinic Length polymorphisms in (dC-dA)n.(dG-dT)n sequences and method of using the same
US6218119B1 (en) * 1996-01-16 2001-04-17 Keygene, N. V. Amplification of simple sequence repeats
CA2244700A1 (en) * 1996-01-26 1997-07-31 Abbott Laboratories Method for analyzing repeat nucleic acid sequences
US6238866B1 (en) * 1996-04-16 2001-05-29 The United States Of America As Represented By The Secretary Of The Army Detector for nucleic acid typing and methods of using the same
AUPO229596A0 (en) * 1996-09-12 1996-10-03 Varian Australia Pty Ltd Method for analysis of DNA
GB2333597B (en) * 1996-10-29 2001-04-18 Univ Nebraska At Lincoln Method for detecting point mutations in dna utilizing fluorescence energy transfer
WO1998023776A1 (en) * 1996-11-29 1998-06-04 Amersham Pharmacia Biotech Uk Ltd. Method for determining tandem repeat sequence length
AUPO882497A0 (en) * 1997-08-29 1997-09-18 Grains Research & Development Corporation A method of genotyping
US6140054A (en) * 1998-09-30 2000-10-31 University Of Utah Research Foundation Multiplex genotyping using fluorescent hybridization probes
EP1207210B1 (de) * 2000-11-15 2005-10-12 Roche Diagnostics GmbH Verfahren zur Analyse von Wiederkehrenden PCR-Podukten, das auf der Analyse von DNS-Schmelzkurven basiert
JP2003093075A (ja) * 2001-09-26 2003-04-02 Adgene Co Ltd 電気抵抗を利用した核酸変異検出法

Also Published As

Publication number Publication date
JP2002191384A (ja) 2002-07-09
JP3844996B2 (ja) 2006-11-15
US6664064B1 (en) 2003-12-16
DE60113945T2 (de) 2006-06-29
DE60113945D1 (de) 2005-11-17

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