ATE465163T1 - Heterocyclische verbindungen, ihre herstellung und ihre verwendung als antibakterielle mittel - Google Patents

Heterocyclische verbindungen, ihre herstellung und ihre verwendung als antibakterielle mittel

Info

Publication number
ATE465163T1
ATE465163T1 AT06831388T AT06831388T ATE465163T1 AT E465163 T1 ATE465163 T1 AT E465163T1 AT 06831388 T AT06831388 T AT 06831388T AT 06831388 T AT06831388 T AT 06831388T AT E465163 T1 ATE465163 T1 AT E465163T1
Authority
AT
Austria
Prior art keywords
preparation
antibacterial agents
heterocyclic compounds
heterocyclic
antibacterial
Prior art date
Application number
AT06831388T
Other languages
English (en)
Inventor
Nathalie Cailleau
David Davies
Alan Hennessy
Graham Jones
Timothy Miles
Neil Pearson
Original Assignee
Glaxo Group Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxo Group Ltd filed Critical Glaxo Group Ltd
Application granted granted Critical
Publication of ATE465163T1 publication Critical patent/ATE465163T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
    • C07D471/16—Peri-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
AT06831388T 2005-12-22 2006-12-15 Heterocyclische verbindungen, ihre herstellung und ihre verwendung als antibakterielle mittel ATE465163T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US75314905P 2005-12-22 2005-12-22
US86687706P 2006-11-22 2006-11-22
PCT/GB2006/004686 WO2007071936A1 (en) 2005-12-22 2006-12-15 Heterocyclic compounds, their preparation and their use as antibacterials

Publications (1)

Publication Number Publication Date
ATE465163T1 true ATE465163T1 (de) 2010-05-15

Family

ID=37763790

Family Applications (1)

Application Number Title Priority Date Filing Date
AT06831388T ATE465163T1 (de) 2005-12-22 2006-12-15 Heterocyclische verbindungen, ihre herstellung und ihre verwendung als antibakterielle mittel

Country Status (10)

Country Link
US (2) US7732460B2 (de)
EP (1) EP1963324B1 (de)
JP (1) JP2009520779A (de)
AR (1) AR058587A1 (de)
AT (1) ATE465163T1 (de)
DE (1) DE602006013878D1 (de)
ES (1) ES2344523T3 (de)
PE (1) PE20071064A1 (de)
TW (1) TW200801001A (de)
WO (1) WO2007071936A1 (de)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20080064173A (ko) * 2005-10-21 2008-07-08 글락소 그룹 리미티드 항균제로서 유용한 페리 축합 트리시클릭 화합물
WO2007115947A1 (en) 2006-04-06 2007-10-18 Glaxo Group Limited Pyrrolo-quinoxalinone derivatives as antibacterials
GB0608263D0 (en) 2006-04-26 2006-06-07 Glaxo Group Ltd Compounds
GB0613208D0 (en) * 2006-07-03 2006-08-09 Glaxo Group Ltd Compounds
GB0705672D0 (en) * 2007-03-23 2007-05-02 Glaxo Group Ltd Compounds
CL2008001002A1 (es) 2007-04-11 2008-10-17 Actelion Pharmaceuticals Ltd Compuestos derivados de oxazolidinona; composicion farmaceutica que comprende a dichos compuestos; y su uso para preparar un medicamento para tratar una infeccion bacteriana.
EA015821B1 (ru) * 2007-04-20 2011-12-30 Глэксо Груп Лимитед Трициклические азотсодержащие соединения в качестве антибактериальных агентов
GB0707706D0 (en) * 2007-04-20 2007-05-30 Glaxo Group Ltd Compounds
EP2005995A1 (de) * 2007-06-22 2008-12-24 Glaxo Group Limited Heterocyclische Verbindungen für die Behandlung von Tuberkulose
CN101874032B (zh) * 2007-11-26 2013-02-06 富山化学工业株式会社 二氮杂萘衍生物一水合物及其制备方法
EP2080761A1 (de) 2008-01-18 2009-07-22 Glaxo Group Limited Verbindungen
ES2411930T3 (es) * 2008-02-20 2013-07-09 Actelion Pharmaceuticals Ltd. Compuestos antibióticos azatricíclicos
RU2501799C2 (ru) 2008-02-22 2013-12-20 Актелион Фармасьютикалз Лтд Поизводные оксазолидинона
WO2009125808A1 (ja) * 2008-04-11 2009-10-15 第一三共株式会社 アミノシクロヘキシル誘導体
WO2009125809A1 (ja) * 2008-04-11 2009-10-15 第一三共株式会社 ピペリジン誘導体
EP2276766A1 (de) 2008-04-15 2011-01-26 Actelion Pharmaceuticals Ltd. Tricyclische antibiotika
BRPI0912995A2 (pt) * 2008-05-23 2015-10-13 Glaxo Group Ltd compostos tricíclicos contendo nitrogênio e sua utilização como agentes antibacterianos
JP2011520944A (ja) * 2008-05-23 2011-07-21 グラクソ グループ リミテッド 窒素含有三環式化合物および抗菌剤としてのその使用
BRPI0920895A8 (pt) 2008-10-07 2017-12-26 Actelion Pharmaceuticals Ltd Compostos antibióticos de oxazolidinona tricíclica
WO2010043714A1 (en) 2008-10-17 2010-04-22 Glaxo Group Limited Tricyclic nitrogen compounds used as antibacterials
CN102232078B (zh) 2008-12-12 2014-07-16 埃科特莱茵药品有限公司 5-氨基-2-(1-羟基-乙基)-四氢吡喃衍生物
ES2561631T3 (es) 2009-01-15 2016-02-29 Glaxo Group Limited Compuestos de naftiridin-2(1H)-ona útiles como agentes antibacterianos
AR087875A1 (es) 2011-09-16 2014-04-23 Actelion Pharmaceuticals Ltd Proceso para la elaboracion de derivados de piridazina como intermediarios de sintesis de antibioticos
CA2854266A1 (en) 2011-11-30 2013-06-06 Actelion Pharmaceuticals Ltd 3,7-disubstituted octahydro-2h-pyrido[4,3-e][1,3]oxazin-2-one antibiotics
JP6546654B2 (ja) 2014-08-22 2019-07-17 グラクソスミスクライン、インテレクチュアル、プロパティー、ディベロップメント、リミテッドＧｌａｘｏｓｍｉｔｈｋｌｉｎｅ Ｉｎｔｅｌｌｅｃｔｕａｌ Ｐｒｏｐｅｒｔｙ Ｄｅｖｅｌｏｐｍｅｎｔ Ｌｉｍｉｔｅｄ 淋菌感染を治療するための三環式含窒素化合物

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9622386D0 (en) 1996-10-28 1997-01-08 Sandoz Ltd Organic compounds
GB0101577D0 (en) 2001-01-22 2001-03-07 Smithkline Beecham Plc Compounds
GB0112836D0 (en) * 2001-05-25 2001-07-18 Smithkline Beecham Plc Medicaments
WO2003064431A2 (en) 2002-01-29 2003-08-07 Glaxo Group Limited Aminopiperidine compounds, process for their preparation, and pharmaceutical compositions containing them
US7196090B2 (en) 2002-07-25 2007-03-27 Warner-Lambert Company Kinase inhibitors
ATE423117T1 (de) 2003-09-22 2009-03-15 Janssen Pharmaceutica Nv Heterocyclische 7-aminoalkylidenylchinolone und - naphthyridone
US7732612B2 (en) 2004-09-09 2010-06-08 Janssen Pharmaceutica, N.V. 7-amino alkylidenyl-heterocyclic quinolones and naphthyridones
KR20080064173A (ko) 2005-10-21 2008-07-08 글락소 그룹 리미티드 항균제로서 유용한 페리 축합 트리시클릭 화합물
WO2007115947A1 (en) 2006-04-06 2007-10-18 Glaxo Group Limited Pyrrolo-quinoxalinone derivatives as antibacterials
GB0608263D0 (en) 2006-04-26 2006-06-07 Glaxo Group Ltd Compounds
GB0613208D0 (en) 2006-07-03 2006-08-09 Glaxo Group Ltd Compounds

Also Published As

Publication number Publication date
DE602006013878D1 (de) 2010-06-02
WO2007071936A1 (en) 2007-06-28
US20090036433A1 (en) 2009-02-05
US20070185153A1 (en) 2007-08-09
TW200801001A (en) 2008-01-01
JP2009520779A (ja) 2009-05-28
PE20071064A1 (es) 2007-12-16
EP1963324A1 (de) 2008-09-03
AR058587A1 (es) 2008-02-13
ES2344523T3 (es) 2010-08-30
EP1963324B1 (de) 2010-04-21
US7732460B2 (en) 2010-06-08

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