ATE465267T1 - Rekombinante aav zur herstellung eines medikaments für die gentherapie von muskelzellen - Google Patents

Rekombinante aav zur herstellung eines medikaments für die gentherapie von muskelzellen

Info

Publication number
ATE465267T1
ATE465267T1 AT06006222T AT06006222T ATE465267T1 AT E465267 T1 ATE465267 T1 AT E465267T1 AT 06006222 T AT06006222 T AT 06006222T AT 06006222 T AT06006222 T AT 06006222T AT E465267 T1 ATE465267 T1 AT E465267T1
Authority
AT
Austria
Prior art keywords
medicine
producing
gene therapy
muscle cells
recombinant aav
Prior art date
Application number
AT06006222T
Other languages
English (en)
Inventor
James M Wilson
Krishna J Fisher
Original Assignee
Univ Pennsylvania
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US08/708,188 external-priority patent/US5866552A/en
Application filed by Univ Pennsylvania filed Critical Univ Pennsylvania
Application granted granted Critical
Publication of ATE465267T1 publication Critical patent/ATE465267T1/de

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C12N15/86—Viral vectors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2750/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssDNA viruses
    • C12N2750/00011—Details
    • C12N2750/14011—Parvoviridae
    • C12N2750/14111—Dependovirus, e.g. adenoassociated viruses
    • C12N2750/14141—Use of virus, viral particle or viral elements as a vector
    • C12N2750/14143—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Wood Science & Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Microbiology (AREA)
  • Plant Pathology (AREA)
  • Biochemistry (AREA)
  • Physics & Mathematics (AREA)
  • Virology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
AT06006222T 1996-09-06 1997-09-04 Rekombinante aav zur herstellung eines medikaments für die gentherapie von muskelzellen ATE465267T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/708,188 US5866552A (en) 1996-09-06 1996-09-06 Method for expressing a gene in the absence of an immune response
US72906196A 1996-10-10 1996-10-10

Publications (1)

Publication Number Publication Date
ATE465267T1 true ATE465267T1 (de) 2010-05-15

Family

ID=27108032

Family Applications (2)

Application Number Title Priority Date Filing Date
AT97943290T ATE380037T1 (de) 1996-09-06 1997-09-04 Verfaheren zur durch rekombinante adeno- assoziierte virus-gerichtete gentherapie
AT06006222T ATE465267T1 (de) 1996-09-06 1997-09-04 Rekombinante aav zur herstellung eines medikaments für die gentherapie von muskelzellen

Family Applications Before (1)

Application Number Title Priority Date Filing Date
AT97943290T ATE380037T1 (de) 1996-09-06 1997-09-04 Verfaheren zur durch rekombinante adeno- assoziierte virus-gerichtete gentherapie

Country Status (11)

Country Link
EP (2) EP0932418B1 (de)
JP (1) JP2001500497A (de)
KR (1) KR20000068501A (de)
CN (1) CN1233291A (de)
AT (2) ATE380037T1 (de)
AU (1) AU723497C (de)
CA (1) CA2264483C (de)
DE (2) DE69739860D1 (de)
ES (1) ES2344660T3 (de)
IL (1) IL128779A0 (de)
WO (1) WO1998009657A2 (de)

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WO1998009657A2 (en) 1998-03-12
EP1696036B1 (de) 2010-04-21
EP1696036A1 (de) 2006-08-30
KR20000068501A (ko) 2000-11-25
AU723497C (en) 2001-10-11
IL128779A0 (en) 2000-01-31
DE69738351T2 (de) 2008-11-13
ATE380037T1 (de) 2007-12-15
AU4479597A (en) 1998-03-26
CA2264483A1 (en) 1998-03-12
AU723497B2 (en) 2000-08-31
ES2344660T3 (es) 2010-09-02
CA2264483C (en) 2011-03-22
EP0932418A2 (de) 1999-08-04
DE69738351D1 (de) 2008-01-17
CN1233291A (zh) 1999-10-27
DE69739860D1 (de) 2010-06-02
WO1998009657A3 (en) 1998-04-23
EP0932418B1 (de) 2007-12-05

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