ATE467424T1 - Escape-mutanten des newcastle-disease-virus als marker-vakzine - Google Patents

Escape-mutanten des newcastle-disease-virus als marker-vakzine

Info

Publication number
ATE467424T1
ATE467424T1 AT03796596T AT03796596T ATE467424T1 AT E467424 T1 ATE467424 T1 AT E467424T1 AT 03796596 T AT03796596 T AT 03796596T AT 03796596 T AT03796596 T AT 03796596T AT E467424 T1 ATE467424 T1 AT E467424T1
Authority
AT
Austria
Prior art keywords
disease virus
newcastle disease
escape mutants
marker vaccines
vaccines
Prior art date
Application number
AT03796596T
Other languages
English (en)
Inventor
Harmen Geerligs
Ian Hamer Brown
Dennis John Alexander
Michael Sinclair Collins
Original Assignee
Wyeth Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wyeth Llc filed Critical Wyeth Llc
Application granted granted Critical
Publication of ATE467424T1 publication Critical patent/ATE467424T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A61K39/155—Paramyxoviridae, e.g. parainfluenza virus
    • A61K39/17—Newcastle disease virus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/08—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from viruses
    • C07K16/10—RNA viruses
    • C07K16/11—Paramyxoviridae (F); Pneumoviridae (F), e.g. respiratory syncytial virus [RSV]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/525—Virus
    • A61K2039/5254—Virus avirulent or attenuated
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/55—Medicinal preparations containing antigens or antibodies characterised by the host/recipient, e.g. newborn with maternal antibodies
    • A61K2039/552—Veterinary vaccine
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
    • C12N2760/00011—Details
    • C12N2760/18011—Paramyxoviridae
    • C12N2760/18111—Avulavirus, e.g. Newcastle disease virus
    • C12N2760/18122—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
    • C12N2760/00011—Details
    • C12N2760/18011—Paramyxoviridae
    • C12N2760/18111—Avulavirus, e.g. Newcastle disease virus
    • C12N2760/18134—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/005—Assays involving biological materials from specific organisms or of a specific nature from viruses
    • G01N2333/08—RNA viruses
    • G01N2333/115—Paramyxoviridae, e.g. parainfluenza virus
    • G01N2333/125—Newcastle disease virus

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Virology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Epidemiology (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Pulmonology (AREA)
  • Zoology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
AT03796596T 2002-12-06 2003-12-03 Escape-mutanten des newcastle-disease-virus als marker-vakzine ATE467424T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US43151902P 2002-12-06 2002-12-06
US47141903P 2003-05-15 2003-05-15
PCT/US2003/038414 WO2004052278A2 (en) 2002-12-06 2003-12-03 Escape mutants of newcastle disease virus as marker vaccines

Publications (1)

Publication Number Publication Date
ATE467424T1 true ATE467424T1 (de) 2010-05-15

Family

ID=32511574

Family Applications (1)

Application Number Title Priority Date Filing Date
AT03796596T ATE467424T1 (de) 2002-12-06 2003-12-03 Escape-mutanten des newcastle-disease-virus als marker-vakzine

Country Status (10)

Country Link
US (2) US6833133B2 (de)
EP (1) EP1578374B1 (de)
JP (1) JP4785531B2 (de)
AR (1) AR042315A1 (de)
AT (1) ATE467424T1 (de)
AU (1) AU2003298838A1 (de)
CA (1) CA2508139C (de)
DE (1) DE60332555D1 (de)
TW (1) TW200502402A (de)
WO (1) WO2004052278A2 (de)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101668857A (zh) * 2007-02-21 2010-03-10 诺瓦瓦克斯股份有限公司 嵌合的新城疫病毒vlp
WO2009102459A2 (en) * 2008-02-13 2009-08-20 Wyeth A genetic assay to identify newcastle disease virus escape mutants

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA874677B (en) * 1986-06-30 1988-11-30 Smith Kline Rit Dna sequence,recombinant dna molecules and process for producing the newcastle disease virus fusion protein or equivalent polypeptides,obtained products and preparations containing same
EP0351908B1 (de) 1988-07-18 1994-10-05 Duphar International Research B.V Lebende Newcastle-Krankheit-Virus-Vakzine
US5250298A (en) 1988-10-07 1993-10-05 University Of Delaware Live attenuated newcastle disease virus vaccines and preparation thereof
JP2781605B2 (ja) * 1989-06-22 1998-07-30 日本ゼオン株式会社 組み換えアビポックスウイルス
CA2181862C (en) 1995-08-01 2009-12-22 Carla Christina Schrier Mild newcastle disease virus vaccine
EP0770397B1 (de) 1995-10-18 2004-04-21 Akzo Nobel N.V. Newcastle-Krankheitsvirus-Kombinationsimpfstoff
EP0848956A1 (de) 1996-12-17 1998-06-24 Dimminaco Ag/Sa/Ltd. In ovo Impfung gegen die Newcastle-Krankheit
WO1999002695A2 (en) * 1997-07-08 1999-01-21 Stichting Instituut Voor Dierhouderij En Diergezondheid Epitopes and active sites of paramyxoviridae proteins and uses thereof
EP0974660A1 (de) * 1998-06-19 2000-01-26 Stichting Instituut voor Dierhouderij en Diergezondheid (ID-DLO) Newcastle-Krankheitsvirus Infektiöser Klone, Impfstoffe und Diagnosetest
WO2002036617A2 (en) 2000-11-02 2002-05-10 Akzo Nobel N.V. A recombinant newcastle disease virus nucleoprotein mutant as a marker vaccine

Also Published As

Publication number Publication date
EP1578374A2 (de) 2005-09-28
EP1578374B1 (de) 2010-05-12
DE60332555D1 (en) 2010-06-24
AR042315A1 (es) 2005-06-15
AU2003298838A8 (en) 2004-06-30
WO2004052278A2 (en) 2004-06-24
CA2508139C (en) 2009-09-22
US6833133B2 (en) 2004-12-21
WO2004052278A3 (en) 2004-09-16
TW200502402A (en) 2005-01-16
US20040131640A1 (en) 2004-07-08
US20050069561A1 (en) 2005-03-31
US7041299B2 (en) 2006-05-09
EP1578374A4 (de) 2006-12-13
CA2508139A1 (en) 2004-06-24
JP4785531B2 (ja) 2011-10-05
JP2006511619A (ja) 2006-04-06
AU2003298838A1 (en) 2004-06-30

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Legal Events

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