ATE467424T1 - Escape-mutanten des newcastle-disease-virus als marker-vakzine - Google Patents

Escape-mutanten des newcastle-disease-virus als marker-vakzine

Info

Publication number
ATE467424T1
ATE467424T1 AT03796596T AT03796596T ATE467424T1 AT E467424 T1 ATE467424 T1 AT E467424T1 AT 03796596 T AT03796596 T AT 03796596T AT 03796596 T AT03796596 T AT 03796596T AT E467424 T1 ATE467424 T1 AT E467424T1
Authority
AT
Austria
Prior art keywords
disease virus
newcastle disease
escape mutants
marker vaccines
vaccines
Prior art date
Application number
AT03796596T
Other languages
English (en)
Inventor
Harmen Geerligs
Ian Hamer Brown
Dennis John Alexander
Michael Sinclair Collins
Original Assignee
Wyeth Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wyeth Llc filed Critical Wyeth Llc
Application granted granted Critical
Publication of ATE467424T1 publication Critical patent/ATE467424T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/12Viral antigens
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/12Viral antigens
    • A61K39/155Paramyxoviridae, e.g. parainfluenza virus
    • A61K39/17Newcastle disease virus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/08Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from viruses
    • C07K16/10RNA viruses
    • C07K16/11Paramyxoviridae (F); Pneumoviridae (F), e.g. respiratory syncytial virus [RSV]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/51Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/525Virus
    • A61K2039/5254Virus avirulent or attenuated
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/55Medicinal preparations containing antigens or antibodies characterised by the host/recipient, e.g. newborn with maternal antibodies
    • A61K2039/552Veterinary vaccine
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2760/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
    • C12N2760/00011Details
    • C12N2760/18011Paramyxoviridae
    • C12N2760/18111Avulavirus, e.g. Newcastle disease virus
    • C12N2760/18122New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2760/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
    • C12N2760/00011Details
    • C12N2760/18011Paramyxoviridae
    • C12N2760/18111Avulavirus, e.g. Newcastle disease virus
    • C12N2760/18134Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/005Assays involving biological materials from specific organisms or of a specific nature from viruses
    • G01N2333/08RNA viruses
    • G01N2333/115Paramyxoviridae, e.g. parainfluenza virus
    • G01N2333/125Newcastle disease virus

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Virology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Epidemiology (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Pulmonology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
AT03796596T 2002-12-06 2003-12-03 Escape-mutanten des newcastle-disease-virus als marker-vakzine ATE467424T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US43151902P 2002-12-06 2002-12-06
US47141903P 2003-05-15 2003-05-15
PCT/US2003/038414 WO2004052278A2 (en) 2002-12-06 2003-12-03 Escape mutants of newcastle disease virus as marker vaccines

Publications (1)

Publication Number Publication Date
ATE467424T1 true ATE467424T1 (de) 2010-05-15

Family

ID=32511574

Family Applications (1)

Application Number Title Priority Date Filing Date
AT03796596T ATE467424T1 (de) 2002-12-06 2003-12-03 Escape-mutanten des newcastle-disease-virus als marker-vakzine

Country Status (10)

Country Link
US (2) US6833133B2 (de)
EP (1) EP1578374B1 (de)
JP (1) JP4785531B2 (de)
AR (1) AR042315A1 (de)
AT (1) ATE467424T1 (de)
AU (1) AU2003298838A1 (de)
CA (1) CA2508139C (de)
DE (1) DE60332555D1 (de)
TW (1) TW200502402A (de)
WO (1) WO2004052278A2 (de)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2678966A1 (en) * 2007-02-21 2008-08-28 Novavax, Inc. Chimeric newcastle disease virus vlps
WO2009102459A2 (en) * 2008-02-13 2009-08-20 Wyeth A genetic assay to identify newcastle disease virus escape mutants

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6324888A (ja) * 1986-06-30 1988-02-02 スミスクライン・ベックマン ― アニマル・ヘルス・プロダクツ・ソシエテ・アノニム 組換え型dna分子
ES2060740T3 (es) * 1988-07-18 1994-12-01 Duphar Int Res Vacunas de virus vivos para la enfermedad de newcastle.
US5250298A (en) * 1988-10-07 1993-10-05 University Of Delaware Live attenuated newcastle disease virus vaccines and preparation thereof
JP2781605B2 (ja) * 1989-06-22 1998-07-30 日本ゼオン株式会社 組み換えアビポックスウイルス
CA2181862C (en) * 1995-08-01 2009-12-22 Carla Christina Schrier Mild newcastle disease virus vaccine
DK0770397T3 (da) * 1995-10-18 2004-08-09 Akzo Nobel Nv Newcastle disease viruskombinationsvaccine
EP0848956A1 (de) * 1996-12-17 1998-06-24 Dimminaco Ag/Sa/Ltd. In ovo Impfung gegen die Newcastle-Krankheit
AU8246298A (en) * 1997-07-08 1999-02-08 Stichting Instituut Voor Dierhouderij En Diergezondheid Epitopes and active sites of paramyxoviridae proteins and uses thereof
EP0974660A1 (de) * 1998-06-19 2000-01-26 Stichting Instituut voor Dierhouderij en Diergezondheid (ID-DLO) Newcastle-Krankheitsvirus Infektiöser Klone, Impfstoffe und Diagnosetest
ES2278810T3 (es) * 2000-11-02 2007-08-16 Intervet International Bv Nucleoproteina recombinante mutante del virus de la enfermedad de newcastle (ndv) como marcador de vacuna.

Also Published As

Publication number Publication date
CA2508139A1 (en) 2004-06-24
EP1578374A4 (de) 2006-12-13
CA2508139C (en) 2009-09-22
AR042315A1 (es) 2005-06-15
DE60332555D1 (en) 2010-06-24
US20050069561A1 (en) 2005-03-31
EP1578374A2 (de) 2005-09-28
US6833133B2 (en) 2004-12-21
AU2003298838A1 (en) 2004-06-30
AU2003298838A8 (en) 2004-06-30
US7041299B2 (en) 2006-05-09
JP4785531B2 (ja) 2011-10-05
JP2006511619A (ja) 2006-04-06
EP1578374B1 (de) 2010-05-12
WO2004052278A2 (en) 2004-06-24
TW200502402A (en) 2005-01-16
US20040131640A1 (en) 2004-07-08
WO2004052278A3 (en) 2004-09-16

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