ATE468113T1 - Therapeutisches mittel für ein weichteilsarkom - Google Patents

Therapeutisches mittel für ein weichteilsarkom

Info

Publication number
ATE468113T1
ATE468113T1 AT04746840T AT04746840T ATE468113T1 AT E468113 T1 ATE468113 T1 AT E468113T1 AT 04746840 T AT04746840 T AT 04746840T AT 04746840 T AT04746840 T AT 04746840T AT E468113 T1 ATE468113 T1 AT E468113T1
Authority
AT
Austria
Prior art keywords
compound
formula
therapeutic agent
soft tissue
tissue sarcoma
Prior art date
Application number
AT04746840T
Other languages
English (en)
Inventor
Tatsuo Ito
Toshifumi Ozaki
Mamoru Ouchida
Original Assignee
Astellas Pharma Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astellas Pharma Inc filed Critical Astellas Pharma Inc
Application granted granted Critical
Publication of ATE468113T1 publication Critical patent/ATE468113T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/005—Enzyme inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4406—Non condensed pyridines; Hydrogenated derivatives thereof only substituted in position 3, e.g. zimeldine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/12—Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Saccharide Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
AT04746840T 2003-06-27 2004-06-25 Therapeutisches mittel für ein weichteilsarkom ATE468113T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2003183643 2003-06-27
PCT/JP2004/009371 WO2005000332A2 (en) 2003-06-27 2004-06-25 Therapeutic agent for soft tissue sarcoma

Publications (1)

Publication Number Publication Date
ATE468113T1 true ATE468113T1 (de) 2010-06-15

Family

ID=33549590

Family Applications (1)

Application Number Title Priority Date Filing Date
AT04746840T ATE468113T1 (de) 2003-06-27 2004-06-25 Therapeutisches mittel für ein weichteilsarkom

Country Status (14)

Country Link
US (2) US7056883B2 (de)
EP (2) EP1638541B1 (de)
JP (1) JP4661782B2 (de)
AT (1) ATE468113T1 (de)
CA (1) CA2529840A1 (de)
CY (1) CY1113534T1 (de)
DE (1) DE602004027244D1 (de)
DK (1) DK2238982T3 (de)
ES (2) ES2341771T3 (de)
MX (1) MXPA06000013A (de)
PL (1) PL2238982T3 (de)
PT (1) PT2238982E (de)
SI (1) SI2238982T1 (de)
WO (1) WO2005000332A2 (de)

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US7381825B2 (en) 2003-03-17 2008-06-03 Takeda San Diego, Inc. Histone deacetylase inhibitors
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US20070197568A1 (en) * 2005-11-04 2007-08-23 Paul Bunn Methods of using SAHA and Erlotinib for treating cancer
US20070129290A1 (en) * 2005-11-18 2007-06-07 Or Yat S Metabolite derivatives of the HDAC inhibitor FK228
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US8957027B2 (en) * 2006-06-08 2015-02-17 Celgene Corporation Deacetylase inhibitor therapy
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CN101687010A (zh) * 2006-12-29 2010-03-31 格洛斯特制药公司 制备Romidepsin
AU2007342028B2 (en) * 2006-12-29 2013-06-13 Celgene Corporation Purifiction of romidepsin
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NZ605526A (en) 2010-07-12 2015-04-24 Celgene Corp Romidepsin solid forms and uses thereof
US8859502B2 (en) 2010-09-13 2014-10-14 Celgene Corporation Therapy for MLL-rearranged leukemia
CA2863291A1 (en) * 2012-01-12 2013-07-18 Celgene Corporation Romidepsin formulations and uses thereof
AU2013202506B2 (en) 2012-09-07 2015-06-18 Celgene Corporation Resistance biomarkers for hdac inhibitors
CA2887243C (en) 2012-10-15 2024-04-09 Epizyme, Inc. Methods of treating cancer
AU2013202507B9 (en) 2012-11-14 2015-08-13 Celgene Corporation Inhibition of drug resistant cancer cells
US9410943B2 (en) 2013-03-14 2016-08-09 The Board Of Trustees Of The Leland Stanford Junior University Methods, compositions and screens for therapeutics for the treatment of synovial sarcoma
EP3616754A1 (de) 2013-08-22 2020-03-04 Vanda Pharmaceuticals Inc. Krebsbehandlung
EP3057594A4 (de) * 2013-10-18 2017-06-07 Epizyme, Inc. Verfahren zur behandlung von karzinomen
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MA40367A (fr) * 2014-07-03 2017-05-10 Imclone Llc Polythérapie
US10441644B2 (en) 2015-05-05 2019-10-15 The Regents Of The University Of California H3.3 CTL peptides and uses thereof
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EP3746135A4 (de) 2018-01-30 2022-03-09 Foghorn Therapeutics Inc. Verfahren und verbindungen zur behandlung von erkrankungen
CN113874016A (zh) 2019-01-29 2021-12-31 福宏治疗公司 化合物及其用途
EP3917517A4 (de) 2019-01-29 2023-01-25 Foghorn Therapeutics Inc. Verbindungen und verwendungen davon
US20230066136A1 (en) 2019-01-29 2023-03-02 Foghorn Therapeutics Inc. Compounds and uses thereof
US12384776B2 (en) 2019-01-29 2025-08-12 Foghorn Therapeutics Inc. Compounds and uses thereof
US20220154282A1 (en) * 2019-03-12 2022-05-19 The Broad Institute, Inc. Detection means, compositions and methods for modulating synovial sarcoma cells
WO2021022163A2 (en) 2019-07-31 2021-02-04 Foghorn Therapeutics Inc. Compounds and uses thereof
US12528825B2 (en) 2020-01-29 2026-01-20 Foghorn Therapeutics Inc. Compounds and uses thereof
EP4096651A4 (de) 2020-01-29 2024-01-24 Foghorn Therapeutics Inc. Verbindungen und verwendungen davon
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Also Published As

Publication number Publication date
EP1638541B1 (de) 2010-05-19
SI2238982T1 (sl) 2013-01-31
EP1638541A2 (de) 2006-03-29
JP2007521259A (ja) 2007-08-02
PT2238982E (pt) 2013-01-22
US20050107290A1 (en) 2005-05-19
US7056883B2 (en) 2006-06-06
JP4661782B2 (ja) 2011-03-30
CA2529840A1 (en) 2005-01-06
DE602004027244D1 (de) 2010-07-01
EP2238982B1 (de) 2012-10-17
EP2238982B8 (de) 2013-01-16
ES2341771T3 (es) 2010-06-28
EP2238982A3 (de) 2011-03-02
WO2005000332A3 (en) 2005-03-24
WO2005000332A2 (en) 2005-01-06
DK2238982T3 (da) 2013-01-28
ES2397079T3 (es) 2013-03-04
US20060223747A1 (en) 2006-10-05
MXPA06000013A (es) 2006-03-21
EP2238982A2 (de) 2010-10-13
CY1113534T1 (el) 2016-06-22
PL2238982T3 (pl) 2013-03-29

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