ATE468175T1 - Homogenisierung von kleinvolumigen mischungen durch zentrifugierung und erhitzen - Google Patents

Homogenisierung von kleinvolumigen mischungen durch zentrifugierung und erhitzen

Info

Publication number
ATE468175T1
ATE468175T1 AT00921255T AT00921255T ATE468175T1 AT E468175 T1 ATE468175 T1 AT E468175T1 AT 00921255 T AT00921255 T AT 00921255T AT 00921255 T AT00921255 T AT 00921255T AT E468175 T1 ATE468175 T1 AT E468175T1
Authority
AT
Austria
Prior art keywords
heating
reaction vessels
rotor
elements
centrifugation
Prior art date
Application number
AT00921255T
Other languages
English (en)
Inventor
Mats Malmquist
Original Assignee
Alphahelix Molecular Diagnosti
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from SE9901104A external-priority patent/SE9901104D0/xx
Priority claimed from SE9902378A external-priority patent/SE9902378D0/xx
Application filed by Alphahelix Molecular Diagnosti filed Critical Alphahelix Molecular Diagnosti
Application granted granted Critical
Publication of ATE468175T1 publication Critical patent/ATE468175T1/de

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L7/00—Heating or cooling apparatus; Heat insulating devices
    • B01L7/52—Heating or cooling apparatus; Heat insulating devices with provision for submitting samples to a predetermined sequence of different temperatures, e.g. for treating nucleic acid samples
    • B01L7/525—Heating or cooling apparatus; Heat insulating devices with provision for submitting samples to a predetermined sequence of different temperatures, e.g. for treating nucleic acid samples with physical movement of samples between temperature zones
    • B01L7/5255—Heating or cooling apparatus; Heat insulating devices with provision for submitting samples to a predetermined sequence of different temperatures, e.g. for treating nucleic acid samples with physical movement of samples between temperature zones by moving sample containers
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F29/00—Mixers with rotating receptacles
    • B01F29/15—Use of centrifuges for mixing
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L7/00—Heating or cooling apparatus; Heat insulating devices
    • B01L7/52—Heating or cooling apparatus; Heat insulating devices with provision for submitting samples to a predetermined sequence of different temperatures, e.g. for treating nucleic acid samples
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B04—CENTRIFUGAL APPARATUS OR MACHINES FOR CARRYING-OUT PHYSICAL OR CHEMICAL PROCESSES
    • B04B—CENTRIFUGES
    • B04B15/00—Other accessories for centrifuges
    • B04B15/02—Other accessories for centrifuges for cooling, heating, or heat insulating
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B04—CENTRIFUGAL APPARATUS OR MACHINES FOR CARRYING-OUT PHYSICAL OR CHEMICAL PROCESSES
    • B04B—CENTRIFUGES
    • B04B5/00—Other centrifuges
    • B04B5/04—Radial chamber apparatus for separating predominantly liquid mixtures, e.g. butyrometers
    • B04B5/0407—Radial chamber apparatus for separating predominantly liquid mixtures, e.g. butyrometers for liquids contained in receptacles
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B04—CENTRIFUGAL APPARATUS OR MACHINES FOR CARRYING-OUT PHYSICAL OR CHEMICAL PROCESSES
    • B04B—CENTRIFUGES
    • B04B5/00—Other centrifuges
    • B04B5/04—Radial chamber apparatus for separating predominantly liquid mixtures, e.g. butyrometers
    • B04B5/0407—Radial chamber apparatus for separating predominantly liquid mixtures, e.g. butyrometers for liquids contained in receptacles
    • B04B5/0414—Radial chamber apparatus for separating predominantly liquid mixtures, e.g. butyrometers for liquids contained in receptacles comprising test tubes
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B04—CENTRIFUGAL APPARATUS OR MACHINES FOR CARRYING-OUT PHYSICAL OR CHEMICAL PROCESSES
    • B04B—CENTRIFUGES
    • B04B5/00—Other centrifuges
    • B04B5/04—Radial chamber apparatus for separating predominantly liquid mixtures, e.g. butyrometers
    • B04B5/0407—Radial chamber apparatus for separating predominantly liquid mixtures, e.g. butyrometers for liquids contained in receptacles
    • B04B5/0414—Radial chamber apparatus for separating predominantly liquid mixtures, e.g. butyrometers for liquids contained in receptacles comprising test tubes
    • B04B5/0421—Radial chamber apparatus for separating predominantly liquid mixtures, e.g. butyrometers for liquids contained in receptacles comprising test tubes pivotably mounted
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00—Sampling; Preparing specimens for investigation
    • G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • G01N1/44—Sample treatment involving radiation, e.g. heat
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N2035/00465—Separating and mixing arrangements
    • G01N2035/00495—Centrifuges
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/25—Chemistry: analytical and immunological testing including sample preparation
    • Y10T436/25375—Liberation or purification of sample or separation of material from a sample [e.g., filtering, centrifuging, etc.]

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Clinical Laboratory Science (AREA)
  • Physical Or Chemical Processes And Apparatus (AREA)
  • Automatic Analysis And Handling Materials Therefor (AREA)
  • Centrifugal Separators (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Compositions Of Oxide Ceramics (AREA)
  • Disintegrating Or Milling (AREA)
  • Beans For Foods Or Fodder (AREA)
  • Crushing And Grinding (AREA)
AT00921255T 1999-03-25 2000-03-24 Homogenisierung von kleinvolumigen mischungen durch zentrifugierung und erhitzen ATE468175T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
SE9901104A SE9901104D0 (sv) 1999-03-25 1999-03-25 Device and method for performing chemical reactions involving thermocykling
SE9902378A SE9902378D0 (sv) 1999-06-22 1999-06-22 Device and method for homogenising small-volume chemical reaction mixtures
PCT/SE2000/000586 WO2000058013A1 (en) 1999-03-25 2000-03-24 Homogenising of small-volume mixtures by centrifugation and heating

Publications (1)

Publication Number Publication Date
ATE468175T1 true ATE468175T1 (de) 2010-06-15

Family

ID=26663542

Family Applications (1)

Application Number Title Priority Date Filing Date
AT00921255T ATE468175T1 (de) 1999-03-25 2000-03-24 Homogenisierung von kleinvolumigen mischungen durch zentrifugierung und erhitzen

Country Status (11)

Country Link
US (1) US6783993B1 (de)
EP (1) EP1173284B1 (de)
JP (1) JP4681736B2 (de)
CN (1) CN1125687C (de)
AT (1) ATE468175T1 (de)
AU (1) AU766869B2 (de)
CA (1) CA2366732C (de)
DE (1) DE60044429D1 (de)
ES (1) ES2346128T3 (de)
RU (1) RU2266163C2 (de)
WO (1) WO2000058013A1 (de)

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US6977145B2 (en) * 1999-07-28 2005-12-20 Serono Genetics Institute S.A. Method for carrying out a biochemical protocol in continuous flow in a microreactor
EP1110614A3 (de) * 1999-12-24 2002-02-27 Astrium GmbH Vorrichtung zum Temperieren von Behältern
SE0102219D0 (sv) * 2001-06-21 2001-06-21 Alphahelix Ab Thermocycling device and rotor means therefor
KR100488281B1 (ko) 2001-09-15 2005-05-10 아람 바이오시스템 주식회사 열 대류를 이용한 염기서열 증폭 방법 및 장치
WO2003038127A1 (en) 2001-10-30 2003-05-08 Ahram Biosystems Inc. Method and apparatus for amplification of nucleic acid sequences using immobilized dna polymerase
AU2003227117B2 (en) * 2002-05-01 2009-01-15 Corbett Life Science Pty Ltd Device for the amplification of DNA, comprising a microwave energy source
SE0203413D0 (sv) * 2002-11-19 2002-11-19 Alphahelix Ab Device and rotor means therefor
US20060160687A1 (en) * 2002-11-19 2006-07-20 Mats Malmqvist Method and device for rapid homogenisation and mass transport
AU2002952797A0 (en) * 2002-11-20 2002-12-05 Bio-Molecular Holdings Pty Limited Centrifugal device and method using same
AU2003283064B2 (en) * 2002-11-20 2009-06-04 Qiagen Gmbh Centrifugal device and method for performing binding assays
SE0401145D0 (sv) 2004-04-30 2004-04-30 Mats Malmqvist Continuous flow reaction vessel system
DE102004058247B4 (de) * 2004-12-02 2013-03-14 Thermo Electron Led Gmbh Luftgekühlte Zentrifuge
US7775961B2 (en) * 2006-02-06 2010-08-17 Battelle Energy Alliance, Llc Microwave assisted centrifuge and related methods
JP5381100B2 (ja) * 2007-02-22 2014-01-08 東洋紡株式会社 核酸増幅装置
US20080256845A1 (en) * 2007-04-20 2008-10-23 Meikrantz David H Microwave-enhanced biodiesel method and apparatus
SG10201402188TA (en) * 2007-11-30 2014-06-27 Corbett Res Pty Ltd Thermal cycling device
US9409166B2 (en) * 2007-12-10 2016-08-09 The Trustees Of The University Of Pennsylvania Integrated PCR reactor for cell lysis, nucleic acid isolation and purification, and nucleic acid amplication related applications
EP2107125A1 (de) * 2008-03-31 2009-10-07 Eppendorf Array Technologies SA (EAT) Echtzeit-PCR von Targets auf einem Mikroarray
KR101119955B1 (ko) * 2009-05-11 2012-03-15 주식회사 메디사랑 피브리노겐을 생성하는데 사용되는 항온원심분리기
WO2011042426A1 (en) 2009-10-05 2011-04-14 Alphahelix Molecular Diagnostics Ab (Publ) Multifunctional rotor
EP2524026A4 (de) 2010-01-12 2017-10-18 Ahram Biosystems, Inc. Dreistufige hitzekonvektionsvorrichtung und verwendungen davon
CN104630056B (zh) 2010-01-12 2017-11-07 阿赫姆生物系统公司 两阶段热对流装置及其用途
US9273351B2 (en) 2010-09-24 2016-03-01 Alphahelix Molecular Diagnostics Ab Device and method for conducting direct quantitative real time PCR
CA2839951C (en) * 2011-07-27 2018-11-27 Curetis Ag Apparatus and method for a lysis of a sample, in particular for an automated and/or controlled lysis of a sample
US8596566B2 (en) 2012-01-16 2013-12-03 Yang-Te Hsu Biomedical homogenizing device
WO2013165594A1 (en) 2012-04-30 2013-11-07 Life Technologies Corporation Modules and calibration method for a robotic polynucleotide sample preparation system
FR3000549B1 (fr) * 2012-12-27 2015-04-24 Centre Nat Rech Scient Procede et dispositif pour caracteriser un milieu fluide a l'aide d'un substrat semi-conducteur
WO2014126545A1 (en) * 2013-02-18 2014-08-21 Akman Serhan A centrifuge structured for use in making platelet-rich fibrin
AU2013202805B2 (en) 2013-03-14 2015-07-16 Gen-Probe Incorporated System and method for extending the capabilities of a diagnostic analyzer
CN104338617A (zh) * 2013-08-01 2015-02-11 上海知正离心机有限公司 一种在线监测管式离心机及其分离工艺
CN203862180U (zh) * 2014-05-21 2014-10-08 厦门信道生物技术有限公司 一种标本的混均过滤一体处理机构
ES2871861T3 (es) * 2016-03-10 2021-11-02 Pioneer Hi Bred Int Sistema de amplificación por reacción en cadena de la polimerasa mediada por luz y de detección de productos y métodos de uso
KR102016131B1 (ko) * 2017-04-17 2019-10-21 (주)레보스케치 원심력을 이용한 디지털 pcr 장치 및 방법
GB201806762D0 (en) * 2018-04-25 2018-06-06 Bg Res Ltd Improved processes for performing direct detection
WO2020170772A1 (ja) * 2019-02-21 2020-08-27 株式会社シンキー 遠心機において使用される検出器及び検出システム
US20240165628A1 (en) 2021-03-19 2024-05-23 Bg Research Ltd An apparatus and associated methods for thermal cycling
EP4434636B1 (de) 2023-03-23 2026-04-22 Sigma Laborzentrifugen GmbH Laborzentrifugen-messdummyproduktbaugruppe, messdummyprodukt und laborzentrifuge

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Also Published As

Publication number Publication date
JP2002539937A (ja) 2002-11-26
AU766869B2 (en) 2003-10-23
DE60044429D1 (de) 2010-07-01
RU2266163C2 (ru) 2005-12-20
CA2366732A1 (en) 2000-10-05
ES2346128T3 (es) 2010-10-11
WO2000058013A1 (en) 2000-10-05
CA2366732C (en) 2008-11-18
RU2001128879A (ru) 2003-07-27
EP1173284A1 (de) 2002-01-23
EP1173284B1 (de) 2010-05-19
US6783993B1 (en) 2004-08-31
CN1125687C (zh) 2003-10-29
CN1352576A (zh) 2002-06-05
HK1043749A1 (en) 2002-09-27
JP4681736B2 (ja) 2011-05-11
AU4159100A (en) 2000-10-16

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Legal Events

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