ATE468398T1 - Herstellungsverfahren zur produktion aktiver und löslicher proteine in prokaryonten und polycistronische vektoren dafür - Google Patents

Herstellungsverfahren zur produktion aktiver und löslicher proteine in prokaryonten und polycistronische vektoren dafür

Info

Publication number
ATE468398T1
ATE468398T1 AT04736706T AT04736706T ATE468398T1 AT E468398 T1 ATE468398 T1 AT E468398T1 AT 04736706 T AT04736706 T AT 04736706T AT 04736706 T AT04736706 T AT 04736706T AT E468398 T1 ATE468398 T1 AT E468398T1
Authority
AT
Austria
Prior art keywords
active
prokaryonts
production
manufacturing process
soluble proteins
Prior art date
Application number
AT04736706T
Other languages
English (en)
Inventor
Bong Yong Lee
S K - Park
Shin Hye Park
Oh Byung - Kwon
Chae Ha Yoon
Young Ju Kim
Song Young Kim
Kyung Hyun Min
Yoon Seok Lee
Tae Hee Lee
Tai Young Koo
Original Assignee
Daewoong Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Daewoong Co Ltd filed Critical Daewoong Co Ltd
Application granted granted Critical
Publication of ATE468398T1 publication Critical patent/ATE468398T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/70—Vectors or expression systems specially adapted for E. coli
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00—Preparation of peptides or proteins
    • C12P21/02—Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Plant Pathology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
AT04736706T 2004-05-06 2004-06-11 Herstellungsverfahren zur produktion aktiver und löslicher proteine in prokaryonten und polycistronische vektoren dafür ATE468398T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
KR1020040031977A KR100484653B1 (ko) 2004-05-06 2004-05-06 원핵세포에서 활성형의 가용성 단백질을 제조하는 방법 및 이를 위한 폴리시스트론 벡터
PCT/KR2004/001393 WO2005108585A1 (en) 2004-05-06 2004-06-11 Preparation method for the production of active and soluble proteins in prokaryotes and polycistronic vectors therefor

Publications (1)

Publication Number Publication Date
ATE468398T1 true ATE468398T1 (de) 2010-06-15

Family

ID=35320239

Family Applications (1)

Application Number Title Priority Date Filing Date
AT04736706T ATE468398T1 (de) 2004-05-06 2004-06-11 Herstellungsverfahren zur produktion aktiver und löslicher proteine in prokaryonten und polycistronische vektoren dafür

Country Status (8)

Country Link
US (1) US7811786B1 (de)
EP (1) EP1747274B9 (de)
JP (1) JP4510884B2 (de)
KR (1) KR100484653B1 (de)
CN (1) CN101023174B (de)
AT (1) ATE468398T1 (de)
DE (1) DE602004027310D1 (de)
WO (1) WO2005108585A1 (de)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101595228A (zh) 2005-07-21 2009-12-02 艾博特公司 包括sorf构建体的多基因表达和使用多蛋白、前体蛋白和蛋白酶解的方法
DK3399025T3 (da) 2007-03-23 2025-06-16 Wisconsin Alumni Res Found Omprogrammering af somatiske celler
ES2587395T3 (es) 2008-06-04 2016-10-24 Cellular Dynamics International, Inc. Procedimientos para la producción de células IPS usando un enfoque no vírico
WO2010019569A1 (en) 2008-08-12 2010-02-18 Cellular Dynamics International. Inc. Methods for the production of ips cells
JP2013511261A (ja) * 2009-11-18 2013-04-04 マリー ゴールバーン シーオー−オペレイティブ シーオー．リミテッド 組換え微生物
GB201018664D0 (en) * 2010-11-05 2010-12-22 Msd Biolog Uk Ltd Expression process
CN102329811B (zh) * 2011-09-15 2014-08-13 生工生物工程（上海）股份有限公司 一种氨苄青霉素抗性质粒载体及其制备与应用
HUP1200171A1 (hu) * 2012-03-19 2013-09-30 Richter Gedeon Nyrt Módszerek polipeptidek elõállítására
KR101477235B1 (ko) 2012-09-28 2015-01-02 선문대학교 산학협력단 합성생물학에서 사용되는 멀티-모노시스트로닉 벡터의 제작과 응용
WO2014082080A2 (en) * 2012-11-26 2014-05-30 Callidus Biopharma, Inc. Methods for coupling targeting peptides onto recombinant lysosomal enzymes for improved treatments of lysosomal storage diseases
CN106574273B (zh) 2014-08-28 2021-07-02 合成生物制品有限公司 β-内酰胺酶的基于大肠杆菌的生产
CN104946647A (zh) * 2015-06-08 2015-09-30 南京理工大学 一种莱茵衣藻基因间表达处理元件
CN105420263B (zh) * 2015-12-16 2019-07-26 温州医科大学 重组人成纤维细胞生长因子-17的生产方法
CN106434733B (zh) * 2016-08-01 2019-09-27 江南大学 一种适用于谷氨酸棒杆菌的表达载体及其应用
JP7083124B2 (ja) * 2017-04-25 2022-06-10 国立大学法人弘前大学 ムコン酸産生形質転換微生物及びその利用
JP7044870B2 (ja) * 2017-06-23 2022-03-30 珠海億勝生物製薬有限公司 組み換えヒト塩基性線維芽細胞増殖因子（ｒｈ－ｂＦＧＦ）およびｒｈ－ｂＦＧＦを含有する医薬組成物
WO2018232745A1 (zh) * 2017-06-23 2018-12-27 珠海亿胜生物制药有限公司 生产可溶性重组人碱性成纤维细胞生长因子(rh-bFGF)的方法
KR102440312B1 (ko) * 2020-08-28 2022-09-05 한국해양과학기술원 온도안정성을 향상시킨 fgf7 폴리펩타이드 및 그 용도

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL80511A0 (en) * 1985-11-05 1987-02-27 Genetics Inst Multiply amplifiable vectors for high level expression of exogenous dna
JP2570651B2 (ja) * 1986-10-09 1997-01-08 藤沢薬品工業株式会社 Ｍｅｔ−インスリン様成長因子Ｉの製造方法
US5648254A (en) * 1988-01-15 1997-07-15 Zymogenetics, Inc. Co-expression in eukaryotic cells
AU2660397A (en) 1996-04-05 1997-10-29 Board Of Regents, The University Of Texas System Methods for producing soluble, biologically-active disulfide bond-containing eukaryotic proteins in bacterial cells
KR100203919B1 (ko) 1996-10-04 1999-06-15 신동권 수용성 단백질을 생산하는 새로운 발현 플라스미드
KR100254063B1 (ko) 1997-09-30 2000-04-15 신동권 재조합대장균을이용한재조합단백질의제조방법
JP4038555B2 (ja) 2000-12-26 2008-01-30 積水化学工業株式会社 組み換え蛋白質の生産方法及び融合蛋白質
DK1368483T3 (da) * 2001-03-09 2012-11-05 Genentech Inc Fremgangsmåde til fremstilling af polypeptider
KR20040007892A (ko) 2002-07-11 2004-01-28 주식회사 바이오프로젠 재조합 인간 훼리틴 단백질 및 그 제조방법

Also Published As

Publication number Publication date
EP1747274B1 (de) 2010-05-19
CN101023174B (zh) 2011-03-02
EP1747274B9 (de) 2011-02-02
DE602004027310D1 (de) 2010-07-01
CN101023174A (zh) 2007-08-22
US7811786B1 (en) 2010-10-12
EP1747274A1 (de) 2007-01-31
KR100484653B1 (ko) 2005-04-20
WO2005108585A1 (en) 2005-11-17
JP4510884B2 (ja) 2010-07-28
EP1747274A4 (de) 2007-07-11
JP2007535923A (ja) 2007-12-13

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