ATE468846T1 - Magenresistente pharmazeutische dosierform mit n- (2-(2-phthalimidoethoxy)-acetyl)-l-alanyl-d- glutaminsäure (lk-423) - Google Patents

Magenresistente pharmazeutische dosierform mit n- (2-(2-phthalimidoethoxy)-acetyl)-l-alanyl-d- glutaminsäure (lk-423)

Info

Publication number
ATE468846T1
ATE468846T1 AT05733297T AT05733297T ATE468846T1 AT E468846 T1 ATE468846 T1 AT E468846T1 AT 05733297 T AT05733297 T AT 05733297T AT 05733297 T AT05733297 T AT 05733297T AT E468846 T1 ATE468846 T1 AT E468846T1
Authority
AT
Austria
Prior art keywords
phthalimidoethoxy
alanyl
acetyl
dosage form
pharmaceutical dosage
Prior art date
Application number
AT05733297T
Other languages
English (en)
Inventor
Marija Bogataj
Ales Mrhar
Anton Lavric
Manica Cerne
Doris Tibaut
Anton Stalc
Uros Urleb
Tatjana Mateovic
Greta Cof
Janez Kerk
Rok Dreu
Fumio Yoneda
Shizuko Muraoka
Original Assignee
Lek Pharmaceuticals
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lek Pharmaceuticals filed Critical Lek Pharmaceuticals
Application granted granted Critical
Publication of ATE468846T1 publication Critical patent/ATE468846T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2095—Tabletting processes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
AT05733297T 2004-03-26 2005-03-24 Magenresistente pharmazeutische dosierform mit n- (2-(2-phthalimidoethoxy)-acetyl)-l-alanyl-d- glutaminsäure (lk-423) ATE468846T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
SI200400094 2004-03-26
PCT/EP2005/003175 WO2005092295A1 (en) 2004-03-26 2005-03-24 Gastroresistant pharmaceutical dosage form comprising n-(2-(2-phthalimidoethoxy)-acetyl)-l-alanyl-d-glutamic acid (lk-423)

Publications (1)

Publication Number Publication Date
ATE468846T1 true ATE468846T1 (de) 2010-06-15

Family

ID=34964906

Family Applications (1)

Application Number Title Priority Date Filing Date
AT05733297T ATE468846T1 (de) 2004-03-26 2005-03-24 Magenresistente pharmazeutische dosierform mit n- (2-(2-phthalimidoethoxy)-acetyl)-l-alanyl-d- glutaminsäure (lk-423)

Country Status (15)

Country Link
US (1) US20100183714A1 (de)
EP (1) EP1734933B1 (de)
JP (1) JP2007530492A (de)
CN (1) CN1956707B (de)
AR (1) AR048342A1 (de)
AT (1) ATE468846T1 (de)
AU (1) AU2005226927B2 (de)
BR (1) BRPI0509271A (de)
CA (1) CA2559685A1 (de)
DE (1) DE602005021475D1 (de)
MY (1) MY145329A (de)
PE (1) PE20051163A1 (de)
RU (1) RU2375047C2 (de)
TW (1) TW200600121A (de)
WO (1) WO2005092295A1 (de)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2008059062A1 (en) * 2006-11-17 2008-05-22 Da Volterra Colonic delivery using zn/pectin beads with a eudragit coating.
US8273376B2 (en) 2006-11-17 2012-09-25 Da Volterra Colonic delivery of metallo-dependent enzymes
US20100239682A1 (en) * 2007-09-17 2010-09-23 Antoine Andremont Colonic delivery of antimicrobial agents
ES2627745T3 (es) * 2008-11-13 2017-07-31 Nogra Pharma Limited Composiciones antisentido, y procedimientos de fabricación y uso de las mismas
AU2016271303C1 (en) * 2015-06-01 2022-04-14 Xeno Biosciences Inc. Methods and compositions to modulate the gut microbiota and to manage weight
CN109562158A (zh) * 2016-06-23 2019-04-02 纽特莱特公司 在动物中促进生长和提高饲料转化率的方法
EP3538659A4 (de) * 2016-11-09 2020-07-15 Engene, Inc. Intestinale expression von programmiertem zelltod-ligand 1
CN116712540A (zh) * 2016-12-14 2023-09-08 比奥拉治疗股份有限公司 使用整联蛋白抑制剂治疗胃肠道疾病
AU2017378393B2 (en) * 2016-12-14 2023-03-09 Bt Bidco, Inc. Treatment of a disease of the gastrointestinal tract with a TNF inhibitor
CA3045666A1 (en) 2016-12-14 2018-06-21 Progenity, Inc. Treatment of a disease of the gastrointestinal tract with a jak inhibitor and devices
CN108968074B (zh) * 2018-06-06 2021-09-28 福建省农业科学院农业工程技术研究所 一种结肠靶向递送的银耳糖醛酸多糖-芙蓉李花青素复合物及其制备方法
KR102104507B1 (ko) * 2019-08-23 2020-04-24 브릿지바이오테라퓨틱스(주) 팔미토일-l-프롤릴-l-프롤릴-글리실-l-타이로신 나트륨을 포함하는 약제학적 제제 및 이의 제조방법
CN115605226A (zh) 2020-03-26 2023-01-13 纽特莱特公司（Us） 具有抗炎和生长促进活性的去乙酰基葡糖胺胞壁酰二肽的亲脂对映异构体

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2048133T3 (es) * 1990-05-04 2000-01-16 Perio Prod Ltd Sistema de descarga de farmacos para el colon.
JP2773959B2 (ja) * 1990-07-10 1998-07-09 信越化学工業株式会社 大腸内放出性固形製剤
SI9011830B (sl) * 1990-09-27 1999-12-31 Univerza V Ljubljani, Fakulteta Za Farmacijo Novi N-acildipeptidi, postopki za njihovo pripravo in farmacevtski pripravki, ki jih vsebujejo
DE19732903A1 (de) * 1997-07-30 1999-02-04 Falk Pharma Gmbh Pellet-Formulierung zur Behandlung des Intestinaltraktes
UA73092C2 (uk) * 1998-07-17 2005-06-15 Брістол-Майерс Сквібб Компані Таблетка з ентеросолюбільним покриттям і спосіб її приготування
US6627223B2 (en) * 2000-02-11 2003-09-30 Eurand Pharmaceuticals Ltd. Timed pulsatile drug delivery systems

Also Published As

Publication number Publication date
CA2559685A1 (en) 2005-10-06
CN1956707B (zh) 2010-12-29
DE602005021475D1 (de) 2010-07-08
WO2005092295A1 (en) 2005-10-06
AU2005226927B2 (en) 2010-09-23
RU2375047C2 (ru) 2009-12-10
EP1734933A1 (de) 2006-12-27
RU2006137660A (ru) 2008-05-10
TW200600121A (en) 2006-01-01
JP2007530492A (ja) 2007-11-01
CN1956707A (zh) 2007-05-02
BRPI0509271A (pt) 2007-09-04
PE20051163A1 (es) 2006-02-21
EP1734933B1 (de) 2010-05-26
MY145329A (en) 2012-01-31
AR048342A1 (es) 2006-04-19
US20100183714A1 (en) 2010-07-22
AU2005226927A1 (en) 2005-10-06

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