ATE469134T1 - Pharmazeutisch aktive diazepane - Google Patents

Pharmazeutisch aktive diazepane

Info

Publication number
ATE469134T1
ATE469134T1 AT06742609T AT06742609T ATE469134T1 AT E469134 T1 ATE469134 T1 AT E469134T1 AT 06742609 T AT06742609 T AT 06742609T AT 06742609 T AT06742609 T AT 06742609T AT E469134 T1 ATE469134 T1 AT E469134T1
Authority
AT
Austria
Prior art keywords
pharmaceutically active
diazepanes
lfa
activity
active diazepanes
Prior art date
Application number
AT06742609T
Other languages
English (en)
Inventor
Berndt Oberhauser
Dieter Scholz
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis Ag filed Critical Novartis Ag
Application granted granted Critical
Publication of ATE469134T1 publication Critical patent/ATE469134T1/de

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D243/00—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
    • C07D243/06—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
    • C07D243/08—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 not condensed with other rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
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    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A61K31/551—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having two nitrogen atoms, e.g. dilazep
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    • C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links

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  • Health & Medical Sciences (AREA)
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  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
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  • Neurology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Rheumatology (AREA)
  • Diabetes (AREA)
  • Oncology (AREA)
  • Pain & Pain Management (AREA)
  • Immunology (AREA)
  • Pulmonology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Dermatology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Endocrinology (AREA)
  • Hematology (AREA)
  • Communicable Diseases (AREA)
  • Urology & Nephrology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Psychology (AREA)
  • Cardiology (AREA)
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  • Vascular Medicine (AREA)
  • Virology (AREA)
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AT06742609T 2005-04-19 2006-04-19 Pharmazeutisch aktive diazepane ATE469134T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB0507918.1A GB0507918D0 (en) 2005-04-19 2005-04-19 Organic compounds
PCT/EP2006/003583 WO2006111371A1 (en) 2005-04-19 2006-04-19 Pharmaceutically active diazepanes

Publications (1)

Publication Number Publication Date
ATE469134T1 true ATE469134T1 (de) 2010-06-15

Family

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Family Applications (1)

Application Number Title Priority Date Filing Date
AT06742609T ATE469134T1 (de) 2005-04-19 2006-04-19 Pharmazeutisch aktive diazepane

Country Status (17)

Country Link
US (1) US20080300237A1 (de)
EP (2) EP2206704A1 (de)
JP (1) JP2008538357A (de)
KR (2) KR20070121768A (de)
CN (1) CN101163685A (de)
AT (1) ATE469134T1 (de)
AU (1) AU2006237177A1 (de)
BR (1) BRPI0610856A2 (de)
CA (1) CA2600774A1 (de)
DE (1) DE602006014530D1 (de)
ES (1) ES2345628T3 (de)
GB (1) GB0507918D0 (de)
MX (1) MX2007013007A (de)
PL (1) PL1874739T3 (de)
PT (1) PT1874739E (de)
RU (1) RU2007142498A (de)
WO (1) WO2006111371A1 (de)

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AU2016274175B2 (en) 2015-06-12 2021-02-18 Mackay Medical Foundation The Presbyterian Church In Taiwan Mackay Memorial Hospital Methods and polypeptides for modulation of immunoresponse
WO2018106945A1 (en) 2016-12-07 2018-06-14 Progenity Inc. Gastrointestinal tract detection methods, devices and systems
US20200253506A1 (en) 2016-12-14 2020-08-13 Progenity, Inc. Treatment of a disease of the gastrointestinal tract with an integrin inhibitor
CN107759606B (zh) * 2017-11-29 2018-12-21 南京诺希生物科技有限公司 具有抗肿瘤活性的氮杂环烯烃并二氮卓药物分子及其制备方法
US20230033021A1 (en) 2018-06-20 2023-02-02 Progenity, Inc. Treatment of a disease of the gastrointestinal tract with an integrin inhibitor
EP3883635A1 (de) 2018-11-19 2021-09-29 Progenity, Inc. Verfahren und vorrichtungen zur behandlung einer krankheit mit biotherapeutika
CN115666704B (zh) 2019-12-13 2025-09-26 比特比德科有限责任公司 用于将治疗剂递送至胃肠道的可摄取装置

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AU735648B2 (en) 1996-07-12 2001-07-12 Ariad Pharmaceuticals, Inc. Materials and method for treating or preventing pathogenic fungal infection
ATE264863T1 (de) 1999-08-24 2004-05-15 Ariad Gene Therapeutics Inc 28-epirapaloge
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BRPI0610856A2 (pt) 2010-08-03
EP1874739B1 (de) 2010-05-26
DE602006014530D1 (de) 2010-07-08
CA2600774A1 (en) 2006-10-26
EP2206704A1 (de) 2010-07-14
PL1874739T3 (pl) 2010-10-29
US20080300237A1 (en) 2008-12-04
MX2007013007A (es) 2008-01-11
ES2345628T3 (es) 2010-09-28
EP1874739A1 (de) 2008-01-09
AU2006237177A1 (en) 2006-10-26
GB0507918D0 (en) 2005-05-25
WO2006111371A1 (en) 2006-10-26
CN101163685A (zh) 2008-04-16
PT1874739E (pt) 2010-07-27
KR20070121768A (ko) 2007-12-27
KR20100017724A (ko) 2010-02-16
RU2007142498A (ru) 2009-05-27
JP2008538357A (ja) 2008-10-23

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