ATE469223T1 - Pilz transkriptionsaktivator zur verwendung in verfahren zur herstellung von polypeptiden - Google Patents

Pilz transkriptionsaktivator zur verwendung in verfahren zur herstellung von polypeptiden

Info

Publication number
ATE469223T1
ATE469223T1 AT01915099T AT01915099T ATE469223T1 AT E469223 T1 ATE469223 T1 AT E469223T1 AT 01915099 T AT01915099 T AT 01915099T AT 01915099 T AT01915099 T AT 01915099T AT E469223 T1 ATE469223 T1 AT E469223T1
Authority
AT
Austria
Prior art keywords
polypeptides
mushroom
processes
transcription activator
nucleic acid
Prior art date
Application number
AT01915099T
Other languages
English (en)
Inventor
Carsten Hjort
C Hondel
P Punt
F Schuren
Tove Christensen
Original Assignee
Novozymes As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novozymes As filed Critical Novozymes As
Application granted granted Critical
Publication of ATE469223T1 publication Critical patent/ATE469223T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/37—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from fungi
    • C07K14/385—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from fungi from Penicillium
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/37—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from fungi
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/37—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from fungi
    • C07K14/38—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from fungi from Aspergillus

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Mycology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Peptides Or Proteins (AREA)
AT01915099T 2000-03-14 2001-03-14 Pilz transkriptionsaktivator zur verwendung in verfahren zur herstellung von polypeptiden ATE469223T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DKPA200000406 2000-03-14
PCT/DK2001/000169 WO2001068864A1 (en) 2000-03-14 2001-03-14 Fungal transcriptional activator useful in methods for producing polypeptides

Publications (1)

Publication Number Publication Date
ATE469223T1 true ATE469223T1 (de) 2010-06-15

Family

ID=8159325

Family Applications (1)

Application Number Title Priority Date Filing Date
AT01915099T ATE469223T1 (de) 2000-03-14 2001-03-14 Pilz transkriptionsaktivator zur verwendung in verfahren zur herstellung von polypeptiden

Country Status (8)

Country Link
EP (1) EP1266011B1 (de)
JP (1) JP2003526374A (de)
CN (2) CN102174535B (de)
AT (1) ATE469223T1 (de)
AU (1) AU2001242299A1 (de)
DE (1) DE60142226D1 (de)
DK (1) DK1266011T3 (de)
WO (1) WO2001068864A1 (de)

Families Citing this family (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK1613761T3 (da) 2003-03-31 2009-12-14 Novozymes Inc Fremgangsmåder til fremstilling af biologiske stoffer i enzymdefekte mutanter af Aspergillus niger
EP1799827A2 (de) * 2004-10-12 2007-06-27 DSMIP Assets B.V. Bei verfahren zur herstellung eines polypeptids geeignete transkriptionsaktivatoren aus pilzen
DK2410048T3 (en) 2005-01-24 2016-11-28 Dsm Ip Assets Bv A process for the preparation of a compound of interest in a filamentous fungal cell
EP1861421B1 (de) 2005-03-16 2011-10-19 Novozymes Adenium Biotech A/S Rekombinante expression von insekten defensinen in aspergillus
DK1941025T3 (da) 2005-10-17 2011-09-26 Novozymes As Brug af svampemutanter til ekspression af antistoffer
EA014783B1 (ru) * 2005-11-29 2011-02-28 ДСМ АйПи АССЕТС Б.В. Связывающий днк-сайт активатора транскрипции, пригодный для экспрессии генов
CA2657975A1 (en) 2006-06-29 2008-01-03 Dsm Ip Assets B.V. A method for achieving improved polypeptide expression
CN101679993A (zh) 2007-05-09 2010-03-24 诺维信公司 适于选择产生目标多肽的文库克隆的表达克隆方法
CN101182352B (zh) * 2007-11-21 2010-06-09 中国科学院微生物研究所 一种转录激活因子及其编码基因与应用
WO2011009700A1 (en) 2009-07-22 2011-01-27 Dsm Ip Assets B.V. Improved host cell for the production of a compound of interest
CN101906393B (zh) * 2010-06-28 2012-07-25 江南大学 一种谷氨酰胺转胺酶编码基因阻断吸水链霉菌及其应用
CN103443268A (zh) 2011-01-20 2013-12-11 诺维信公司 植物过氧化物酶在丝状真菌中的表达
EP2527448A1 (de) 2011-05-23 2012-11-28 Novozymes A/S Gleichzeitige standortspezifische Integrationen von mehreren Genkopien in faserige Pilze
EP2527432A1 (de) 2011-05-23 2012-11-28 Novozymes A/S Bidirektionaler Cytosin-Deaminase-codierender Selektionsmarker
BR112014016587A2 (pt) 2012-01-05 2020-10-27 Novartis Ag células fúngicas filamentosas deficientes de protease e métodos de uso das mesmas
DK2852610T3 (en) 2012-05-23 2018-09-03 Glykos Finland Oy PRODUCTION OF FUCOSYLED GLYCOPROTEIN
EP3327112B1 (de) 2012-07-19 2020-02-12 DSM IP Assets B.V. Agse-armer stamm
WO2015004241A2 (en) 2013-07-10 2015-01-15 Novartis Ag Multiple proteases deficient filamentous fungal cells and methods of use thereof
AU2015293949B2 (en) 2014-07-21 2019-07-25 Teknologian Tutkimuskeskus Vtt Oy Production of glycoproteins with mammalian-like N-glycans in filamentous fungi
DK3242950T3 (da) 2015-01-06 2021-12-20 Dsm Ip Assets Bv Crispr-cas-system til en trådformet svampeværtscelle
JP6473339B2 (ja) * 2015-02-05 2019-02-20 本田技研工業株式会社 麹菌変異株及び形質転換体
CA2976021A1 (en) 2015-02-20 2016-08-25 Roal Oy Methods for controlling protease production
EP3596199A1 (de) 2017-03-13 2020-01-22 DSM IP Assets B.V. Transkriptioneller regulator-defizienz-stamm mit zweikernigem zink-cluster
WO2018167153A1 (en) 2017-03-17 2018-09-20 Novozymes A/S Improved filamentous fungal host cell
BR112020025589A2 (pt) 2018-06-19 2021-03-23 Dsm Ip Assets B.V. variantes de enzima lipolítica
CA3164414A1 (en) 2020-01-14 2021-07-22 Joyce Josephine Elisabeth ARNOUTS Expression of ovalbumin and its natural variants
EP4525626A1 (de) 2022-05-16 2025-03-26 DSM IP Assets B.V. Varianten eines lipolytischen enzyms
WO2023242273A1 (en) 2022-06-14 2023-12-21 Newmilkbuzz B.V. Expression of milk caseins in filamentous fungi
EP4623075A1 (de) 2022-11-22 2025-10-01 NewMilkBuzz B.V Verbesserte caseinsekretion durch nichtsäugerwirtszellen
WO2024133849A1 (en) 2022-12-22 2024-06-27 The Protein Brewery B.V. Ovalbumin fermentation

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4288627A (en) 1980-02-12 1981-09-08 Phillips Petroleum Company Oxidation of thiols employing cobalt molybdate/triethylamine catalyst
DK122686D0 (da) 1986-03-17 1986-03-17 Novo Industri As Fremstilling af proteiner
CA1333777C (en) 1988-07-01 1995-01-03 Randy M. Berka Aspartic proteinase deficient filamentous fungi
DK0574347T3 (da) 1992-04-15 2004-01-26 Novartis Ag Hidtil ukendt svampeprotease
DK52293D0 (de) 1993-05-05 1993-05-05 Novo Nordisk As
DK76893D0 (de) 1993-06-28 1993-06-28 Novo Nordisk As
CA2191718A1 (en) 1994-06-03 1995-12-14 Randy M. Berka Phosphonyldipeptides useful in the treatment of cardiovascular diseases
CN1253574C (zh) * 1994-06-17 2006-04-26 诺沃奇梅兹有限公司 来自米曲霉的areA基因和其中areA基因已被修饰的真菌
ATE294871T1 (de) 1994-06-30 2005-05-15 Novozymes Biotech Inc Nicht-toxisches, nicht-toxigenes, nicht- pathogenes fusarium expressionssystem und darin zu verwendende promotoren und terminatoren
WO1997012045A1 (en) 1995-09-27 1997-04-03 Chiron Corporation Method of making a protease deficient host
ATE317005T1 (de) 1996-03-27 2006-02-15 Novozymes As Alkaline-phosphatase-defiziente, filamentöse pilze
DE69734449T2 (de) 1996-07-05 2006-08-10 Novozymes A/S Alpha-amylase Transkriptionsfaktor
ATE313620T1 (de) 1996-09-19 2006-01-15 Novozymes As Wirtszellen und methoden für die produktion von proteinen
DE69934596T2 (de) * 1998-10-05 2007-10-04 Novozymes A/S Transkriptionsaktivator prtt aus dem pilz aspergillus niger verwendbar in verfahren zur herstellung von polypeptiden

Also Published As

Publication number Publication date
CN1425068A (zh) 2003-06-18
CN1425068B (zh) 2011-05-18
CN102174535B (zh) 2014-04-09
EP1266011B1 (de) 2010-05-26
WO2001068864A1 (en) 2001-09-20
CN102174535A (zh) 2011-09-07
AU2001242299A1 (en) 2001-09-24
DK1266011T3 (da) 2010-07-26
JP2003526374A (ja) 2003-09-09
DE60142226D1 (de) 2010-07-08
EP1266011A1 (de) 2002-12-18

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