ATE470656T1 - Verfahren zur herstellung von n-acyl-2-amino-4- alkoxy-5-nitrobenzoesäuren - Google Patents
Verfahren zur herstellung von n-acyl-2-amino-4- alkoxy-5-nitrobenzoesäurenInfo
- Publication number
- ATE470656T1 ATE470656T1 AT03713366T AT03713366T ATE470656T1 AT E470656 T1 ATE470656 T1 AT E470656T1 AT 03713366 T AT03713366 T AT 03713366T AT 03713366 T AT03713366 T AT 03713366T AT E470656 T1 ATE470656 T1 AT E470656T1
- Authority
- AT
- Austria
- Prior art keywords
- alkoxy
- acyl
- amino
- producing
- nitrobenzoic acids
- Prior art date
Links
- 238000004519 manufacturing process Methods 0.000 title 1
- CSNNHWWHGAXBCP-UHFFFAOYSA-L Magnesium sulfate Chemical compound [Mg+2].[O-][S+2]([O-])([O-])[O-] CSNNHWWHGAXBCP-UHFFFAOYSA-L 0.000 abstract 2
- JUJWROOIHBZHMG-UHFFFAOYSA-N Pyridine Chemical compound C1=CC=NC=C1 JUJWROOIHBZHMG-UHFFFAOYSA-N 0.000 abstract 2
- 150000003869 acetamides Chemical class 0.000 abstract 1
- 229910052943 magnesium sulfate Inorganic materials 0.000 abstract 1
- 235000019341 magnesium sulphate Nutrition 0.000 abstract 1
- 239000012286 potassium permanganate Substances 0.000 abstract 1
- UMJSCPRVCHMLSP-UHFFFAOYSA-N pyridine Natural products COC1=CC=CN=C1 UMJSCPRVCHMLSP-UHFFFAOYSA-N 0.000 abstract 1
- HXJUTPCZVOIRIF-UHFFFAOYSA-N sulfolane Chemical compound O=S1(=O)CCCC1 HXJUTPCZVOIRIF-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/48—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
- C07D215/54—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3
- C07D215/56—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3 with oxygen atoms in position 4
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C231/00—Preparation of carboxylic acid amides
- C07C231/12—Preparation of carboxylic acid amides by reactions not involving the formation of carboxamide groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/48—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
- C07D215/54—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Quinoline Compounds (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US35477702P | 2002-02-05 | 2002-02-05 | |
| PCT/US2003/003437 WO2003066575A1 (en) | 2002-02-05 | 2003-02-04 | Process for the synthesis of n-acyl-2-amino-4-alkoxy-5-nitrobenzoic acids |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE470656T1 true ATE470656T1 (de) | 2010-06-15 |
Family
ID=27734420
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT03713366T ATE470656T1 (de) | 2002-02-05 | 2003-02-04 | Verfahren zur herstellung von n-acyl-2-amino-4- alkoxy-5-nitrobenzoesäuren |
Country Status (11)
| Country | Link |
|---|---|
| US (2) | US7227037B2 (de) |
| EP (1) | EP1472213B1 (de) |
| JP (1) | JP4361375B2 (de) |
| CN (2) | CN1330627C (de) |
| AT (1) | ATE470656T1 (de) |
| AU (1) | AU2003217323A1 (de) |
| BR (1) | BR0307375A (de) |
| CA (1) | CA2475141A1 (de) |
| DE (1) | DE60332915D1 (de) |
| MX (1) | MXPA04007495A (de) |
| WO (1) | WO2003066575A1 (de) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BR0307375A (pt) * | 2002-02-05 | 2004-12-07 | Wyeth Corp | Processo para a sìntese de ácidos n-acil-2-amino-4-alcóxi-5-nitro-benzóicos |
| CA2529611C (en) | 2002-12-20 | 2009-12-15 | Pfizer Products Inc. | Pyrimidine derivatives for the treatment of abnormal cell growth |
| US7109337B2 (en) | 2002-12-20 | 2006-09-19 | Pfizer Inc | Pyrimidine derivatives for the treatment of abnormal cell growth |
| EP2543376A1 (de) | 2004-04-08 | 2013-01-09 | Targegen, Inc. | Benzotriazin Kinasehemmer |
| BRPI0510963A (pt) | 2004-05-14 | 2007-11-20 | Pfizer Prod Inc | derivados pirimidina para o tratamento do crescimento anormal de células |
| WO2005111024A1 (en) | 2004-05-14 | 2005-11-24 | Pfizer Products Inc. | Pyrimidine derivatives for the treatment of abnormal cell growth |
| MXPA06013164A (es) | 2004-05-14 | 2007-02-13 | Pfizer Prod Inc | Derivados de pirimidina para el tratamiento de crecimiento de celulas anormal. |
| JP2008545688A (ja) * | 2005-05-25 | 2008-12-18 | ワイス | 置換３−シアノキノリン並びにその中間体を合成する方法 |
| CN101180273A (zh) * | 2005-05-25 | 2008-05-14 | 惠氏公司 | 合成6-烷基氨基喹啉衍生物的方法 |
| MX2007014773A (es) * | 2005-05-25 | 2008-02-20 | Wyeth Corp | Metodo para preparar 3-ciano-quinolinas e intermedios hechos de esta forma. |
| NZ567851A (en) | 2005-11-01 | 2011-09-30 | Targegen Inc | Bi-aryl meta-pyrimidine inhibitors of kinases |
| WO2012060847A1 (en) | 2010-11-07 | 2012-05-10 | Targegen, Inc. | Compositions and methods for treating myelofibrosis |
| JP6358419B2 (ja) * | 2013-12-27 | 2018-07-18 | 日産化学工業株式会社 | 脂環式テトラカルボン酸の製造方法 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2138000A1 (en) * | 1994-01-03 | 1995-07-04 | John E. Starrett, Jr. | Retinoid-like compounds |
| US6002008A (en) * | 1997-04-03 | 1999-12-14 | American Cyanamid Company | Substituted 3-cyano quinolines |
| NZ521117A (en) * | 2000-03-13 | 2005-02-25 | Wyeth Corp | Method of treating or inhibiting colonic polyps |
| BR0307375A (pt) * | 2002-02-05 | 2004-12-07 | Wyeth Corp | Processo para a sìntese de ácidos n-acil-2-amino-4-alcóxi-5-nitro-benzóicos |
-
2003
- 2003-02-04 BR BR0307375-0A patent/BR0307375A/pt not_active IP Right Cessation
- 2003-02-04 AT AT03713366T patent/ATE470656T1/de not_active IP Right Cessation
- 2003-02-04 CN CNB038032708A patent/CN1330627C/zh not_active Expired - Fee Related
- 2003-02-04 MX MXPA04007495A patent/MXPA04007495A/es active IP Right Grant
- 2003-02-04 CN CNA2007101042374A patent/CN101050189A/zh active Pending
- 2003-02-04 CA CA002475141A patent/CA2475141A1/en not_active Abandoned
- 2003-02-04 DE DE60332915T patent/DE60332915D1/de not_active Expired - Lifetime
- 2003-02-04 WO PCT/US2003/003437 patent/WO2003066575A1/en not_active Ceased
- 2003-02-04 JP JP2003565950A patent/JP4361375B2/ja not_active Expired - Fee Related
- 2003-02-04 AU AU2003217323A patent/AU2003217323A1/en not_active Abandoned
- 2003-02-04 EP EP03713366A patent/EP1472213B1/de not_active Expired - Lifetime
- 2003-02-05 US US10/358,847 patent/US7227037B2/en not_active Expired - Fee Related
-
2007
- 2007-05-18 US US11/804,509 patent/US7294740B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| JP4361375B2 (ja) | 2009-11-11 |
| EP1472213A1 (de) | 2004-11-03 |
| MXPA04007495A (es) | 2004-11-10 |
| US7227037B2 (en) | 2007-06-05 |
| AU2003217323A1 (en) | 2003-09-02 |
| JP2005517005A (ja) | 2005-06-09 |
| BR0307375A (pt) | 2004-12-07 |
| DE60332915D1 (de) | 2010-07-22 |
| CN101050189A (zh) | 2007-10-10 |
| EP1472213B1 (de) | 2010-06-09 |
| US7294740B2 (en) | 2007-11-13 |
| US20050085662A1 (en) | 2005-04-21 |
| US20070219394A1 (en) | 2007-09-20 |
| CN1628093A (zh) | 2005-06-15 |
| CN1330627C (zh) | 2007-08-08 |
| CA2475141A1 (en) | 2003-08-14 |
| WO2003066575A1 (en) | 2003-08-14 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |