ATE470668T1 - Pyrazolopyrimidine als inhibitoren von cyclinabhängiger kinase zur behandlung von krebs - Google Patents

Pyrazolopyrimidine als inhibitoren von cyclinabhängiger kinase zur behandlung von krebs

Info

Publication number
ATE470668T1
ATE470668T1 AT06816244T AT06816244T ATE470668T1 AT E470668 T1 ATE470668 T1 AT E470668T1 AT 06816244 T AT06816244 T AT 06816244T AT 06816244 T AT06816244 T AT 06816244T AT E470668 T1 ATE470668 T1 AT E470668T1
Authority
AT
Austria
Prior art keywords
compounds
treatment
cyclin
pyrazolopyrimidines
cancer
Prior art date
Application number
AT06816244T
Other languages
English (en)
Inventor
Timothy Guzi
Kamil Paruch
Michael Dwyer
Original Assignee
Schering Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Corp filed Critical Schering Corp
Application granted granted Critical
Publication of ATE470668T1 publication Critical patent/ATE470668T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Rheumatology (AREA)
  • Immunology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Pain & Pain Management (AREA)
  • Hematology (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
AT06816244T 2005-10-06 2006-10-04 Pyrazolopyrimidine als inhibitoren von cyclinabhängiger kinase zur behandlung von krebs ATE470668T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US11/244,772 US7205308B2 (en) 2002-09-04 2005-10-06 Trisubstituted 7-aminopyrazolopyrimidines as cyclin dependent kinase inhibitors
PCT/US2006/038838 WO2007044420A1 (en) 2005-10-06 2006-10-04 Pyrazolopyrimidines as cyclin dependent kinase inhibitors for the treatment of cancer

Publications (1)

Publication Number Publication Date
ATE470668T1 true ATE470668T1 (de) 2010-06-15

Family

ID=37708298

Family Applications (1)

Application Number Title Priority Date Filing Date
AT06816244T ATE470668T1 (de) 2005-10-06 2006-10-04 Pyrazolopyrimidine als inhibitoren von cyclinabhängiger kinase zur behandlung von krebs

Country Status (9)

Country Link
US (1) US7205308B2 (de)
EP (1) EP1934224B1 (de)
JP (1) JP2009511483A (de)
CN (1) CN101321757A (de)
AT (1) ATE470668T1 (de)
CA (1) CA2624822A1 (de)
DE (1) DE602006014848D1 (de)
ES (1) ES2345631T3 (de)
WO (1) WO2007044420A1 (de)

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JP6895963B2 (ja) 2015-11-18 2021-06-30 ジェンザイム・コーポレーション 多発性嚢胞腎のバイオマーカーおよびその使用
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Also Published As

Publication number Publication date
US7205308B2 (en) 2007-04-17
EP1934224B1 (de) 2010-06-09
DE602006014848D1 (de) 2010-07-22
CA2624822A1 (en) 2007-04-19
WO2007044420A1 (en) 2007-04-19
CN101321757A (zh) 2008-12-10
EP1934224A1 (de) 2008-06-25
US20060041131A1 (en) 2006-02-23
ES2345631T3 (es) 2010-09-28
JP2009511483A (ja) 2009-03-19
HK1112233A1 (en) 2008-08-29

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