ATE472611T1 - Verfahren zur diagnose von sepsis durch analyse von cytokine mrna expression - Google Patents
Verfahren zur diagnose von sepsis durch analyse von cytokine mrna expressionInfo
- Publication number
- ATE472611T1 ATE472611T1 AT06809745T AT06809745T ATE472611T1 AT E472611 T1 ATE472611 T1 AT E472611T1 AT 06809745 T AT06809745 T AT 06809745T AT 06809745 T AT06809745 T AT 06809745T AT E472611 T1 ATE472611 T1 AT E472611T1
- Authority
- AT
- Austria
- Prior art keywords
- sepsis
- diagnosis
- mrna expression
- cytokine mrna
- analyzing cytokine
- Prior art date
Links
- 206010040047 Sepsis Diseases 0.000 title abstract 5
- 238000000034 method Methods 0.000 title abstract 3
- 102000004127 Cytokines Human genes 0.000 title 1
- 108090000695 Cytokines Proteins 0.000 title 1
- 238000003745 diagnosis Methods 0.000 title 1
- 108020004999 messenger RNA Proteins 0.000 title 1
- 238000012544 monitoring process Methods 0.000 abstract 2
- 238000003149 assay kit Methods 0.000 abstract 1
- 208000015181 infectious disease Diseases 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/106—Pharmacogenomics, i.e. genetic variability in individual responses to drugs and drug metabolism
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/118—Prognosis of disease development
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/158—Expression markers
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Wood Science & Technology (AREA)
- Analytical Chemistry (AREA)
- Zoology (AREA)
- Genetics & Genomics (AREA)
- Engineering & Computer Science (AREA)
- Pathology (AREA)
- Immunology (AREA)
- Microbiology (AREA)
- Molecular Biology (AREA)
- Biotechnology (AREA)
- Biophysics (AREA)
- Physics & Mathematics (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IE20050783 | 2005-11-25 | ||
| PCT/IE2006/000133 WO2007060647A2 (en) | 2005-11-25 | 2006-11-27 | A method for detecting or monitoring sepsis by analysing cytokine mrna expression levels |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE472611T1 true ATE472611T1 (de) | 2010-07-15 |
Family
ID=37682651
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT06809745T ATE472611T1 (de) | 2005-11-25 | 2006-11-27 | Verfahren zur diagnose von sepsis durch analyse von cytokine mrna expression |
Country Status (6)
| Country | Link |
|---|---|
| US (2) | US20090297474A1 (de) |
| EP (1) | EP1951899B1 (de) |
| AT (1) | ATE472611T1 (de) |
| DE (1) | DE602006015221D1 (de) |
| ES (1) | ES2349691T3 (de) |
| WO (1) | WO2007060647A2 (de) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2740191A1 (en) * | 2008-10-09 | 2010-04-15 | Thomas Ryan | A method of estimating risk of severe sepsis in an individual with infection |
| US10078086B2 (en) * | 2012-08-31 | 2018-09-18 | Childrens Hospital Medical Center | Use of interleukin-27 as a diagnostic biomarker for bacterial infection in critically ill patients |
| AU2014284124B2 (en) | 2013-06-20 | 2020-03-12 | Immunexpress Pty Ltd | Biomarker identification |
| EP3074536B1 (de) | 2013-11-25 | 2019-06-19 | Children's Hospital Medical Center | Biomarkermodell für das risiko einer temporären sepsis im kindesalter |
| JP2017512304A (ja) * | 2014-02-06 | 2017-05-18 | イミューンエクスプレス・プロプライエタリー・リミテッドＩｍｍｕｎｅＸｐｒｅｓｓ Ｐｔｙ Ｌｔｄ | バイオマーカーシグネチャー法ならびにそのための装置およびキット |
| CN109451744B (zh) * | 2016-06-26 | 2022-08-05 | 斯坦福大学托管董事会 | 用于危重患者的死亡预后的生物标志物 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0928293A1 (de) * | 1996-06-20 | 1999-07-14 | Koster, Henk W. | Von il-6 und il-6 rezeptor abgeleitete peptide mit il-6 antagonistischer oder agonistischer aktivität |
| DE10155600B4 (de) * | 2001-11-09 | 2009-08-27 | Oligene Gmbh | Nukleinsäure-Array |
| CA2505843A1 (en) * | 2002-11-12 | 2004-05-27 | Becton, Dickinson And Company | Diagnosis of sepsis or sirs using biomarker profiles |
| MXPA05005073A (es) * | 2002-11-12 | 2005-11-17 | Becton Dickinson Co | Diagnostico de la sepsis o sirs usando perfiles de biomarcadores. |
| FR2855832B1 (fr) * | 2003-06-03 | 2007-09-14 | Biomerieux Sa | Procede de diagnostic et/ou de pronostic d'un syndrome septique |
| GB0426982D0 (en) * | 2004-12-09 | 2005-01-12 | Secr Defence | Early detection of sepsis |
-
2006
- 2006-11-27 ES ES06809745T patent/ES2349691T3/es active Active
- 2006-11-27 WO PCT/IE2006/000133 patent/WO2007060647A2/en not_active Ceased
- 2006-11-27 EP EP06809745A patent/EP1951899B1/de not_active Not-in-force
- 2006-11-27 DE DE602006015221T patent/DE602006015221D1/de active Active
- 2006-11-27 AT AT06809745T patent/ATE472611T1/de not_active IP Right Cessation
- 2006-11-27 US US12/085,450 patent/US20090297474A1/en not_active Abandoned
-
2012
- 2012-10-23 US US13/658,228 patent/US20130040299A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| EP1951899B1 (de) | 2010-06-30 |
| EP1951899A2 (de) | 2008-08-06 |
| ES2349691T3 (es) | 2011-01-10 |
| WO2007060647A2 (en) | 2007-05-31 |
| DE602006015221D1 (de) | 2010-08-12 |
| US20090297474A1 (en) | 2009-12-03 |
| US20130040299A1 (en) | 2013-02-14 |
| WO2007060647A3 (en) | 2007-07-19 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |