ATE533061T1 - Verfahren zur diagnose bakterieller infektionen - Google Patents
Verfahren zur diagnose bakterieller infektionenInfo
- Publication number
- ATE533061T1 ATE533061T1 AT10188288T AT10188288T ATE533061T1 AT E533061 T1 ATE533061 T1 AT E533061T1 AT 10188288 T AT10188288 T AT 10188288T AT 10188288 T AT10188288 T AT 10188288T AT E533061 T1 ATE533061 T1 AT E533061T1
- Authority
- AT
- Austria
- Prior art keywords
- patient
- bacterial infections
- diagnosing bacterial
- risk
- diagnosing
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 2
- 208000035143 Bacterial infection Diseases 0.000 title 1
- 208000022362 bacterial infectious disease Diseases 0.000 title 1
- 108010048233 Procalcitonin Proteins 0.000 abstract 2
- 238000000338 in vitro Methods 0.000 abstract 2
- CWCXERYKLSEGEZ-KDKHKZEGSA-N procalcitonin Chemical compound C([C@@H](C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@H](C(=O)N[C@@H](C)C(=O)N[C@@H]([C@@H](C)CC)C(=O)NCC(=O)N[C@@H](C(C)C)C(=O)NCC(=O)N[C@@H](C)C(=O)N1[C@@H](CCC1)C(=O)NCC(O)=O)[C@@H](C)O)NC(=O)[C@@H](NC(=O)[C@H](CC=1NC=NC=1)NC(=O)[C@H](CC=1C=CC=CC=1)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC=1C=CC=CC=1)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@@H](NC(=O)[C@H](CC=1C=CC(O)=CC=1)NC(=O)[C@@H](NC(=O)CNC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCSC)NC(=O)[C@H]1NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](CO)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(N)=O)NC(=O)CNC(=O)[C@@H](N)CSSC1)[C@@H](C)O)[C@@H](C)O)[C@@H](C)O)C1=CC=CC=C1 CWCXERYKLSEGEZ-KDKHKZEGSA-N 0.000 abstract 2
- 208000031662 Noncommunicable disease Diseases 0.000 abstract 1
- 238000003556 assay Methods 0.000 abstract 1
- 210000001124 body fluid Anatomy 0.000 abstract 1
- 239000010839 body fluid Substances 0.000 abstract 1
- 238000003745 diagnosis Methods 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 238000004393 prognosis Methods 0.000 abstract 1
- 238000013517 stratification Methods 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/02—Local antiseptics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/74—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving hormones or other non-cytokine intercellular protein regulatory factors such as growth factors, including receptors to hormones and growth factors
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/575—Hormones
- G01N2333/585—Calcitonins
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Molecular Biology (AREA)
- Urology & Nephrology (AREA)
- Immunology (AREA)
- Hematology (AREA)
- Biomedical Technology (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Physics & Mathematics (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Biochemistry (AREA)
- Analytical Chemistry (AREA)
- Food Science & Technology (AREA)
- Microbiology (AREA)
- Cell Biology (AREA)
- Biotechnology (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Endocrinology (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP07015271A EP2020603A1 (de) | 2007-08-03 | 2007-08-03 | Verfahren zur Einteilung von Risikoklassen bei stabiler Erkrankung der Koronaraterien |
| EP08152651A EP2101178A1 (de) | 2008-03-12 | 2008-03-12 | Verwendung von Procalcitonin zur Prognose folgender akuter Koronarsyndromen |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE533061T1 true ATE533061T1 (de) | 2011-11-15 |
Family
ID=39745280
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT08786791T ATE514091T1 (de) | 2007-08-03 | 2008-08-01 | Verwendung von procalcitonin (pct) zur risikostratifikation und prognose bei patienten mit einer primären nichtinfektiösen krankheit |
| AT10188288T ATE533061T1 (de) | 2007-08-03 | 2008-08-01 | Verfahren zur diagnose bakterieller infektionen |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT08786791T ATE514091T1 (de) | 2007-08-03 | 2008-08-01 | Verwendung von procalcitonin (pct) zur risikostratifikation und prognose bei patienten mit einer primären nichtinfektiösen krankheit |
Country Status (8)
| Country | Link |
|---|---|
| US (3) | US20110136161A1 (de) |
| EP (4) | EP2301626B1 (de) |
| JP (2) | JP5059943B2 (de) |
| CN (3) | CN103123359B (de) |
| AT (2) | ATE514091T1 (de) |
| DE (1) | DE602008021800C5 (de) |
| ES (3) | ES2377112T3 (de) |
| WO (1) | WO2009019230A2 (de) |
Families Citing this family (47)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103123359B (zh) | 2007-08-03 | 2015-07-29 | B.R.A.H.M.S有限公司 | 降钙素原(pct)在患原发性非传染疾病的患者的风险分级和预后中的应用 |
| HRP20191862T1 (hr) * | 2009-04-14 | 2019-12-27 | B.R.A.H.M.S Gmbh | Procjena rizika u liječenju antibioticima kod pacijenata koji boluju od primarne nezarazne bolesti određivanjem razine prokalcitonina |
| EP2438447B1 (de) * | 2009-06-05 | 2015-02-18 | B.R.A.H.M.S GmbH | Nachweis von bakteriellen Infektionen bei an Dyspnoe leidenden Patienten. |
| CN102472752B (zh) | 2009-08-28 | 2015-08-19 | B.R.A.H.M.S有限公司 | 用于不良事件的预后的降钙素原 |
| JP5722587B2 (ja) * | 2009-10-13 | 2015-05-20 | ベー.エル.アー.ハー.エム.エス ゲゼルシャフト ミット ベシュレンクテル ハフツング | 急性脳卒中または一過性脳虚血発作を有する患者における細菌感染の診断のためのプロカルシトニン及び抗生物質治療のガイダンス |
| JP5798133B2 (ja) * | 2010-03-08 | 2015-10-21 | ベー.エル.アー.ハー.エム.エス ゲゼルシャフト ミット ベシュレンクテル ハフツング | 不特定の愁訴を示す患者における細菌感染及び抗生物質治療の指標を診断するために用いられるプロカルシトニン |
| ITRM20100121A1 (it) * | 2010-03-18 | 2011-09-19 | Univ Pisa | Marcatori molecolari per infezioni delle vie urinarie. |
| CN103119446B (zh) * | 2010-06-18 | 2016-03-30 | B.R.A.H.M.S有限公司 | 预测癌症发生的生物标志物 |
| US20130024205A1 (en) * | 2011-07-18 | 2013-01-24 | International Business Machines Corporation | Dynamically updating electronic medical records and leveraging a person's path in a facility to mitgate risks |
| CN108802385B (zh) | 2012-02-09 | 2022-02-08 | 米密德诊断学有限公司 | 用于诊断感染的标记和决定因素和其使用方法 |
| RU2672561C2 (ru) * | 2012-04-12 | 2018-11-16 | Б.Р.А.Х.М.С Гмбх | Прогнозирование нежелательных явлений у пациентов с предполагаемым диагнозом хронической сердечной недостаточности |
| EP3434260A1 (de) | 2012-05-18 | 2019-01-30 | Critical Care Diagnostics, Inc. | Verfahren zur behandlung oder vorhersage des risikos des ereignisses von ventrikulärer tachyarrhythmie |
| DK2885641T3 (da) | 2012-08-16 | 2018-01-29 | Critical Care Diagnostics Inc | Fremgangsmådeer til forudsigelse af risiko for udvikling af hypertension |
| JP6328655B2 (ja) | 2012-11-15 | 2018-05-23 | オーソ・クリニカル・ダイアグノスティックス・インコーポレーテッド | 反応時間を使用してアッセイを較正すること |
| BR112017002884A2 (pt) | 2014-08-14 | 2018-01-30 | Memed Diagnostics Ltd | ?análise computacional de dados biológicos por meio do uso de variedade e hiperplano? |
| US20170234873A1 (en) | 2014-10-14 | 2017-08-17 | Memed Diagnostics Ltd. | Signatures and determinants for diagnosing infections in non-human subjects and methods of use thereof |
| CN107209184B (zh) | 2014-12-11 | 2020-04-24 | 米密德诊断学有限公司 | 用于诊断多种感染的标记组合及其使用方法 |
| WO2016123163A2 (en) | 2015-01-27 | 2016-08-04 | Kardiatonos, Inc. | Biomarkers of vascular disease |
| US20180224464A1 (en) * | 2015-06-09 | 2018-08-09 | Osaka University | Method of predicting and determining therapeutic effect on rheumatoid arthritis due to biological formulation |
| IL294121B2 (en) | 2016-03-03 | 2023-09-01 | Memed Diagnostics Ltd | An RNA test to diagnose the type of infection |
| EP3423590A4 (de) | 2016-03-03 | 2020-02-26 | Memed Diagnostics Ltd. | Rna-determinanten zur unterscheidung zwischen bakteriellen und viralen infektionen |
| CN106093416B (zh) * | 2016-05-18 | 2018-10-12 | 北京北方生物技术研究所有限公司 | 一种一步法检测降钙素原的试剂盒及其制备方法 |
| CA3027341A1 (en) | 2016-07-10 | 2018-01-18 | Memed Diagnostics Ltd. | Protein signatures for distinguishing between bacterial and viral infections |
| WO2018011796A1 (en) | 2016-07-10 | 2018-01-18 | Memed Diagnostics Ltd. | Early diagnosis of infections |
| WO2018060999A1 (en) * | 2016-09-29 | 2018-04-05 | Memed Diagnostics Ltd. | Methods of risk assessment and disease classification |
| US11385241B2 (en) | 2016-09-29 | 2022-07-12 | Memed Diagnostics Ltd. | Methods of prognosis and treatment |
| CN111094981B (zh) * | 2017-09-13 | 2024-04-16 | B.R.A.H.M.S有限公司 | Pct和pro-adm作为监测抗生素治疗的标记物 |
| CN111656189A (zh) * | 2017-12-20 | 2020-09-11 | B.R.A.H.M.S有限公司 | 基于合并症患者的降钙素原的抗生素疗法指导 |
| US12001939B2 (en) | 2018-12-11 | 2024-06-04 | Eko.Ai Pte. Ltd. | Artificial intelligence (AI)-based guidance for an ultrasound device to improve capture of echo image views |
| US12400762B2 (en) | 2018-12-11 | 2025-08-26 | Eko.Ai Pte. Ltd. | Automatic clinical workflow that recognizes and analyzes 2D and doppler modality echocardiogram images for automated cardiac measurements and diagnosis of cardiac amyloidosis and hypertrophic cardiomyopathy |
| US11446009B2 (en) | 2018-12-11 | 2022-09-20 | Eko.Ai Pte. Ltd. | Clinical workflow to diagnose heart disease based on cardiac biomarker measurements and AI recognition of 2D and doppler modality echocardiogram images |
| US11931207B2 (en) | 2018-12-11 | 2024-03-19 | Eko.Ai Pte. Ltd. | Artificial intelligence (AI) recognition of echocardiogram images to enhance a mobile ultrasound device |
| US12322100B2 (en) | 2018-12-11 | 2025-06-03 | Eko.Ai Pte. Ltd. | Automatic clinical workflow that recognizes and analyzes 2D and doppler modality echocardiogram images for automated cardiac measurements and grading of aortic stenosis severity |
| EP4256330A1 (de) * | 2020-12-02 | 2023-10-11 | Beckman Coulter, Inc. | Nachweis der wahrscheinlichkeit der sepsisentwicklung |
| JP2024516001A (ja) | 2021-04-30 | 2024-04-11 | エフ. ホフマン-ラ ロシュ アーゲー | 敗血症の早期検出のためのesm1マーカーパネル |
| US20240219404A1 (en) | 2021-04-30 | 2024-07-04 | Roche Diagnostics Operations, Inc. | Igfbp7 marker panels for early detection of sepsis |
| CN117242350A (zh) | 2021-04-30 | 2023-12-15 | 豪夫迈·罗氏有限公司 | 用于脓毒症的早期检测的il6标志物组 |
| CN117255948A (zh) | 2021-04-30 | 2023-12-19 | 豪夫迈·罗氏有限公司 | 用于脓毒症的早期检测的pct标志物组 |
| EP4330685A2 (de) | 2021-04-30 | 2024-03-06 | Roche Diagnostics GmbH | Ngal marker panels zur frühen erkennung von sepsis |
| US20240230674A1 (en) | 2021-04-30 | 2024-07-11 | Roche Diagnostics Operations, Inc. | Strem1 marker panels for early detection of sepsis |
| CN117321419A (zh) | 2021-04-30 | 2023-12-29 | 豪夫迈·罗氏有限公司 | 用于脓毒症的早期检测的Presepsin标志物组 |
| US20240230673A1 (en) | 2021-04-30 | 2024-07-11 | Roche Diagnostics Operations, Inc. | Gdf15 marker panels for early detection of sepsis |
| WO2022229440A2 (en) | 2021-04-30 | 2022-11-03 | F. Hoffmann-La Roche Ag | Sflt1 marker panels for early detection of sepsis |
| JP2024537774A (ja) | 2021-09-29 | 2024-10-16 | エフ. ホフマン-ラ ロシュ アーゲー | 敗血症の早期検出のためのMR-proADMマーカーパネル |
| EP4483186A1 (de) | 2022-02-21 | 2025-01-01 | F. Hoffmann-La Roche AG | Dll1-markertafeln für den frühen nachweis von sepsis |
| EP4357778A1 (de) | 2022-10-20 | 2024-04-24 | Heraeus Medical GmbH | Behandlung von mikrobiellen infektionen mit diagnose durch biomarker d-lactat |
| CN119306832B (zh) * | 2023-07-11 | 2025-08-08 | 东莞市朋志生物科技有限公司 | 抗降钙素原抗体、检测降钙素原的试剂和试剂盒 |
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| EP2020603A1 (de) | 2007-08-03 | 2009-02-04 | BRAHMS Aktiengesellschaft | Verfahren zur Einteilung von Risikoklassen bei stabiler Erkrankung der Koronaraterien |
| CN103123359B (zh) | 2007-08-03 | 2015-07-29 | B.R.A.H.M.S有限公司 | 降钙素原(pct)在患原发性非传染疾病的患者的风险分级和预后中的应用 |
| DE102008037108A1 (de) | 2008-08-08 | 2010-02-11 | Samson Aktiengesellschaft | System zum Stellen eines Stellorgans |
| JP5722587B2 (ja) * | 2009-10-13 | 2015-05-20 | ベー.エル.アー.ハー.エム.エス ゲゼルシャフト ミット ベシュレンクテル ハフツング | 急性脳卒中または一過性脳虚血発作を有する患者における細菌感染の診断のためのプロカルシトニン及び抗生物質治療のガイダンス |
| US20110263438A1 (en) | 2010-04-22 | 2011-10-27 | Mehmet Ali Soylemez | Diagnosis and complication risk assessment of pancreatic diabetes using procalcitonin |
-
2008
- 2008-08-01 CN CN201210451017.XA patent/CN103123359B/zh active Active
- 2008-08-01 CN CN201910283751.1A patent/CN110346577A/zh active Pending
- 2008-08-01 ES ES10188288T patent/ES2377112T3/es active Active
- 2008-08-01 WO PCT/EP2008/060176 patent/WO2009019230A2/en not_active Ceased
- 2008-08-01 EP EP10188287A patent/EP2301626B1/de active Active
- 2008-08-01 US US12/671,702 patent/US20110136161A1/en not_active Abandoned
- 2008-08-01 ES ES10188289T patent/ES2401703T3/es active Active
- 2008-08-01 EP EP10188288A patent/EP2293078B1/de active Active
- 2008-08-01 DE DE602008021800.7A patent/DE602008021800C5/de active Active
- 2008-08-01 AT AT08786791T patent/ATE514091T1/de active
- 2008-08-01 CN CN200880101846A patent/CN101790687A/zh active Pending
- 2008-08-01 ES ES10188287T patent/ES2403310T3/es active Active
- 2008-08-01 JP JP2010518695A patent/JP5059943B2/ja active Active
- 2008-08-01 AT AT10188288T patent/ATE533061T1/de active
- 2008-08-01 EP EP10188289A patent/EP2293076B1/de active Active
- 2008-08-01 EP EP08786791A patent/EP2174143B1/de active Active
-
2011
- 2011-02-25 US US13/034,752 patent/US10456364B2/en active Active
-
2012
- 2012-08-02 JP JP2012171897A patent/JP5185460B2/ja active Active
-
2019
- 2019-03-29 US US16/369,966 patent/US11241395B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| EP2293078A2 (de) | 2011-03-09 |
| WO2009019230A2 (en) | 2009-02-12 |
| US20190224135A1 (en) | 2019-07-25 |
| JP5059943B2 (ja) | 2012-10-31 |
| CN101790687A (zh) | 2010-07-28 |
| CN110346577A (zh) | 2019-10-18 |
| JP5185460B2 (ja) | 2013-04-17 |
| EP2293078A3 (de) | 2011-04-06 |
| US11241395B2 (en) | 2022-02-08 |
| US10456364B2 (en) | 2019-10-29 |
| EP2174143A2 (de) | 2010-04-14 |
| EP2301626B1 (de) | 2013-01-16 |
| ES2403310T3 (es) | 2013-05-17 |
| CN103123359A (zh) | 2013-05-29 |
| ES2377112T3 (es) | 2012-03-22 |
| EP2293076A2 (de) | 2011-03-09 |
| JP2012237760A (ja) | 2012-12-06 |
| US20110136161A1 (en) | 2011-06-09 |
| US20110152170A1 (en) | 2011-06-23 |
| WO2009019230A3 (en) | 2009-04-23 |
| EP2293078B1 (de) | 2011-11-09 |
| ATE514091T1 (de) | 2011-07-15 |
| CN103123359B (zh) | 2015-07-29 |
| EP2293076A3 (de) | 2011-03-30 |
| ES2401703T3 (es) | 2013-04-23 |
| EP2301626A3 (de) | 2011-11-16 |
| EP2293076B1 (de) | 2012-12-19 |
| EP2174143B1 (de) | 2011-06-22 |
| HK1183707A1 (en) | 2014-01-03 |
| JP2010536012A (ja) | 2010-11-25 |
| WO2009019230A4 (en) | 2009-06-25 |
| EP2301626A2 (de) | 2011-03-30 |
| DE602008021800C5 (de) | 2022-05-05 |
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