ATE533061T1 - Verfahren zur diagnose bakterieller infektionen - Google Patents
Verfahren zur diagnose bakterieller infektionenInfo
- Publication number
- ATE533061T1 ATE533061T1 AT10188288T AT10188288T ATE533061T1 AT E533061 T1 ATE533061 T1 AT E533061T1 AT 10188288 T AT10188288 T AT 10188288T AT 10188288 T AT10188288 T AT 10188288T AT E533061 T1 ATE533061 T1 AT E533061T1
- Authority
- AT
- Austria
- Prior art keywords
- patient
- bacterial infections
- diagnosing bacterial
- risk
- diagnosing
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 2
- 208000035143 Bacterial infection Diseases 0.000 title 1
- 208000022362 bacterial infectious disease Diseases 0.000 title 1
- 108010048233 Procalcitonin Proteins 0.000 abstract 2
- 238000000338 in vitro Methods 0.000 abstract 2
- CWCXERYKLSEGEZ-KDKHKZEGSA-N procalcitonin Chemical compound C([C@@H](C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@H](C(=O)N[C@@H](C)C(=O)N[C@@H]([C@@H](C)CC)C(=O)NCC(=O)N[C@@H](C(C)C)C(=O)NCC(=O)N[C@@H](C)C(=O)N1[C@@H](CCC1)C(=O)NCC(O)=O)[C@@H](C)O)NC(=O)[C@@H](NC(=O)[C@H](CC=1NC=NC=1)NC(=O)[C@H](CC=1C=CC=CC=1)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC=1C=CC=CC=1)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@@H](NC(=O)[C@H](CC=1C=CC(O)=CC=1)NC(=O)[C@@H](NC(=O)CNC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCSC)NC(=O)[C@H]1NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](CO)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(N)=O)NC(=O)CNC(=O)[C@@H](N)CSSC1)[C@@H](C)O)[C@@H](C)O)[C@@H](C)O)C1=CC=CC=C1 CWCXERYKLSEGEZ-KDKHKZEGSA-N 0.000 abstract 2
- 208000031662 Noncommunicable disease Diseases 0.000 abstract 1
- 238000003556 assay Methods 0.000 abstract 1
- 210000001124 body fluid Anatomy 0.000 abstract 1
- 239000010839 body fluid Substances 0.000 abstract 1
- 238000003745 diagnosis Methods 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 238000004393 prognosis Methods 0.000 abstract 1
- 238000013517 stratification Methods 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/02—Local antiseptics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/74—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving hormones or other non-cytokine intercellular protein regulatory factors such as growth factors, including receptors to hormones and growth factors
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/575—Hormones
- G01N2333/585—Calcitonins
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Molecular Biology (AREA)
- Urology & Nephrology (AREA)
- Immunology (AREA)
- Hematology (AREA)
- Biomedical Technology (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Physics & Mathematics (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Biochemistry (AREA)
- Analytical Chemistry (AREA)
- Food Science & Technology (AREA)
- Microbiology (AREA)
- Cell Biology (AREA)
- Biotechnology (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Endocrinology (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP07015271A EP2020603A1 (de) | 2007-08-03 | 2007-08-03 | Verfahren zur Einteilung von Risikoklassen bei stabiler Erkrankung der Koronaraterien |
| EP08152651A EP2101178A1 (de) | 2008-03-12 | 2008-03-12 | Verwendung von Procalcitonin zur Prognose folgender akuter Koronarsyndromen |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE533061T1 true ATE533061T1 (de) | 2011-11-15 |
Family
ID=39745280
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT08786791T ATE514091T1 (de) | 2007-08-03 | 2008-08-01 | Verwendung von procalcitonin (pct) zur risikostratifikation und prognose bei patienten mit einer primären nichtinfektiösen krankheit |
| AT10188288T ATE533061T1 (de) | 2007-08-03 | 2008-08-01 | Verfahren zur diagnose bakterieller infektionen |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT08786791T ATE514091T1 (de) | 2007-08-03 | 2008-08-01 | Verwendung von procalcitonin (pct) zur risikostratifikation und prognose bei patienten mit einer primären nichtinfektiösen krankheit |
Country Status (8)
| Country | Link |
|---|---|
| US (3) | US20110136161A1 (de) |
| EP (4) | EP2174143B1 (de) |
| JP (2) | JP5059943B2 (de) |
| CN (3) | CN110346577A (de) |
| AT (2) | ATE514091T1 (de) |
| DE (1) | DE602008021800C5 (de) |
| ES (3) | ES2401703T3 (de) |
| WO (1) | WO2009019230A2 (de) |
Families Citing this family (47)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2174143B1 (de) | 2007-08-03 | 2011-06-22 | B.R.A.H.M.S GmbH | Verwendung von procalcitonin (pct) zur risikostratifikation und prognose bei patienten mit einer primären nichtinfektiösen krankheit |
| CN105334330A (zh) * | 2009-04-14 | 2016-02-17 | B.R.A.H.M.S有限公司 | 通过测定降钙素原水平对在原发性非感染性疾病患者中的抗生素治疗进行风险评估 |
| WO2010139475A1 (en) * | 2009-06-05 | 2010-12-09 | B.R.A.H.M.S Gmbh | Detection of bacterial infections in subjects suffering from dyspnea |
| WO2011023813A1 (en) | 2009-08-28 | 2011-03-03 | Brahms Gmbh | Procalcitonin for the prognosis of adverse events |
| ES2601104T3 (es) | 2009-10-13 | 2017-02-14 | B.R.A.H.M.S Gmbh | Procalcitonina para el diagnóstico de infecciones bacterianas y la guía del tratamiento antibiótico en pacientes con apoplejía aguda o accidente isquémico transitorio |
| BR112012022509A2 (pt) * | 2010-03-08 | 2017-09-26 | Brahms Gmbh | procalcitonina para o diagnóstico de infecções bacterianas e orientação de tratamento antibiótico em pacientes com queixas não específicas. |
| ITRM20100121A1 (it) * | 2010-03-18 | 2011-09-19 | Univ Pisa | Marcatori molecolari per infezioni delle vie urinarie. |
| US20140051183A1 (en) * | 2010-06-18 | 2014-02-20 | B.R.A.H.M.S Gmbh | Biomarkers for the prediction of incident cancer |
| US20130024205A1 (en) * | 2011-07-18 | 2013-01-24 | International Business Machines Corporation | Dynamically updating electronic medical records and leveraging a person's path in a facility to mitgate risks |
| CA2863819C (en) | 2012-02-09 | 2021-11-23 | Memed Diagnostics Ltd. | Signatures and determinants for diagnosing infections and methods of use thereof |
| JP5945063B2 (ja) * | 2012-04-12 | 2016-07-05 | ベー.エル.アー.ハー.エム.エス ゲゼルシャフト ミット ベシュレンクテル ハフツング | 慢性心不全が疑われる患者における有害事象の予後 |
| HK1208624A1 (en) | 2012-05-18 | 2016-03-11 | Critical Care Diagnostics, Inc. | Methods for treating or predicting risk of a ventricular tachyarrhythmia event |
| SG10201704311VA (en) * | 2012-08-16 | 2017-07-28 | Critical Care Diagnostics Inc | Methods for predicting risk of developing hypertension |
| IN2015DN04062A (de) | 2012-11-15 | 2015-10-09 | Ortho Clinical Diagnostics Inc | |
| US10303846B2 (en) | 2014-08-14 | 2019-05-28 | Memed Diagnostics Ltd. | Computational analysis of biological data using manifold and a hyperplane |
| US20170234873A1 (en) | 2014-10-14 | 2017-08-17 | Memed Diagnostics Ltd. | Signatures and determinants for diagnosing infections in non-human subjects and methods of use thereof |
| US20170269081A1 (en) | 2014-12-11 | 2017-09-21 | Memed Diagnostics Ltd. | Marker combinations for diagnosing infections and methods of use thereof |
| WO2016123163A2 (en) | 2015-01-27 | 2016-08-04 | Kardiatonos, Inc. | Biomarkers of vascular disease |
| JPWO2016199180A1 (ja) * | 2015-06-09 | 2018-04-12 | 国立大学法人大阪大学 | 生物学的製剤による関節リウマチの治療効果の予測判定方法 |
| WO2017149548A1 (en) | 2016-03-03 | 2017-09-08 | Memed Diagnostics Ltd. | Rna determinants for distinguishing between bacterial and viral infections |
| CN108699609A (zh) | 2016-03-03 | 2018-10-23 | 米密德诊断学有限公司 | 分析rna用于诊断感染类型 |
| CN106093416B (zh) * | 2016-05-18 | 2018-10-12 | 北京北方生物技术研究所有限公司 | 一种一步法检测降钙素原的试剂盒及其制备方法 |
| CA3027341A1 (en) | 2016-07-10 | 2018-01-18 | Memed Diagnostics Ltd. | Protein signatures for distinguishing between bacterial and viral infections |
| US11340223B2 (en) | 2016-07-10 | 2022-05-24 | Memed Diagnostics Ltd. | Early diagnosis of infections |
| US11353456B2 (en) | 2016-09-29 | 2022-06-07 | Memed Diagnostics Ltd. | Methods of risk assessment and disease classification for appendicitis |
| EP3519833B1 (de) | 2016-09-29 | 2024-08-14 | MeMed Diagnostics Ltd. | Verfahren zur prognose und behandlung |
| EP4027145A1 (de) * | 2017-09-13 | 2022-07-13 | B.R.A.H.M.S GmbH | Pro-adm zur therapieüberwachung von intensivpatienten |
| JP7444776B2 (ja) * | 2017-12-20 | 2024-03-06 | ベー.エル.アー.ハー.エム.エス ゲゼルシャフト ミット ベシュレンクテル ハフツング | 併存症を有する患者におけるプロカルシトニンに基づく抗生物質療法のガイダンス |
| US11931207B2 (en) | 2018-12-11 | 2024-03-19 | Eko.Ai Pte. Ltd. | Artificial intelligence (AI) recognition of echocardiogram images to enhance a mobile ultrasound device |
| US12400762B2 (en) | 2018-12-11 | 2025-08-26 | Eko.Ai Pte. Ltd. | Automatic clinical workflow that recognizes and analyzes 2D and doppler modality echocardiogram images for automated cardiac measurements and diagnosis of cardiac amyloidosis and hypertrophic cardiomyopathy |
| US11446009B2 (en) | 2018-12-11 | 2022-09-20 | Eko.Ai Pte. Ltd. | Clinical workflow to diagnose heart disease based on cardiac biomarker measurements and AI recognition of 2D and doppler modality echocardiogram images |
| US12001939B2 (en) | 2018-12-11 | 2024-06-04 | Eko.Ai Pte. Ltd. | Artificial intelligence (AI)-based guidance for an ultrasound device to improve capture of echo image views |
| US12322100B2 (en) | 2018-12-11 | 2025-06-03 | Eko.Ai Pte. Ltd. | Automatic clinical workflow that recognizes and analyzes 2D and doppler modality echocardiogram images for automated cardiac measurements and grading of aortic stenosis severity |
| CN116685852A (zh) * | 2020-12-02 | 2023-09-01 | 贝克曼库尔特有限公司 | 使用参数检测医疗状况、严重性、风险和敏度 |
| CN117280218A (zh) | 2021-04-30 | 2023-12-22 | 豪夫迈·罗氏有限公司 | 用于脓毒症的早期检测的strem1标志物组 |
| WO2022229442A2 (en) | 2021-04-30 | 2022-11-03 | F. Hoffmann-La Roche Ag | Presepsin marker panels for early detection of sepsis |
| EP4330679A2 (de) | 2021-04-30 | 2024-03-06 | Roche Diagnostics GmbH | Esm1-markertafeln zur frühen erkennung von sepsis |
| WO2022229415A2 (en) | 2021-04-30 | 2022-11-03 | F. Hoffmann-La Roche Ag | Gdf15 marker panels for early detection of sepsis |
| EP4330688A2 (de) | 2021-04-30 | 2024-03-06 | Roche Diagnostics GmbH | Pct-markerpanels zur früherkennung von sepsis |
| EP4330681A2 (de) | 2021-04-30 | 2024-03-06 | Roche Diagnostics GmbH | Igfbp7-markertafeln zur frühen erkennung von sepsis |
| JP2024516677A (ja) | 2021-04-30 | 2024-04-16 | エフ. ホフマン-ラ ロシュ アーゲー | 敗血症の早期検出用のngalマーカーパネル |
| US20240230675A1 (en) | 2021-04-30 | 2024-07-11 | Roche Diagnostics Operations, Inc. | Sflt1 marker panels for early detection of sepsis |
| CN117242350A (zh) | 2021-04-30 | 2023-12-15 | 豪夫迈·罗氏有限公司 | 用于脓毒症的早期检测的il6标志物组 |
| US20250035629A1 (en) | 2021-09-29 | 2025-01-30 | Roche Diagnostics Operations, Inc. | Mr-proadm marker panels for early detection of sepsis |
| EP4483186A1 (de) | 2022-02-21 | 2025-01-01 | F. Hoffmann-La Roche AG | Dll1-markertafeln für den frühen nachweis von sepsis |
| EP4357778A1 (de) | 2022-10-20 | 2024-04-24 | Heraeus Medical GmbH | Behandlung von mikrobiellen infektionen mit diagnose durch biomarker d-lactat |
| CN119306832B (zh) * | 2023-07-11 | 2025-08-08 | 东莞市朋志生物科技有限公司 | 抗降钙素原抗体、检测降钙素原的试剂和试剂盒 |
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| CN1800384A (zh) * | 2005-11-08 | 2006-07-12 | 浙江大学 | 降钙素原的制备方法 |
| US20070224643A1 (en) | 2006-03-09 | 2007-09-27 | Mcpherson Paul H | Methods and compositions for the diagnosis of diseases of the aorta |
| DE102006046996A1 (de) * | 2006-10-01 | 2008-04-03 | Brahms Aktiengesellschaft | Diagnose von Infektionen oder Entzündungserkrankungen der Atemwege und Lunge assoziiert mit Herzinsuffizienz |
| EP2020603A1 (de) | 2007-08-03 | 2009-02-04 | BRAHMS Aktiengesellschaft | Verfahren zur Einteilung von Risikoklassen bei stabiler Erkrankung der Koronaraterien |
| EP2174143B1 (de) * | 2007-08-03 | 2011-06-22 | B.R.A.H.M.S GmbH | Verwendung von procalcitonin (pct) zur risikostratifikation und prognose bei patienten mit einer primären nichtinfektiösen krankheit |
| DE102008037108A1 (de) | 2008-08-08 | 2010-02-11 | Samson Aktiengesellschaft | System zum Stellen eines Stellorgans |
| ES2601104T3 (es) * | 2009-10-13 | 2017-02-14 | B.R.A.H.M.S Gmbh | Procalcitonina para el diagnóstico de infecciones bacterianas y la guía del tratamiento antibiótico en pacientes con apoplejía aguda o accidente isquémico transitorio |
| US20110263438A1 (en) | 2010-04-22 | 2011-10-27 | Mehmet Ali Soylemez | Diagnosis and complication risk assessment of pancreatic diabetes using procalcitonin |
-
2008
- 2008-08-01 EP EP08786791A patent/EP2174143B1/de active Active
- 2008-08-01 CN CN201910283751.1A patent/CN110346577A/zh active Pending
- 2008-08-01 CN CN201210451017.XA patent/CN103123359B/zh active Active
- 2008-08-01 EP EP10188289A patent/EP2293076B1/de active Active
- 2008-08-01 AT AT08786791T patent/ATE514091T1/de active
- 2008-08-01 US US12/671,702 patent/US20110136161A1/en not_active Abandoned
- 2008-08-01 EP EP10188287A patent/EP2301626B1/de active Active
- 2008-08-01 EP EP10188288A patent/EP2293078B1/de active Active
- 2008-08-01 DE DE602008021800.7A patent/DE602008021800C5/de active Active
- 2008-08-01 CN CN200880101846A patent/CN101790687A/zh active Pending
- 2008-08-01 JP JP2010518695A patent/JP5059943B2/ja active Active
- 2008-08-01 ES ES10188289T patent/ES2401703T3/es active Active
- 2008-08-01 ES ES10188288T patent/ES2377112T3/es active Active
- 2008-08-01 WO PCT/EP2008/060176 patent/WO2009019230A2/en not_active Ceased
- 2008-08-01 AT AT10188288T patent/ATE533061T1/de active
- 2008-08-01 ES ES10188287T patent/ES2403310T3/es active Active
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2011
- 2011-02-25 US US13/034,752 patent/US10456364B2/en active Active
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2012
- 2012-08-02 JP JP2012171897A patent/JP5185460B2/ja active Active
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2019
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Also Published As
| Publication number | Publication date |
|---|---|
| JP5059943B2 (ja) | 2012-10-31 |
| JP2012237760A (ja) | 2012-12-06 |
| EP2293076A2 (de) | 2011-03-09 |
| EP2174143A2 (de) | 2010-04-14 |
| US10456364B2 (en) | 2019-10-29 |
| EP2293078B1 (de) | 2011-11-09 |
| EP2301626B1 (de) | 2013-01-16 |
| ES2403310T3 (es) | 2013-05-17 |
| CN101790687A (zh) | 2010-07-28 |
| ATE514091T1 (de) | 2011-07-15 |
| US20190224135A1 (en) | 2019-07-25 |
| US11241395B2 (en) | 2022-02-08 |
| CN103123359A (zh) | 2013-05-29 |
| JP2010536012A (ja) | 2010-11-25 |
| HK1183707A1 (en) | 2014-01-03 |
| CN110346577A (zh) | 2019-10-18 |
| DE602008021800C5 (de) | 2022-05-05 |
| EP2293076B1 (de) | 2012-12-19 |
| WO2009019230A3 (en) | 2009-04-23 |
| WO2009019230A4 (en) | 2009-06-25 |
| ES2377112T3 (es) | 2012-03-22 |
| EP2293078A2 (de) | 2011-03-09 |
| EP2301626A3 (de) | 2011-11-16 |
| EP2301626A2 (de) | 2011-03-30 |
| EP2174143B1 (de) | 2011-06-22 |
| JP5185460B2 (ja) | 2013-04-17 |
| CN103123359B (zh) | 2015-07-29 |
| EP2293078A3 (de) | 2011-04-06 |
| EP2293076A3 (de) | 2011-03-30 |
| ES2401703T3 (es) | 2013-04-23 |
| WO2009019230A2 (en) | 2009-02-12 |
| US20110152170A1 (en) | 2011-06-23 |
| US20110136161A1 (en) | 2011-06-09 |
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