ATE472998T1 - Kationische liposomale zubereitungen zur behandlung von rheumatoider arthritis - Google Patents

Kationische liposomale zubereitungen zur behandlung von rheumatoider arthritis

Info

Publication number
ATE472998T1
ATE472998T1 AT07725375T AT07725375T ATE472998T1 AT E472998 T1 ATE472998 T1 AT E472998T1 AT 07725375 T AT07725375 T AT 07725375T AT 07725375 T AT07725375 T AT 07725375T AT E472998 T1 ATE472998 T1 AT E472998T1
Authority
AT
Austria
Prior art keywords
treatment
rheumatoid arthritis
liposomal preparations
cationic liposomal
cationic
Prior art date
Application number
AT07725375T
Other languages
English (en)
Inventor
Martin Funk
Brita Schulze
Eric Guenzi
Uwe Michaelis
Hermann Bohnenkamp
Martin Eichhorn
Marcus Schmitt-Sody
Original Assignee
Medigene Ag
Univ Muenchen L Maximilians
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Medigene Ag, Univ Muenchen L Maximilians filed Critical Medigene Ag
Application granted granted Critical
Publication of ATE472998T1 publication Critical patent/ATE472998T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/337—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having four-membered rings, e.g. taxol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
    • A61K9/1271—Non-conventional liposomes, e.g. PEGylated liposomes or liposomes coated or grafted with polymers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Dermatology (AREA)
  • Dispersion Chemistry (AREA)
  • Rheumatology (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Immunology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
AT07725375T 2006-05-18 2007-05-18 Kationische liposomale zubereitungen zur behandlung von rheumatoider arthritis ATE472998T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US80107906P 2006-05-18 2006-05-18
US87932007P 2007-01-09 2007-01-09
PCT/EP2007/004467 WO2007134819A1 (en) 2006-05-18 2007-05-18 Cationic liposomal preparations for the treatment of rheumatoid arthritis

Publications (1)

Publication Number Publication Date
ATE472998T1 true ATE472998T1 (de) 2010-07-15

Family

ID=38512671

Family Applications (1)

Application Number Title Priority Date Filing Date
AT07725375T ATE472998T1 (de) 2006-05-18 2007-05-18 Kationische liposomale zubereitungen zur behandlung von rheumatoider arthritis

Country Status (5)

Country Link
US (1) US20090232731A1 (de)
EP (1) EP2040674B1 (de)
AT (1) ATE472998T1 (de)
DE (1) DE602007007618D1 (de)
WO (1) WO2007134819A1 (de)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20110002851A1 (en) * 2006-11-03 2011-01-06 Medigene Ag Cationic Colloidal Carriers for Delivery of Active Agents to the Blood-Brain Barrier in the Course of Neuroinflammatory Diseases
US9770414B2 (en) * 2010-05-13 2017-09-26 Pacira Pharmaceuticals, Inc. Sustained release formulation of methotrexate as a disease-modifying antirheumatic drug (DMARD) and an anti-cancer agent
JP6194248B2 (ja) 2010-10-28 2017-09-06 パシラ ファーマシューティカルズ インコーポレーテッド 非ステロイド性抗炎症薬の徐放性処方物
EP2638896A1 (de) * 2012-03-14 2013-09-18 Bioneer A/S Kationisches liposomales Arzneimittelabgabesystem für spezifisches Targeting humaner CD14+ Monozyten in Vollblut
BR112015000174A2 (pt) 2012-07-05 2017-06-27 Taiwan Liposome Co Ltd método para o tratamento da artrite
KR102109188B1 (ko) 2013-04-01 2020-05-11 삼성전자주식회사 양이온성 지질을 포함하는 온도민감성 리포좀 및 그의 용도
CN109983013A (zh) 2016-11-18 2019-07-05 帕西拉制药有限公司 美洛昔康锌复合物微粒多囊脂质体制剂及其制备方法
EP3345614A1 (de) * 2017-01-05 2018-07-11 Amrif B.V. Zusammensetzung mit alkalinphosphatase zur verwendung bei der behandlung von arthritiden
EP3962533A4 (de) * 2019-04-30 2023-01-25 The Medical College of Wisconsin, Inc. Plattform zur verabreichung durch das trommelfell und deren verwendungen
CN113616597B (zh) * 2021-08-02 2026-04-07 上海交通大学 一种美洛昔康的注射剂及其制备方法和用途
WO2025034892A2 (en) * 2023-08-07 2025-02-13 The University Of North Carolina At Chapel Hill Ultrasound contrast agent for binding with or adhering to respiratory mucus and methods for using same

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5583153A (en) * 1994-10-06 1996-12-10 Regents Of The University Of California Use of taxol in the treatment of rheumatoid arthritis
WO1999033493A1 (en) * 1997-12-23 1999-07-08 Inex Pharmaceuticals Corporation Polyamide oligomers
GB9808268D0 (en) * 1998-04-17 1998-06-17 Imp College Innovations Ltd Compound
US6852334B1 (en) * 1999-04-20 2005-02-08 The University Of British Columbia Cationic peg-lipids and methods of use
JP2004511426A (ja) * 2000-05-03 2004-04-15 ミュンヘン　バイオテク　アーゲー 活性化血管部位に関連する陽イオン性の診断薬、画像化剤、および治療薬
EP1374864A1 (de) * 2002-06-26 2004-01-02 Munich Biotech AG Amphiphile, Taxane enthaltende Zusammensetzungen
JP2005534718A (ja) * 2002-06-26 2005-11-17 メディゲーネ オンコロギー ゲゼルシャフト ミット ベシュレンクテル ハフツング カチオンキャリヤー系において診断化合物および治療化合物を安定化させる新規方法
WO2005039533A1 (en) * 2003-10-15 2005-05-06 Medigene Ag Method of administering cationic liposomes comprising an active drug
WO2005065721A2 (en) * 2003-12-30 2005-07-21 Board Of Regents, The University Of Texas System Use of an anti-inflammatory compound for the reduction of inflammation secondary to the administration of a lipid-nucleic acid complex

Also Published As

Publication number Publication date
WO2007134819A1 (en) 2007-11-29
DE602007007618D1 (de) 2010-08-19
EP2040674B1 (de) 2010-07-07
EP2040674A1 (de) 2009-04-01
US20090232731A1 (en) 2009-09-17

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