ATE474587T1 - Inhibitoren des hepatitis-c-virus - Google Patents
Inhibitoren des hepatitis-c-virusInfo
- Publication number
- ATE474587T1 ATE474587T1 AT05814026T AT05814026T ATE474587T1 AT E474587 T1 ATE474587 T1 AT E474587T1 AT 05814026 T AT05814026 T AT 05814026T AT 05814026 T AT05814026 T AT 05814026T AT E474587 T1 ATE474587 T1 AT E474587T1
- Authority
- AT
- Austria
- Prior art keywords
- hepatitis
- virus
- present
- methods
- virus inhibitors
- Prior art date
Links
- 241000711549 Hepacivirus C Species 0.000 title abstract 3
- 239000003112 inhibitor Substances 0.000 title 1
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 3
- 238000000034 method Methods 0.000 abstract 2
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 2
- 101800001473 Spike glycoprotein E2 Proteins 0.000 abstract 1
- 108010067390 Viral Proteins Proteins 0.000 abstract 1
- 241000700605 Viruses Species 0.000 abstract 1
- 230000001413 cellular effect Effects 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 208000010710 hepatitis C virus infection Diseases 0.000 abstract 1
- 208000015181 infectious disease Diseases 0.000 abstract 1
- 230000003993 interaction Effects 0.000 abstract 1
- 238000011321 prophylaxis Methods 0.000 abstract 1
- 238000011282 treatment Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/162—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from virus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
- A61K39/29—Hepatitis virus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
- C12N2770/00011—Details
- C12N2770/24011—Flaviviridae
- C12N2770/24211—Hepacivirus, e.g. hepatitis C virus, hepatitis G virus
- C12N2770/24222—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
- C12N2770/00011—Details
- C12N2770/24011—Flaviviridae
- C12N2770/24211—Hepacivirus, e.g. hepatitis C virus, hepatitis G virus
- C12N2770/24234—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Virology (AREA)
- Organic Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Immunology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Mycology (AREA)
- Microbiology (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Engineering & Computer Science (AREA)
- Communicable Diseases (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Oncology (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US61428004P | 2004-09-29 | 2004-09-29 | |
| PCT/US2005/034777 WO2006039326A2 (en) | 2004-09-29 | 2005-09-26 | Inhibitors of hepatitits c virus |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE474587T1 true ATE474587T1 (de) | 2010-08-15 |
Family
ID=36143015
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT05814026T ATE474587T1 (de) | 2004-09-29 | 2005-09-26 | Inhibitoren des hepatitis-c-virus |
Country Status (11)
| Country | Link |
|---|---|
| US (2) | US7381705B2 (de) |
| EP (1) | EP1797112B1 (de) |
| JP (1) | JP4980915B2 (de) |
| AT (1) | ATE474587T1 (de) |
| AU (1) | AU2005292135B2 (de) |
| CA (1) | CA2582095A1 (de) |
| DE (1) | DE602005022463D1 (de) |
| ES (1) | ES2349153T3 (de) |
| PL (1) | PL1797112T3 (de) |
| PT (1) | PT1797112E (de) |
| WO (1) | WO2006039326A2 (de) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2624153A1 (en) * | 2005-09-29 | 2007-04-12 | The Scripps Research Institute | Viral peptides and their use to inhibit viral infections against viruses of the flaviridae family |
| US20100261640A1 (en) | 2007-04-10 | 2010-10-14 | Branco Luis M | Soluble and membrane anchored forms of lassa virus subunit proteins |
| WO2009021063A2 (en) * | 2007-08-06 | 2009-02-12 | The Regents Of The University Of California | Composition and method of use for hcv immunization |
| WO2009030872A1 (de) * | 2007-09-07 | 2009-03-12 | Mats Axel Atterdag Persson | Vorrichtung zum festlegen einer gliedmasse |
| AU2008297927A1 (en) * | 2007-09-11 | 2009-03-19 | Mondobiotech Laboratories Ag | Use of Trp6-Triptorelin and D-Leu6-Leuprolide as therapeutic agents |
| US20100104555A1 (en) * | 2008-10-24 | 2010-04-29 | The Scripps Research Institute | HCV neutralizing epitopes |
| CA2658714A1 (en) | 2009-03-17 | 2010-09-17 | Thomas Krey | Hcv-derived polypeptides and uses thereof |
| ES2698076T3 (es) | 2011-10-07 | 2019-01-30 | Isd Immunotech Aps | Identificación de los dominios inmunosupresores en las proteínas de fusión de los virus de ARN con envoltura |
| CN104324361A (zh) * | 2014-05-16 | 2015-02-04 | 中国疾病预防控制中心病毒病预防控制所 | 丙型肝炎病毒(hcv)细胞进入抑制肽zte2序列及应用 |
| CN109232721B (zh) * | 2018-09-26 | 2021-06-29 | 广州市第八人民医院 | Hcv包膜蛋白高度保守区域的肽段418-429及其用途 |
| CN114630698A (zh) * | 2019-07-26 | 2022-06-14 | 斯克里普斯研究学院 | 经改造hcv e2免疫原和相关疫苗组合物 |
Family Cites Families (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR0185373B1 (ko) * | 1989-03-17 | 1999-05-01 | 로버트 피. 블랙버언 | Hcv 폴리단백질에서 유래되는 hcv 아미노산 서열 부분을 포함하는 폴리펩티드 및 그 사용 |
| US5747239A (en) | 1990-02-16 | 1998-05-05 | United Biomedical, Inc. | Synthetic peptides specific for the detection of antibodies to HCV, diagnosis of HCV infection and preventions thereof as vaccines |
| CA2175692A1 (en) * | 1993-11-04 | 1995-05-11 | Geert Leroux-Roels | Immunodominant human t-cell epitopes of hepatitis c virus |
| US6127116A (en) | 1995-08-29 | 2000-10-03 | Washington University | Functional DNA clone for hepatitis C virus (HCV) and uses thereof |
| SE9503380D0 (sv) * | 1995-09-29 | 1995-09-29 | Pharmacia Ab | Protein derivatives |
| US6037348A (en) | 1996-02-09 | 2000-03-14 | Eli Lilly And Company | Inhibition of viral replication |
| AU726374B2 (en) * | 1997-03-05 | 2000-11-02 | University Of Washington | Novel screening methods to identify agents that selectively inhibit hepatitis C virus replication |
| US6153421A (en) * | 1997-07-18 | 2000-11-28 | The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services | Cloned genomes of infectious hepatitis C viruses and uses thereof |
| US6127166A (en) * | 1997-11-03 | 2000-10-03 | Bayley; Hagan | Molluscan ligament polypeptides and genes encoding them |
| US7091324B2 (en) * | 1998-11-05 | 2006-08-15 | Board Of Trustees Of Leland Stanford Junior University | Prevention and treatment of HCV infection employing antibodies directed against conformational epitopes |
| EP1178116A1 (de) * | 2000-08-03 | 2002-02-06 | Hybrigenics S.A. | Sid nukleische Saüre und aus einem pathogenischen Stamm des Hepatitis C Viruses selektierte Polypeptide und deren Verwendungenthereof |
| KR100801123B1 (ko) * | 2000-08-17 | 2008-02-05 | 트리펩 아베 | 리바비린 함유 백신 및 이것의 사용 방법 |
| US20030232745A1 (en) | 2001-06-26 | 2003-12-18 | Olson William C. | Uses of DC-sign and DC-Signr for inhibiting hepatitis C virus infection |
| US7022323B2 (en) * | 2001-06-26 | 2006-04-04 | Progenics Pharmaceuticals, Inc. | Uses of DC-SIGN and DC-SIGNR for inhibiting hepatitis C virus infection |
| EP2338894A1 (de) | 2002-11-08 | 2011-06-29 | The Administrators of the Tulane Educational Fund | Flavivirusfusionsinhibitoren |
| EP1638993A4 (de) * | 2003-06-10 | 2007-05-09 | Univ Melbourne | Immunmodulierende zusammensetzungen, anwendungen davon und verfahren zu deren herstellung |
-
2005
- 2005-09-26 AT AT05814026T patent/ATE474587T1/de not_active IP Right Cessation
- 2005-09-26 ES ES05814026T patent/ES2349153T3/es active Active
- 2005-09-26 PL PL05814026T patent/PL1797112T3/pl unknown
- 2005-09-26 US US11/235,672 patent/US7381705B2/en not_active Expired - Fee Related
- 2005-09-26 EP EP05814026A patent/EP1797112B1/de not_active Not-in-force
- 2005-09-26 JP JP2007534728A patent/JP4980915B2/ja not_active Expired - Fee Related
- 2005-09-26 PT PT05814026T patent/PT1797112E/pt unknown
- 2005-09-26 WO PCT/US2005/034777 patent/WO2006039326A2/en not_active Ceased
- 2005-09-26 DE DE602005022463T patent/DE602005022463D1/de active Active
- 2005-09-26 AU AU2005292135A patent/AU2005292135B2/en not_active Ceased
- 2005-09-26 CA CA002582095A patent/CA2582095A1/en not_active Abandoned
-
2008
- 2008-05-19 US US12/152,964 patent/US20080241156A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| JP4980915B2 (ja) | 2012-07-18 |
| WO2006039326A2 (en) | 2006-04-13 |
| AU2005292135A1 (en) | 2006-04-13 |
| EP1797112A4 (de) | 2009-04-01 |
| EP1797112A2 (de) | 2007-06-20 |
| WO2006039326A3 (en) | 2007-05-10 |
| EP1797112B1 (de) | 2010-07-21 |
| AU2005292135B2 (en) | 2011-09-29 |
| US20080241156A1 (en) | 2008-10-02 |
| US7381705B2 (en) | 2008-06-03 |
| CA2582095A1 (en) | 2006-04-13 |
| US20060069027A1 (en) | 2006-03-30 |
| DE602005022463D1 (de) | 2010-09-02 |
| PL1797112T3 (pl) | 2011-04-29 |
| JP2008514717A (ja) | 2008-05-08 |
| ES2349153T3 (es) | 2010-12-28 |
| PT1797112E (pt) | 2010-10-25 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |