ATE476450T1 - Vernetzte polysaccharidzusammensetzung - Google Patents

Vernetzte polysaccharidzusammensetzung

Info

Publication number
ATE476450T1
ATE476450T1 AT04727786T AT04727786T ATE476450T1 AT E476450 T1 ATE476450 T1 AT E476450T1 AT 04727786 T AT04727786 T AT 04727786T AT 04727786 T AT04727786 T AT 04727786T AT E476450 T1 ATE476450 T1 AT E476450T1
Authority
AT
Austria
Prior art keywords
cross
linked polysaccharide
polysaccharide composition
gels
linked
Prior art date
Application number
AT04727786T
Other languages
English (en)
Inventor
Simone Vonwiller
Geoffrey Heber
Original Assignee
Ultraceuticals R & D Pty Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ultraceuticals R & D Pty Ltd filed Critical Ultraceuticals R & D Pty Ltd
Application granted granted Critical
Publication of ATE476450T1 publication Critical patent/ATE476450T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/0006—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid
    • C08B37/0024—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid beta-D-Glucans; (beta-1,3)-D-Glucans, e.g. paramylon, coriolan, sclerotan, pachyman, callose, scleroglucan, schizophyllan, laminaran, lentinan or curdlan; (beta-1,6)-D-Glucans, e.g. pustulan; (beta-1,4)-D-Glucans; (beta-1,3)(beta-1,4)-D-Glucans, e.g. lichenan; Derivatives thereof
    • C08B37/0027—2-Acetamido-2-deoxy-beta-glucans; Derivatives thereof
    • C08B37/003—Chitin, i.e. 2-acetamido-2-deoxy-(beta-1,4)-D-glucan or N-acetyl-beta-1,4-D-glucosamine; Chitosan, i.e. deacetylated product of chitin or (beta-1,4)-D-glucosamine; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/738—Cross-linked polysaccharides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/006—Heteroglycans, i.e. polysaccharides having more than one sugar residue in the main chain in either alternating or less regular sequence; Gellans; Succinoglycans; Arabinogalactans; Tragacanth or gum tragacanth or traganth from Astragalus; Gum Karaya from Sterculia urens; Gum Ghatti from Anogeissus latifolia; Derivatives thereof
    • C08B37/0063—Glycosaminoglycans or mucopolysaccharides, e.g. keratan sulfate; Derivatives thereof, e.g. fucoidan
    • C08B37/0072—Hyaluronic acid, i.e. HA or hyaluronan; Derivatives thereof, e.g. crosslinked hyaluronic acid (hylan) or hyaluronates

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Biochemistry (AREA)
  • Polymers & Plastics (AREA)
  • Materials Engineering (AREA)
  • Immunology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Inorganic Chemistry (AREA)
  • Rheumatology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Dermatology (AREA)
  • Transplantation (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Cosmetics (AREA)
AT04727786T 2003-04-17 2004-04-16 Vernetzte polysaccharidzusammensetzung ATE476450T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
AU2003901834A AU2003901834A0 (en) 2003-04-17 2003-04-17 Cross-linked polysaccharide compositions
PCT/AU2004/000509 WO2004092223A1 (en) 2003-04-17 2004-04-16 Cross-linked polysaccharide composition

Publications (1)

Publication Number Publication Date
ATE476450T1 true ATE476450T1 (de) 2010-08-15

Family

ID=31500871

Family Applications (1)

Application Number Title Priority Date Filing Date
AT04727786T ATE476450T1 (de) 2003-04-17 2004-04-16 Vernetzte polysaccharidzusammensetzung

Country Status (13)

Country Link
US (2) US20070026070A1 (de)
EP (1) EP1613663B1 (de)
JP (2) JP2006523731A (de)
KR (1) KR20060008906A (de)
CN (1) CN100509858C (de)
AT (1) ATE476450T1 (de)
AU (1) AU2003901834A0 (de)
BR (1) BRPI0409890A (de)
CA (1) CA2522232C (de)
DE (1) DE602004028455D1 (de)
ES (1) ES2349924T3 (de)
MX (1) MXPA05011098A (de)
WO (1) WO2004092223A1 (de)

Families Citing this family (85)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7090745B2 (en) * 2002-09-13 2006-08-15 University Of Pittsburgh Method for increasing the strength of a cellulosic product
FR2861734B1 (fr) 2003-04-10 2006-04-14 Corneal Ind Reticulation de polysaccharides de faible et forte masse moleculaire; preparation d'hydrogels monophasiques injectables; polysaccharides et hydrogels obtenus
AU2003901834A0 (en) * 2003-04-17 2003-05-01 Clearcoll Pty Ltd Cross-linked polysaccharide compositions
EP1668148B1 (de) 2003-09-04 2008-12-31 Human Genetic Signatures PTY Ltd. Nukleinsäurenachweistest
US8168777B2 (en) 2004-04-29 2012-05-01 Human Genetic Signatures Pty. Ltd. Bisulphite reagent treatment of nucleic acid
WO2005112888A2 (en) * 2004-05-20 2005-12-01 Mentor Corporation Methods for making injectable polymer hydrogels
JP4980219B2 (ja) * 2004-09-10 2012-07-18 ヒューマン ジェネティック シグネチャーズ ピーティーワイ リミテッド インターカレート型擬似ヌクレオチド(ipn)を含有するインターカレーティング核酸(ina)を含む増幅ブロッカー
NZ555620A (en) * 2004-12-03 2008-08-29 Human Genetic Signatures Pty Methods for simplifying microbial nucleic acids by chemical modification of cytosines
EP1883707B1 (de) 2005-05-26 2014-04-09 Human Genetic Signatures PTY Ltd Isothermische strangverdrängungsamplifikation unter verwendung von eine nichtreguläre base enthaltenden primern
CN101292046B (zh) * 2005-09-14 2013-03-13 人类遗传标记控股有限公司 健康状态的测定法
ATE533791T1 (de) * 2005-09-27 2011-12-15 Univ Grenoble 1 Mit einer polymerisierbaren gruppierung funktionalisiertes hydrogel und anwendungen davon als biosensoren oder bioreaktoren
US20080050738A1 (en) * 2006-05-31 2008-02-28 Human Genetic Signatures Pty Ltd. Detection of target nucleic acid
WO2008034176A1 (en) * 2006-09-19 2008-03-27 Ultraceuticals R & D Pty Ltd Cross-linked polysaccharide gels
FR2909560B1 (fr) * 2006-12-06 2012-12-28 Fabre Pierre Dermo Cosmetique Gel d'acide hyaluronique pour injection intradermique
US20100092972A1 (en) * 2007-03-16 2010-04-15 Human Genetic Signatures Pty Ltd. Assay for gene expression
JP2008255061A (ja) * 2007-04-06 2008-10-23 Shiseido Co Ltd 可溶性架橋ヒアルロン酸含有眼用組成物
EP2152743A2 (de) * 2007-05-23 2010-02-17 Allergan, Inc. Quervernetztes collagen und anwendungen davon
US20110077737A1 (en) * 2007-07-30 2011-03-31 Allergan, Inc. Tunably Crosslinked Polysaccharide Compositions
US8318695B2 (en) * 2007-07-30 2012-11-27 Allergan, Inc. Tunably crosslinked polysaccharide compositions
US20120071437A1 (en) * 2007-07-30 2012-03-22 Allergan, Inc. Tunable crosslinked polysaccharide compositions
ES2381417T3 (es) * 2007-09-28 2012-05-28 Shiseido Company, Ltd. Polvo de ácido hialurónico reticulado hinchable y procedimiento para fabricarlo
EP2229175A4 (de) * 2007-10-04 2015-06-17 Ultraceuticals R & D Pty Ltd Zusammensetzung und verfahren zur hautregeneration
US8697044B2 (en) 2007-10-09 2014-04-15 Allergan, Inc. Crossed-linked hyaluronic acid and collagen and uses thereof
EP3498299A1 (de) 2007-11-16 2019-06-19 Aclaris Therapeutics, Inc. Zusammensetzungen und verfahren zur behandlung von purpura
AU2008329549B2 (en) 2007-11-27 2013-08-22 Human Genetic Signatures Pty Ltd Enzymes for amplification and copying bisulphite modified nucleic acids
US20090143348A1 (en) * 2007-11-30 2009-06-04 Ahmet Tezel Polysaccharide gel compositions and methods for sustained delivery of drugs
US8394784B2 (en) * 2007-11-30 2013-03-12 Allergan, Inc. Polysaccharide gel formulation having multi-stage bioactive agent delivery
US8394782B2 (en) * 2007-11-30 2013-03-12 Allergan, Inc. Polysaccharide gel formulation having increased longevity
JP2011505845A (ja) * 2007-12-20 2011-03-03 ヒューマン ジェネティック シグネチャーズ ピーティーワイ リミテッド 核酸増幅に伴う汚染物質の排除
EP2105465A1 (de) * 2008-03-27 2009-09-30 Greene, Tweed Of Delaware, Inc. An ein inertes Substrat gebundene Perfluorelastomer-Bestandteile und zugehörige Verfahren
KR101027630B1 (ko) * 2008-06-18 2011-04-07 주식회사 제네웰 연골 재생용 다공성 히알루론산-콜라겐 천연 고분자 지지체의 제조방법
US8450475B2 (en) 2008-08-04 2013-05-28 Allergan, Inc. Hyaluronic acid-based gels including lidocaine
JP5722217B2 (ja) 2008-09-02 2015-05-20 アラーガン・ホールディングス・フランス・ソシエテ・パール・アクシオン・サンプリフィエAllergan Holdings France S.A.S. ヒアルロン酸および/またはその誘導体の糸、その作製方法、ならびにその使用
NO2236523T3 (de) 2009-03-30 2018-07-21
US9371402B2 (en) 2009-04-09 2016-06-21 Scivision Biotech Inc. Method for producing cross-linked hyaluronic acid
CN101544705B (zh) * 2009-05-04 2011-09-14 西南大学 蔗糖缩水甘油醚交联剂、抗皱整理剂及其合成方法
CA2804973A1 (en) * 2009-07-10 2011-01-13 Milux Holding S.A. Implantable medical device for lubrication of a synovial joint and method for implanting the device
US20110171311A1 (en) * 2010-01-13 2011-07-14 Allergan Industrie, Sas Stable hydrogel compositions including additives
US20110171286A1 (en) * 2010-01-13 2011-07-14 Allergan, Inc. Hyaluronic acid compositions for dermatological use
US20110171310A1 (en) * 2010-01-13 2011-07-14 Allergan Industrie, Sas Hydrogel compositions comprising vasoconstricting and anti-hemorrhagic agents for dermatological use
US9114188B2 (en) 2010-01-13 2015-08-25 Allergan, Industrie, S.A.S. Stable hydrogel compositions including additives
US20110172180A1 (en) 2010-01-13 2011-07-14 Allergan Industrie. Sas Heat stable hyaluronic acid compositions for dermatological use
CA2792729C (en) * 2010-03-12 2016-06-28 Allergan Industrie, Sas Fluid compositions for improving skin conditions
HUE030138T2 (en) 2010-03-22 2017-04-28 Allergan Inc Polysaccharide and protein-polysaccharide cross-linked hydrogels for soft tissue augmentation
CN102933615B (zh) * 2010-06-08 2015-08-12 陶氏环球技术有限责任公司 制备粒状可逆交联的聚合物材料的方法
ITUD20100112A1 (it) * 2010-06-09 2011-12-10 Farma Derma S R L Preparazione per uso vaginale e rettale e relativo procedimento di produzione
US8883139B2 (en) 2010-08-19 2014-11-11 Allergan Inc. Compositions and soft tissue replacement methods
US9005605B2 (en) 2010-08-19 2015-04-14 Allergan, Inc. Compositions and soft tissue replacement methods
US8889123B2 (en) 2010-08-19 2014-11-18 Allergan, Inc. Compositions and soft tissue replacement methods
US8697057B2 (en) 2010-08-19 2014-04-15 Allergan, Inc. Compositions and soft tissue replacement methods
US20130096081A1 (en) 2011-06-03 2013-04-18 Allergan, Inc. Dermal filler compositions
AU2012262047A1 (en) * 2011-06-03 2014-01-16 Allergan, Inc. Dermal filler compositions including antioxidants
US9408797B2 (en) 2011-06-03 2016-08-09 Allergan, Inc. Dermal filler compositions for fine line treatment
US9393263B2 (en) 2011-06-03 2016-07-19 Allergan, Inc. Dermal filler compositions including antioxidants
US9662422B2 (en) 2011-09-06 2017-05-30 Allergan, Inc. Crosslinked hyaluronic acid-collagen gels for improving tissue graft viability and soft tissue augmentation
US20130244943A1 (en) 2011-09-06 2013-09-19 Allergan, Inc. Hyaluronic acid-collagen matrices for dermal filling and volumizing applications
KR101912488B1 (ko) 2011-09-07 2018-10-26 휴먼 제네틱 시그너처스 피티와이 엘티디 분자 검출 분석법
KR101428145B1 (ko) * 2011-11-24 2014-08-08 (주)아모레퍼시픽 수불용성 겔 조성물 및 그 제조방법
KR101240518B1 (ko) * 2012-03-26 2013-03-11 주식회사 제네웰 생체 적합성 고분자를 이용한 이식용 재료
ITMI20120732A1 (it) 2012-05-03 2013-11-04 B S Srl Polisaccaridi reticolati a memoria di forma
KR101413510B1 (ko) * 2012-06-19 2014-07-02 주식회사 제네웰 생체 적합성 고분자를 이용한 이식용 재료의 제조방법
WO2014039012A1 (en) * 2012-09-06 2014-03-13 Nanyang Technological University Hyaluronic acid-based drug delivery systems
FR3005056B1 (fr) * 2013-04-24 2016-04-01 Ayawane Hydrogel a base de polysaccharides natifs et/ou fonctionnalises, phosphates co-reticules
CA2916330A1 (en) * 2013-06-28 2014-12-31 Galderma S.A. A process for preparing a cross-linked hyaluronic acid product
WO2015109064A1 (en) * 2014-01-17 2015-07-23 E. I. Du Pont De Nemours And Company Production of a solution of cross-linked poly alpha-1,3-glucan and poly alpha-1,3-glucan film made therefrom
WO2016051219A1 (en) 2014-09-30 2016-04-07 Allergan Industrie, Sas Stable hydrogel compositions including additives
CN104387609B (zh) * 2014-11-18 2018-06-01 中国林业科学研究院林产化学工业研究所 一种纤维素多孔吸附材料的制备方法
WO2016128783A1 (en) 2015-02-09 2016-08-18 Allergan Industrie Sas Compositions and methods for improving skin appearance
EP3653232A1 (de) 2015-02-13 2020-05-20 Allergan Industrie, SAS Implantate zur formung, verstärkung oder korrektur von gesichtszügen wie etwa dem kinn
FR3032617B1 (fr) * 2015-02-16 2018-03-16 Kylane Laboratoires Sa Procede de preparation d un hydrogel injectable; hydrogel obtenu; utilisation de l hydrogel obtenu
CN104721873B (zh) * 2015-03-12 2016-06-29 北京蒙博润生物科技有限公司 片状交联透明质酸钠水凝胶的制备
WO2017082121A1 (ja) 2015-11-12 2017-05-18 テルモ株式会社 徐放性局所投与剤
CN105504316B (zh) * 2016-01-29 2017-12-29 清华大学 一种透明质酸‑甲基纤维素复合凝胶的活性酯交联方法
CN107998437B (zh) * 2016-10-31 2021-07-13 常州药物研究所有限公司 纳米交联透明质酸钠凝胶及其制备方法和应用
IL269506B2 (en) 2017-03-22 2024-04-01 Genentech Inc Hydrogel cross-linked hyaluronic acid prodrug compositions and methods
CN108047351A (zh) * 2017-12-15 2018-05-18 浙江景嘉医疗科技有限公司 一种低交联度透明质酸钠的制备方法
IL306070A (en) 2018-05-03 2023-11-01 Collplant Ltd Dermal fillers and their uses
CN109531857B (zh) * 2019-01-02 2020-11-06 华熙生物科技股份有限公司 一种透明质酸或其盐颗粒的制备方法及所得产品
CN110038161B (zh) * 2019-04-29 2021-07-30 上海交通大学 一种新型透明质酸流动凝胶及其制备方法和应用
CN113061265A (zh) * 2021-02-18 2021-07-02 中国人民解放军空军军医大学 一种多糖类水凝胶,其制备方法及其应用
CN113413484B (zh) * 2021-06-21 2023-02-10 浙江苏嘉医疗器械股份有限公司 可用于人体软组织填充的植入材料
KR102640893B1 (ko) * 2021-11-12 2024-02-27 주식회사 유영제약 히알루론산 가교물을 포함하는 조성물의 제조방법
CN115246889B (zh) * 2022-09-23 2023-01-10 常熟威怡科技有限公司 一种羧甲基纤维素锂及其制备方法和应用
CN117064067A (zh) * 2023-08-07 2023-11-17 湖北工业大学 一种具有可控酵解速率的膳食纤维及其制备方法与应用
CN120025572B (zh) * 2025-04-21 2025-07-25 上海惠盾因泰生物科技有限公司 一种具有抗酶解性能的葡聚糖-透明质酸钠凝胶的制备方法

Family Cites Families (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IN163192B (de) 1983-10-11 1988-08-20 Fidia Spa
CA1238043A (en) * 1983-12-15 1988-06-14 Endre A. Balazs Water insoluble preparations of hyaluronic acid and processes therefor
JPS60166301A (ja) * 1984-02-10 1985-08-29 Okura Ind Co Ltd セルロ−ス系材料成形品の製造方法
US4582865A (en) * 1984-12-06 1986-04-15 Biomatrix, Inc. Cross-linked gels of hyaluronic acid and products containing such gels
SE8501022L (sv) * 1985-03-01 1986-09-02 Pharmacia Ab Format alster och forfarande for dess framstellning
SE452469B (sv) * 1986-06-18 1987-11-30 Pharmacia Ab Material bestaende av en tverbunden karboxylgrupphaltig polysackarid och forfarande vid framstellning av detsamma
DE3726454A1 (de) * 1987-08-08 1989-02-16 Behringwerke Ag Thiolgruppenhaltige polymere, verfahren zu ihrer herstellung und ihre verwendung
IT1219587B (it) * 1988-05-13 1990-05-18 Fidia Farmaceutici Polisaccaridi carbossiilici autoreticolati
GB9024223D0 (en) * 1990-11-07 1990-12-19 Fermentech Ltd Production of hyaluronic acid
JPH05140201A (ja) * 1991-11-25 1993-06-08 Shiseido Co Ltd 架橋ヒアルロン酸ゲル及びその製造方法
JPH06102229A (ja) * 1992-09-18 1994-04-15 Daikin Ind Ltd 半透性膜およびその製造方法
US5579769A (en) * 1992-12-02 1996-12-03 Shiseido Company, Ltd. Coupling medium for probe of ultrasonograph
FR2717815A1 (fr) * 1994-03-25 1995-09-29 Gel Sciences Inc Nouveaux polymères gélifiables à base d'acide hyaluronique et leur procédé de préparation.
US5690961A (en) * 1994-12-22 1997-11-25 Hercules Incorporated Acidic polysaccharides crosslinked with polycarboxylic acids and their uses
US5827937A (en) * 1995-07-17 1998-10-27 Q Med Ab Polysaccharide gel composition
GB9902412D0 (en) * 1999-02-03 1999-03-24 Fermentech Med Ltd Process
NO314525B1 (no) * 1999-04-22 2003-03-31 Thin Film Electronics Asa Fremgangsmåte ved fremstillingen av organiske halvledende innretninger i tynnfilm
FR2811996B1 (fr) * 2000-07-19 2003-08-08 Corneal Ind Reticulation de polysaccharide(s), preparation d'hydrogel(s) ; polysaccharide(s) et hydrogel(s) obtenus,leurs utilisations
CA2351253A1 (en) * 2000-11-10 2002-05-10 Groupe Lysac Inc./Lysac Group Inc. Crosslinked polysaccharide, obtained by crosslinking with substituted polyethylene glycol, as superabsorbent
TW574301B (en) * 2001-05-02 2004-02-01 Ind Tech Res Inst Manufacturing method of epoxide crosslinked polysaccharides matrix
AU2003901834A0 (en) * 2003-04-17 2003-05-01 Clearcoll Pty Ltd Cross-linked polysaccharide compositions

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AU2003901834A0 (en) 2003-05-01
ES2349924T3 (es) 2011-01-13
WO2004092223A1 (en) 2004-10-28
EP1613663A4 (de) 2006-10-11
EP1613663B1 (de) 2010-08-04
JP2008133474A (ja) 2008-06-12
CA2522232A1 (en) 2004-10-28
DE602004028455D1 (de) 2010-09-16
KR20060008906A (ko) 2006-01-27
CN100509858C (zh) 2009-07-08
EP1613663A1 (de) 2006-01-11
CN1774450A (zh) 2006-05-17
JP2006523731A (ja) 2006-10-19
US8877243B2 (en) 2014-11-04
CA2522232C (en) 2007-07-03
US20140105852A1 (en) 2014-04-17
MXPA05011098A (es) 2005-12-15
BRPI0409890A (pt) 2006-05-23

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