ATE479424T1 - Prostaglandine enthaltende ophthalmische emulsionen - Google Patents

Prostaglandine enthaltende ophthalmische emulsionen

Info

Publication number: ATE479424T1
Authority: AT; Austria
Prior art keywords: sub; emulsions containing; prostaglandins; emulsions; oily core
Prior art date: 2005-10-10

Application number

AT06806156T

Other languages

English (en)

Inventor

Betty Philips

Severine Bague

Laura Rabinovich-Guilatt

Gregory Lambert

Original Assignee

Novagali Pharma Sa

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2005-10-10

Filing date

2006-10-10

Publication date

2010-09-15

2005-10-10 Priority claimed from PCT/EP2005/011648 external-priority patent/WO2006050836A2/en

2006-10-10 Application filed by Novagali Pharma Sa filed Critical Novagali Pharma Sa

2010-09-15 Application granted granted Critical

2010-09-15 Publication of ATE479424T1 publication Critical patent/ATE479424T1/de

Links

239000000839 emulsion Substances 0.000 title abstract 4
150000003180 prostaglandins Chemical class 0.000 title abstract 3
229940094443 oxytocics prostaglandins Drugs 0.000 title abstract 2
125000002091 cationic group Chemical group 0.000 abstract 2
208000010412 Glaucoma Diseases 0.000 abstract 1
206010030043 Ocular hypertension Diseases 0.000 abstract 1
229960002470 bimatoprost Drugs 0.000 abstract 1
AQOKCDNYWBIDND-FTOWTWDKSA-N bimatoprost Chemical compound CCNC(=O)CCC\C=C/C[C@H]1[C@@H](O)C[C@@H](O)[C@@H]1\C=C\[C@@H](O)CCC1=CC=CC=C1 AQOKCDNYWBIDND-FTOWTWDKSA-N 0.000 abstract 1
239000003795 chemical substances by application Substances 0.000 abstract 1
239000000084 colloidal system Substances 0.000 abstract 1
XXUPXHKCPIKWLR-JHUOEJJVSA-N isopropyl unoprostone Chemical group CCCCCCCC(=O)CC[C@H]1[C@H](O)C[C@H](O)[C@@H]1C\C=C/CCCC(=O)OC(C)C XXUPXHKCPIKWLR-JHUOEJJVSA-N 0.000 abstract 1
229960001160 latanoprost Drugs 0.000 abstract 1
GGXICVAJURFBLW-CEYXHVGTSA-N latanoprost Chemical compound CC(C)OC(=O)CCC\C=C/C[C@H]1[C@@H](O)C[C@@H](O)[C@@H]1CC[C@@H](O)CCC1=CC=CC=C1 GGXICVAJURFBLW-CEYXHVGTSA-N 0.000 abstract 1
239000000203 mixture Substances 0.000 abstract 1
239000002736 nonionic surfactant Substances 0.000 abstract 1
239000002245 particle Substances 0.000 abstract 1
239000000126 substance Substances 0.000 abstract 1
229960004458 tafluprost Drugs 0.000 abstract 1
WSNODXPBBALQOF-VEJSHDCNSA-N tafluprost Chemical compound CC(C)OC(=O)CCC\C=C/C[C@H]1[C@@H](O)C[C@@H](O)[C@@H]1\C=C\C(F)(F)COC1=CC=CC=C1 WSNODXPBBALQOF-VEJSHDCNSA-N 0.000 abstract 1
229960002368 travoprost Drugs 0.000 abstract 1
MKPLKVHSHYCHOC-AHTXBMBWSA-N travoprost Chemical compound CC(C)OC(=O)CCC\C=C/C[C@H]1[C@@H](O)C[C@@H](O)[C@@H]1\C=C\[C@@H](O)COC1=CC=CC(C(F)(F)F)=C1 MKPLKVHSHYCHOC-AHTXBMBWSA-N 0.000 abstract 1
229950008081 unoprostone isopropyl Drugs 0.000 abstract 1
XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
- A61K9/1075—Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/557—Eicosanoids, e.g. leukotrienes or prostaglandins
- A61K31/5575—Eicosanoids, e.g. leukotrienes or prostaglandins having a cyclopentane, e.g. prostaglandin E2, prostaglandin F2-alpha
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0048—Eye, e.g. artificial tears
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/06—Antiglaucoma agents or miotics
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Veterinary Medicine (AREA)
Pharmacology & Pharmacy (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Animal Behavior & Ethology (AREA)
Epidemiology (AREA)
Ophthalmology & Optometry (AREA)
Bioinformatics & Cheminformatics (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Engineering & Computer Science (AREA)
Organic Chemistry (AREA)
Dispersion Chemistry (AREA)
Biophysics (AREA)
Molecular Biology (AREA)
Medicinal Preparation (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

AT06806156T 2005-10-10 2006-10-10 Prostaglandine enthaltende ophthalmische emulsionen ATE479424T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
PCT/EP2005/011648 WO2006050836A2 (en)	2004-11-09	2005-10-10	Ophthalmic emulsions containing prostaglandins
PCT/EP2006/009783 WO2007042262A2 (en)	2005-10-10	2006-10-10	Ophthalmic emulsions containing prostaglandins

Publications (1)

Publication Number	Publication Date
ATE479424T1 true ATE479424T1 (de)	2010-09-15

Family

ID=37600871

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT06806156T ATE479424T1 (de)	2005-10-10	2006-10-10	Prostaglandine enthaltende ophthalmische emulsionen

Country Status (13)

Country	Link
EP (1)	EP1937212B1 (de)
JP (1)	JP5247453B2 (de)
KR (1)	KR101286807B1 (de)
CN (1)	CN101282714B (de)
AT (1)	ATE479424T1 (de)
AU (1)	AU2006301493B2 (de)
CA (1)	CA2625568C (de)
DE (1)	DE602006016628D1 (de)
DK (1)	DK1937212T3 (de)
ES (1)	ES2351358T3 (de)
PL (1)	PL1937212T3 (de)
PT (1)	PT1937212E (de)
WO (1)	WO2007042262A2 (de)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EP1985298A1 (de)	2007-04-24	2008-10-29	Azad Pharma AG	Prostaglandinhaltige Öl-in-Wasser-Emulsionen für das Auge
CA2730221C (en) *	2007-07-09	2016-02-02	Novagali Pharma Sa	Oil in water emulsion comprising nsaids and quaternary ammonium halides
US8512687B2 (en)	2007-07-09	2013-08-20	Novagali Pharma Sa	Oil in water emulsion comprising NSAIDs and quaternary ammonium halides
ES2352296T3 (es) *	2007-07-09	2011-02-17	Novagali Pharma S.A.	Emulsión de aceite en agua que comprende aine y haluros de amonio cuaternarios.
EP2044951A1 (de) *	2007-10-02	2009-04-08	Merz Pharma GmbH & Co. KGaA	Die Verwendung von Substanzen zur Behandlung des Verlustes des Augenlichts bei Menschen mit Glaukom und anderer degenerativer Augenerkrankungen
EP2229174A1 (de) *	2007-12-04	2010-09-22	Novagali Pharma S.A.	Zusammensetzungen mit einem kortikosteroid-prodrug wie dexamethasonpalmitat zur behandlung von augenerkrankungen
EP2127638A1 (de)	2008-05-30	2009-12-02	Santen Pharmaceutical Co., Ltd	Verfahren und Zusammensetzung zur Behandlung von Augenhochdruck und Glaukom
EP2228058A1 (de) *	2009-03-04	2010-09-15	Novagali Pharma S.A.	Anionische Öl-in-Wasser-Emulsion mit Prostaglandinen und Verwendungen dafür
EP2228057A1 (de) *	2009-03-04	2010-09-15	Novagali Pharma S.A.	Kationische Öl-in-Wasser-Emulsionen mit Prostaglandinen und Verwendungen dafür
US8501800B2 (en) *	2009-03-05	2013-08-06	Insite Vision Incorporated	Controlled-release ophthalmic vehicles
CA2773597A1 (en) *	2009-09-17	2011-03-24	Senju Pharmaceutical Co., Ltd.	Latanoprost-containing aqueous eye drops and method for inhibiting adsorption of latanoprost to resin
EP2389939A1 (de) *	2010-05-28	2011-11-30	Novagali Pharma S.A.	Verwendung von Prostaglandinen F2alpha und Analoga zur Heilung von Horn- und Bindehautläsionen
US9061034B2 (en)	2010-07-29	2015-06-23	Allergan, Inc.	Preservative free bimatoprost and timolol solutions
HUE059325T2 (hu) *	2010-07-29	2022-11-28	Allergan Inc	Tartósítószer-mentes bimatoprost és timolol oldatok
US20130065888A1 (en) *	2011-08-15	2013-03-14	Biserka Cetina-Cizmek	Ophthalmic formulations and processes for their preparation
EP2567689A1 (de)	2011-09-12	2013-03-13	Visiotact Pharma	Ophthalmische Zusammensetzungen enhaltend Prostaglandin-F2-alpha-Derivate und Hyaluronsäure
WO2013052380A2 (en) *	2011-10-05	2013-04-11	Allergan, Inc.	Compositions for enhancing nail health
KR102433489B1 (ko) *	2013-03-14	2022-08-17	팬옵티카, 인크.	눈의 후안부로의 약물 전달을 위한 안구용 제제
KR20150000405A (ko) *	2013-06-24	2015-01-02	한국콜마주식회사	난용성 의약품의 수중유적형 에멀젼 조성물 및 이의 제조방법
WO2014207769A1 (en)	2013-06-27	2014-12-31	Mylan Laboratories Ltd	Process for the preparation of nepafenac
WO2016013993A1 (en)	2014-07-25	2016-01-28	Imuneks Farma Llac Sanayi Ve Ticaret A.Ş.	Stable preservative free ophthalmic formulations of opioid antagonists
JP6404785B2 (ja) *	2015-08-12	2018-10-17	日本電信電話株式会社	生体分子移動度制御方法および電気泳動槽
CN109498597B (zh) *	2018-12-07	2021-12-14	佛山市正典生物技术有限公司	一种喹烯酮微丸及其制备方法
JP6855026B1 (ja) *	2020-11-09	2021-04-07	東亜薬品株式会社	タフルプロスト点眼液
CN116725954B (zh) *	2023-07-12	2026-03-31	浙江大学	一种具有抗氧化功能的纳米制剂及治疗青光眼用途
EP4791355A1 (de)	2023-10-11	2026-08-19	Santen SAS	Kit zur stabilisierung von prostaglandinemulsionen
JP7799358B1 (ja) *	2025-06-27	2026-01-15	株式会社シンコーホールディングス	Ｐｆａｓの処理方法およびフッ化カルシウムの製造方法

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JPH0818989B2 (ja) *	1984-01-12	1996-02-28	株式会社ミドリ十字	脂肪乳剤中のプロスタグランジンの安定化方法
JP2602964B2 (ja) *	1989-10-16	1997-04-23	裕水島	プロスタグランジン類縁体およびその脂肪乳剤
IL101241A (en) *	1992-03-16	1997-11-20	Yissum Res Dev Co	Pharmaceutical or cosmetic composition comprising stabilized oil-in-water type emulsion as carrier
US6011062A (en) *	1994-12-22	2000-01-04	Alcon Laboratories, Inc.	Storage-stable prostaglandin compositions
EP1441696B1 (de) *	2001-11-01	2010-05-19	Yissum Research Development Company Of The Hebrew University Of Jerusalem	Verfahren und zusammensetzung zur behandlung von trockenen augen
KR100446960B1 (ko) *	2001-12-04	2004-09-01	김종국	프로스타글란딘 ｅ1을 포함하는 온도감응성 에멀젼 외용제조성물
US7074827B2 (en) *	2002-10-24	2006-07-11	Sucampo Ag (Usa) Inc.	Method for treating ocular hypertension and glaucoma
DE602004023106D1 (de)	2003-11-07	2009-10-22	Senju Pharma Co	Pharmazeutische zusammensetzung mit prostaglandin

2006
- 2006-10-10 CN CN2006800375133A patent/CN101282714B/zh not_active Expired - Fee Related
- 2006-10-10 DE DE602006016628T patent/DE602006016628D1/de active Active
- 2006-10-10 AU AU2006301493A patent/AU2006301493B2/en active Active
- 2006-10-10 DK DK06806156.3T patent/DK1937212T3/da active
- 2006-10-10 JP JP2008533955A patent/JP5247453B2/ja not_active Expired - Fee Related
- 2006-10-10 ES ES06806156T patent/ES2351358T3/es active Active
- 2006-10-10 EP EP06806156A patent/EP1937212B1/de active Active
- 2006-10-10 PL PL06806156T patent/PL1937212T3/pl unknown
- 2006-10-10 AT AT06806156T patent/ATE479424T1/de not_active IP Right Cessation
- 2006-10-10 PT PT06806156T patent/PT1937212E/pt unknown
- 2006-10-10 CA CA2625568A patent/CA2625568C/en active Active
- 2006-10-10 WO PCT/EP2006/009783 patent/WO2007042262A2/en not_active Ceased
- 2006-10-10 KR KR1020087008587A patent/KR101286807B1/ko active Active

Also Published As

Publication number	Publication date
WO2007042262A8 (en)	2008-05-08
CA2625568A1 (en)	2007-04-19
JP5247453B2 (ja)	2013-07-24
WO2007042262A3 (en)	2007-08-16
CN101282714B (zh)	2012-12-12
DK1937212T3 (da)	2010-12-13
CA2625568C (en)	2013-10-08
KR20080066675A (ko)	2008-07-16
ES2351358T3 (es)	2011-02-03
AU2006301493A1 (en)	2007-04-19
DE602006016628D1 (de)	2010-10-14
AU2006301493B2 (en)	2013-01-10
JP2009511442A (ja)	2009-03-19
PL1937212T3 (pl)	2011-02-28
WO2007042262A2 (en)	2007-04-19
EP1937212A2 (de)	2008-07-02
CN101282714A (zh)	2008-10-08
EP1937212B1 (de)	2010-09-01
PT1937212E (pt)	2010-11-30
KR101286807B1 (ko)	2013-07-23

Legal Events

Date	Code	Title	Description
2011-03-15	RER	Ceased as to paragraph 5 lit. 3 law introducing patent treaties

Publication	Publication Date	Title
DE602006016628D1 (de)	2010-10-14	Prostaglandine enthaltende ophthalmische emulsionen
WO2006050836A3 (en)	2007-07-12	Ophthalmic emulsions containing prostaglandins
BR9808016A (pt)	2000-03-08	Composições e métodos para redução da hipertensão ocular
AU2006227757B2 (en)	2011-07-14	Enhanced bimatoprost ophthalmic solution
KR101702157B1 (ko)	2017-02-13	안과용 조성물
DK0639563T4 (en)	2016-01-11	Use of fluprostenol isopropyl ester for the manufacture of a medicament for the treatment of glaucoma and ocular hypertension
MX2007005545A (es)	2007-07-05	Emulsion oftalmica tipo aceite en agua con potencial zeta positivo estable.
RU2009143324A (ru)	2011-05-27	Офтальмические эмульсии масло-в-воде, содержащие простагландины
ES2542728T3 (es)	2015-08-10	Composiciones farmacéuticas que tienen la biodisponibilidad deseable
ES2161895T3 (es)	2001-12-16	Emulsiones especificas de la glandula lagrimal para aplicacion topica a tejidos oculares.
HRP20170769T1 (hr)	2017-08-11	Postupak i pripravak za liječenje očne hipertenzije i glaukoma
JP2010524992A5 (de)	2011-04-07
EP2197449A2 (de)	2010-06-23	Neuartige ophthalmische zusammensetzungen
FR2890559B1 (fr)	2011-06-24	Mousses dermatologiques a base de metronidazole et emulsions pour la preparation
CO5570649A2 (es)	2005-10-31	Producto antitranspirante en gel liquido de alta eficiencia
ATE469958T1 (de)	2010-06-15	Wässrige hochsaure reinigungsmittel für feste oberflächen
JP2014515383A5 (de)	2014-08-07
JP2008528490A (ja)	2008-07-31	安定なプロスタグランジン含有組成物
DK1532981T3 (da)	2008-01-28	Stabile öjendråber, der indeholder latanoprost som den aktive bestanddel
RU2009120545A (ru)	2010-12-10	Модуляторы связывания pai-1 для лечения глазных болезней
MX2011009258A (es)	2011-09-27	Emulsiones aceite-en-agua cationicas conteniendo prostaglandinas y usos de las mismas.
DE602006000518D1 (de)	2008-03-27	Schäumende O/W-Emulsion und ihre Verwendung in der Kosmetik
RU2008105323A (ru)	2009-08-20	Консервирующая композиция для офтальмологического применения
DK3107906T3 (en)	2019-03-18	REDUCED CENTRAL CORNER MAP THICKNESS USING HYDROFILE ESTER PRODRUGS OF BETA-CHLORCYCLOPENTANE
FR2883474B1 (fr)	2009-04-24	Emulsion h/e moussante et son utilisation dans le domaine cosmetique