ATE480238T1 - Analoge des 5(e)bromovinyluracils und verwandte pyrimidinnucleoside als antivirale mittel und verwendungsmethoden - Google Patents

Analoge des 5(e)bromovinyluracils und verwandte pyrimidinnucleoside als antivirale mittel und verwendungsmethoden

Info

Publication number
ATE480238T1
ATE480238T1 AT00948851T AT00948851T ATE480238T1 AT E480238 T1 ATE480238 T1 AT E480238T1 AT 00948851 T AT00948851 T AT 00948851T AT 00948851 T AT00948851 T AT 00948851T AT E480238 T1 ATE480238 T1 AT E480238T1
Authority
AT
Austria
Prior art keywords
bromovinyluracil
analogue
methods
antiviral agents
pyrimidine nucleosides
Prior art date
Application number
AT00948851T
Other languages
English (en)
Inventor
Yung-Chi Cheng
Chung Chu
Ling Li
Yongseok Choi
Original Assignee
Univ Yale
Univ Georgia
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Yale, Univ Georgia filed Critical Univ Yale
Application granted granted Critical
Publication of ATE480238T1 publication Critical patent/ATE480238T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/06—Pyrimidine radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
AT00948851T 1999-07-21 2000-07-20 Analoge des 5(e)bromovinyluracils und verwandte pyrimidinnucleoside als antivirale mittel und verwendungsmethoden ATE480238T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US09/358,028 US6653318B1 (en) 1999-07-21 1999-07-21 5-(E)-Bromovinyl uracil analogues and related pyrimidine nucleosides as anti-viral agents and methods of use
PCT/US2000/019881 WO2001006986A2 (en) 1999-07-21 2000-07-20 5-(e)-bromovinyl uracil analogues and related pyrimidine nucleosides as anti-viral agents and methods of use

Publications (1)

Publication Number Publication Date
ATE480238T1 true ATE480238T1 (de) 2010-09-15

Family

ID=23408010

Family Applications (1)

Application Number Title Priority Date Filing Date
AT00948851T ATE480238T1 (de) 1999-07-21 2000-07-20 Analoge des 5(e)bromovinyluracils und verwandte pyrimidinnucleoside als antivirale mittel und verwendungsmethoden

Country Status (8)

Country Link
US (2) US6653318B1 (de)
EP (1) EP1204415B1 (de)
CN (1) CN1420773A (de)
AT (1) ATE480238T1 (de)
AU (1) AU767676B2 (de)
CA (1) CA2378370C (de)
DE (1) DE60044937D1 (de)
WO (1) WO2001006986A2 (de)

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2385349A1 (en) 1999-09-24 2001-04-05 Francis J. Giles Method for the treatment or prevention of viral infection using nucleoside analogues
US6566365B1 (en) 1999-11-04 2003-05-20 Biochem Pharma Inc. Method for the treatment of Flaviviridea viral infection using nucleoside analogues
CA2470938A1 (en) 2001-12-20 2003-07-03 Beth Israel Deaconess Medical Center Treatment of ebv and khsv infection and associated abnormal cellular proliferation
CN101066987B (zh) * 2007-06-14 2010-05-19 上海交通大学 溴呋啶的制备方法
WO2012051492A2 (en) * 2010-10-14 2012-04-19 University Of Georgia Research Foundation, Inc. Compounds and methods for inhibiting hiv latency
CN102649788B (zh) * 2011-02-28 2015-03-25 四川大学 β-L-2’-脱氧-胸腺嘧啶核苷衍生物及其制备方法和用途
EP4423100A4 (de) 2021-10-29 2025-04-23 University of Georgia Research Foundation, Inc. Prodrugs von l-bhdu und verfahren zur behandlung von virusinfektionen

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Also Published As

Publication number Publication date
WO2001006986A3 (en) 2001-10-25
US6653318B1 (en) 2003-11-25
WO2001006986A2 (en) 2001-02-01
DE60044937D1 (de) 2010-10-21
EP1204415A4 (de) 2002-09-04
EP1204415A2 (de) 2002-05-15
AU767676B2 (en) 2003-11-20
CA2378370C (en) 2010-01-26
CN1420773A (zh) 2003-05-28
AU6228800A (en) 2001-02-13
EP1204415B1 (de) 2010-09-08
US20040053891A1 (en) 2004-03-18
CA2378370A1 (en) 2001-02-01

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