ATE480531T1 - Verfahren zur herstellung von benzopyran-2- olderivaten - Google Patents
Verfahren zur herstellung von benzopyran-2- olderivatenInfo
- Publication number
- ATE480531T1 ATE480531T1 AT07734680T AT07734680T ATE480531T1 AT E480531 T1 ATE480531 T1 AT E480531T1 AT 07734680 T AT07734680 T AT 07734680T AT 07734680 T AT07734680 T AT 07734680T AT E480531 T1 ATE480531 T1 AT E480531T1
- Authority
- AT
- Austria
- Prior art keywords
- olderivates
- benzopyran
- producing
- producing benzopyran
- Prior art date
Links
- 238000004519 manufacturing process Methods 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
- C07D311/06—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 2
- C07D311/20—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 2 hydrogenated in the hetero ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C213/00—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton
- C07C213/02—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton by reactions involving the formation of amino groups from compounds containing hydroxy groups or etherified or esterified hydroxy groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C219/00—Compounds containing amino and esterified hydroxy groups bound to the same carbon skeleton
- C07C219/26—Compounds containing amino and esterified hydroxy groups bound to the same carbon skeleton having esterified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
- C07C219/28—Compounds containing amino and esterified hydroxy groups bound to the same carbon skeleton having esterified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton having amino groups bound to acyclic carbon atoms of the carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
- C07C45/67—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
- C07C45/68—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms
- C07C45/69—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms by addition to carbon-to-carbon double or triple bonds
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
- C07D311/58—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Pyrane Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US80306806P | 2006-05-24 | 2006-05-24 | |
| PCT/IB2007/001379 WO2007138440A1 (en) | 2006-05-24 | 2007-05-21 | Process for the production of benzopyran-2-ol derivatives |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE480531T1 true ATE480531T1 (de) | 2010-09-15 |
Family
ID=37232871
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT07734680T ATE480531T1 (de) | 2006-05-24 | 2007-05-21 | Verfahren zur herstellung von benzopyran-2- olderivaten |
Country Status (24)
| Country | Link |
|---|---|
| US (1) | US8067594B2 (de) |
| EP (1) | EP2029567B1 (de) |
| JP (1) | JP5269349B2 (de) |
| KR (1) | KR101087326B1 (de) |
| CN (1) | CN101454304B (de) |
| AR (1) | AR061112A1 (de) |
| AT (1) | ATE480531T1 (de) |
| AU (1) | AU2007266761B2 (de) |
| BR (1) | BRPI0712037A2 (de) |
| CA (1) | CA2651978C (de) |
| CY (1) | CY1110823T1 (de) |
| DE (1) | DE602007009096D1 (de) |
| DK (1) | DK2029567T3 (de) |
| ES (1) | ES2350056T3 (de) |
| IL (2) | IL194959A0 (de) |
| MX (1) | MX2008012976A (de) |
| NZ (1) | NZ571988A (de) |
| PL (1) | PL2029567T3 (de) |
| PT (1) | PT2029567E (de) |
| RU (1) | RU2397163C2 (de) |
| SG (1) | SG158070A1 (de) |
| TW (1) | TWI343381B (de) |
| WO (1) | WO2007138440A1 (de) |
| ZA (1) | ZA200808527B (de) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2007144097A1 (en) | 2006-06-12 | 2007-12-21 | Schwarz Pharma Ag | New chiral intermediate, process for producing the same and its use in the manufacture of tolterodine, fesoterodine, or the active metabolite thereof |
| BRPI1010820A2 (pt) * | 2009-05-11 | 2019-09-24 | Ratiopharm Gmbh | desfesoterodina na forma de um sal de acido tartarico |
| SI2281801T1 (sl) | 2009-07-27 | 2014-04-30 | Crystal Pharma, S.A.U. | Postopek za pridobivanje 3,3-diphenilpropilamina |
| IT1396373B1 (it) * | 2009-10-29 | 2012-11-19 | Dipharma Francis Srl | Procedimento per la preparazione di fesoterodina. |
| EP2364966A1 (de) | 2010-03-09 | 2011-09-14 | LEK Pharmaceuticals d.d. | Verfahren zur Herstellung von 3-(2-hydroxy-5-substituierten phenyl)-3-phenylpropylaminen, Zwischenprodukte zur Herstellung von Hydroxytolterodin |
| IT1401451B1 (it) * | 2010-06-10 | 2013-07-26 | Chemi Spa | Nuovo processo di preparazione di 2-idrossi-4-fenil-3,4-diidro-2h-cromen-6-il-metanolo e (r)-2-[3-(diisopropilammino)-1-fenilpropil]-4-(idrossimetil)fenolo. |
| WO2011158257A1 (en) | 2010-06-18 | 2011-12-22 | Panacea Biotec Ltd | Preparation process of fesoterodine and intermediates |
| CN102329244A (zh) * | 2010-07-13 | 2012-01-25 | 凯瑞斯德生化(苏州)有限公司 | 一种rs-托特罗定的制备方法及中间体化合物 |
| WO2012025941A2 (en) | 2010-08-25 | 2012-03-01 | Cadila Healthcare Limited | Processes for the preparation of fesoterodine |
| IT1403094B1 (it) | 2010-12-09 | 2013-10-04 | Dipharma Francis Srl | Procedimento per la preparazione di fesoterodina o un suo sale |
| JP6234999B2 (ja) | 2012-05-04 | 2017-11-22 | クリスタル ファルマ、エセ、ア、ウＣｒｙｓｔａｌ Ｐｈａｒｍａ，Ｓ．Ａ．Ｕ． | 光学的に活性な３，３−ジフェニルプロピルアミンを調製するための方法 |
| PL2760822T3 (pl) | 2012-06-14 | 2016-09-30 | Sole desfezoterodyny | |
| ITMI20121232A1 (it) | 2012-07-16 | 2014-01-17 | Cambrex Profarmaco Milano Srl | Procedimento per la preparazione di 2-(3-n,n-diisopropilamino-1-fenilpropil)-4-idrossimetil-fenolo e suoi derivati |
| CN103044273B (zh) * | 2012-11-29 | 2014-12-24 | 珠海保税区丽珠合成制药有限公司 | 一种酒石酸托特罗定的合成方法 |
| WO2017137955A1 (en) | 2016-02-14 | 2017-08-17 | Celestis Pharmaceuticals Pvt. Ltd. | Novel (r) and rac 3-(2-(allyloxy)-5-methylphenyl)-n,n-diisopropyl-3- phenylpropan-1-amine and its use for synthesis of (r) and rac-2-(3- (diisopropylamino)-1-phenylpropyl)-4-(hydroxymethyl)phenol |
| RU2652119C1 (ru) * | 2016-12-14 | 2018-04-25 | федеральное государственное бюджетное образовательное учреждение высшего образования "Самарский государственный технический университет" | Способ получения производных хроман-2-аминов |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE19525137C2 (de) * | 1995-07-11 | 2003-02-27 | Gruenenthal Gmbh | 6-Dimethylaminomethyl-1-phenyl-cyclohexanverbin -dungen als Zwischenprodukte zur Herstellung pharmazeutischer Wirkstoffe |
| KR20000057548A (ko) * | 1996-12-13 | 2000-09-25 | 알프레드 엘. 미첼슨 | 광학적 전송물질 및 결합재 |
| EP0957073A1 (de) * | 1998-05-12 | 1999-11-17 | Schwarz Pharma Ag | 3,3-Diphenylpropylaminderivate |
| DE29923134U1 (de) * | 1999-11-16 | 2000-06-29 | Schwarz Pharma Ag, 40789 Monheim | Stabile Salze neuartiger Derviate von 3,3-Diphenylpropylaminen |
| SE9904850D0 (sv) | 1999-12-30 | 1999-12-30 | Pharmacia & Upjohn Ab | Novel process and intermediates |
| DE10033016A1 (de) * | 2000-07-07 | 2002-01-24 | Sanol Arznei Schwarz Gmbh | Verfahren zur Herstellung von 3,3-Diarylpropylaminen |
| US7173139B2 (en) | 2001-06-29 | 2007-02-06 | California Institute Of Technology | Enantioselective 1,4-addition of aromatic nucleophiles to α,β-unsaturated aldehydes using chiral organic catalysts |
| MXPA05011225A (es) * | 2003-04-18 | 2005-12-14 | Pharmacia & Upjohn Co Llc | Politerapias. |
-
2007
- 2007-05-21 KR KR1020087028577A patent/KR101087326B1/ko not_active Expired - Fee Related
- 2007-05-21 CN CN2007800191401A patent/CN101454304B/zh active Active
- 2007-05-21 DE DE602007009096T patent/DE602007009096D1/de active Active
- 2007-05-21 WO PCT/IB2007/001379 patent/WO2007138440A1/en not_active Ceased
- 2007-05-21 PL PL07734680T patent/PL2029567T3/pl unknown
- 2007-05-21 RU RU2008141413/04A patent/RU2397163C2/ru active
- 2007-05-21 DK DK07734680.7T patent/DK2029567T3/da active
- 2007-05-21 ES ES07734680T patent/ES2350056T3/es active Active
- 2007-05-21 NZ NZ571988A patent/NZ571988A/en not_active IP Right Cessation
- 2007-05-21 SG SG200907701-7A patent/SG158070A1/en unknown
- 2007-05-21 PT PT07734680T patent/PT2029567E/pt unknown
- 2007-05-21 AT AT07734680T patent/ATE480531T1/de active
- 2007-05-21 EP EP07734680A patent/EP2029567B1/de active Active
- 2007-05-21 BR BRPI0712037-0A patent/BRPI0712037A2/pt not_active Application Discontinuation
- 2007-05-21 US US12/302,228 patent/US8067594B2/en active Active
- 2007-05-21 MX MX2008012976A patent/MX2008012976A/es active IP Right Grant
- 2007-05-21 AU AU2007266761A patent/AU2007266761B2/en not_active Ceased
- 2007-05-21 CA CA2651978A patent/CA2651978C/en not_active Expired - Fee Related
- 2007-05-22 JP JP2007135615A patent/JP5269349B2/ja active Active
- 2007-05-23 AR ARP070102234A patent/AR061112A1/es not_active Application Discontinuation
- 2007-05-23 TW TW096118354A patent/TWI343381B/zh not_active IP Right Cessation
-
2008
- 2008-10-07 ZA ZA200808527A patent/ZA200808527B/xx unknown
- 2008-10-28 IL IL194959A patent/IL194959A0/en unknown
-
2010
- 2010-10-11 CY CY20101100903T patent/CY1110823T1/el unknown
-
2012
- 2012-06-14 IL IL220430A patent/IL220430A0/en unknown
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification |
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