ATE480554T1 - Rekombinanter leukotoxinimpfstoff aus fusobacterium necrophorum und dessen präparation - Google Patents
Rekombinanter leukotoxinimpfstoff aus fusobacterium necrophorum und dessen präparationInfo
- Publication number
- ATE480554T1 ATE480554T1 AT01932626T AT01932626T ATE480554T1 AT E480554 T1 ATE480554 T1 AT E480554T1 AT 01932626 T AT01932626 T AT 01932626T AT 01932626 T AT01932626 T AT 01932626T AT E480554 T1 ATE480554 T1 AT E480554T1
- Authority
- AT
- Austria
- Prior art keywords
- gene
- leukotoxin
- protein
- necrophorum
- sequenced
- Prior art date
Links
- FBUKMFOXMZRGRB-UHFFFAOYSA-N Coronaric acid Natural products CCCCCC=CCC1OC1CCCCCCCC(O)=O FBUKMFOXMZRGRB-UHFFFAOYSA-N 0.000 title abstract 4
- 101710170970 Leukotoxin Proteins 0.000 title abstract 4
- 241000605952 Fusobacterium necrophorum Species 0.000 title abstract 3
- 229960005486 vaccine Drugs 0.000 title 1
- 108090000623 proteins and genes Proteins 0.000 abstract 8
- 102000004169 proteins and genes Human genes 0.000 abstract 4
- 229920001184 polypeptide Polymers 0.000 abstract 3
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 3
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 3
- 101100075612 Aggregatibacter actinomycetemcomitans ltxA gene Proteins 0.000 abstract 1
- 108700026244 Open Reading Frames Proteins 0.000 abstract 1
- 150000001413 amino acids Chemical class 0.000 abstract 1
- 239000012228 culture supernatant Substances 0.000 abstract 1
- 230000036039 immunity Effects 0.000 abstract 1
- 230000003053 immunization Effects 0.000 abstract 1
- 238000002649 immunization Methods 0.000 abstract 1
- 230000005847 immunogenicity Effects 0.000 abstract 1
- 101150108880 lktA gene Proteins 0.000 abstract 1
- 239000002773 nucleotide Substances 0.000 abstract 1
- 125000003729 nucleotide group Chemical group 0.000 abstract 1
- 230000001681 protective effect Effects 0.000 abstract 1
- 238000011144 upstream manufacturing Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Genetics & Genomics (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US55825700A | 2000-04-25 | 2000-04-25 | |
| US09/841,786 US6669940B2 (en) | 2000-04-25 | 2001-04-24 | Recombinant fusobacterium necrophorum leukotoxin vaccine and preparation thereof |
| PCT/US2001/013240 WO2001080886A2 (en) | 2000-04-25 | 2001-04-25 | Recombinant fusobacterium necrophorum leukotoxin vaccine and preparation thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE480554T1 true ATE480554T1 (de) | 2010-09-15 |
Family
ID=24228816
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT01932626T ATE480554T1 (de) | 2000-04-25 | 2001-04-25 | Rekombinanter leukotoxinimpfstoff aus fusobacterium necrophorum und dessen präparation |
Country Status (4)
| Country | Link |
|---|---|
| US (2) | US6669940B2 (de) |
| AT (1) | ATE480554T1 (de) |
| DE (1) | DE60143029D1 (de) |
| ES (1) | ES2352322T3 (de) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6669940B2 (en) * | 2000-04-25 | 2003-12-30 | Kansas University Research Foundation | Recombinant fusobacterium necrophorum leukotoxin vaccine and preparation thereof |
| NZ553315A (en) | 2004-08-25 | 2009-12-24 | Epitopix Llc | Fusobacterium polypeptides and methods of use |
| EP2211727B1 (de) | 2007-11-14 | 2014-03-12 | Adhezion Biomedical, LLC | Cyanoacrylat-gewebekleber |
| US9308247B2 (en) | 2011-03-25 | 2016-04-12 | Kansas State University Research Foundation | Compositions and methods for detecting, treating, and protecting against fusobacterium infection |
| JP6301945B2 (ja) | 2012-11-29 | 2018-03-28 | コーネル ユニバーシティＣｏｒｎｅｌｌ Ｕｎｉｖｅｒｓｉｔｙ | 子宮内疾患のためのワクチン |
| EP3373964A1 (de) | 2015-11-09 | 2018-09-19 | Epitopix, LLC | Polypeptide des fusobacteriums und verfahren zur verwendung |
| CA3152764A1 (en) * | 2019-08-27 | 2021-03-04 | Relica Genomics Inc. | Transformed plants and methods for making and using the same |
| CN110613842B (zh) * | 2019-10-15 | 2022-03-15 | 黑龙江八一农垦大学 | 一种牛坏死杆菌的亚单位疫苗及其制备方法 |
| CN111154904A (zh) * | 2020-03-02 | 2020-05-15 | 黑龙江八一农垦大学 | 坏死杆菌白细胞毒素基因pcr诊断试剂盒及其建立方法 |
| CN114686445B (zh) * | 2022-03-29 | 2023-07-07 | 黑龙江八一农垦大学 | 一种用于检测坏死杆菌白细胞毒素的单克隆抗体、试剂盒及其应用 |
| CN117288947B (zh) * | 2023-10-07 | 2024-09-24 | 黑龙江八一农垦大学 | 一种牛坏死杆菌抗体间接elisa检测试剂盒及其应用 |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4152415A (en) | 1978-08-18 | 1979-05-01 | Iowa State University Research Foundation, Inc. | Method of increasing the effectiveness of oral vaccination for swine dysentery |
| US4203968A (en) | 1978-08-18 | 1980-05-20 | Iowa State University Research Foundation, Inc. | Combination vaccine for swine dysentery and method of use |
| US4919929A (en) | 1984-02-01 | 1990-04-24 | Stolle Research & Development Corporation | Mammal immunization |
| US5641653A (en) * | 1989-10-31 | 1997-06-24 | The Texas A&M University System | DNA encoding Actinobacillus pleuropneumoniae hemolysin |
| US5455034A (en) | 1992-06-26 | 1995-10-03 | Kansas State University Research Foundation | Fusobacterium necrophorum leukotoxoid vaccine |
| US6669940B2 (en) * | 2000-04-25 | 2003-12-30 | Kansas University Research Foundation | Recombinant fusobacterium necrophorum leukotoxin vaccine and preparation thereof |
| MXPA02010418A (es) * | 2000-04-25 | 2003-04-25 | Univ Kansas State | Vacuna de leucotoxina de fusobacterium necrophorum recombinante y preparacion de la misma. |
-
2001
- 2001-04-24 US US09/841,786 patent/US6669940B2/en not_active Expired - Lifetime
- 2001-04-25 DE DE60143029T patent/DE60143029D1/de not_active Expired - Lifetime
- 2001-04-25 ES ES01932626T patent/ES2352322T3/es not_active Expired - Lifetime
- 2001-04-25 AT AT01932626T patent/ATE480554T1/de not_active IP Right Cessation
-
2008
- 2008-07-11 US US12/171,985 patent/US20090117142A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| US6669940B2 (en) | 2003-12-30 |
| DE60143029D1 (de) | 2010-10-21 |
| ES2352322T3 (es) | 2011-02-17 |
| US20020054883A1 (en) | 2002-05-09 |
| US20090117142A1 (en) | 2009-05-07 |
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Legal Events
| Date | Code | Title | Description |
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| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |