ATE480566T1 - Immuntherapeutische zusammensetzung und verfahren zur behandlung von prostatakrebs - Google Patents
Immuntherapeutische zusammensetzung und verfahren zur behandlung von prostatakrebsInfo
- Publication number
- ATE480566T1 ATE480566T1 AT99925216T AT99925216T ATE480566T1 AT E480566 T1 ATE480566 T1 AT E480566T1 AT 99925216 T AT99925216 T AT 99925216T AT 99925216 T AT99925216 T AT 99925216T AT E480566 T1 ATE480566 T1 AT E480566T1
- Authority
- AT
- Austria
- Prior art keywords
- prostate cancer
- treating prostate
- immunotherapeutic composition
- immunotherapeutic
- composition
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
- C07K16/42—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against immunoglobulins
- C07K16/4208—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against immunoglobulins against an idiotypic determinant on Ig
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/08—Drugs for disorders of the urinary system of the prostate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
- C07K16/40—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against enzymes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Immunology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Urology & Nephrology (AREA)
- Endocrinology (AREA)
- Reproductive Health (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US8928198P | 1998-06-15 | 1998-06-15 | |
| PCT/IB1999/001115 WO1999065523A1 (en) | 1998-06-15 | 1999-06-15 | Immunotherapeutic composition and method for the treatment of prostate cancer |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE480566T1 true ATE480566T1 (de) | 2010-09-15 |
Family
ID=22216751
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT99925216T ATE480566T1 (de) | 1998-06-15 | 1999-06-15 | Immuntherapeutische zusammensetzung und verfahren zur behandlung von prostatakrebs |
Country Status (9)
| Country | Link |
|---|---|
| US (3) | US6881405B2 (de) |
| EP (1) | EP1085905B1 (de) |
| JP (1) | JP2002518347A (de) |
| AT (1) | ATE480566T1 (de) |
| AU (1) | AU768002B2 (de) |
| CA (1) | CA2328504A1 (de) |
| DE (1) | DE69942742D1 (de) |
| IL (1) | IL139700A (de) |
| WO (1) | WO1999065523A1 (de) |
Families Citing this family (31)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8038994B2 (en) | 1996-05-15 | 2011-10-18 | Quest Pharmatech Inc. | Combination therapy for treating disease |
| CA2328504A1 (en) * | 1998-06-15 | 1999-12-23 | Altarex Corp. | Immunotherapeutic composition and method for the treatment of prostate cancer |
| AU768515B2 (en) * | 1999-01-13 | 2003-12-18 | Igeneon Krebs-Immuntherapie Forschungs- Und Entwicklungs-Ag | Use of antibodies for anticancer vaccination |
| IL152747A0 (en) * | 2000-05-11 | 2003-06-24 | Altarex Inc | Therapeutic method and composition utilizing antigen-antibody complexation and presentation by dendritic cells |
| US8658773B2 (en) | 2011-05-02 | 2014-02-25 | Immunomedics, Inc. | Ultrafiltration concentration of allotype selected antibodies for small-volume administration |
| WO2003086041A2 (en) * | 2002-04-11 | 2003-10-23 | Altarex Medical Corporation | Binding agents and their use in targeting tumor cells |
| US20050271649A1 (en) * | 2002-10-17 | 2005-12-08 | Schultes Birgit C | Therapeutic adjuvant |
| US7902338B2 (en) | 2003-07-31 | 2011-03-08 | Immunomedics, Inc. | Anti-CD19 antibodies |
| GB0329146D0 (en) * | 2003-12-16 | 2004-01-21 | Glaxosmithkline Biolog Sa | Vaccine |
| CA2523032A1 (en) | 2005-10-07 | 2007-04-07 | Immunovaccine Technologies Inc. | Vaccines for cancer therapy |
| US20080095790A1 (en) * | 2006-10-24 | 2008-04-24 | Perambakam Supriya M | Methods of Treating Prostate Cancer |
| JP5731198B2 (ja) | 2007-09-27 | 2015-06-10 | イムノバクシーン・テクノロジーズ・インコーポレイテッドImmunovaccine Technologies Inc. | インビボでのポリヌクレオチドの送達のための連続疎水相を含む担体におけるリポソームの使用 |
| US20100209452A1 (en) * | 2007-10-03 | 2010-08-19 | Immunovaccine Technologies, Inc | Compositions comprising an antigen, an amphipathic compound and a hydrophobic carrier, and uses thereof |
| EP2331130B1 (de) * | 2008-04-09 | 2018-02-14 | Oncoquest Inc. | Ige-antikörper zur behandlung von krebs |
| BRPI0913612B8 (pt) | 2008-06-05 | 2021-05-25 | Immunovaccine Technologies Inc | composição injetável de vacina, método para obter a composição e uso da composição |
| GB0811567D0 (en) * | 2008-06-24 | 2008-07-30 | Cytosystems Ltd | Assay |
| PT3903829T (pt) | 2009-02-13 | 2023-06-02 | Immunomedics Inc | Imunoconjugados com uma ligação intracelular clivável |
| WO2011034660A1 (en) | 2009-09-16 | 2011-03-24 | Immunomedics, Inc. | Class i anti-cea antibodies and uses thereof |
| ES2978177T3 (es) | 2009-12-02 | 2024-09-06 | Immunomedics Inc | Combinación de radio inmunoterapia y conjugados anticuerpo-fármaco para mejorar la terapia contra el cáncer |
| US9023802B2 (en) * | 2009-12-14 | 2015-05-05 | Immatics Biotechnologies Gmbh | HLA-binding peptides derived from prostate-associated antigenic molecules and methods of use thereof |
| US10105435B2 (en) | 2011-10-06 | 2018-10-23 | Immunovaccine Technologies Inc. | Liposome compositions comprising an adjuvant that activates or increases the activity of TLR2 and uses thereof |
| AU2013302696B9 (en) | 2012-08-14 | 2018-08-09 | Ibc Pharmaceuticals, Inc. | T-cell redirecting bispecific antibodies for treatment of disease |
| CA3177936A1 (en) | 2012-12-13 | 2014-06-19 | Immunomedics, Inc. | Dosages of immunoconjugates of antibodies and sn-38 for improved efficacy and decreased toxicity |
| WO2015126548A1 (en) | 2014-02-21 | 2015-08-27 | Ibc Pharmaceuticals, Inc. | Disease therapy by inducing immune response to trop-2 expressing cells |
| CN106029098A (zh) | 2014-02-25 | 2016-10-12 | 免疫医疗公司 | 人源化rfb4抗cd22抗体 |
| US9580495B2 (en) | 2014-06-24 | 2017-02-28 | Immunomedics, Inc. | Anti-histone therapy for vascular necrosis in severe glomerulonephritis |
| SI3204018T1 (sl) | 2014-10-07 | 2021-11-30 | Immunomedics, Inc. | Neoadjuvantna uporaba konjugatov protitelo-zdravilo |
| WO2016172427A1 (en) | 2015-04-22 | 2016-10-27 | Immunomedics, Inc. | Isolation, detection, diagnosis and/or characterization of circulating trop-2-positive cancer cells |
| EP3313443B9 (de) | 2015-06-25 | 2023-10-04 | Immunomedics, Inc. | Kombination von anti-hla-dr- oder anti-trop-2-antikörpern mit mikrotubuli-inhibitoren, parp-inhibitoren, bruton-kinase-inhibitoren oder phosphoinositol-3-kinase-inhibitoren zur signifikanten verbesserung des therapeutischen ergebnisses bei krebs |
| SI3316885T1 (sl) | 2015-07-01 | 2021-09-30 | Immunomedics, Inc. | Imunokonjugati protitelo-SN-38 z linkerjem CL2A |
| WO2022239720A1 (ja) | 2021-05-10 | 2022-11-17 | 公益財団法人川崎市産業振興財団 | 抗原への結合親和性を低減させた抗体 |
Family Cites Families (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3865689A (en) * | 1972-11-09 | 1975-02-11 | Hoffmann La Roche | Method of producing carcinoembryonic antigens |
| US4446122A (en) | 1979-12-28 | 1984-05-01 | Research Corporation | Purified human prostate antigen |
| US4331647A (en) * | 1980-03-03 | 1982-05-25 | Goldenberg Milton David | Tumor localization and therapy with labeled antibody fragments specific to tumor-associated markers |
| US5053224A (en) * | 1983-11-07 | 1991-10-01 | Hilary Koprowski | Induction of antibody response to solid tumors with anti-idiotype antibodies |
| EP0229830B1 (de) | 1985-07-05 | 1994-11-09 | Puget Sound Blood Center and Program | Verfahren zum reduzieren der immunogenizität und zum induzieren immunologischer toleranz |
| EP0234122A3 (de) | 1986-02-21 | 1989-03-22 | Oncogen Limited Partnership | Tumortherapie mit biologisch aktiven Anti-Tumor-Antikörpern |
| AU613590B2 (en) | 1986-11-19 | 1991-08-08 | Bristol-Myers Squibb Company | Hybridomas producing monoclonal antibodies to new mucin epitopes |
| US5059680A (en) | 1986-11-24 | 1991-10-22 | Centocor, Inc. | Method of isolating ca 125 antigen |
| US5683674A (en) | 1987-01-07 | 1997-11-04 | Imperial Cancer Research Technology Ltd. | Antibody against human mucin core protein and method of preparing and using same |
| US4859449A (en) | 1987-09-14 | 1989-08-22 | Center For Molecular Medicine And Immunology | Modified antibodies for enhanced hepatocyte clearance |
| GB8728856D0 (en) | 1987-12-10 | 1988-01-27 | Bradwell A R | Tumour-locating agents & method of locating tumours |
| ATE145727T1 (de) | 1989-09-15 | 1996-12-15 | Genetic Systems Corp | Hybridoma ct43, das ein antikörper gegen ein mucinepitop von darmkrebs erzeugt |
| US5165922A (en) * | 1990-05-22 | 1992-11-24 | Bristol-Myers Squibb Company | Synergistic tumor therapy with combinations of biologically active anti-tumor antibodies and chemotherapy |
| DE4133791A1 (de) | 1991-10-11 | 1993-04-15 | Behringwerke Ag | Monoklonale antikoerper gegen tumorassoziierte antigene, verfahren zu ihrer herstellung und ihre verwendung |
| EP0652014A1 (de) * | 1993-11-10 | 1995-05-10 | National Institute Of Immunology | Behandlung von Prostatahypertrophie |
| US5773292A (en) | 1995-06-05 | 1998-06-30 | Cornell University | Antibodies binding portions, and probes recognizing an antigen of prostate epithelial cells but not antigens circulating in the blood |
| US6143509A (en) * | 1996-02-06 | 2000-11-07 | Abbott Laboratories | Prostate specific antigen peptides and uses thereof |
| GB9606228D0 (en) | 1996-03-25 | 1996-05-29 | Secr Defence | Apparatus for matrix coating fibres with metal vapour |
| WO1998010292A1 (en) | 1996-09-06 | 1998-03-12 | Centocor, Inc. | Monoclonal antibodies specific for prostate specific antigen and methods of detecting prostate specific antigen |
| CA2328504A1 (en) * | 1998-06-15 | 1999-12-23 | Altarex Corp. | Immunotherapeutic composition and method for the treatment of prostate cancer |
-
1999
- 1999-06-15 CA CA002328504A patent/CA2328504A1/en not_active Abandoned
- 1999-06-15 AT AT99925216T patent/ATE480566T1/de not_active IP Right Cessation
- 1999-06-15 IL IL13970099A patent/IL139700A/xx not_active IP Right Cessation
- 1999-06-15 EP EP99925216A patent/EP1085905B1/de not_active Expired - Lifetime
- 1999-06-15 WO PCT/IB1999/001115 patent/WO1999065523A1/en not_active Ceased
- 1999-06-15 AU AU41594/99A patent/AU768002B2/en not_active Ceased
- 1999-06-15 US US09/332,866 patent/US6881405B2/en not_active Expired - Lifetime
- 1999-06-15 DE DE69942742T patent/DE69942742D1/de not_active Expired - Lifetime
- 1999-06-15 JP JP2000554401A patent/JP2002518347A/ja active Pending
-
2004
- 2004-10-14 US US10/966,789 patent/US7579445B2/en not_active Expired - Fee Related
-
2007
- 2007-10-31 US US11/981,715 patent/US20090220493A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| WO1999065523A1 (en) | 1999-12-23 |
| US20090220493A1 (en) | 2009-09-03 |
| JP2002518347A (ja) | 2002-06-25 |
| EP1085905B1 (de) | 2010-09-08 |
| CA2328504A1 (en) | 1999-12-23 |
| AU768002B2 (en) | 2003-11-27 |
| IL139700A (en) | 2005-09-25 |
| US6881405B2 (en) | 2005-04-19 |
| AU4159499A (en) | 2000-01-05 |
| US20050202018A1 (en) | 2005-09-15 |
| DE69942742D1 (de) | 2010-10-21 |
| US20020136715A1 (en) | 2002-09-26 |
| US7579445B2 (en) | 2009-08-25 |
| IL139700A0 (en) | 2002-02-10 |
| EP1085905A1 (de) | 2001-03-28 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |