ATE481386T1 - Neue 3-aza-spiroä5.5üundec-8-en derivate und deren verwendung als inhibitoren der wiederaufnahme von monoaminneurotransmittern - Google Patents
Neue 3-aza-spiroä5.5üundec-8-en derivate und deren verwendung als inhibitoren der wiederaufnahme von monoaminneurotransmitternInfo
- Publication number
- ATE481386T1 ATE481386T1 AT06763929T AT06763929T ATE481386T1 AT E481386 T1 ATE481386 T1 AT E481386T1 AT 06763929 T AT06763929 T AT 06763929T AT 06763929 T AT06763929 T AT 06763929T AT E481386 T1 ATE481386 T1 AT E481386T1
- Authority
- AT
- Austria
- Prior art keywords
- aza
- inhibitors
- reuppost
- derivatives
- new
- Prior art date
Links
- 239000003112 inhibitor Substances 0.000 title abstract 2
- 239000002858 neurotransmitter agent Substances 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 2
- MBYQFWNVCJNILC-UHFFFAOYSA-N 3-azaspiro[5.5]undec-9-ene Chemical class C1CNCCC21CC=CCC2 MBYQFWNVCJNILC-UHFFFAOYSA-N 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 230000001561 neurotransmitter reuptake Effects 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 238000002560 therapeutic procedure Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
- C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
- C07D221/20—Spiro-condensed ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Pain & Pain Management (AREA)
- Psychiatry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DKPA200500959 | 2005-06-28 | ||
| US69467905P | 2005-06-29 | 2005-06-29 | |
| PCT/EP2006/063633 WO2007000464A1 (en) | 2005-06-28 | 2006-06-28 | Novel 3-aza-spiro[5.5]undec-8-ene derivatives and their use as monoamine neurotransmitter re-uptake inhibitors |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE481386T1 true ATE481386T1 (de) | 2010-10-15 |
Family
ID=40338741
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT06763929T ATE481386T1 (de) | 2005-06-28 | 2006-06-28 | Neue 3-aza-spiroä5.5üundec-8-en derivate und deren verwendung als inhibitoren der wiederaufnahme von monoaminneurotransmittern |
Country Status (3)
| Country | Link |
|---|---|
| US (1) | US8093388B2 (de) |
| AT (1) | ATE481386T1 (de) |
| DE (1) | DE602006016945D1 (de) |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4041174A (en) * | 1974-08-16 | 1977-08-09 | Rom-Amer Pharmaceuticals, Ltd. | Method of treating depression |
| NZ321970A (en) | 1995-11-02 | 2000-02-28 | Neurosearch As | Fused tropane-derivatives as neurotransmitter reuptake inhibitors |
| JP3238414B2 (ja) * | 1996-02-22 | 2001-12-17 | ニューロサーチ・アクティーゼルスカブ | トロパン―誘導体、その製造方法及びその使用方法 |
-
2006
- 2006-06-28 AT AT06763929T patent/ATE481386T1/de not_active IP Right Cessation
- 2006-06-28 DE DE602006016945T patent/DE602006016945D1/de active Active
- 2006-06-28 US US11/922,929 patent/US8093388B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| US20090036477A1 (en) | 2009-02-05 |
| US8093388B2 (en) | 2012-01-10 |
| DE602006016945D1 (de) | 2010-10-28 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |