ATE483717T1 - Tricyclische stickstoffhaltige verbindungen als antibakterielle wirkstoffe - Google Patents

Tricyclische stickstoffhaltige verbindungen als antibakterielle wirkstoffe

Info

Publication number
ATE483717T1
ATE483717T1 AT08749580T AT08749580T ATE483717T1 AT E483717 T1 ATE483717 T1 AT E483717T1 AT 08749580 T AT08749580 T AT 08749580T AT 08749580 T AT08749580 T AT 08749580T AT E483717 T1 ATE483717 T1 AT E483717T1
Authority
AT
Austria
Prior art keywords
containing compounds
antibacterial actives
tricyclic nitrogen
tricyclic
nitrogen
Prior art date
Application number
AT08749580T
Other languages
English (en)
Inventor
David Davies
Ilaria Giordano
Alan Hennessy
Neil Pearson
Original Assignee
Glaxo Group Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=39580226&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATE483717(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from GB0707705A external-priority patent/GB0707705D0/en
Priority claimed from GB0720569A external-priority patent/GB0720569D0/en
Priority claimed from GB0805311A external-priority patent/GB0805311D0/en
Application filed by Glaxo Group Ltd filed Critical Glaxo Group Ltd
Application granted granted Critical
Publication of ATE483717T1 publication Critical patent/ATE483717T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
    • C07D471/16—Peri-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A61P31/06—Antibacterial agents for tuberculosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains three hetero rings
    • C07D487/16—Peri-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Communicable Diseases (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Public Health (AREA)
  • Virology (AREA)
  • Pulmonology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
AT08749580T 2007-04-20 2008-04-16 Tricyclische stickstoffhaltige verbindungen als antibakterielle wirkstoffe ATE483717T1 (de)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
GB0707705A GB0707705D0 (en) 2007-04-20 2007-04-20 Compounds
GB0720569A GB0720569D0 (en) 2007-10-19 2007-10-19 Compounds
GB0805311A GB0805311D0 (en) 2008-03-20 2008-03-20 Compounds
PCT/EP2008/054621 WO2008128942A1 (en) 2007-04-20 2008-04-16 Tricyclic nitrogen containing compounds as antibacterial agents

Publications (1)

Publication Number Publication Date
ATE483717T1 true ATE483717T1 (de) 2010-10-15

Family

ID=39580226

Family Applications (1)

Application Number Title Priority Date Filing Date
AT08749580T ATE483717T1 (de) 2007-04-20 2008-04-16 Tricyclische stickstoffhaltige verbindungen als antibakterielle wirkstoffe

Country Status (31)

Country Link
US (1) US8389524B2 (de)
EP (1) EP2137196B1 (de)
JP (1) JP5389013B2 (de)
KR (1) KR101567096B1 (de)
CN (1) CN101687887B (de)
AR (1) AR066111A1 (de)
AT (1) ATE483717T1 (de)
AU (1) AU2008240764C1 (de)
BR (1) BRPI0810064B8 (de)
CA (1) CA2684659C (de)
CL (1) CL2008001122A1 (de)
CO (1) CO6251368A2 (de)
CR (2) CR11123A (de)
CY (1) CY1111248T1 (de)
DE (1) DE602008002912D1 (de)
DK (1) DK2137196T3 (de)
DO (1) DOP2009000240A (de)
EA (1) EA015821B1 (de)
HR (1) HRP20100574T1 (de)
IL (1) IL201204A0 (de)
MA (1) MA31324B1 (de)
MX (1) MX2009011317A (de)
MY (1) MY149347A (de)
NZ (1) NZ579877A (de)
PE (1) PE20090274A1 (de)
PL (1) PL2137196T3 (de)
PT (1) PT2137196E (de)
SI (1) SI2137196T1 (de)
TW (1) TWI431006B (de)
UY (1) UY31038A1 (de)
WO (1) WO2008128942A1 (de)

Families Citing this family (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2006335042A1 (en) * 2005-10-21 2007-07-19 Glaxo Group Limited Compounds
EP1847543A1 (de) 2006-04-19 2007-10-24 Boehringer Ingelheim Pharma GmbH & Co. KG Dihydrothienopyrimidine zur Behandlung von entzündlichen Erkrankungen
GB0608263D0 (en) 2006-04-26 2006-06-07 Glaxo Group Ltd Compounds
ATE537175T1 (de) 2007-10-19 2011-12-15 Boehringer Ingelheim Int Neue piperazino-dihydrothienopyrimidin-derivate
ES2524910T3 (es) * 2007-10-19 2014-12-15 Boehringer Ingelheim International Gmbh Piperidino-dihidrotienopirimidinas sustituidas
JP5341899B2 (ja) 2007-10-19 2013-11-13 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング ヘテロ環置換ピペラジノ−ジヒドロチエノピリミジン
US8349828B2 (en) 2008-02-20 2013-01-08 Actelion Pharmaceuticals Ltd. Azatricyclic antibiotic compounds
US20110071155A1 (en) * 2008-05-23 2011-03-24 Carlos Alemparte-Gallardo Tricyclic Nitrogen Containing Compounds And Their Use As Antibacterials
MX2010012732A (es) * 2008-05-23 2010-12-07 Glaxo Group Ltd Compuestos que contienen nitrogeno triciclico y su uso como antibacterianos.
PT2344495E (pt) 2008-10-07 2015-04-01 Actelion Pharmaceuticals Ltd Compostos antibióticos de oxazolidinona tricíclica
EP2352734A1 (de) 2008-10-17 2011-08-10 Glaxo Group Limited Als antibakterielle mittel verwendete tricyclische stickstoffverbindungen
EP2387567B1 (de) 2009-01-14 2014-06-11 The Salk Institute for Biological Studies Gegen amyloidkrankheiten schützende verbindungen
AR076222A1 (es) 2009-04-09 2011-05-26 Actelion Pharmaceuticals Ltd Derivados 2-hidroxietil-1h-quinolin-ona y sus analogos azaisotericos con actividad antibacteriana y composiciones farmaceuticas que los contienen
TW201130854A (en) 2009-12-22 2011-09-16 Bayer Schering Pharma Ag Pyridinone derivatives and pharmaceutical compositions thereof
WO2011140183A1 (en) * 2010-05-04 2011-11-10 Alkermes, Inc. Process for synthesizing oxidized lactam compounds
US9802954B2 (en) 2011-08-24 2017-10-31 Boehringer Ingelheim International Gmbh Piperidino-dihydrothienopyrimidine sulfoxides and their use for treating COPD and asthma
US20130059866A1 (en) 2011-08-24 2013-03-07 Boehringer Ingelheim International Gmbh Novel piperidino-dihydrothienopyrimidine sulfoxides and their use for treating copd and asthma
CN103113291B (zh) * 2013-02-04 2015-03-04 浙江大学 一种3位烯基吡啶衍生物的合成方法
JP6453216B2 (ja) * 2013-07-23 2019-01-16 エーザイ・アール・アンド・ディー・マネジメント株式会社 ヘテロ縮合環化合物
EP3639824A1 (de) * 2014-08-22 2020-04-22 GlaxoSmithKline Intellectual Property Development Limited Tricyclische stickstoffhaltige verbindungen zur behandlung einer infektion mit neisseria gonorrhoea
FI3474846T3 (fi) * 2016-06-22 2023-02-16 Univ Vanderbilt Muskariinisen asetyylikoliinireseptorin m4 positiiviset allosteeriset modulaattorit
EP3612513A4 (de) 2017-04-17 2020-09-30 Ohio State Innovation Foundation Typ-ii-topoisomerase-inhibitoren und verfahren zur herstellung und verwendung davon
JP2022528890A (ja) * 2019-04-03 2022-06-16 グラクソスミスクライン、インテレクチュアル、プロパティー、ディベロップメント、リミテッド 細菌性尿路感染症の治療に使用するためのゲポチダシン
WO2021004910A1 (en) 2019-07-05 2021-01-14 Glaxosmithkline Intellectual Property Development Limited Combination for the treatment of infections caused by mycoplasma genitalium
EP4125905B1 (de) 2020-04-02 2024-12-25 GlaxoSmithKline Intellectual Property Development Limited Schema zur behandlung einer neisseria gonorrhoeae-infektion mit gepotidacin
EP4143188A1 (de) * 2020-04-29 2023-03-08 GlaxoSmithKline Intellectual Property Development Limited Kristalline formen von gepotidacin
CN111494241B (zh) * 2020-06-01 2023-03-24 湖北洁世达环保科技有限公司 一种纸巾柔润保湿液
WO2022167515A1 (en) 2021-02-05 2022-08-11 Glaxosmithkline Intellectual Property Development Limited Oral solid dose formulations
US20250099535A1 (en) 2022-01-21 2025-03-27 Glaxosmithkline Intellectual Property Development Limited Gepotidacin and vancomycin for use in the treatment of an infection caused by staphylococcus saprophyticus
EP4316463A1 (de) 2022-08-02 2024-02-07 GlaxoSmithKline Intellectual Property Development Limited Neuartige formulierung
WO2024068524A1 (en) 2022-09-26 2024-04-04 Glaxosmithkline Intellectual Property Development Limited Gepotidacin for use in the treatment of bacterial prostatitis

Family Cites Families (66)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6403610B1 (en) * 1999-09-17 2002-06-11 Aventis Pharma S.A. Quinolylpropylpiperidine derivatives, their preparation and the compositions which comprise them
US6525049B2 (en) * 2000-07-05 2003-02-25 Pharmacia & Upjohn Company Pyrroloquinolones as antiviral agents
US6624159B2 (en) * 2000-07-12 2003-09-23 Pharmacia & Upjohn Company Heterocycle carboxamides as antiviral agents
IL154107A0 (en) * 2000-07-26 2003-07-31 Smithkline Beecham Plc Aminopiperidine quinolines and their azaisosteric analogues with antibacterial activity
US6603005B2 (en) * 2000-11-15 2003-08-05 Aventis Pharma S.A. Heterocyclylalkylpiperidine derivatives, their preparation and compositions containing them
GB0031088D0 (en) * 2000-12-20 2001-01-31 Smithkline Beecham Plc Medicaments
WO2002050036A1 (en) * 2000-12-21 2002-06-27 Ciba Speciality Chemicals Holding Inc. Crystalline forms of cerivastatin sodium
GB0101577D0 (en) * 2001-01-22 2001-03-07 Smithkline Beecham Plc Compounds
US6602884B2 (en) * 2001-03-13 2003-08-05 Aventis Pharma S.A. Quinolylpropylpiperidine derivatives, their preparation, and compositions containing them
GB0112836D0 (en) * 2001-05-25 2001-07-18 Smithkline Beecham Plc Medicaments
GB0112834D0 (en) * 2001-05-25 2001-07-18 Smithkline Beecham Plc Medicaments
GB0118238D0 (en) * 2001-07-26 2001-09-19 Smithkline Beecham Plc Medicaments
WO2003048081A2 (en) * 2001-12-04 2003-06-12 Bristol-Myers Squibb Company Glycinamides as factor xa inhibitors
AU2003239302A1 (en) * 2002-01-29 2003-09-02 Glaxo Group Limited Aminopiperidine compounds, process for their preparation, and pharmaceutical compositions containing them
WO2003064421A1 (en) 2002-01-29 2003-08-07 Glaxo Group Limited Aminopiperidine derivatives
TW200406413A (en) * 2002-06-26 2004-05-01 Glaxo Group Ltd Compounds
TW200409637A (en) * 2002-06-26 2004-06-16 Glaxo Group Ltd Compounds
GB0217294D0 (en) * 2002-07-25 2002-09-04 Glaxo Group Ltd Medicaments
FR2844270B1 (fr) * 2002-09-11 2006-05-19 Aventis Pharma Sa Derives de la quinolyl propyl piperidine, leur procede et intermediaires de preparation et les compositions qui les contiennent
FR2844268B1 (fr) * 2002-09-11 2004-10-22 Aventis Pharma Sa Derives de la quinolyl propyl piperidine, leurs procedes et intermediaires de preparation et les compositions qui les contiennent
BR0315221A (pt) * 2002-10-10 2005-08-23 Morphochem Ag Komb Chemie Compostos com atividade antibacteriana
AU2003303956A1 (en) * 2002-11-05 2004-11-23 Smithkline Beecham Corporation Antibacterial agents
AU2003291227A1 (en) * 2002-11-05 2004-06-07 Smithkline Beecham Corporation Antibacterial agents
TW200427688A (en) * 2002-12-18 2004-12-16 Glaxo Group Ltd Antibacterial agents
TW200507841A (en) * 2003-03-27 2005-03-01 Glaxo Group Ltd Antibacterial agents
US7232833B2 (en) * 2003-03-28 2007-06-19 Novexel 4-substituted quinoline derivatives, method and intermediates for their preparation and pharmaceutical compositions containing them
DE10316081A1 (de) * 2003-04-08 2004-10-21 Morphochem AG Aktiengesellschaft für kombinatorische Chemie Neue Verbindungen mit antibakterieller Aktivität
US7348434B2 (en) * 2003-08-08 2008-03-25 Antony Bigot 4-substituted quinoline derivatives, method and intermediates for their preparation and pharmaceutical compositions containing them
FR2867472B1 (fr) 2004-03-12 2008-07-18 Aventis Pharma Sa Derives de quinoleines-4-substituees, leurs procede et intermediaires de preparation et les compositions pharmaceutiques qui les contiennent
EP1796466A4 (de) * 2004-06-15 2009-09-02 Glaxo Group Ltd Antibakterielle mittel
FR2872164B1 (fr) * 2004-06-29 2006-11-17 Aventis Pharma Sa Derives de quinoleines-4-substituees, leur procede et intermediaires de preparation et les compositions pharmaceutiques qui les contiennent
EP1773831A1 (de) 2004-07-08 2007-04-18 Glaxo Group Limited Antibakterielle mittel
JP2008505926A (ja) * 2004-07-09 2008-02-28 グラクソ　グループ　リミテッド 抗細菌剤
EP1773343A4 (de) * 2004-07-13 2009-05-13 Glaxo Group Ltd Antibakterielle mittel
US20070270417A1 (en) 2004-07-22 2007-11-22 Glaxo Group Limited Antibacterial Agents
WO2006017468A2 (en) * 2004-08-02 2006-02-16 Glaxo Group Limited Antibacterial agents
JP2008509222A (ja) * 2004-08-09 2008-03-27 グラクソ グループ リミテッド 抗菌剤
DE102004041163A1 (de) * 2004-08-25 2006-03-02 Morphochem Aktiengesellschaft für kombinatorische Chemie Neue Verbindungen mit antibakterieller Aktivität
CA2580621A1 (en) 2004-09-24 2006-03-30 Actelion Pharmaceuticals Ltd New bicyclic antibiotics
CA2581057A1 (en) * 2004-10-05 2006-04-13 Actelion Pharmaceuticals Ltd New piperidine antibiotics
JP5314244B2 (ja) 2004-10-27 2013-10-16 富山化学工業株式会社 新規な含窒素複素環化合物およびその塩
JP2008528588A (ja) * 2005-01-25 2008-07-31 グラクソ グループ リミテッド 抗菌剤
US7709472B2 (en) * 2005-01-25 2010-05-04 Glaxo Group Limited Antibacterial agents
EP1846411A4 (de) * 2005-01-25 2010-08-04 Glaxo Group Ltd Antibakterielle wirkstoffe
WO2006081264A1 (en) * 2005-01-25 2006-08-03 Glaxo Group Limited Antibacterial agents
JP2008528586A (ja) * 2005-01-25 2008-07-31 グラクソ グループ リミテッド 抗菌剤
WO2006099884A1 (en) 2005-03-24 2006-09-28 Actelion Percurex Ag Beta-aminoalcohol antibiotics
US7842810B2 (en) * 2005-03-31 2010-11-30 Janssen Pharmaceutica, Nv Bicyclic pyrazole compounds as antibacterial agents
WO2006125974A1 (en) * 2005-05-24 2006-11-30 Astrazeneca Ab Aminopiperidine quinolines and their azaisosteric analogues with antibacterial activity
JP2008542258A (ja) * 2005-05-25 2008-11-27 アクテリオン ファーマシューティカルズ リミテッド 新規抗生物質誘導体
MY150958A (en) * 2005-06-16 2014-03-31 Astrazeneca Ab Compounds for the treatment of multi-drug resistant bacterial infections
EP1900732A4 (de) 2005-06-24 2009-11-18 Toyama Chemical Co Ltd Neue nitrogenierte heterocyclische verbindung und salz davon
AU2006335042A1 (en) * 2005-10-21 2007-07-19 Glaxo Group Limited Compounds
ES2344523T3 (es) * 2005-12-22 2010-08-30 Glaxo Group Limited Compuestos heterociclicos, su preparacion y su uso como agentes antibacterianos.
EP2007377A4 (de) * 2006-04-06 2011-08-17 Glaxo Group Ltd Antibakterielle wirkstoffe
ATE481406T1 (de) * 2006-04-06 2010-10-15 Glaxo Group Ltd Pyrrolochinoxalinonderivate als antibakterielle mittel
GB0608263D0 (en) * 2006-04-26 2006-06-07 Glaxo Group Ltd Compounds
JP2009539807A (ja) * 2006-06-09 2009-11-19 グラクソ グループ リミテッド 抗菌薬としての置換１−メチル−１ｈ−キノリン−２−オンおよび１−メチル−１ｈ−１，５−ナフチリジン−２−オン
GB0613208D0 (en) * 2006-07-03 2006-08-09 Glaxo Group Ltd Compounds
EP1992628A1 (de) 2007-05-18 2008-11-19 Glaxo Group Limited Derivate und Analoge von N-Ethylquinolonen und N-Ethylazaquinolonen
GB0705672D0 (en) * 2007-03-23 2007-05-02 Glaxo Group Ltd Compounds
EP1980251A1 (de) * 2007-04-13 2008-10-15 Glaxo Group Limited Pyrrolo[3,2,1-ij]quinolin-4-on Derivate zur Behandlung der Tuberkulose
GB0707706D0 (en) * 2007-04-20 2007-05-30 Glaxo Group Ltd Compounds
GB0707708D0 (en) * 2007-04-20 2007-05-30 Glaxo Group Ltd Compounds
EP2005995A1 (de) * 2007-06-22 2008-12-24 Glaxo Group Limited Heterocyclische Verbindungen für die Behandlung von Tuberkulose
GB0800367D0 (en) * 2008-01-09 2008-02-20 Glaxo Group Ltd Compounds

Also Published As

Publication number Publication date
CA2684659A1 (en) 2008-10-30
BRPI0810064B1 (pt) 2021-03-30
CY1111248T1 (el) 2015-06-11
CR20150586A (es) 2016-04-04
CN101687887A (zh) 2010-03-31
PT2137196E (pt) 2010-12-16
AU2008240764A1 (en) 2008-10-30
DE602008002912D1 (de) 2010-11-18
AU2008240764B2 (en) 2011-04-07
BRPI0810064B8 (pt) 2021-05-25
EA015821B1 (ru) 2011-12-30
TW200848420A (en) 2008-12-16
AR066111A1 (es) 2009-07-22
EP2137196A1 (de) 2009-12-30
UY31038A1 (es) 2008-11-28
CR11123A (es) 2010-03-08
JP2010524884A (ja) 2010-07-22
CA2684659C (en) 2015-11-24
SI2137196T1 (sl) 2011-01-31
TWI431006B (zh) 2014-03-21
CO6251368A2 (es) 2011-02-21
DOP2009000240A (es) 2009-12-31
BRPI0810064A2 (pt) 2019-08-27
PL2137196T3 (pl) 2011-03-31
AU2008240764C1 (en) 2011-10-20
US20100137282A1 (en) 2010-06-03
MA31324B1 (fr) 2010-04-01
KR20100017133A (ko) 2010-02-16
EA200970987A1 (ru) 2010-04-30
DK2137196T3 (da) 2011-01-10
WO2008128942A1 (en) 2008-10-30
PE20090274A1 (es) 2009-04-03
KR101567096B1 (ko) 2015-11-06
EP2137196B1 (de) 2010-10-06
CN101687887B (zh) 2012-08-29
HRP20100574T1 (hr) 2010-12-31
IL201204A0 (en) 2010-05-17
NZ579877A (en) 2011-09-30
MY149347A (en) 2013-08-30
HK1138000A1 (en) 2010-08-13
JP5389013B2 (ja) 2014-01-15
MX2009011317A (es) 2009-11-05
CL2008001122A1 (es) 2008-10-24
US8389524B2 (en) 2013-03-05

Similar Documents

Publication Publication Date Title
ATE483717T1 (de) Tricyclische stickstoffhaltige verbindungen als antibakterielle wirkstoffe
ATE499363T1 (de) Organische verbindungen
DK2240490T3 (da) Organiske forbindelser
BRPI0817434A2 (pt) Composto orgânicos
ATE507225T1 (de) Antibakterielle polycyclische harnstoffverbindungen
ATE540954T1 (de) Aminoheterocyclische verbindungen
BRPI0915374A2 (pt) Novos compostos tricíclicos
SMT201500117B (it) Composti antibatterici
ATE486862T1 (de) Organische verbindungen
BRPI0815067A2 (pt) Compostos de biciclotactama substituída
BRPI0718874A2 (pt) Compostos orgânicos
NO20084803L (no) organiske forbindelser
BRPI0718478A2 (pt) Compostos orgânicos
BRPI0922351A2 (pt) compostos orgânicos
BRPI0922700A2 (pt) Compostos orgânicos
BRPI0922808A2 (pt) compostos orgânicos
BRPI0922809A2 (pt) compostos orgânicos
BRPI0922348A2 (pt) Compostos orgânicos
BRPI0922131A2 (pt) Compostos orgânicos
BRPI0913966A2 (pt) compostos orgânicos
BRPI0914698A2 (pt) compostos orgânicos
BRPI0909417A2 (pt) compostos orgânicos
BRPI0915018A2 (pt) compostos orgânicos
EP2312950A4 (de) Verbindungen als kinasehemmer
BRPI0916995A2 (pt) compostos orgânicos

Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification

Ref document number: 2137196

Country of ref document: EP