ATE483823T1 - Methode zur detektion und beobachtung von krankheiten durch analyse von an den zellen gebundenen nukleinsäuren - Google Patents
Methode zur detektion und beobachtung von krankheiten durch analyse von an den zellen gebundenen nukleinsäurenInfo
- Publication number
- ATE483823T1 ATE483823T1 AT04786212T AT04786212T ATE483823T1 AT E483823 T1 ATE483823 T1 AT E483823T1 AT 04786212 T AT04786212 T AT 04786212T AT 04786212 T AT04786212 T AT 04786212T AT E483823 T1 ATE483823 T1 AT E483823T1
- Authority
- AT
- Austria
- Prior art keywords
- nucleic acids
- cells
- cell
- cellular
- detecting
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 5
- 108020004707 nucleic acids Proteins 0.000 title abstract 5
- 150000007523 nucleic acids Chemical group 0.000 title abstract 5
- 102000039446 nucleic acids Human genes 0.000 title abstract 5
- 201000010099 disease Diseases 0.000 title abstract 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 title abstract 2
- 238000012544 monitoring process Methods 0.000 title abstract 2
- 210000004027 cell Anatomy 0.000 abstract 5
- 238000001514 detection method Methods 0.000 abstract 3
- 206010028980 Neoplasm Diseases 0.000 abstract 1
- 238000010222 PCR analysis Methods 0.000 abstract 1
- -1 PCR analysis Chemical class 0.000 abstract 1
- 208000006994 Precancerous Conditions Diseases 0.000 abstract 1
- 102000004142 Trypsin Human genes 0.000 abstract 1
- 108090000631 Trypsin Proteins 0.000 abstract 1
- 230000002159 abnormal effect Effects 0.000 abstract 1
- 238000011319 anticancer therapy Methods 0.000 abstract 1
- 238000003556 assay Methods 0.000 abstract 1
- 210000004369 blood Anatomy 0.000 abstract 1
- 239000008280 blood Substances 0.000 abstract 1
- 201000011510 cancer Diseases 0.000 abstract 1
- 230000001413 cellular effect Effects 0.000 abstract 1
- 210000003743 erythrocyte Anatomy 0.000 abstract 1
- 230000002068 genetic effect Effects 0.000 abstract 1
- 238000009396 hybridization Methods 0.000 abstract 1
- 210000000265 leukocyte Anatomy 0.000 abstract 1
- 238000007403 mPCR Methods 0.000 abstract 1
- 206010025482 malaise Diseases 0.000 abstract 1
- 230000007170 pathology Effects 0.000 abstract 1
- 230000035935 pregnancy Effects 0.000 abstract 1
- 230000035945 sensitivity Effects 0.000 abstract 1
- 239000012588 trypsin Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6806—Preparing nucleic acids for analysis, e.g. for polymerase chain reaction [PCR] assay
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
- C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Analytical Chemistry (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Biophysics (AREA)
- Physics & Mathematics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Immunology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Enzymes And Modification Thereof (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| RU2003125486/15A RU2249820C1 (ru) | 2003-08-18 | 2003-08-18 | Способ ранней диагностики заболеваний, связанных с нарушением функционирования генетического аппарата клетки |
| PCT/EP2004/009218 WO2005017197A2 (en) | 2003-08-18 | 2004-08-17 | Method for early detection and monitoring of diseases by analysis of cell-surface-bound nucleic acids |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE483823T1 true ATE483823T1 (de) | 2010-10-15 |
Family
ID=34192339
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT04786212T ATE483823T1 (de) | 2003-08-18 | 2004-08-17 | Methode zur detektion und beobachtung von krankheiten durch analyse von an den zellen gebundenen nukleinsäuren |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US20070020636A1 (de) |
| EP (1) | EP1658384B1 (de) |
| AT (1) | ATE483823T1 (de) |
| DE (1) | DE602004029477D1 (de) |
| RU (1) | RU2249820C1 (de) |
| WO (1) | WO2005017197A2 (de) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR20250002752A (ko) | 2007-07-23 | 2025-01-07 | 더 차이니즈 유니버시티 오브 홍콩 | 대규모 병렬 게놈 서열분석을 이용한 태아 염색체 이수성의 진단 방법 |
| US12180549B2 (en) | 2007-07-23 | 2024-12-31 | The Chinese University Of Hong Kong | Diagnosing fetal chromosomal aneuploidy using genomic sequencing |
| RU2348042C1 (ru) * | 2007-10-05 | 2009-02-27 | Автономная некоммерческая организация "Центр медицинских биотехнологий" | Способ диагностики онкологических заболеваний предстательной железы |
| US9892230B2 (en) | 2012-03-08 | 2018-02-13 | The Chinese University Of Hong Kong | Size-based analysis of fetal or tumor DNA fraction in plasma |
| US10364467B2 (en) | 2015-01-13 | 2019-07-30 | The Chinese University Of Hong Kong | Using size and number aberrations in plasma DNA for detecting cancer |
| CN113430264A (zh) * | 2020-03-23 | 2021-09-24 | 南京梅傲红清生物科技有限公司 | 红细胞核酸在鉴定肿瘤的突变类型中的应用 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3721400A1 (de) * | 1987-06-29 | 1989-01-12 | Viktor Dr Dr Med Balazs | Verfahren zur untersuchung einer azellularen biologischen fluessigkeit auf zellulare onkogen-dna bzw. deren fragmente |
| RU2164419C2 (ru) * | 1994-03-18 | 2001-03-27 | Мириад Дженетикс, Инк. | Ген mts, мутации данного гена и способы диагностики злокачественных опухолей с использованием последовательности гена mts |
| EP0929694A4 (de) * | 1996-03-15 | 2002-05-02 | Penn State Res Found | Nachweis von extrazellulärer tumor-assoziierter nukleinsäuren im blutplasma oder -serum mittels eines nukleinsäure-amplifizierungsverfahren |
| WO2002010392A2 (en) * | 2000-08-01 | 2002-02-07 | Oregon Health & Science University | Mammalian dna binding membrane-associated protein-encoding gene and uses |
-
2003
- 2003-08-18 RU RU2003125486/15A patent/RU2249820C1/ru not_active IP Right Cessation
-
2004
- 2004-08-17 WO PCT/EP2004/009218 patent/WO2005017197A2/en not_active Ceased
- 2004-08-17 DE DE602004029477T patent/DE602004029477D1/de not_active Expired - Lifetime
- 2004-08-17 EP EP04786212A patent/EP1658384B1/de not_active Expired - Lifetime
- 2004-08-17 AT AT04786212T patent/ATE483823T1/de active
-
2006
- 2006-03-28 US US10/576,005 patent/US20070020636A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| WO2005017197A3 (en) | 2005-04-21 |
| DE602004029477D1 (de) | 2010-11-18 |
| RU2003125486A (ru) | 2005-02-10 |
| EP1658384B1 (de) | 2010-10-06 |
| WO2005017197A2 (en) | 2005-02-24 |
| US20070020636A1 (en) | 2007-01-25 |
| RU2249820C1 (ru) | 2005-04-10 |
| EP1658384A2 (de) | 2006-05-24 |
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