ATE484580T1 - Neuer gen-cluster aus genen der pederin- biosynthese - Google Patents

Neuer gen-cluster aus genen der pederin- biosynthese

Info

Publication number: ATE484580T1
Authority: AT; Austria
Prior art keywords: pederin; gene cluster; new gene; biosynthesis genes; biosynthesis
Prior art date: 2001-11-22

Application number

AT02803403T

Other languages

English (en)

Inventor

Joern Piel

Original Assignee

Univ Bonn

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2001-11-22

Filing date

2002-11-21

Publication date

2010-10-15

2002-11-21 Application filed by Univ Bonn filed Critical Univ Bonn

2010-10-15 Application granted granted Critical

2010-10-15 Publication of ATE484580T1 publication Critical patent/ATE484580T1/de

Links

230000015572 biosynthetic process Effects 0.000 title abstract 3
MHRARRIFWSILEQ-UHFFFAOYSA-N Pederin Natural products COCC(CC1OC2C(NC(=O)C(O)C3(CC(=O)C(C)C(C)O3)OC)OCOC2C(OC)C1(C)C)OC MHRARRIFWSILEQ-UHFFFAOYSA-N 0.000 title abstract 2
108091008053 gene clusters Proteins 0.000 title abstract 2
ZNEZZONMADKYTB-VRCUBXEUSA-N pederin Chemical compound C1[C@@H](O)C(C)(C)[C@@H](C[C@@H](COC)OC)O[C@@H]1[C@H](OC)NC(=O)[C@@H](O)[C@]1(OC)O[C@H](C)[C@H](C)C(=C)C1 ZNEZZONMADKYTB-VRCUBXEUSA-N 0.000 title abstract 2
108090000623 proteins and genes Proteins 0.000 title abstract 2
108010030975 Polyketide Synthases Proteins 0.000 abstract 1
230000000259 anti-tumor effect Effects 0.000 abstract 1
238000010367 cloning Methods 0.000 abstract 1
150000001875 compounds Chemical class 0.000 abstract 1
229940000406 drug candidate Drugs 0.000 abstract 1
238000012163 sequencing technique Methods 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/52—Genes encoding for enzymes or proenzymes
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
- C12P17/02—Oxygen as only ring hetero atoms
- C12P17/06—Oxygen as only ring hetero atoms containing a six-membered hetero ring, e.g. fluorescein

Landscapes

Engineering & Computer Science (AREA)
Genetics & Genomics (AREA)
Life Sciences & Earth Sciences (AREA)
Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Wood Science & Technology (AREA)
Zoology (AREA)
Bioinformatics & Cheminformatics (AREA)
Biotechnology (AREA)
Biomedical Technology (AREA)
General Engineering & Computer Science (AREA)
Microbiology (AREA)
Biochemistry (AREA)
General Health & Medical Sciences (AREA)
Molecular Biology (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Physics & Mathematics (AREA)
Biophysics (AREA)
Plant Pathology (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Micro-Organisms Or Cultivation Processes Thereof (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Enzymes And Modification Thereof (AREA)

AT02803403T 2001-11-22 2002-11-21 Neuer gen-cluster aus genen der pederin- biosynthese ATE484580T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
EP01127395		2001-11-22
PCT/EP2002/013085 WO2003044186A2 (en)	2001-11-22	2002-11-21	Novel gene cluster of pederin biosynthesis genes

Publications (1)

Publication Number	Publication Date
ATE484580T1 true ATE484580T1 (de)	2010-10-15

Family

ID=8179274

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT02803403T ATE484580T1 (de)	2001-11-22	2002-11-21	Neuer gen-cluster aus genen der pederin- biosynthese

Country Status (7)

Country	Link
US (1)	US7771972B2 (de)
EP (1)	EP1448767B1 (de)
JP (1)	JP2005509435A (de)
AT (1)	ATE484580T1 (de)
AU (1)	AU2002356704A1 (de)
DE (1)	DE60237984D1 (de)
WO (1)	WO2003044186A2 (de)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB0423755D0 (en) *	2004-10-26	2004-11-24	Gene Bridges Gmbh	Methods for heterologus expression of secondary metabolites
RU2008107974A (ru) *	2005-08-02	2009-09-10	Фарма Мар, С.А. (Es)	Гены, участвующие в биосинтезе тиокоралина и его гетерологичном продуцировании
DE102008054660A1 (de) *	2008-12-15	2010-10-21	Rheinische Friedrich-Wilhelms-Universität Bonn	Polyketid Biosynthesegene
US8887388B2 (en)	2010-11-22	2014-11-18	Andrew Llc	Method for interconnecting a coaxial connector with a solid outer conductor coaxial cable
US8365404B2 (en)	2010-11-22	2013-02-05	Andrew Llc	Method for ultrasonic welding a coaxial cable to a coaxial connector
WO2017205387A1 (en) *	2016-05-23	2017-11-30	Northwestern University	Systems and methods for untargeted metabolomic screening
MX392144B (es) *	2017-03-17	2025-03-21	Pharma Mar Sa	Compuestos tipo pederina y el uso de los mismos en el tratatamiento de cáncer.

2002
- 2002-11-21 AT AT02803403T patent/ATE484580T1/de active
- 2002-11-21 US US10/496,377 patent/US7771972B2/en not_active Expired - Fee Related
- 2002-11-21 DE DE60237984T patent/DE60237984D1/de not_active Expired - Lifetime
- 2002-11-21 AU AU2002356704A patent/AU2002356704A1/en not_active Abandoned
- 2002-11-21 JP JP2003545809A patent/JP2005509435A/ja active Pending
- 2002-11-21 WO PCT/EP2002/013085 patent/WO2003044186A2/en not_active Ceased
- 2002-11-21 EP EP02803403A patent/EP1448767B1/de not_active Expired - Lifetime

Also Published As

Publication number	Publication date
WO2003044186A3 (en)	2004-01-29
JP2005509435A (ja)	2005-04-14
AU2002356704A1 (en)	2003-06-10
US20050118590A1 (en)	2005-06-02
DE60237984D1 (de)	2010-11-25
US7771972B2 (en)	2010-08-10
EP1448767A2 (de)	2004-08-25
EP1448767B1 (de)	2010-10-13
WO2003044186A2 (en)	2003-05-30

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