ATE485037T1 - Krebsbehandlung mittels fts und 2-deoxyglucose - Google Patents

Krebsbehandlung mittels fts und 2-deoxyglucose

Info

Publication number
ATE485037T1
ATE485037T1 AT06844276T AT06844276T ATE485037T1 AT E485037 T1 ATE485037 T1 AT E485037T1 AT 06844276 T AT06844276 T AT 06844276T AT 06844276 T AT06844276 T AT 06844276T AT E485037 T1 ATE485037 T1 AT E485037T1
Authority
AT
Austria
Prior art keywords
fts
deoxyglucose
cancer treatment
analogs
disclosed
Prior art date
Application number
AT06844276T
Other languages
English (en)
Inventor
Yoel Kloog
Liat Goldberg
Michael Brownstein
Original Assignee
Univ Ramot
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Ramot filed Critical Univ Ramot
Application granted granted Critical
Publication of ATE485037T1 publication Critical patent/ATE485037T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/192—Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid 
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7004—Monosaccharides having only carbon, hydrogen and oxygen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Saccharide Compounds (AREA)
AT06844276T 2005-11-28 2006-11-06 Krebsbehandlung mittels fts und 2-deoxyglucose ATE485037T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US74009605P 2005-11-28 2005-11-28
PCT/US2006/043325 WO2007064448A2 (en) 2005-11-28 2006-11-06 Cancer treatment using fts and 2-deoxyglucose

Publications (1)

Publication Number Publication Date
ATE485037T1 true ATE485037T1 (de) 2010-11-15

Family

ID=38016969

Family Applications (1)

Application Number Title Priority Date Filing Date
AT06844276T ATE485037T1 (de) 2005-11-28 2006-11-06 Krebsbehandlung mittels fts und 2-deoxyglucose

Country Status (5)

Country Link
US (1) US8278349B2 (de)
EP (1) EP1957060B1 (de)
AT (1) ATE485037T1 (de)
DE (1) DE602006017728D1 (de)
WO (1) WO2007064448A2 (de)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8088756B2 (en) 2004-08-18 2012-01-03 Concordia Pharmaceuticals, Inc. Methods and compositions for oral delivery of FTS
ATE485037T1 (de) 2005-11-28 2010-11-15 Univ Ramot Krebsbehandlung mittels fts und 2-deoxyglucose
WO2007101148A2 (en) * 2006-02-24 2007-09-07 Board Of Regents, The University Of Texas System Hexose compounds to treat cancer
EP2094260B1 (de) * 2006-12-19 2012-02-01 Ramot at Tel-Aviv University Ltd. Behandlung von lungenkrebs
CN102076865B (zh) 2008-05-02 2016-03-16 西雅图基因公司 用于制造核心岩藻糖基化降低的抗体和抗体衍生物的方法和组合物
WO2011056542A1 (en) * 2009-10-26 2011-05-12 Ramot At Tel-Aviv University Ltd. Cancer therapy with combinations of fts with hdac inhibitors
EP3513794A3 (de) 2010-08-05 2019-10-16 Seattle Genetics, Inc. Fucose-analoga für in-vivo-hemmung einer protein-fucosylierung
US9738614B2 (en) 2011-10-07 2017-08-22 Pisces Therapeutics, Llc Malignant and non-malignant disease treatment with Ras antagonists
WO2013052765A1 (en) 2011-10-07 2013-04-11 Pisces Therapeutics Llc Malignant and non-malignant disease treatment with ras antagonists
US10350228B2 (en) 2012-08-23 2019-07-16 Seattle Genetics, Inc. Treatment of sickle cell disease and inflammatory conditions
WO2016061583A1 (en) * 2014-10-17 2016-04-21 University Of Virginia Patent Foundation Compositions and methods for treating pituitary tumors
CN110615891B (zh) * 2019-08-16 2020-06-23 河南大学 一类茄呢基硫代水杨酸化合物、其制备方法及应用

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL107587A (en) * 1993-11-12 1998-08-16 Univ Ramot Farnesyl geranyl or geranyl-geranyl derivatives pharmaceutical compositions containing them and methods for their preparation
EP1187605A4 (de) * 1999-06-18 2004-05-26 Thyreos Corp BEHANDLUNG DER NICHT BöSARTIGEN KRANKHEITEN MIT RAS-ANTAGONISTEN
US6670330B1 (en) 2000-05-01 2003-12-30 Theodore J. Lampidis Cancer chemotherapy with 2-deoxy-D-glucose
CA2513399A1 (en) 2003-01-10 2004-07-29 Threshold Pharmaceuticals, Inc. Treatment of cancer with 2-deoxyglucose
US8088756B2 (en) * 2004-08-18 2012-01-03 Concordia Pharmaceuticals, Inc. Methods and compositions for oral delivery of FTS
ATE485037T1 (de) 2005-11-28 2010-11-15 Univ Ramot Krebsbehandlung mittels fts und 2-deoxyglucose
EP1986625B1 (de) 2006-02-10 2012-08-01 Ramot at Tel-Aviv University Ltd. Behandlung von ovarialkrebs
CA2648518C (en) 2006-04-11 2012-06-26 Ramot At Tel Aviv University Ltd. Treatment of hematological malignancies with fts and a bcr-abl tyrosine kinase inhibitor
EP2094260B1 (de) 2006-12-19 2012-02-01 Ramot at Tel-Aviv University Ltd. Behandlung von lungenkrebs

Also Published As

Publication number Publication date
WO2007064448A3 (en) 2007-08-23
EP1957060A2 (de) 2008-08-20
WO2007064448A2 (en) 2007-06-07
DE602006017728D1 (de) 2010-12-02
US8278349B2 (en) 2012-10-02
US20090286870A1 (en) 2009-11-19
EP1957060B1 (de) 2010-10-20

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