PL2282773T3 - Sposoby i kompozycje do wytwarzania przeciwciał i pochodnych przeciwciał o obniżonej fukozylacji rdzeniowej - Google Patents
Sposoby i kompozycje do wytwarzania przeciwciał i pochodnych przeciwciał o obniżonej fukozylacji rdzeniowejInfo
- Publication number
- PL2282773T3 PL2282773T3 PL09739983T PL09739983T PL2282773T3 PL 2282773 T3 PL2282773 T3 PL 2282773T3 PL 09739983 T PL09739983 T PL 09739983T PL 09739983 T PL09739983 T PL 09739983T PL 2282773 T3 PL2282773 T3 PL 2282773T3
- Authority
- PL
- Poland
- Prior art keywords
- compositions
- methods
- antibody derivatives
- making antibodies
- core fucosylation
- Prior art date
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/0018—Culture media for cell or tissue culture
- C12N5/0037—Serum-free medium, which may still contain naturally-sourced components
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H13/00—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids
- C07H13/02—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids
- C07H13/04—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids having the esterifying carboxyl radicals attached to acyclic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/72—Increased effector function due to an Fc-modification
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
- C07K2317/732—Antibody-dependent cellular cytotoxicity [ADCC]
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Biotechnology (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biophysics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Medicinal Chemistry (AREA)
- Immunology (AREA)
- General Engineering & Computer Science (AREA)
- Cell Biology (AREA)
- Microbiology (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
- Pyrane Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US5017308P | 2008-05-02 | 2008-05-02 | |
| US9270008P | 2008-08-28 | 2008-08-28 | |
| US10728908P | 2008-10-21 | 2008-10-21 | |
| PCT/US2009/042610 WO2009135181A2 (en) | 2008-05-02 | 2009-05-01 | Methods and compositions for making antibodies and antibody derivatives with reduced core fucosylation |
| EP09739983.6A EP2282773B2 (en) | 2008-05-02 | 2009-05-01 | Methods and compositions for making antibodies and antibody derivatives with reduced core fucosylation |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PL2282773T3 true PL2282773T3 (pl) | 2014-08-29 |
Family
ID=41255885
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL09739983T PL2282773T3 (pl) | 2008-05-02 | 2009-05-01 | Sposoby i kompozycje do wytwarzania przeciwciał i pochodnych przeciwciał o obniżonej fukozylacji rdzeniowej |
Country Status (9)
| Country | Link |
|---|---|
| US (7) | US8163551B2 (pl) |
| EP (1) | EP2282773B2 (pl) |
| JP (1) | JP5624535B2 (pl) |
| CN (1) | CN102076865B (pl) |
| AU (1) | AU2009242453B2 (pl) |
| CA (2) | CA2723197C (pl) |
| ES (1) | ES2458541T5 (pl) |
| PL (1) | PL2282773T3 (pl) |
| WO (1) | WO2009135181A2 (pl) |
Families Citing this family (180)
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| PL2282773T3 (pl) | 2008-05-02 | 2014-08-29 | Seattle Genetics Inc | Sposoby i kompozycje do wytwarzania przeciwciał i pochodnych przeciwciał o obniżonej fukozylacji rdzeniowej |
| CN104974251A (zh) | 2008-10-20 | 2015-10-14 | Abbvie公司 | 在抗体纯化过程中的病毒灭活 |
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| US11536713B2 (en) | 2009-12-25 | 2022-12-27 | Chugai Seiyaku Kabushiki Kaisha | Method for searching and screening for target of anti-cancer agent using non-human animal model having NOG established cancer cell line transplanted therein |
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| NZ604007A (en) | 2010-05-27 | 2015-03-27 | Genmab As | Monoclonal antibodies against her2 epitope |
| IL299365A (en) | 2010-05-27 | 2023-02-01 | Genmab As | Monoclonal antibodies against 2HER |
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| SG189302A1 (en) | 2010-10-06 | 2013-05-31 | Pharmalogicals Res Pte Ltd | Cancer stem cell population and method for production thereof |
| PT3156420T (pt) | 2010-12-06 | 2019-05-27 | Seattle Genetics Inc | Anticorpos humanizados a liv-1 e seu uso para tratar o cancro |
| WO2012143524A2 (en) | 2011-04-20 | 2012-10-26 | Genmab A/S | Bispecific antibodies against her2 and cd3 |
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| EP2699260B1 (en) | 2011-04-20 | 2024-11-20 | Genmab A/S | Bispecifc antibodies against her2 |
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| FR2976811A1 (fr) | 2011-06-22 | 2012-12-28 | Lfb Biotechnologies | Utilisation d'un anticorps anti-cd20 a haute adcc pour le traitement de la maladie de waldenstrom |
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| JP6077997B2 (ja) | 2011-09-07 | 2017-02-08 | 中外製薬株式会社 | 癌幹細胞の分離 |
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| IN2014CN03887A (pl) | 2011-10-27 | 2015-10-16 | Genmab As | |
| EP3603671A3 (en) * | 2011-10-28 | 2020-07-29 | Chugai Seiyaku Kabushiki Kaisha | Cancer stem cell-specific molecule |
| US10385395B2 (en) | 2012-04-11 | 2019-08-20 | The Regents Of The University Of California | Diagnostic tools for response to 6-thiopurine therapy |
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-
2009
- 2009-05-01 PL PL09739983T patent/PL2282773T3/pl unknown
- 2009-05-01 CN CN200980124932.4A patent/CN102076865B/zh active Active
- 2009-05-01 EP EP09739983.6A patent/EP2282773B2/en active Active
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- 2009-05-01 WO PCT/US2009/042610 patent/WO2009135181A2/en not_active Ceased
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Also Published As
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| JP5624535B2 (ja) | 2014-11-12 |
| US8993326B2 (en) | 2015-03-31 |
| ES2458541T5 (en) | 2025-08-04 |
| EP2282773A2 (en) | 2011-02-16 |
| CA2975228C (en) | 2020-07-21 |
| WO2009135181A2 (en) | 2009-11-05 |
| US20180155677A1 (en) | 2018-06-07 |
| US20150337259A1 (en) | 2015-11-26 |
| JP2011519567A (ja) | 2011-07-14 |
| CA2723197C (en) | 2017-09-19 |
| EP2282773B2 (en) | 2025-03-05 |
| EP2282773A4 (en) | 2012-11-14 |
| US11319526B2 (en) | 2022-05-03 |
| US20190276796A1 (en) | 2019-09-12 |
| US10443035B2 (en) | 2019-10-15 |
| AU2009242453A1 (en) | 2009-11-05 |
| US20230055475A1 (en) | 2023-02-23 |
| US8163551B2 (en) | 2012-04-24 |
| US9816069B2 (en) | 2017-11-14 |
| CA2975228A1 (en) | 2009-11-05 |
| CN102076865B (zh) | 2016-03-16 |
| US20120183997A1 (en) | 2012-07-19 |
| AU2009242453B2 (en) | 2014-12-04 |
| WO2009135181A3 (en) | 2010-02-25 |
| HK1154356A1 (en) | 2012-04-20 |
| US8574907B2 (en) | 2013-11-05 |
| US20090317869A1 (en) | 2009-12-24 |
| CA2723197A1 (en) | 2009-11-05 |
| EP2282773B1 (en) | 2014-01-15 |
| CN102076865A (zh) | 2011-05-25 |
| US20140031536A1 (en) | 2014-01-30 |
| ES2458541T3 (es) | 2014-05-06 |
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