ATE486078T1 - 5,6-disubstituierte oxadiazolopyrazine und thiadiazolopyrazine als liganden des cxc- chemokinrezeptors - Google Patents

5,6-disubstituierte oxadiazolopyrazine und thiadiazolopyrazine als liganden des cxc- chemokinrezeptors

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Publication number
ATE486078T1
ATE486078T1 AT06785619T AT06785619T ATE486078T1 AT E486078 T1 ATE486078 T1 AT E486078T1 AT 06785619 T AT06785619 T AT 06785619T AT 06785619 T AT06785619 T AT 06785619T AT E486078 T1 ATE486078 T1 AT E486078T1
Authority
AT
Austria
Prior art keywords
oxadiazolopyrazine
thiadiazolopyrazine
disubstituted
ligands
chemokine receptor
Prior art date
Application number
AT06785619T
Other languages
English (en)
Inventor
Biju Purakkattle
Original Assignee
Schering Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Corp filed Critical Schering Corp
Application granted granted Critical
Publication of ATE486078T1 publication Critical patent/ATE486078T1/de

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    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/04—Ortho-condensed systems
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    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6561—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing systems of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring or ring system, with or without other non-condensed hetero rings

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  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
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  • Ophthalmology & Optometry (AREA)
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AT06785619T 2005-06-29 2006-06-27 5,6-disubstituierte oxadiazolopyrazine und thiadiazolopyrazine als liganden des cxc- chemokinrezeptors ATE486078T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US69516205P 2005-06-29 2005-06-29
PCT/US2006/024908 WO2007005403A1 (en) 2005-06-29 2006-06-27 5,6-di-substituted oxadiazolopyrazines and thiadiazolopyrazines as cxc-chemokine receptor ligands

Publications (1)

Publication Number Publication Date
ATE486078T1 true ATE486078T1 (de) 2010-11-15

Family

ID=37137404

Family Applications (1)

Application Number Title Priority Date Filing Date
AT06785619T ATE486078T1 (de) 2005-06-29 2006-06-27 5,6-disubstituierte oxadiazolopyrazine und thiadiazolopyrazine als liganden des cxc- chemokinrezeptors

Country Status (10)

Country Link
US (1) US7897606B2 (de)
EP (1) EP1907399B1 (de)
JP (1) JP2009500328A (de)
CN (1) CN101253180B (de)
AT (1) ATE486078T1 (de)
CA (1) CA2613428A1 (de)
DE (1) DE602006017849D1 (de)
ES (1) ES2353401T3 (de)
MX (1) MX2008000367A (de)
WO (1) WO2007005403A1 (de)

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WO2005113534A2 (en) * 2004-05-12 2005-12-01 Schering Corporation Cxcr1 and cxcr2 chemokine antagonists
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WO2013192388A1 (en) 2012-06-20 2013-12-27 University Of Virginia Patent Foundation Compositions and methods for regulating glucose homeostasis and insulin action
US20250170127A1 (en) * 2022-02-21 2025-05-29 The Regents Of The University Of Colorado, A Body Corporate Re-sensitizing multidrug-resistant (mdr) gram-negative bacteria to colistin using ionophores
WO2023192935A1 (en) * 2022-03-30 2023-10-05 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Methods and compositions for the treatment for inflammation and fibrosis in retinal neovascular diseases

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CA2613428A1 (en) 2007-01-11
DE602006017849D1 (de) 2010-12-09
EP1907399A1 (de) 2008-04-09
CN101253180A (zh) 2008-08-27
EP1907399B1 (de) 2010-10-27
MX2008000367A (es) 2008-03-07
US20070015731A1 (en) 2007-01-18
US7897606B2 (en) 2011-03-01
JP2009500328A (ja) 2009-01-08
CN101253180B (zh) 2011-08-03
WO2007005403A1 (en) 2007-01-11

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