ATE486139T1 - Verfahren und vorrichtung zur nukleinsäuresequenzierung unter verwendung eines planaren wellenleiters - Google Patents
Verfahren und vorrichtung zur nukleinsäuresequenzierung unter verwendung eines planaren wellenleitersInfo
- Publication number
- ATE486139T1 ATE486139T1 AT06726800T AT06726800T ATE486139T1 AT E486139 T1 ATE486139 T1 AT E486139T1 AT 06726800 T AT06726800 T AT 06726800T AT 06726800 T AT06726800 T AT 06726800T AT E486139 T1 ATE486139 T1 AT E486139T1
- Authority
- AT
- Austria
- Prior art keywords
- nucleic acid
- planar waveguide
- acid sequencing
- sequencing
- methods
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 3
- 102000039446 nucleic acids Human genes 0.000 title abstract 3
- 108020004707 nucleic acids Proteins 0.000 title abstract 3
- 150000007523 nucleic acids Chemical class 0.000 title abstract 3
- 238000012163 sequencing technique Methods 0.000 title 1
- 238000006243 chemical reaction Methods 0.000 abstract 1
- 238000003384 imaging method Methods 0.000 abstract 1
- 239000002773 nucleotide Substances 0.000 abstract 1
- 125000003729 nucleotide group Chemical group 0.000 abstract 1
- 102000040430 polynucleotide Human genes 0.000 abstract 1
- 108091033319 polynucleotide Proteins 0.000 abstract 1
- 239000002157 polynucleotide Substances 0.000 abstract 1
- 238000003786 synthesis reaction Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6869—Methods for sequencing
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6869—Methods for sequencing
- C12Q1/6874—Methods for sequencing involving nucleic acid arrays, e.g. sequencing by hybridisation
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Analytical Chemistry (AREA)
- Physics & Mathematics (AREA)
- Immunology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB0507835.7A GB0507835D0 (en) | 2005-04-18 | 2005-04-18 | Method and device for nucleic acid sequencing using a planar wave guide |
| PCT/GB2006/001405 WO2006111729A1 (en) | 2005-04-18 | 2006-04-18 | Method and device for nucleic acid sequencing using a planar wave guide |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE486139T1 true ATE486139T1 (de) | 2010-11-15 |
Family
ID=34630886
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT06726800T ATE486139T1 (de) | 2005-04-18 | 2006-04-18 | Verfahren und vorrichtung zur nukleinsäuresequenzierung unter verwendung eines planaren wellenleiters |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US20090247414A1 (de) |
| EP (1) | EP1871902B1 (de) |
| AT (1) | ATE486139T1 (de) |
| DE (1) | DE602006017817D1 (de) |
| GB (1) | GB0507835D0 (de) |
| WO (1) | WO2006111729A1 (de) |
Families Citing this family (71)
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| US8207509B2 (en) | 2006-09-01 | 2012-06-26 | Pacific Biosciences Of California, Inc. | Substrates, systems and methods for analyzing materials |
| AU2007289057C1 (en) | 2006-09-01 | 2014-01-16 | Pacific Biosciences Of California, Inc. | Substrates, systems and methods for analyzing materials |
| US8471230B2 (en) | 2006-09-01 | 2013-06-25 | Pacific Biosciences Of California, Inc. | Waveguide substrates and optical systems and methods of use thereof |
| US8994946B2 (en) | 2010-02-19 | 2015-03-31 | Pacific Biosciences Of California, Inc. | Integrated analytical system and method |
| EP2933629B1 (de) | 2010-02-19 | 2019-04-10 | Pacific Biosciences Of California, Inc. | System zur Messung von analytischen Reaktionen umfassend eine Buchse für einen Optode-Arraychip |
| WO2012175245A2 (en) | 2011-06-21 | 2012-12-27 | Illumina Cambridge Limited | Methods and systems for data analysis |
| US9453258B2 (en) | 2011-09-23 | 2016-09-27 | Illumina, Inc. | Methods and compositions for nucleic acid sequencing |
| ES2929040T3 (es) * | 2011-10-28 | 2022-11-24 | Aeneas Gmbh & Co Kg | Dispositivo y procedimiento para detectar sustancias presentes en muestras biológicas o químicas |
| US20130261984A1 (en) | 2012-03-30 | 2013-10-03 | Illumina, Inc. | Methods and systems for determining fetal chromosomal abnormalities |
| US9372308B1 (en) | 2012-06-17 | 2016-06-21 | Pacific Biosciences Of California, Inc. | Arrays of integrated analytical devices and methods for production |
| US9977861B2 (en) | 2012-07-18 | 2018-05-22 | Illumina Cambridge Limited | Methods and systems for determining haplotypes and phasing of haplotypes |
| EP2885626B1 (de) | 2012-08-20 | 2020-03-04 | Illumina, Inc. | Ein integriertes detektions-, durchflusszell- und photonik-gerät (dfp) |
| EP2936222B1 (de) | 2012-12-18 | 2019-07-03 | Pacific Biosciences Of California, Inc. | Eine optische analysevorrichtung |
| WO2014130900A1 (en) | 2013-02-22 | 2014-08-28 | Pacific Biosciences Of California, Inc. | Integrated illumination of optical analytical devices |
| US9896686B2 (en) | 2014-01-09 | 2018-02-20 | AgBiome, Inc. | High throughput discovery of new genes from complex mixtures of environmental microbes |
| CN107003241B (zh) | 2014-08-27 | 2022-01-11 | 加利福尼亚太平洋生物科学股份有限公司 | 集成分析器件阵列 |
| US10302972B2 (en) | 2015-01-23 | 2019-05-28 | Pacific Biosciences Of California, Inc. | Waveguide transmission |
| CN113064236B (zh) | 2015-03-16 | 2022-11-01 | 加利福尼亚太平洋生物科学股份有限公司 | 用于自由空间光耦合的集成装置及系统 |
| CA2983882C (en) | 2015-05-07 | 2023-10-03 | Scott E. Helgesen | Multiprocessor pipeline architecture |
| AU2016276980B2 (en) | 2015-06-12 | 2021-09-23 | Pacific Biosciences Of California, Inc. | Integrated target waveguide devices and systems for optical coupling |
| WO2017218908A2 (en) | 2016-06-16 | 2017-12-21 | The Johns Hopkins University | Methods and system for epigenetic analysis |
| WO2018187013A1 (en) | 2017-04-04 | 2018-10-11 | Omniome, Inc. | Fluidic apparatus and methods useful for chemical and biological reactions |
| JP2021500531A (ja) | 2017-08-15 | 2021-01-07 | オムニオム インコーポレイテッドOmniome, Inc. | 化学的および生物学的検体の検出に有用なスキャン装置および方法 |
| WO2019036055A2 (en) | 2017-08-18 | 2019-02-21 | Ignite Biosciences, Inc. | METHODS OF SELECTING BINDING REAGENTS |
| WO2019126040A1 (en) | 2017-12-21 | 2019-06-27 | Illumina, Inc. | Flow cells with hydrogel coating |
| KR102511896B1 (ko) * | 2018-03-29 | 2023-03-20 | 일루미나, 인코포레이티드 | 대물 렌즈를 사용하는 형광 이미징을 위한 조명 |
| US20210172008A1 (en) | 2018-04-04 | 2021-06-10 | Lifeedit, Inc. | Methods and compositions to identify novel crispr systems |
| CA3097583A1 (en) | 2018-04-19 | 2019-10-24 | Omniome, Inc. | Improving accuracy of base calls in nucleic acid sequencing methods |
| JP2022513092A (ja) | 2018-11-20 | 2022-02-07 | ノーティラス・バイオテクノロジー・インコーポレイテッド | 親和性試薬の設計および選択 |
| CN211311438U (zh) | 2018-12-04 | 2020-08-21 | 欧姆尼欧美公司 | 流动池 |
| EP3899032A2 (de) | 2018-12-20 | 2021-10-27 | Omniome, Inc. | Temperaturkontrolle zur analyse von nukleinsäuren und anderen analyten |
| US11499189B2 (en) | 2019-02-14 | 2022-11-15 | Pacific Biosciences Of California, Inc. | Mitigating adverse impacts of detection systems on nucleic acids and other biological analytes |
| US11680950B2 (en) | 2019-02-20 | 2023-06-20 | Pacific Biosciences Of California, Inc. | Scanning apparatus and methods for detecting chemical and biological analytes |
| AU2020266136B2 (en) | 2019-04-29 | 2026-04-02 | Nautilus Subsidiary, Inc. | Methods and systems for integrated on-chip single-molecule detection |
| NL2023516B1 (en) * | 2019-05-28 | 2020-12-08 | Illumina Inc | Manufacturing a flowcell with a planar waveguide |
| WO2020240453A1 (en) * | 2019-05-28 | 2020-12-03 | Illumina, Inc. | Manufacturing a flowcell with a planar waveguide |
| US11644406B2 (en) | 2019-06-11 | 2023-05-09 | Pacific Biosciences Of California, Inc. | Calibrated focus sensing |
| MY209672A (en) | 2019-06-28 | 2025-07-30 | Illumina Inc | Flowcells with linear waveguides |
| US10656368B1 (en) | 2019-07-24 | 2020-05-19 | Omniome, Inc. | Method and system for biological imaging using a wide field objective lens |
| EP4028407B1 (de) | 2019-09-10 | 2023-08-16 | Pacific Biosciences of California, Inc. | Reversible nukleotide änderung |
| US20210139867A1 (en) | 2019-11-08 | 2021-05-13 | Omniome, Inc. | Engineered polymerases for improved sequencing by binding |
| DE202019106694U1 (de) | 2019-12-02 | 2020-03-19 | Omniome, Inc. | System zur Sequenzierung von Nukleinsäuren in Fluidschaum |
| WO2021158511A1 (en) | 2020-02-04 | 2021-08-12 | Omniome, Inc. | Flow cells and methods for their manufacture and use |
| US12535420B2 (en) | 2020-02-18 | 2026-01-27 | Pacific Biosciences Of California, Inc. | Highly multiplexed nucleic acid sequencing systems |
| CA3182266A1 (en) | 2020-06-11 | 2021-12-16 | Vadim Lobanov | Methods and systems for computational decoding of biological, chemical, and physical entities |
| CA3196800A1 (en) | 2020-10-30 | 2022-05-05 | Element Biosciences, Inc. | Reagents for massively parallel nucleic acid sequencing |
| EP4244382A1 (de) | 2020-11-11 | 2023-09-20 | Nautilus Subsidiary, Inc. | Affinitätsreagenzien mit verbesserten bindungs- und nachweiseigenschaften |
| US20220227890A1 (en) | 2021-01-21 | 2022-07-21 | Nautilus Biotechnology, Inc. | Systems and methods for biomolecule preparation |
| IL305336B2 (en) | 2021-03-11 | 2025-09-01 | Nautilus Subsidiary Inc | Systems and methods for preserving biomolecules |
| WO2022235794A1 (en) | 2021-05-04 | 2022-11-10 | Pacific Biosciences Of California, Inc. | Arrays of integrated analytical devices with reduced-scale unit cell |
| US11859241B2 (en) | 2021-06-17 | 2024-01-02 | Element Biosciences, Inc. | Compositions and methods for pairwise sequencing |
| US11220707B1 (en) | 2021-06-17 | 2022-01-11 | Element Biosciences, Inc. | Compositions and methods for pairwise sequencing |
| US12139727B2 (en) | 2021-06-18 | 2024-11-12 | Element Biosciences, Inc. | Engineered polymerases |
| EP4399528A1 (de) | 2021-09-09 | 2024-07-17 | Nautilus Subsidiary, Inc. | Charakterisierung und lokalisierung von proteinmodifikationen |
| EP4405683A1 (de) | 2021-09-22 | 2024-07-31 | Nautilus Subsidiary, Inc. | Verfahren und systeme zur bestimmung von polypeptidinteraktionen |
| WO2023081728A1 (en) | 2021-11-03 | 2023-05-11 | Nautilus Biotechnology, Inc. | Systems and methods for surface structuring |
| US12006518B2 (en) | 2022-02-18 | 2024-06-11 | Element Biosciences, Inc. | Engineered polymerases with reduced sequence-specific errors |
| CA3245990A1 (en) | 2022-03-29 | 2023-10-05 | Nautilus Subsidiary, Inc. | INTEGRATED NETWORKS FOR SINGLE-ANALYTE PROCESSES |
| WO2023250364A1 (en) | 2022-06-21 | 2023-12-28 | Nautilus Subsidiary, Inc. | Method for detecting analytes at sites of optically non-resolvable distances |
| WO2024015962A1 (en) | 2022-07-15 | 2024-01-18 | Pacific Biosciences Of California, Inc. | Blocked asymmetric hairpin adaptors |
| CA3264896A1 (en) | 2022-08-15 | 2024-02-22 | Element Biosciences, Inc. | SPATIAL RESOLUTION SURFACE CAPTURE OF NUCLEIC ACIDS |
| WO2024073599A1 (en) | 2022-09-29 | 2024-04-04 | Nautilus Subsidiary, Inc. | Preparation of array surfaces for single-analyte processes |
| US20240192202A1 (en) | 2022-12-09 | 2024-06-13 | Nautilus Subsidiary, Inc. | Fluidic media for single-analtye arrays |
| EP4634285A1 (de) | 2022-12-15 | 2025-10-22 | Nautilus Subsidiary, Inc. | Hemmung von photonenphänomenen auf einzelmolekülarrays |
| US20240394902A1 (en) | 2023-05-24 | 2024-11-28 | Nautilus Subsidiary, Inc. | Systems and methods for machine vision |
| EP4739790A1 (de) | 2023-07-06 | 2026-05-13 | Pacific Biosciences of California, Inc. | Verfahren und zusammensetzungen zur stabilisierung von konkateren |
| US20250066841A1 (en) | 2023-08-24 | 2025-02-27 | Nautilus Subsidiary, Inc. | Compositions and methods for detecting binding interactions under equilibrium or non-equilibrium conditions |
| US20250189519A1 (en) | 2023-12-11 | 2025-06-12 | Nautilus Subsidiary, Inc. | Methods and compositions of particle-based arrays |
| US20250205706A1 (en) | 2023-12-20 | 2025-06-26 | Nautilus Subsidiary, Inc. | Fluidic devices for single-analyte assays |
| US20250298016A1 (en) | 2024-03-22 | 2025-09-25 | Nautilus Subsidiary, Inc. | Plasmonic particle systems for single-analyte assays |
| US20250305034A1 (en) | 2024-04-01 | 2025-10-02 | Nautilus Subsidiary, Inc. | Nanostructures for modulation of analyte conformation |
Family Cites Families (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4582809A (en) * | 1982-06-14 | 1986-04-15 | Myron J. Block | Apparatus including optical fiber for fluorescence immunoassay |
| EP0341928A1 (de) * | 1988-05-10 | 1989-11-15 | AMERSHAM INTERNATIONAL plc | Oberflächen-Resonanzplasmawellen-Sensoren |
| US5547839A (en) * | 1989-06-07 | 1996-08-20 | Affymax Technologies N.V. | Sequencing of surface immobilized polymers utilizing microflourescence detection |
| US5302509A (en) * | 1989-08-14 | 1994-04-12 | Beckman Instruments, Inc. | Method for sequencing polynucleotides |
| US5512492A (en) * | 1993-05-18 | 1996-04-30 | University Of Utah Research Foundation | Waveguide immunosensor with coating chemistry providing enhanced sensitivity |
| US5516703A (en) * | 1993-08-20 | 1996-05-14 | The University Of Utah | Coating of hydrophobic surfaces to render them protein resistant while permitting covalent attachment of specific ligands |
| MXPA96005828A (es) * | 1994-05-27 | 2005-07-15 | Novartis Ag Tambien Denominada | Proceso para detectar luminescencia excitada evanescentemente. |
| US5763594A (en) * | 1994-09-02 | 1998-06-09 | Andrew C. Hiatt | 3' protected nucleotides for enzyme catalyzed template-independent creation of phosphodiester bonds |
| US5796909A (en) * | 1996-02-14 | 1998-08-18 | Islam; Mohammed N. | All-fiber, high-sensitivity, near-field optical microscopy instrument employing guided wave light collector and specimen support |
| GB9805935D0 (en) * | 1998-03-19 | 1998-05-13 | Ciba Geigy Ag | Organic compounds |
| US6787308B2 (en) * | 1998-07-30 | 2004-09-07 | Solexa Ltd. | Arrayed biomolecules and their use in sequencing |
| WO2000050871A1 (en) * | 1999-02-26 | 2000-08-31 | Orchid Biosciences, Inc. | Microstructures for use in biological assays and reactions |
| JP2003531372A (ja) * | 2000-04-14 | 2003-10-21 | ツェプトゼンス アクチエンゲゼルシャフト | 励起フィールドを強化するための格子導波路構造及びその使用 |
| EP3034627B1 (de) * | 2000-10-06 | 2019-01-30 | The Trustees of Columbia University in the City of New York | Massives paralleles verfahren zum entschlüsseln von dna und rna |
| UA75375C2 (en) * | 2000-10-12 | 2006-04-17 | Boehringer Ingelheim Pharma | Method for producing powdery preparations for inhaling |
| US7057026B2 (en) * | 2001-12-04 | 2006-06-06 | Solexa Limited | Labelled nucleotides |
| JP2005519593A (ja) * | 2002-01-18 | 2005-07-07 | ユニバーシティ オブ ユタ リサーチ ファウンデーション | 平面導波路を使用する1塩基多型の検出法 |
| AU2003259350A1 (en) * | 2002-08-23 | 2004-03-11 | Solexa Limited | Modified nucleotides for polynucleotide sequencing |
| US7414116B2 (en) * | 2002-08-23 | 2008-08-19 | Illumina Cambridge Limited | Labelled nucleotides |
| US20050170367A1 (en) * | 2003-06-10 | 2005-08-04 | Quake Stephen R. | Fluorescently labeled nucleoside triphosphates and analogs thereof for sequencing nucleic acids |
| US20050153320A1 (en) * | 2003-11-06 | 2005-07-14 | Herron James N. | Single base extension |
| US7233391B2 (en) * | 2003-11-21 | 2007-06-19 | Perkinelmer Las, Inc. | Optical device integrated with well |
| GB0517097D0 (en) * | 2005-08-19 | 2005-09-28 | Solexa Ltd | Modified nucleosides and nucleotides and uses thereof |
-
2005
- 2005-04-18 GB GBGB0507835.7A patent/GB0507835D0/en not_active Ceased
-
2006
- 2006-04-18 AT AT06726800T patent/ATE486139T1/de not_active IP Right Cessation
- 2006-04-18 EP EP06726800A patent/EP1871902B1/de not_active Expired - Lifetime
- 2006-04-18 WO PCT/GB2006/001405 patent/WO2006111729A1/en not_active Ceased
- 2006-04-18 DE DE602006017817T patent/DE602006017817D1/de not_active Expired - Lifetime
- 2006-04-18 US US11/918,609 patent/US20090247414A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| GB0507835D0 (en) | 2005-05-25 |
| WO2006111729A1 (en) | 2006-10-26 |
| EP1871902B1 (de) | 2010-10-27 |
| US20090247414A1 (en) | 2009-10-01 |
| DE602006017817D1 (de) | 2010-12-09 |
| EP1871902A1 (de) | 2008-01-02 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |