ATE486139T1 - Verfahren und vorrichtung zur nukleinsäuresequenzierung unter verwendung eines planaren wellenleiters - Google Patents

Verfahren und vorrichtung zur nukleinsäuresequenzierung unter verwendung eines planaren wellenleiters

Info

Publication number
ATE486139T1
ATE486139T1 AT06726800T AT06726800T ATE486139T1 AT E486139 T1 ATE486139 T1 AT E486139T1 AT 06726800 T AT06726800 T AT 06726800T AT 06726800 T AT06726800 T AT 06726800T AT E486139 T1 ATE486139 T1 AT E486139T1
Authority
AT
Austria
Prior art keywords
nucleic acid
planar waveguide
acid sequencing
sequencing
methods
Prior art date
Application number
AT06726800T
Other languages
English (en)
Inventor
Bojan Obradovic
John West
Harold Swerdlow
Original Assignee
Illumina Cambridge Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=34630886&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATE486139(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Illumina Cambridge Ltd filed Critical Illumina Cambridge Ltd
Application granted granted Critical
Publication of ATE486139T1 publication Critical patent/ATE486139T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6869Methods for sequencing
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6869Methods for sequencing
    • C12Q1/6874Methods for sequencing involving nucleic acid arrays, e.g. sequencing by hybridisation

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
AT06726800T 2005-04-18 2006-04-18 Verfahren und vorrichtung zur nukleinsäuresequenzierung unter verwendung eines planaren wellenleiters ATE486139T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB0507835.7A GB0507835D0 (en) 2005-04-18 2005-04-18 Method and device for nucleic acid sequencing using a planar wave guide
PCT/GB2006/001405 WO2006111729A1 (en) 2005-04-18 2006-04-18 Method and device for nucleic acid sequencing using a planar wave guide

Publications (1)

Publication Number Publication Date
ATE486139T1 true ATE486139T1 (de) 2010-11-15

Family

ID=34630886

Family Applications (1)

Application Number Title Priority Date Filing Date
AT06726800T ATE486139T1 (de) 2005-04-18 2006-04-18 Verfahren und vorrichtung zur nukleinsäuresequenzierung unter verwendung eines planaren wellenleiters

Country Status (6)

Country Link
US (1) US20090247414A1 (de)
EP (1) EP1871902B1 (de)
AT (1) ATE486139T1 (de)
DE (1) DE602006017817D1 (de)
GB (1) GB0507835D0 (de)
WO (1) WO2006111729A1 (de)

Families Citing this family (71)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2008028160A2 (en) 2006-09-01 2008-03-06 Pacific Biosciences Of California, Inc. Substrates, systems and methods for analyzing materials
US8207509B2 (en) 2006-09-01 2012-06-26 Pacific Biosciences Of California, Inc. Substrates, systems and methods for analyzing materials
EP2331934B1 (de) 2008-09-16 2020-01-01 Pacific Biosciences of California, Inc. Analysegerät mit Nullmoden-Wellenleiter Substrat
US8994946B2 (en) 2010-02-19 2015-03-31 Pacific Biosciences Of California, Inc. Integrated analytical system and method
EP3460458B1 (de) 2010-02-19 2021-08-11 Pacific Biosciences of California, Inc. Verfahren zur nukleinsäuresequenzierung
AU2012272161B2 (en) 2011-06-21 2015-12-24 Illumina Cambridge Limited Methods and systems for data analysis
CA2859660C (en) 2011-09-23 2021-02-09 Illumina, Inc. Methods and compositions for nucleic acid sequencing
WO2013060482A1 (de) * 2011-10-28 2013-05-02 Torsten Matthias Vorrichtung und verfahren zum nachweis von in biologischen oder chemischen proben vorliegenden substanzen
US20130261984A1 (en) 2012-03-30 2013-10-03 Illumina, Inc. Methods and systems for determining fetal chromosomal abnormalities
US9372308B1 (en) 2012-06-17 2016-06-21 Pacific Biosciences Of California, Inc. Arrays of integrated analytical devices and methods for production
US9977861B2 (en) * 2012-07-18 2018-05-22 Illumina Cambridge Limited Methods and systems for determining haplotypes and phasing of haplotypes
WO2014031157A1 (en) 2012-08-20 2014-02-27 Illumina, Inc. Method and system for fluorescence lifetime based sequencing
EP2936222B1 (de) 2012-12-18 2019-07-03 Pacific Biosciences Of California, Inc. Eine optische analysevorrichtung
US9624540B2 (en) 2013-02-22 2017-04-18 Pacific Biosciences Of California, Inc. Integrated illumination of optical analytical devices
US9896686B2 (en) 2014-01-09 2018-02-20 AgBiome, Inc. High throughput discovery of new genes from complex mixtures of environmental microbes
TWI692633B (zh) 2014-08-27 2020-05-01 美商加州太平洋生物科學公司 整合式分析裝置之陣列
US10302972B2 (en) 2015-01-23 2019-05-28 Pacific Biosciences Of California, Inc. Waveguide transmission
EP3271762B1 (de) 2015-03-16 2023-01-04 Pacific Biosciences of California, Inc. Analysesystem umfassend integrierte vorrichtungen und systeme zur optischen freiraumkopplung
EP3292220B1 (de) 2015-05-07 2022-07-13 Pacific Biosciences of California, Inc. Multiprozessor-pipeline-architektur
EP4425153A3 (de) 2015-06-12 2024-11-20 Pacific Biosciences Of California, Inc. Integrierte zielwellenleitervorrichtungen und systeme zur optischen kopplung
EP3472358B1 (de) 2016-06-16 2021-08-18 The Johns Hopkins University Verfahren und system für epigenetische analyse
WO2018187013A1 (en) 2017-04-04 2018-10-11 Omniome, Inc. Fluidic apparatus and methods useful for chemical and biological reactions
WO2019035897A1 (en) 2017-08-15 2019-02-21 Omniome, Inc. SCANNING APPARATUS AND METHODS USEFUL FOR DETECTION OF CHEMICAL OR BIOLOGICAL ANALYTES
CN111566261B (zh) 2017-08-18 2025-03-25 诺迪勒思附属公司 选择结合试剂的方法
EP3727674A4 (de) * 2017-12-21 2021-10-13 Illumina Inc. Flusszellen mit hydrogelbeschichtung
NZ760171A (en) 2018-03-29 2023-05-26 Illumina Inc Illumination for fluorescence imaging using objective lens
US20210172008A1 (en) 2018-04-04 2021-06-10 Lifeedit, Inc. Methods and compositions to identify novel crispr systems
WO2019203986A1 (en) 2018-04-19 2019-10-24 Omniome, Inc. Improving accuracy of base calls in nucleic acid sequencing methods
US11993865B2 (en) 2018-11-20 2024-05-28 Nautilus Subsidiary, Inc. Selection of affinity reagents
EP3891304A1 (de) 2018-12-04 2021-10-13 Omniome, Inc. Mischphasenfluide für nukleinsäuresequenzierung und andere analytische tests
EP3899032A2 (de) 2018-12-20 2021-10-27 Omniome, Inc. Temperaturkontrolle zur analyse von nukleinsäuren und anderen analyten
WO2020167574A1 (en) 2019-02-14 2020-08-20 Omniome, Inc. Mitigating adverse impacts of detection systems on nucleic acids and other biological analytes
US11680950B2 (en) 2019-02-20 2023-06-20 Pacific Biosciences Of California, Inc. Scanning apparatus and methods for detecting chemical and biological analytes
CA3135206A1 (en) 2019-04-29 2020-11-05 Pierre Indermuhle Methods and systems for integrated on-chip single-molecule detection
WO2020240453A1 (en) * 2019-05-28 2020-12-03 Illumina, Inc. Manufacturing a flowcell with a planar waveguide
NL2023516B1 (en) * 2019-05-28 2020-12-08 Illumina Inc Manufacturing a flowcell with a planar waveguide
US11644406B2 (en) 2019-06-11 2023-05-09 Pacific Biosciences Of California, Inc. Calibrated focus sensing
SG11202012996UA (en) 2019-06-28 2021-02-25 Illumina Cambridge Ltd Flowcells with linear waveguides
US10656368B1 (en) 2019-07-24 2020-05-19 Omniome, Inc. Method and system for biological imaging using a wide field objective lens
CN114728996B (zh) 2019-09-10 2022-11-29 加利福尼亚太平洋生物科学股份有限公司 核苷酸的可逆修饰
EP4055155A1 (de) 2019-11-08 2022-09-14 Pacific Biosciences of California, Inc. Modifizierte polymerasen zur verbesserten sequenzierung durch bindung
DE202019106694U1 (de) 2019-12-02 2020-03-19 Omniome, Inc. System zur Sequenzierung von Nukleinsäuren in Fluidschaum
EP4100161B1 (de) 2020-02-04 2024-07-10 Pacific Biosciences of California, Inc. Durchflusszellen und verfahren zu deren verwendung
US12535420B2 (en) 2020-02-18 2026-01-27 Pacific Biosciences Of California, Inc. Highly multiplexed nucleic acid sequencing systems
WO2021252800A1 (en) 2020-06-11 2021-12-16 Nautilus Biotechnology, Inc. Methods and systems for computational decoding of biological, chemical, and physical entities
CA3196800A1 (en) * 2020-10-30 2022-05-05 Element Biosciences, Inc. Reagents for massively parallel nucleic acid sequencing
AU2021378290B2 (en) 2020-11-11 2025-10-30 Nautilus Subsidiary, Inc. Affinity reagents having enhanced binding and detection characteristics
WO2022159663A1 (en) 2021-01-21 2022-07-28 Nautilus Biotechnology, Inc. Systems and methods for biomolecule preparation
IL305336B2 (en) 2021-03-11 2025-09-01 Nautilus Subsidiary Inc Systems and methods for preserving biomolecules
KR20240006033A (ko) 2021-05-04 2024-01-12 퍼시픽 바이오사이언스 오브 캘리포니아, 인크. 축소된 규모의 단위 셀을 갖는 통합 분석 장치의 어레이
US11427855B1 (en) 2021-06-17 2022-08-30 Element Biosciences, Inc. Compositions and methods for pairwise sequencing
US11859241B2 (en) 2021-06-17 2024-01-02 Element Biosciences, Inc. Compositions and methods for pairwise sequencing
US20220403351A1 (en) 2021-06-18 2022-12-22 Element Biosciences, Inc. Engineered polymerases
CA3227872A1 (en) 2021-09-09 2023-03-16 James Henry JOLY Characterization and localization of protein modifications
AU2022352593B2 (en) 2021-09-22 2026-03-26 Nautilus Subsidiary, Inc. Methods and systems for determining polypeptide interactions
WO2023081728A1 (en) 2021-11-03 2023-05-11 Nautilus Biotechnology, Inc. Systems and methods for surface structuring
US11788075B2 (en) 2022-02-18 2023-10-17 Element Biosciences, Inc. Engineered polymerases with reduced sequence-specific errors
US12092578B2 (en) 2022-03-29 2024-09-17 Nautilus Subsidiary, Inc. Integrated arrays for single-analyte processes
US20250376716A1 (en) 2022-06-21 2025-12-11 Nautilus Subsidiary, Inc. Method for detecting analytes at sites of optically non-resolvable distances
WO2024015962A1 (en) 2022-07-15 2024-01-18 Pacific Biosciences Of California, Inc. Blocked asymmetric hairpin adaptors
EP4573213A1 (de) 2022-08-15 2025-06-25 Element Biosciences, Inc. Ortsaufgelöste oberflächenerfassung von nukleinsäuren
WO2024073599A1 (en) 2022-09-29 2024-04-04 Nautilus Subsidiary, Inc. Preparation of array surfaces for single-analyte processes
US20240192202A1 (en) 2022-12-09 2024-06-13 Nautilus Subsidiary, Inc. Fluidic media for single-analtye arrays
US20240201182A1 (en) 2022-12-15 2024-06-20 Nautilus Subsidiary, Inc. Inhibition of photon phenomena on single molecule arrays
WO2024243237A1 (en) 2023-05-24 2024-11-28 Nautilus Subsidiary, Inc. Systems and methods for machine vision
WO2025010160A1 (en) 2023-07-06 2025-01-09 Pacific Biosciences Of California, Inc. Methods and compositions for stabilizing concatemers
US20250066841A1 (en) 2023-08-24 2025-02-27 Nautilus Subsidiary, Inc. Compositions and methods for detecting binding interactions under equilibrium or non-equilibrium conditions
US20250189519A1 (en) 2023-12-11 2025-06-12 Nautilus Subsidiary, Inc. Methods and compositions of particle-based arrays
US20250205706A1 (en) 2023-12-20 2025-06-26 Nautilus Subsidiary, Inc. Fluidic devices for single-analyte assays
US20250298016A1 (en) 2024-03-22 2025-09-25 Nautilus Subsidiary, Inc. Plasmonic particle systems for single-analyte assays
US20250305034A1 (en) 2024-04-01 2025-10-02 Nautilus Subsidiary, Inc. Nanostructures for modulation of analyte conformation

Family Cites Families (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4582809A (en) * 1982-06-14 1986-04-15 Myron J. Block Apparatus including optical fiber for fluorescence immunoassay
EP0341928A1 (de) * 1988-05-10 1989-11-15 AMERSHAM INTERNATIONAL plc Oberflächen-Resonanzplasmawellen-Sensoren
US5547839A (en) * 1989-06-07 1996-08-20 Affymax Technologies N.V. Sequencing of surface immobilized polymers utilizing microflourescence detection
US5302509A (en) * 1989-08-14 1994-04-12 Beckman Instruments, Inc. Method for sequencing polynucleotides
US5516703A (en) * 1993-08-20 1996-05-14 The University Of Utah Coating of hydrophobic surfaces to render them protein resistant while permitting covalent attachment of specific ligands
US5512492A (en) * 1993-05-18 1996-04-30 University Of Utah Research Foundation Waveguide immunosensor with coating chemistry providing enhanced sensitivity
MXPA96005828A (es) * 1994-05-27 2005-07-15 Novartis Ag Tambien Denominada Proceso para detectar luminescencia excitada evanescentemente.
US5763594A (en) * 1994-09-02 1998-06-09 Andrew C. Hiatt 3' protected nucleotides for enzyme catalyzed template-independent creation of phosphodiester bonds
US5796909A (en) * 1996-02-14 1998-08-18 Islam; Mohammed N. All-fiber, high-sensitivity, near-field optical microscopy instrument employing guided wave light collector and specimen support
GB9805935D0 (en) * 1998-03-19 1998-05-13 Ciba Geigy Ag Organic compounds
US6787308B2 (en) * 1998-07-30 2004-09-07 Solexa Ltd. Arrayed biomolecules and their use in sequencing
AU3508600A (en) * 1999-02-26 2000-09-14 Orchid Biosciences, Inc. Microstructures for use in biological assays and reactions
AU2001262178A1 (en) * 2000-04-14 2001-10-30 Zeptosens Ag Grid-waveguide structure for reinforcing an excitation field and use thereof
AU2001296645A1 (en) * 2000-10-06 2002-04-15 The Trustees Of Columbia University In The City Of New York Massive parallel method for decoding dna and rna
UA75375C2 (en) * 2000-10-12 2006-04-17 Boehringer Ingelheim Pharma Method for producing powdery preparations for inhaling
US7057026B2 (en) * 2001-12-04 2006-06-06 Solexa Limited Labelled nucleotides
WO2003062791A2 (en) * 2002-01-18 2003-07-31 University Of Utah Research Foundation Detection of single nucleotide polymorphisms using planar waveguides
WO2004018497A2 (en) * 2002-08-23 2004-03-04 Solexa Limited Modified nucleotides for polynucleotide sequencing
US7414116B2 (en) * 2002-08-23 2008-08-19 Illumina Cambridge Limited Labelled nucleotides
US20050170367A1 (en) * 2003-06-10 2005-08-04 Quake Stephen R. Fluorescently labeled nucleoside triphosphates and analogs thereof for sequencing nucleic acids
US20050153320A1 (en) * 2003-11-06 2005-07-14 Herron James N. Single base extension
WO2005052644A2 (en) * 2003-11-21 2005-06-09 Perkinelmer Las, Inc. Optical device integrated with well
GB0517097D0 (en) * 2005-08-19 2005-09-28 Solexa Ltd Modified nucleosides and nucleotides and uses thereof

Also Published As

Publication number Publication date
DE602006017817D1 (de) 2010-12-09
US20090247414A1 (en) 2009-10-01
WO2006111729A1 (en) 2006-10-26
EP1871902A1 (de) 2008-01-02
GB0507835D0 (en) 2005-05-25
EP1871902B1 (de) 2010-10-27

Similar Documents

Publication Publication Date Title
ATE486139T1 (de) Verfahren und vorrichtung zur nukleinsäuresequenzierung unter verwendung eines planaren wellenleiters
ATE522627T1 (de) Verfahren zur herstellung von nukleinsäuresonden
DE602007007924D1 (de) Verfahren zur erhöhung der genauigkeit einer nukleinsäuresequenzierung
ATE496141T1 (de) Verfahren und system zum analysieren von reaktionen unter verwendung eines informationssystems
DE60234540D1 (de) Verfahren zum nachweis von nukleinsäure mittels dna-mikroarrays und vorrichtung zum nukleinsäurenachweis
DE60041355D1 (de) Verfahren zur detektion von erkrankungen
EP2292727A4 (de) Einzelmolekül-echtzeit-sequenziergerät, nukleinsäure-analysegerät und einzelmolekül-echtzeit-sequenzierverfahren
ATE521948T1 (de) System und verfahren zur nukleinsäuresequenzierung
ATE468915T1 (de) Vorrichtung und verfahren zur sequenzierung einer nukleinsäure
DE60127469D1 (de) Potentiometrischer dna-mikroarray, verfahren zu dessen herstellung und verfahren zur nukleinsäureanalyse
EA202192446A1 (ru) Диагностика фетальной хромосомной анэуплоидии с использованием геномного секвенирования
DE60042695D1 (de) Verfahren für den nachweis von erkrankungen
ATE463584T1 (de) Verfahren zur analyse von polynukleotidsequenzen
EP1766075A4 (de) Verfahren zur nukleinsäureanalyse
DE602006012052D1 (de) Verfahren zur sequenzierung einer polynukleotidmatrize
DE60326748D1 (de) Verfahren zur identifizierung des brustkrebsrisikos
MY199897A (en) Accurate quantification of fetal dna fraction by shallow-depth sequencing of maternal plasma dna
EP2077513A4 (de) Verfahren zum identifizieren einer nukleotidsequenz und verfahren zum erhalten der sekundärstruktur eines nukleinsäuremoleküls, vorrichtung zum identifizieren einer nukleotidsequenz und vorrichtung zum erhalten der sekundärstruktur eines nukleinsäuremoleküls und programm zum identifizieren einer nukleotidsequenz und programm zum erhalten der sekundärstruktur
DE602005009693D1 (de) 2"-nitrobenzyl-modifizierte ribonukleotide
ATE445715T1 (de) Elektrokatalytischer nukleinsäurehybridisierungsnachweis
DE602007010375D1 (de) Verfahren und Vorrichtung zur Konzentration und Amplifikation von Nukleinsäure in einer Einzelmikrokammer
EP1789592A4 (de) Verfahren zur identifizierung und quantifizierung von kurzen oder kleinen rna-molekülen
DE602006017332D1 (de) Verfahren und Vorrichtung zum Aufbrechen von Zellen und zur Aufreinigung von Nukleinsäure in einer einzelnen Kammer
ATE333519T1 (de) Electrochemisches verfahren zum nachweis von nukleinsäuren
ATE477488T1 (de) Verfahren zur bestimmung einer dna- bindungsprotein-menge

Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties