ATE522627T1 - Verfahren zur herstellung von nukleinsäuresonden - Google Patents

Verfahren zur herstellung von nukleinsäuresonden

Info

Publication number
ATE522627T1
ATE522627T1 AT07814636T AT07814636T ATE522627T1 AT E522627 T1 ATE522627 T1 AT E522627T1 AT 07814636 T AT07814636 T AT 07814636T AT 07814636 T AT07814636 T AT 07814636T AT E522627 T1 ATE522627 T1 AT E522627T1
Authority
AT
Austria
Prior art keywords
nucleic acid
acid probe
probes
producing nucleic
producing
Prior art date
Application number
AT07814636T
Other languages
English (en)
Inventor
Michael Farrell
Original Assignee
Ventana Med Syst Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ventana Med Syst Inc filed Critical Ventana Med Syst Inc
Application granted granted Critical
Publication of ATE522627T1 publication Critical patent/ATE522627T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6841—In situ hybridisation
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/70—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving virus or bacteriophage
    • C12Q1/701—Specific hybridization probes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/70—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving virus or bacteriophage
    • C12Q1/701—Specific hybridization probes
    • C12Q1/708—Specific hybridization probes for papilloma
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/112—Disease subtyping, staging or classification
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/156—Polymorphic or mutational markers

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Analytical Chemistry (AREA)
  • Immunology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Pathology (AREA)
  • Virology (AREA)
  • Hospice & Palliative Care (AREA)
  • Oncology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
AT07814636T 2006-09-01 2007-08-31 Verfahren zur herstellung von nukleinsäuresonden ATE522627T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US84189606P 2006-09-01 2006-09-01
US89257107P 2007-03-02 2007-03-02
PCT/US2007/077444 WO2008028156A2 (en) 2006-09-01 2007-08-31 Method for producing nucleic acid probes

Publications (1)

Publication Number Publication Date
ATE522627T1 true ATE522627T1 (de) 2011-09-15

Family

ID=39047618

Family Applications (1)

Application Number Title Priority Date Filing Date
AT07814636T ATE522627T1 (de) 2006-09-01 2007-08-31 Verfahren zur herstellung von nukleinsäuresonden

Country Status (7)

Country Link
US (3) US8420798B2 (de)
EP (1) EP2069537B1 (de)
AT (1) ATE522627T1 (de)
AU (1) AU2007289053B2 (de)
CA (1) CA2661713C (de)
ES (1) ES2372427T3 (de)
WO (1) WO2008028156A2 (de)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE522627T1 (de) * 2006-09-01 2011-09-15 Ventana Med Syst Inc Verfahren zur herstellung von nukleinsäuresonden
US7695929B2 (en) 2006-11-01 2010-04-13 Ventana Medical Systems, Inc. Haptens, hapten conjugates, compositions thereof and method for their preparation and use
US7682789B2 (en) 2007-05-04 2010-03-23 Ventana Medical Systems, Inc. Method for quantifying biomolecules conjugated to a nanoparticle
ES2731432T3 (es) 2007-05-23 2019-11-15 Ventana Med Syst Inc Transportadores poliméricos para inmunohistoquímica e hibridación in situ
DK2995925T3 (da) 2008-06-05 2022-02-21 Ventana Med Syst Inc Sammensætning til histokemisk processering
US9593366B2 (en) * 2008-10-30 2017-03-14 Qiagen Gaithersburg, Inc. Individually synthesized primers to be used in whole genome amplification
JP2012528569A (ja) 2009-05-29 2012-11-15 ヴェンタナ メディカル システムズ， インク． インサイツハイブリダイゼーションを使用した生物学試料の遺伝子コピー数のスコアリング法
WO2010138908A1 (en) 2009-05-29 2010-12-02 Ventana Medical Systems, Inc. Igfir gene copy number as a prognostic marker in a non-small cell lung cancer
EP2531569B1 (de) 2010-02-02 2017-01-25 Ventana Medical Systems, Inc. Zusammensetzung und verfahren zur stabilisierung fluoreszierender partikel
USPP22463P3 (en) * 2010-02-16 2012-01-17 Menachem Bornstein Gypsophila plant named ‘Pearl Blossom’
ES2606012T3 (es) 2010-02-26 2017-03-17 Ventana Medical Systems, Inc. Hibridación in situ con sondas PolyTag
JP5822913B2 (ja) 2010-04-20 2015-11-25 ヴェンタナ メディカル システムズ， インク． ２色発色性インサイツハイブリダイゼーション
WO2012024185A1 (en) 2010-08-16 2012-02-23 Ventana Medical Systems, Inc. Substrates for chromogenic detection and methods of use in detection assays and kits
US20120108451A1 (en) * 2010-10-29 2012-05-03 Simon Fraser University Methods and apparatus for nanoparticle-assisted nucleic acid hybridization and microarray analysis
CA2827429C (en) 2011-01-19 2020-03-24 Cb Biotechnologies, Inc. Polymerase preference index
US9448231B2 (en) 2011-02-28 2016-09-20 Ventana Medical Systems, Inc. Application of quantum dots for nuclear staining
CN103534359B (zh) 2011-03-14 2016-07-06 文塔纳医疗系统公司 分析染色体易位的方法及其系统
US10385392B2 (en) * 2011-12-30 2019-08-20 Abbott Molecular Inc. Nucleic acid hybridization probes
WO2013108126A2 (en) 2012-01-16 2013-07-25 University Of Oslo Methyltransferases and uses thereof
US9580746B2 (en) * 2013-03-05 2017-02-28 Agilent Technologies, Inc. Synthesis of long fish probes
CN104099409B (zh) * 2013-03-05 2020-07-17 安捷伦科技有限公司 长fish探针的合成
WO2016077426A1 (en) * 2014-11-11 2016-05-19 Abbott Molecular Inc. Hybridization probes and methods
CA3005430A1 (en) 2015-11-16 2017-05-26 Revere Biosensors, Llc Systems and methods for identifying and distinguishing genetic samples
US20230183780A1 (en) 2016-07-25 2023-06-15 InVivo BioTech Services GmbH Dna probes for in situ hybridization on chromosomes
US11345954B2 (en) 2016-08-05 2022-05-31 Arizona Board Of Regents On Behalf Of Arizona State University Methods for digital readout quantification of nucleic acids
CN110869512A (zh) 2017-05-09 2020-03-06 雷瑞生物传感器有限责任公司 鉴别并区分遗传样品的系统及方法
CN107603971B (zh) * 2017-10-24 2020-02-04 厦门龙进生物科技有限公司 一种原位杂交探针的制备方法
EP3931353A4 (de) 2019-03-01 2022-11-16 Revere Biosensors, LLC Systeme und verfahren zur trennung von decodierten arrays

Family Cites Families (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5447841A (en) * 1986-01-16 1995-09-05 The Regents Of The Univ. Of California Methods for chromosome-specific staining
US6280929B1 (en) * 1986-01-16 2001-08-28 The Regents Of The University Of California Method of detecting genetic translocations identified with chromosomal abnormalities
US5756696A (en) * 1986-01-16 1998-05-26 Regents Of The University Of California Compositions for chromosome-specific staining
US5834202A (en) * 1992-08-04 1998-11-10 Replicon, Inc. Methods for the isothermal amplification of nucleic acid molecules
US5731171A (en) * 1993-07-23 1998-03-24 Arch Development Corp. Sequence independent amplification of DNA
US5643761A (en) * 1993-10-27 1997-07-01 The Trustees Of Columbia University In The City Of New York Method for generating a subtracted cDNA library and uses of the generated library
US5648211A (en) * 1994-04-18 1997-07-15 Becton, Dickinson And Company Strand displacement amplification using thermophilic enzymes
US5648245A (en) * 1995-05-09 1997-07-15 Carnegie Institution Of Washington Method for constructing an oligonucleotide concatamer library by rolling circle replication
US5854033A (en) * 1995-11-21 1998-12-29 Yale University Rolling circle replication reporter systems
US6143495A (en) * 1995-11-21 2000-11-07 Yale University Unimolecular segment amplification and sequencing
WO1998015649A1 (en) * 1996-10-04 1998-04-16 Universität Heidelberg A method of purifying dna
US6124120A (en) * 1997-10-08 2000-09-26 Yale University Multiple displacement amplification
CA2375769A1 (en) * 1999-01-11 2000-07-20 President And Fellows Of Harvard College Isothermal amplification of dna
US6291187B1 (en) * 2000-05-12 2001-09-18 Molecular Staging, Inc. Poly-primed amplification of nucleic acid sequences
NZ522406A (en) 2000-05-16 2006-05-26 Childrens Mercy Hospital Single copy genomic hybridization probes and method of generating same
US6828097B1 (en) * 2000-05-16 2004-12-07 The Childrens Mercy Hospital Single copy genomic hybridization probes and method of generating same
US7763421B2 (en) * 2000-06-05 2010-07-27 Ventana Medical Systems, Inc. Methods for producing nucleic acid hybridization probes that amplify hybridization signal by promoting network formation
US6323009B1 (en) * 2000-06-28 2001-11-27 Molecular Staging, Inc. Multiply-primed amplification of nucleic acid sequences
US6942970B2 (en) * 2000-09-14 2005-09-13 Zymed Laboratories, Inc. Identifying subjects suitable for topoisomerase II inhibitor treatment
US20030022166A1 (en) * 2001-01-19 2003-01-30 Colin Collins Repeat-free probes for molecular cytogenetics
US6638722B2 (en) * 2001-06-13 2003-10-28 Invitrogen Corporation Method for rapid amplification of DNA
US6977148B2 (en) * 2001-10-15 2005-12-20 Qiagen Gmbh Multiple displacement amplification
US6617137B2 (en) * 2001-10-15 2003-09-09 Molecular Staging Inc. Method of amplifying whole genomes without subjecting the genome to denaturing conditions
US20050181394A1 (en) * 2003-06-20 2005-08-18 Illumina, Inc. Methods and compositions for whole genome amplification and genotyping
US20050048498A1 (en) * 2003-08-29 2005-03-03 Applera Corporation Compositions, methods, and kits for assembling probes
JP2007506429A (ja) * 2003-09-23 2007-03-22 アトム・サイエンシズ・インコーポレーテッド ポリマー核酸のハイブリダイゼーションプローブ
US20060110744A1 (en) * 2004-11-23 2006-05-25 Sampas Nicolas M Probe design methods and microarrays for comparative genomic hybridization and location analysis
US20060160116A1 (en) * 2004-12-16 2006-07-20 The Regents Of The University Of California Repetitive sequence-free DNA libraries
ATE522627T1 (de) 2006-09-01 2011-09-15 Ventana Med Syst Inc Verfahren zur herstellung von nukleinsäuresonden

Also Published As

Publication number Publication date
EP2069537B1 (de) 2011-08-31
CA2661713A1 (en) 2008-03-06
US20130183670A1 (en) 2013-07-18
US20080057513A1 (en) 2008-03-06
AU2007289053B2 (en) 2013-05-30
WO2008028156A2 (en) 2008-03-06
AU2007289053A1 (en) 2008-03-06
US9145585B2 (en) 2015-09-29
CA2661713C (en) 2016-08-02
EP2069537A2 (de) 2009-06-17
WO2008028156A3 (en) 2008-04-24
US8420798B2 (en) 2013-04-16
US8828659B2 (en) 2014-09-09
US20140342941A1 (en) 2014-11-20
ES2372427T3 (es) 2012-01-19

Similar Documents

Publication Publication Date Title
WO2008028156A3 (en) Method for producing nucleic acid probes
WO2010129019A3 (en) Real-time sequencing methods and systems
DE602006019261D1 (de) Verfahren zur sequenzierung einer polynukleotidmatrize
ATE474938T1 (de) Verfahren zur erhöhung der genauigkeit einer nukleinsäuresequenzierung
WO2010068289A3 (en) Classification of nucleic acid templates
WO2012065043A9 (en) Classification of nucleic acid templates
ATE533838T1 (de) Verfahren zur verbesserten einführung von dna in bakterienzellen
NZ582702A (en) Diagnosing fetal chromosomal aneuploidy using genomic sequencing
WO2006117596A3 (en) Nucleic acid probes and nucleic acid analog probes
ATE507309T1 (de) Verfahren zur erkennung eines oralen plattenepithelkarzinoms und mittel zu dessen unterdrückung
ATE548467T1 (de) Verfahren zur identifizierung von biomarkern mit eignung bei der diagnose biologischer zustände
ATE542803T1 (de) Verfahren zur herstellung von dihydrochinazolinen
EP2350013A4 (de) Zusammensetzungen zur markierung und identifizierung von autophagosomen sowie verfahren zu ihrer herstellung und verwendung
AT10182U2 (de) Verfahren zur überwachung von leistungsprüfständen, sowie leistungsprüfstand
BR112014026440A2 (pt) assays, methods and apparatus for assessing rna disruption
DE602006003880D1 (de) Verfahren zur herstellung von multimetallkatalysatoren, die bei kohlenwasserstoffumwandlungsreaktionen verwendet werden können
DE602007000378D1 (de) Verfahren und Vorrichtung zur Überprüfung der Integrität eines Wartungszusammenhangs sowie Verfahren und Vorrichtung zum Einfügen eines Wartungsendpunktes
ATE519116T1 (de) Verfahren zur normierung der konzentration von analyten in einer urinprobe
ATE446384T1 (de) Verfahren zur amplifikation von nukleinsäuren mittels promotor-templates
ATE456666T1 (de) Verfahren zur auswertung von ribonukleotidsequenzen
DE502004007244D1 (de) Verfahren zum spezifischen schnellnachweis getr nkesch dlicher mikroorganismen
ATE544474T1 (de) Magnetresonanz-abbildungsmittel, abbildungsmedium und verfahren zur abbildung, worin solch ein abbildungsmedium verwendet wird
WO2007113575A3 (en) Reagents and methods for cross-linking biological molecules
ATE507304T1 (de) Nachweis von chromosomalen anormalitäten in aus follikularer flüssigkeit erhaltenen zellen
ATE340873T1 (de) Verfahren zur durchführung einer subtraktiven hybridisierung

Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties