ATE489077T1 - Schnell lösliche formulierung von nichtsteroidalen antiphlogistika - Google Patents

Schnell lösliche formulierung von nichtsteroidalen antiphlogistika

Info

Publication number
ATE489077T1
ATE489077T1 AT06121457T AT06121457T ATE489077T1 AT E489077 T1 ATE489077 T1 AT E489077T1 AT 06121457 T AT06121457 T AT 06121457T AT 06121457 T AT06121457 T AT 06121457T AT E489077 T1 ATE489077 T1 AT E489077T1
Authority
AT
Austria
Prior art keywords
nsaid
soluble formulation
quickly soluble
steroidal antiphlogistics
base
Prior art date
Application number
AT06121457T
Other languages
English (en)
Inventor
Peter Gruber
Peter Kraahs
Original Assignee
Losan Pharma Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Losan Pharma Gmbh filed Critical Losan Pharma Gmbh
Application granted granted Critical
Publication of ATE489077T1 publication Critical patent/ATE489077T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/143—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/192—Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid 
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1611—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Inorganic Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
AT06121457T 2006-09-28 2006-09-28 Schnell lösliche formulierung von nichtsteroidalen antiphlogistika ATE489077T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP06121457A EP1905427B1 (de) 2006-09-28 2006-09-28 Schnell lösliche Formulierung von nichtsteroidalen Antiphlogistika

Publications (1)

Publication Number Publication Date
ATE489077T1 true ATE489077T1 (de) 2010-12-15

Family

ID=37685214

Family Applications (1)

Application Number Title Priority Date Filing Date
AT06121457T ATE489077T1 (de) 2006-09-28 2006-09-28 Schnell lösliche formulierung von nichtsteroidalen antiphlogistika

Country Status (12)

Country Link
US (1) US20100035937A1 (de)
EP (1) EP1905427B1 (de)
CN (1) CN101522175A (de)
AT (1) ATE489077T1 (de)
AU (1) AU2007302163A1 (de)
BR (1) BRPI0717279A2 (de)
CA (1) CA2664773A1 (de)
DE (1) DE602006018467D1 (de)
ES (1) ES2353900T3 (de)
PL (1) PL1905427T3 (de)
RU (1) RU2009109071A (de)
WO (1) WO2008037557A2 (de)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PT2559430E (pt) 2005-03-22 2015-10-09 Stada Arzneimittel Ag Ibuprofeno solubilizado
EP2608772A2 (de) * 2010-08-23 2013-07-03 President and Fellows of Harvard College Partikel für wirkstofffreisetzung und andere anwendung
US9695390B2 (en) 2010-08-23 2017-07-04 President And Fellows Of Harvard College Acoustic waves in microfluidics
JP6194248B2 (ja) 2010-10-28 2017-09-06 パシラ ファーマシューティカルズ インコーポレーテッド 非ステロイド性抗炎症薬の徐放性処方物
RU2502507C2 (ru) * 2011-09-02 2013-12-27 Людмила Васильевна Безпалько Фармацевтическая композиция с противовоспалительной, кардио- и хондропротекторной активностью, действием против гастропатий, вызываемых нпвп, и способ ее получения
US9138381B2 (en) 2013-02-08 2015-09-22 Basf Se Production of inorganic-organic composite materials by reactive spray-drying
JP2016507542A (ja) 2013-02-08 2016-03-10 ビーエーエスエフ ソシエタス・ヨーロピアＢａｓｆ Ｓｅ 反応型噴霧乾燥による無機／有機複合材料の製造
WO2015200616A1 (en) 2014-06-26 2015-12-30 President And Fellows Of Harvard College Fluid injection using acoustic waves
CN108472621B (zh) 2015-08-27 2022-04-29 哈佛学院院长及董事 声波分拣
GB2546513B (en) * 2016-01-20 2020-09-16 Cubic Pharmaceuticals Ltd Process of preparing active pharmaceutical ingredient salts
CN106361756B (zh) * 2016-08-30 2019-01-15 山东百维药业有限公司 一种氨糖美辛肠溶片及其制备方法
EP3541815A4 (de) 2016-11-18 2020-07-15 Pacira Pharmaceuticals, Inc. Multivesikuläre liposomenformulierung mit zinkmeloxicamkomplex-mikropartikeln und verfahren zur herstellung davon
CN106361714A (zh) * 2016-11-24 2017-02-01 江苏中邦制药有限公司 一种含萘普生的药物组合物的制备方法
WO2018111459A1 (en) * 2016-12-14 2018-06-21 Dow Global Technologies Llc Method for generating salts of pharmaceutical active ingredients
CN111494307A (zh) * 2019-01-30 2020-08-07 北京普德康利医药科技发展有限公司 一种氟比洛芬注射液
US11701658B2 (en) 2019-08-09 2023-07-18 President And Fellows Of Harvard College Systems and methods for microfluidic particle selection, encapsulation, and injection using surface acoustic waves

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5183829A (en) * 1991-09-27 1993-02-02 Applied Analytical Industries, Inc. Oral liquid compositions of non-steroidal anti-inflammatory drugs
IT1272149B (it) 1993-03-26 1997-06-11 Zambon Spa Composizione farmeceutiche ad attivita' analgesica
WO1997018245A1 (en) 1995-11-14 1997-05-22 Farmarc Nederland B.V. Complex of naproxen and beta-cyclodextrin
DE19606151C2 (de) 1996-02-20 1999-05-12 Losan Pharma Gmbh Ibuprofen-Brausezubereitung sowie Verfahren zur Herstellung derselben
DE19624607A1 (de) * 1996-06-20 1998-01-02 Basf Ag Verfahren zur Herstellung von Salzen von Säuregruppen tragenden pharmazeutischen Wirkstoffen
CA2301304A1 (en) * 1997-08-27 1999-03-04 Hexal Ag New pharmaceutical compositions of meloxicam with improved solubility and bioavailability
US6165506A (en) 1998-09-04 2000-12-26 Elan Pharma International Ltd. Solid dose form of nanoparticulate naproxen
US8124124B2 (en) 1999-12-09 2012-02-28 Reckitt Benckiser Healthcare (Uk) Limited Compressed tablet formulation comprising non-steroidal anti-inflammatory drugs and methods
CA2363528A1 (en) 2001-11-19 2003-05-19 Merck Patent Gesellschaft Mit Beschraenkter Haftung Immediate release tablet containing naproxen sodium
SE0200154D0 (sv) 2002-01-21 2002-01-21 Galenica Ab New process
EP1800667A1 (de) * 2005-12-23 2007-06-27 Losan Pharma GmbH Schnell lösliches Ibuprofen-Granulat

Also Published As

Publication number Publication date
PL1905427T3 (pl) 2011-05-31
BRPI0717279A2 (pt) 2013-10-22
EP1905427A1 (de) 2008-04-02
DE602006018467D1 (de) 2011-01-05
WO2008037557A3 (en) 2008-07-03
CN101522175A (zh) 2009-09-02
AU2007302163A1 (en) 2008-04-03
WO2008037557A2 (en) 2008-04-03
ES2353900T3 (es) 2011-03-08
CA2664773A1 (en) 2008-04-03
US20100035937A1 (en) 2010-02-11
RU2009109071A (ru) 2010-11-10
EP1905427B1 (de) 2010-11-24

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