ATE489106T1 - Virusähnliche partikel, verfahren zur herstellung und immunogene zusammensetzungen - Google Patents

Virusähnliche partikel, verfahren zur herstellung und immunogene zusammensetzungen

Info

Publication number
ATE489106T1
ATE489106T1 AT03808386T AT03808386T ATE489106T1 AT E489106 T1 ATE489106 T1 AT E489106T1 AT 03808386 T AT03808386 T AT 03808386T AT 03808386 T AT03808386 T AT 03808386T AT E489106 T1 ATE489106 T1 AT E489106T1
Authority
AT
Austria
Prior art keywords
vlp
virus
particles
viral
immunogenic compositions
Prior art date
Application number
AT03808386T
Other languages
English (en)
Inventor
Richard Compans
Chinglai Yang
Qizhi Yao
Sang-Moo Kang
Original Assignee
Univ Emory
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Emory filed Critical Univ Emory
Priority claimed from PCT/US2003/015930 external-priority patent/WO2004042001A2/en
Application granted granted Critical
Publication of ATE489106T1 publication Critical patent/ATE489106T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/51Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/525Virus
    • A61K2039/5258Virus-like particles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/545Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/555Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511Organic adjuvants
    • A61K2039/55516Proteins; Peptides
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2740/00Reverse transcribing RNA viruses
    • C12N2740/00011Details
    • C12N2740/10011Retroviridae
    • C12N2740/10023Virus like particles [VLP]
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2740/00Reverse transcribing RNA viruses
    • C12N2740/00011Details
    • C12N2740/10011Retroviridae
    • C12N2740/15011Lentivirus, not HIV, e.g. FIV, SIV
    • C12N2740/15023Virus like particles [VLP]
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2740/00Reverse transcribing RNA viruses
    • C12N2740/00011Details
    • C12N2740/10011Retroviridae
    • C12N2740/16011Human Immunodeficiency Virus, HIV
    • C12N2740/16023Virus like particles [VLP]
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2810/00Vectors comprising a targeting moiety
    • C12N2810/50Vectors comprising as targeting moiety peptide derived from defined protein
    • C12N2810/60Vectors comprising as targeting moiety peptide derived from defined protein from viruses
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2810/00Vectors comprising a targeting moiety
    • C12N2810/50Vectors comprising as targeting moiety peptide derived from defined protein
    • C12N2810/60Vectors comprising as targeting moiety peptide derived from defined protein from viruses
    • C12N2810/6045RNA rev transcr viruses
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2810/00Vectors comprising a targeting moiety
    • C12N2810/50Vectors comprising as targeting moiety peptide derived from defined protein
    • C12N2810/60Vectors comprising as targeting moiety peptide derived from defined protein from viruses
    • C12N2810/6072Vectors comprising as targeting moiety peptide derived from defined protein from viruses negative strand RNA viruses
    • C12N2810/6081Vectors comprising as targeting moiety peptide derived from defined protein from viruses negative strand RNA viruses rhabdoviridae, e.g. VSV

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Virology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
AT03808386T 2002-05-17 2003-05-19 Virusähnliche partikel, verfahren zur herstellung und immunogene zusammensetzungen ATE489106T1 (de)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US38155702P 2002-05-17 2002-05-17
US45411503P 2003-03-11 2003-03-11
US45413903P 2003-03-11 2003-03-11
US45458403P 2003-03-14 2003-03-14
US46831803P 2003-05-06 2003-05-06
US47124603P 2003-05-16 2003-05-16
PCT/US2003/015930 WO2004042001A2 (en) 2002-05-17 2003-05-19 Virus-like particles, methods of preparation, and immonogenic compositions

Publications (1)

Publication Number Publication Date
ATE489106T1 true ATE489106T1 (de) 2010-12-15

Family

ID=34199380

Family Applications (1)

Application Number Title Priority Date Filing Date
AT03808386T ATE489106T1 (de) 2002-05-17 2003-05-19 Virusähnliche partikel, verfahren zur herstellung und immunogene zusammensetzungen

Country Status (5)

Country Link
EP (1) EP1576143B1 (de)
AT (1) ATE489106T1 (de)
AU (1) AU2003301844A1 (de)
CA (1) CA2486282C (de)
DE (1) DE60335139D1 (de)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2044198A4 (de) * 2006-07-27 2010-09-08 Ligocyte Pharmaceuticals Inc Chimärische influenza-virus-ähnliche partikel
CN108348596B (zh) * 2015-07-02 2022-08-23 梅迪根股份有限公司 用牛免疫缺陷病毒Gag蛋白的重组病毒样颗粒
CN116024269B (zh) * 2022-11-18 2024-02-02 复百澳(苏州)生物医药科技有限公司 一种冠状病毒假病毒颗粒的制备方法
CN119954915B (zh) * 2025-02-13 2026-02-03 杭州恒奥科技有限公司 禽流感病毒快速检测试纸条及其制备方法和应用

Also Published As

Publication number Publication date
CA2486282C (en) 2012-04-10
AU2003301844A1 (en) 2004-06-07
EP1576143A2 (de) 2005-09-21
EP1576143A4 (de) 2007-08-08
CA2486282A1 (en) 2004-05-21
EP1576143B1 (de) 2010-11-24
DE60335139D1 (de) 2011-01-05

Similar Documents

Publication Publication Date Title
WO2004042001A3 (en) Virus-like particles, methods of preparation, and immonogenic compositions
WO2007019247A3 (en) Virus-like particles as vaccines for paramyxovirus
WO2000032227A3 (en) Ordered molecular presentation of antigens, method of preparation and use
ATE384785T1 (de) Herstellung von viren, virusisolaten, und impfstoffen
DE69835294D1 (de) Methode zur in vitro auseinander- und wiederzusammensetzung von papillomavirus virus-ähnlichen tielchen (vlps)
DE69535018D1 (de) Papillomavirus vakzine
WO2005055957A3 (en) Influenza immunogen and vaccine
WO2002024876A3 (en) Live influenza vaccine and method of manufacture
AU5998400A (en) In vitro reconstitution of segmented negative-strand rna viruses
WO2007011904A3 (en) Recombinant flu vaccines
BR0113577A (pt) Empacotamento de partìculas de replicon de vìrus de rna de filamento positivo
WO2004113517A3 (en) IMPROVED METHOD FOR THE RECOVERY OF NON-SEGMENTED, NEGATIVE-STRANDED RNA VIRUSES FROM cDNA
WO2004001051A3 (en) Recombinant measles viruses expressing epitopes pf antigens of rna viruses and use of the recombinant viruses for the preparation of vaccine compositions
EP2272525A3 (de) Virusteilchenadjuvans
PH12020552252A1 (en) Influenza virus hemagglutinin mutants
JP2009501001A5 (de)
WO2009014782A3 (en) Improved production and in vivo assembly of soluble recombinant icosahedral virus-like particles
WO2003031583A3 (en) Generation of virus-like particles by vsv
EP1013757A3 (de) Abgeschwächte Formen des Rinderdiarrhöevirus
WO2003072725A3 (en) Recombinant negative strand virus rna expression systems and vaccines
ATE489106T1 (de) Virusähnliche partikel, verfahren zur herstellung und immunogene zusammensetzungen
MXPA02012593A (es) Particulas de tipo virus del virus de la diarrea viral bovina.
DE60222296D1 (de) Impfstoff von umhüllten viren und verfahren zu seiner herstellung
AU2003261977A1 (en) Hbv precore protein capable of forming particles
ATE427119T1 (de) Rekombinante tollwut-vakzine und verfahren zu ihrer herstellung und verwendung

Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties