ATE489391T1 - Neue 4-amino-3-(-azolylphenoxymethyl)thienoä3,2- cüpyridin-7-carbonsäurederivate - Google Patents

Neue 4-amino-3-(-azolylphenoxymethyl)thienoä3,2- cüpyridin-7-carbonsäurederivate

Info

Publication number
ATE489391T1
ATE489391T1 AT07730300T AT07730300T ATE489391T1 AT E489391 T1 ATE489391 T1 AT E489391T1 AT 07730300 T AT07730300 T AT 07730300T AT 07730300 T AT07730300 T AT 07730300T AT E489391 T1 ATE489391 T1 AT E489391T1
Authority
AT
Austria
Prior art keywords
thienoä3
cupyridine
azolylphenoxymethyl
amino
new
Prior art date
Application number
AT07730300T
Other languages
English (en)
Inventor
Yi Chen
Kin-Chun Thomas Luk
Pamela Loreen Rossman
Sung-Sau So
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Application granted granted Critical
Publication of ATE489391T1 publication Critical patent/ATE489391T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D495/00Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/4365Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system having sulfur as a ring hetero atom, e.g. ticlopidine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Epidemiology (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Materials For Medical Uses (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
AT07730300T 2006-06-29 2007-06-22 Neue 4-amino-3-(-azolylphenoxymethyl)thienoä3,2- cüpyridin-7-carbonsäurederivate ATE489391T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US81761606P 2006-06-29 2006-06-29
PCT/EP2007/056241 WO2008000697A1 (en) 2006-06-29 2007-06-22 Novel 4-amino-3-(-azolyl-phenoxymethyl)-thieno[3,2]pyridine-7-carboxylic acid derivatives

Publications (1)

Publication Number Publication Date
ATE489391T1 true ATE489391T1 (de) 2010-12-15

Family

ID=38514272

Family Applications (1)

Application Number Title Priority Date Filing Date
AT07730300T ATE489391T1 (de) 2006-06-29 2007-06-22 Neue 4-amino-3-(-azolylphenoxymethyl)thienoä3,2- cüpyridin-7-carbonsäurederivate

Country Status (16)

Country Link
US (1) US7932390B2 (de)
EP (1) EP2038288B1 (de)
JP (1) JP4933617B2 (de)
KR (1) KR101143286B1 (de)
CN (1) CN101479278B (de)
AT (1) ATE489391T1 (de)
BR (1) BRPI0713041A8 (de)
CA (1) CA2655398C (de)
DE (1) DE602007010779D1 (de)
DK (1) DK2038288T3 (de)
ES (1) ES2354637T3 (de)
IL (1) IL195897A (de)
MX (1) MX2008016068A (de)
PL (1) PL2038288T3 (de)
PT (1) PT2038288E (de)
WO (1) WO2008000697A1 (de)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9540322B2 (en) 2008-08-18 2017-01-10 Yale University MIF modulators
US8957216B2 (en) * 2010-03-24 2015-02-17 Amitech Therapeutic Solutions, Inc. Heterocyclic compounds useful for kinase inhibition
US12378229B2 (en) 2021-02-02 2025-08-05 Liminal Biosciences Limited GPR84 antagonists and uses thereof

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2732970B1 (fr) * 1995-04-14 1997-05-16 Hoechst Schering Agrevo Sa Nouveaux derives de l'acide beta-methoxy acrylique, leur procede de preparation et leur application comme pesticides
UA60365C2 (uk) 1998-06-04 2003-10-15 Пфайзер Продактс Інк. Похідні ізотіазолу, спосіб їх одержання, фармацевтична композиція та спосіб лікування гіперпроліферативного захворювання у ссавця
US6232320B1 (en) * 1998-06-04 2001-05-15 Abbott Laboratories Cell adhesion-inhibiting antiinflammatory compounds
HN2000000051A (es) 1999-05-19 2001-02-02 Pfizer Prod Inc Derivados heterociclicos utiles como agentes anticancerosos
IL155371A0 (en) 2000-11-28 2003-11-23 Pfizer Prod Inc Salts of a isothiazole-4-carboxamide and their use as anti-hyperproliferation agents
WO2003082272A1 (en) 2002-03-29 2003-10-09 Chiron Corporation Substituted benzazoles and use thereof as raf kinase inhibitors
WO2004041285A1 (en) * 2002-10-31 2004-05-21 Amgen Inc. Antiinflammation agents
WO2004100947A2 (en) 2003-05-06 2004-11-25 Smithkline Beecham Corporation Novel chemical compounds
US7202363B2 (en) * 2003-07-24 2007-04-10 Abbott Laboratories Thienopyridine and furopyridine kinase inhibitors
US20050026944A1 (en) * 2003-07-24 2005-02-03 Patrick Betschmann Thienopyridine and furopyridine kinase inhibitors
US20050020619A1 (en) * 2003-07-24 2005-01-27 Patrick Betschmann Thienopyridine kinase inhibitors
JP4557984B2 (ja) 2003-12-05 2010-10-06 ベーリンガー インゲルハイム ファーマシューティカルズ インコーポレイテッド Ikkインヒビターとしての置換3−アミノ−チエノ−[2,3−b]ピリジン−2−カルボン酸アミド化合物
US20050256154A1 (en) * 2004-05-04 2005-11-17 Kin-Chun Luk 4-Amino-thieno[3,2-c]pyridine-7-carboxylic acid amides

Also Published As

Publication number Publication date
BRPI0713041A2 (pt) 2012-04-17
CA2655398C (en) 2014-07-29
DE602007010779D1 (en) 2011-01-05
CA2655398A1 (en) 2008-01-03
PL2038288T3 (pl) 2011-05-31
EP2038288B1 (de) 2010-11-24
WO2008000697A1 (en) 2008-01-03
MX2008016068A (es) 2009-01-15
JP4933617B2 (ja) 2012-05-16
CN101479278B (zh) 2011-12-07
EP2038288A1 (de) 2009-03-25
AU2007263770A1 (en) 2008-01-03
US7932390B2 (en) 2011-04-26
DK2038288T3 (da) 2011-01-03
BRPI0713041A8 (pt) 2019-01-15
US20080009515A1 (en) 2008-01-10
IL195897A0 (en) 2009-09-01
PT2038288E (pt) 2011-01-12
KR20090021195A (ko) 2009-02-27
ES2354637T3 (es) 2011-03-16
KR101143286B1 (ko) 2012-05-24
CN101479278A (zh) 2009-07-08
IL195897A (en) 2016-04-21
JP2009541424A (ja) 2009-11-26

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