ATE489401T1 - Pegyliertes t20-polypeptid - Google Patents

Pegyliertes t20-polypeptid

Info

Publication number
ATE489401T1
ATE489401T1 AT03766190T AT03766190T ATE489401T1 AT E489401 T1 ATE489401 T1 AT E489401T1 AT 03766190 T AT03766190 T AT 03766190T AT 03766190 T AT03766190 T AT 03766190T AT E489401 T1 ATE489401 T1 AT E489401T1
Authority
AT
Austria
Prior art keywords
pegylated
polypeptide
Prior art date
Application number
AT03766190T
Other languages
English (en)
Inventor
Pascal Bailon
Chee-Youb Won
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Application granted granted Critical
Publication of ATE489401T1 publication Critical patent/ATE489401T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • C07K14/08RNA viruses
    • C07K14/15Retroviridae, e.g. bovine leukaemia virus, feline leukaemia virus human T-cell leukaemia-lymphoma virus
    • C07K14/155Lentiviridae, e.g. human immunodeficiency virus [HIV], visna-maedi virus or equine infectious anaemia virus
    • C07K14/16HIV-1 ; HIV-2
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • A61P31/18Antivirals for RNA viruses for HIV
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2740/00Reverse transcribing RNA viruses
    • C12N2740/00011Details
    • C12N2740/10011Retroviridae
    • C12N2740/16011Human Immunodeficiency Virus, HIV
    • C12N2740/16111Human Immunodeficiency Virus, HIV concerning HIV env
    • C12N2740/16122New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Virology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Oncology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Communicable Diseases (AREA)
  • AIDS & HIV (AREA)
  • Immunology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Toxicology (AREA)
  • Epidemiology (AREA)
  • Hematology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AT03766190T 2002-07-24 2003-07-16 Pegyliertes t20-polypeptid ATE489401T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US39819502P 2002-07-24 2002-07-24
PCT/EP2003/007710 WO2004013164A1 (en) 2002-07-24 2003-07-16 Pegylated t20 polypeptide

Publications (1)

Publication Number Publication Date
ATE489401T1 true ATE489401T1 (de) 2010-12-15

Family

ID=31495720

Family Applications (1)

Application Number Title Priority Date Filing Date
AT03766190T ATE489401T1 (de) 2002-07-24 2003-07-16 Pegyliertes t20-polypeptid

Country Status (24)

Country Link
US (1) US7049415B2 (de)
EP (1) EP1527088B1 (de)
JP (1) JP4381301B2 (de)
KR (1) KR100637981B1 (de)
CN (1) CN100357317C (de)
AR (1) AR040651A1 (de)
AT (1) ATE489401T1 (de)
AU (1) AU2003257467B2 (de)
BR (1) BR0312889A (de)
CA (1) CA2493534C (de)
DE (1) DE60335111D1 (de)
ES (1) ES2354609T3 (de)
GT (1) GT200300155A (de)
HR (1) HRP20050024A2 (de)
IL (2) IL166038A0 (de)
MX (1) MXPA05000797A (de)
NO (1) NO20050066L (de)
PA (1) PA8577701A1 (de)
PE (1) PE20040705A1 (de)
PL (1) PL375254A1 (de)
RU (1) RU2296769C2 (de)
TW (1) TW200416225A (de)
WO (1) WO2004013164A1 (de)
ZA (1) ZA200500258B (de)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6057287A (en) 1994-01-11 2000-05-02 Dyax Corp. Kallikrein-binding "Kunitz domain" proteins and analogues thereof
US7153829B2 (en) 2002-06-07 2006-12-26 Dyax Corp. Kallikrein-inhibitor therapies
ES2348230T3 (es) * 2002-06-07 2010-12-01 Dyax Corp. Prevención y reducción de la isquemia.
US20050089515A1 (en) * 2003-08-29 2005-04-28 Dyax Corp. Poly-pegylated protease inhibitors
AU2004268144A1 (en) * 2003-08-29 2005-03-10 Dyax Corp. Modified protease inhibitors
KR101276422B1 (ko) * 2004-03-15 2013-06-19 넥타르 테라퓨틱스 Hiv 유입 억제제의 중합체-기재 조성물 및 콘쥬게이트
US7235530B2 (en) 2004-09-27 2007-06-26 Dyax Corporation Kallikrein inhibitors and anti-thrombolytic agents and uses thereof
ES2336245T3 (es) * 2005-04-08 2010-04-09 Lonza Ag Sintesis peptidica de helices alfa sobre resina de peg.
US20090075887A1 (en) * 2007-08-21 2009-03-19 Genzyme Corporation Treatment with Kallikrein Inhibitors
US8637454B2 (en) 2009-01-06 2014-01-28 Dyax Corp. Treatment of mucositis with kallikrein inhibitors
SMT201800552T1 (it) 2010-01-06 2018-11-09 Dyax Corp Proteine che legano la callicreina plasmatica
KR102320178B1 (ko) 2011-01-06 2021-11-02 다케다 파머수티컬 컴패니 리미티드 혈장 칼리크레인 결합 단백질
US10428158B2 (en) 2014-03-27 2019-10-01 Dyax Corp. Compositions and methods for treatment of diabetic macular edema
US20160151511A1 (en) 2014-12-02 2016-06-02 Antriabio, Inc. Proteins and protein conjugates with increased hydrophobicity
EP3387018A1 (de) 2015-12-11 2018-10-17 Dyax Corp. Plasma-kallikrein-inhibitoren und verwendungen davon zur behandlung von hereditärem angioödem
EP4090427A1 (de) 2020-01-13 2022-11-23 Takeda Pharmaceutical Company Limited Plasma-kallikrein-inhibitoren und verwendungen davon zur pädiatrischen behandlung von hereditärem angioödem

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US153694A (en) * 1874-08-04 Improvement in clothes-pounders
KR850004274A (ko) 1983-12-13 1985-07-11 원본미기재 에리트로포이에틴의 제조방법
US5252714A (en) 1990-11-28 1993-10-12 The University Of Alabama In Huntsville Preparation and use of polyethylene glycol propionaldehyde
US5464933A (en) * 1993-06-07 1995-11-07 Duke University Synthetic peptide inhibitors of HIV transmission
US5795569A (en) * 1994-03-31 1998-08-18 Amgen Inc. Mono-pegylated proteins that stimulate megakaryocyte growth and differentiation
CH690143A5 (de) 1995-01-27 2000-05-15 Rieter Automotive Int Ag Lambda/4-Schallabsorber.
US5672662A (en) 1995-07-07 1997-09-30 Shearwater Polymers, Inc. Poly(ethylene glycol) and related polymers monosubstituted with propionic or butanoic acids and functional derivatives thereof for biotechnical applications
US5990237A (en) 1997-05-21 1999-11-23 Shearwater Polymers, Inc. Poly(ethylene glycol) aldehyde hydrates and related polymers and applications in modifying amines
US6281331B1 (en) 1998-03-23 2001-08-28 Trimeris, Inc. Methods and compositions for peptide synthesis
WO1999048513A1 (en) * 1998-03-23 1999-09-30 Trimeris, Inc. Methods and compositions for peptide synthesis
AU1325400A (en) 1998-10-26 2000-05-15 University Of Utah Research Foundation Method for preparation of polyethylene glycol aldehyde derivatives
EP1135493A2 (de) * 1998-11-30 2001-09-26 Eli Lilly And Company Erythropoietische substanzen
JO2291B1 (en) * 1999-07-02 2005-09-12 اف . هوفمان لاروش ايه جي Erythropoietin derivatives
RU2179980C2 (ru) * 2000-03-20 2002-02-27 Государственный научный центр вирусологии и биотехнологии "Вектор" Пептид-имитатор консервативного эпитопа белка gp41 вируса иммунодефицита человека типа 1, узнаваемого вируснейтрализующими моноклональными антителами 2f5 (варианты)
KR100488351B1 (ko) 2001-12-11 2005-05-11 선바이오(주) 신규한 폴리에틸렌글리콜-프로피온알데히드 유도체

Also Published As

Publication number Publication date
KR100637981B1 (ko) 2006-10-23
US20040049018A1 (en) 2004-03-11
PL375254A1 (en) 2005-11-28
PE20040705A1 (es) 2004-10-14
IL166038A (en) 2010-11-30
EP1527088A1 (de) 2005-05-04
AR040651A1 (es) 2005-04-13
CN100357317C (zh) 2007-12-26
CA2493534A1 (en) 2004-02-12
RU2005105577A (ru) 2005-10-27
ZA200500258B (en) 2006-01-25
JP4381301B2 (ja) 2009-12-09
PA8577701A1 (es) 2004-02-07
GT200300155A (es) 2004-03-15
RU2296769C2 (ru) 2007-04-10
KR20050027257A (ko) 2005-03-18
TW200416225A (en) 2004-09-01
WO2004013164A1 (en) 2004-02-12
BR0312889A (pt) 2005-06-14
IL166038A0 (en) 2006-01-15
AU2003257467A1 (en) 2004-02-23
MXPA05000797A (es) 2005-04-19
CA2493534C (en) 2010-01-26
ES2354609T3 (es) 2011-03-16
DE60335111D1 (de) 2011-01-05
NO20050066L (no) 2005-04-22
JP2006511455A (ja) 2006-04-06
AU2003257467B2 (en) 2008-02-28
EP1527088B1 (de) 2010-11-24
CN1671736A (zh) 2005-09-21
US7049415B2 (en) 2006-05-23
HRP20050024A2 (en) 2006-02-28

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