ATE489401T1 - Pegyliertes t20-polypeptid - Google Patents

Pegyliertes t20-polypeptid

Info

Publication number
ATE489401T1
ATE489401T1 AT03766190T AT03766190T ATE489401T1 AT E489401 T1 ATE489401 T1 AT E489401T1 AT 03766190 T AT03766190 T AT 03766190T AT 03766190 T AT03766190 T AT 03766190T AT E489401 T1 ATE489401 T1 AT E489401T1
Authority
AT
Austria
Prior art keywords
pegylated
polypeptide
Prior art date
Application number
AT03766190T
Other languages
English (en)
Inventor
Pascal Bailon
Chee-Youb Won
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Application granted granted Critical
Publication of ATE489401T1 publication Critical patent/ATE489401T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • C07K14/08—RNA viruses
    • C07K14/15—Retroviridae, e.g. bovine leukaemia virus, feline leukaemia virus human T-cell leukaemia-lymphoma virus
    • C07K14/155—Lentiviridae, e.g. human immunodeficiency virus [HIV], visna-maedi virus or equine infectious anaemia virus
    • C07K14/16—HIV-1 ; HIV-2
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2740/00—Reverse transcribing RNA viruses
    • C12N2740/00011—Details
    • C12N2740/10011—Retroviridae
    • C12N2740/16011—Human Immunodeficiency Virus, HIV
    • C12N2740/16111—Human Immunodeficiency Virus, HIV concerning HIV env
    • C12N2740/16122—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Virology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Oncology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Communicable Diseases (AREA)
  • AIDS & HIV (AREA)
  • Immunology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Toxicology (AREA)
  • Epidemiology (AREA)
  • Hematology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AT03766190T 2002-07-24 2003-07-16 Pegyliertes t20-polypeptid ATE489401T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US39819502P 2002-07-24 2002-07-24
PCT/EP2003/007710 WO2004013164A1 (en) 2002-07-24 2003-07-16 Pegylated t20 polypeptide

Publications (1)

Publication Number Publication Date
ATE489401T1 true ATE489401T1 (de) 2010-12-15

Family

ID=31495720

Family Applications (1)

Application Number Title Priority Date Filing Date
AT03766190T ATE489401T1 (de) 2002-07-24 2003-07-16 Pegyliertes t20-polypeptid

Country Status (24)

Country Link
US (1) US7049415B2 (de)
EP (1) EP1527088B1 (de)
JP (1) JP4381301B2 (de)
KR (1) KR100637981B1 (de)
CN (1) CN100357317C (de)
AR (1) AR040651A1 (de)
AT (1) ATE489401T1 (de)
AU (1) AU2003257467B2 (de)
BR (1) BR0312889A (de)
CA (1) CA2493534C (de)
DE (1) DE60335111D1 (de)
ES (1) ES2354609T3 (de)
GT (1) GT200300155A (de)
HR (1) HRP20050024A2 (de)
IL (2) IL166038A0 (de)
MX (1) MXPA05000797A (de)
NO (1) NO20050066L (de)
PA (1) PA8577701A1 (de)
PE (1) PE20040705A1 (de)
PL (1) PL375254A1 (de)
RU (1) RU2296769C2 (de)
TW (1) TW200416225A (de)
WO (1) WO2004013164A1 (de)
ZA (1) ZA200500258B (de)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6057287A (en) 1994-01-11 2000-05-02 Dyax Corp. Kallikrein-binding "Kunitz domain" proteins and analogues thereof
CA2488558C (en) 2002-06-07 2013-08-20 Dyax Corp. Prevention and reduction of blood loss
US7153829B2 (en) 2002-06-07 2006-12-26 Dyax Corp. Kallikrein-inhibitor therapies
DK1663281T3 (en) * 2003-08-29 2014-03-17 Dyax Corp POLY-PEGYLED PROTEASE INHIBITORS
EP1663279A4 (de) * 2003-08-29 2009-02-18 Dyax Corp Modifizierte proteasehemmer
JP4805911B2 (ja) * 2004-03-15 2011-11-02 ネクター セラピューティクス Ｈｉｖ侵入阻害剤のポリマー系組成物及び複合体
US7235530B2 (en) 2004-09-27 2007-06-26 Dyax Corporation Kallikrein inhibitors and anti-thrombolytic agents and uses thereof
ATE448240T1 (de) * 2005-04-08 2009-11-15 Lonza Ag Peptidsynthese von alpha-helices auf peg-harz
EP2195010A4 (de) * 2007-08-21 2012-03-14 Genzyme Corp Behandlung mit kallikrein-inhibitoren
US8637454B2 (en) 2009-01-06 2014-01-28 Dyax Corp. Treatment of mucositis with kallikrein inhibitors
RS62853B1 (sr) 2010-01-06 2022-02-28 Takeda Pharmaceuticals Co Proteini koji vezuju kalikrein plazme
AU2012204202A1 (en) 2011-01-06 2013-07-11 Dyax Corp. Plasma kallikrein binding proteins
AU2015235967B2 (en) 2014-03-27 2020-10-22 Takeda Pharmaceutical Company Limited Compositions and methods for treatment of diabetic macular edema
US20160151511A1 (en) 2014-12-02 2016-06-02 Antriabio, Inc. Proteins and protein conjugates with increased hydrophobicity
CN116077648A (zh) 2015-12-11 2023-05-09 武田药品工业株式会社 血浆激肽释放酶抑制剂及其治疗遗传性血管性水肿发作的用途
MX2022008649A (es) 2020-01-13 2022-09-23 Takeda Pharmaceuticals Co Inhibidores de calicreina plasmatica y sus usos para tratar episodios de angioedema hereditario pediatrico.

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US153694A (en) * 1874-08-04 Improvement in clothes-pounders
KR850004274A (ko) 1983-12-13 1985-07-11 원본미기재 에리트로포이에틴의 제조방법
US5252714A (en) 1990-11-28 1993-10-12 The University Of Alabama In Huntsville Preparation and use of polyethylene glycol propionaldehyde
US5464933A (en) * 1993-06-07 1995-11-07 Duke University Synthetic peptide inhibitors of HIV transmission
US5795569A (en) * 1994-03-31 1998-08-18 Amgen Inc. Mono-pegylated proteins that stimulate megakaryocyte growth and differentiation
CH690143A5 (de) 1995-01-27 2000-05-15 Rieter Automotive Int Ag Lambda/4-Schallabsorber.
US5672662A (en) 1995-07-07 1997-09-30 Shearwater Polymers, Inc. Poly(ethylene glycol) and related polymers monosubstituted with propionic or butanoic acids and functional derivatives thereof for biotechnical applications
US5990237A (en) 1997-05-21 1999-11-23 Shearwater Polymers, Inc. Poly(ethylene glycol) aldehyde hydrates and related polymers and applications in modifying amines
ES2245505T3 (es) * 1998-03-23 2006-01-01 Trimeris Inc. Metodos y composiciones para la sintesis de peptidos (t-20).
US6281331B1 (en) 1998-03-23 2001-08-28 Trimeris, Inc. Methods and compositions for peptide synthesis
WO2000024697A1 (en) 1998-10-26 2000-05-04 University Of Utah Research Foundation Method for preparation of polyethylene glycol aldehyde derivatives
AU2346900A (en) * 1998-11-30 2000-06-19 Eli Lilly And Company Erythropoietic compounds
JO2291B1 (en) 1999-07-02 2005-09-12 اف . هوفمان لاروش ايه جي Erythropoietin derivatives
RU2179980C2 (ru) * 2000-03-20 2002-02-27 Государственный научный центр вирусологии и биотехнологии "Вектор" Пептид-имитатор консервативного эпитопа белка gp41 вируса иммунодефицита человека типа 1, узнаваемого вируснейтрализующими моноклональными антителами 2f5 (варианты)
KR100488351B1 (ko) 2001-12-11 2005-05-11 선바이오(주) 신규한 폴리에틸렌글리콜-프로피온알데히드 유도체

Also Published As

Publication number Publication date
JP2006511455A (ja) 2006-04-06
AU2003257467A1 (en) 2004-02-23
IL166038A0 (en) 2006-01-15
TW200416225A (en) 2004-09-01
AU2003257467B2 (en) 2008-02-28
KR100637981B1 (ko) 2006-10-23
US7049415B2 (en) 2006-05-23
CN1671736A (zh) 2005-09-21
CA2493534C (en) 2010-01-26
HRP20050024A2 (en) 2006-02-28
NO20050066L (no) 2005-04-22
KR20050027257A (ko) 2005-03-18
DE60335111D1 (de) 2011-01-05
BR0312889A (pt) 2005-06-14
CA2493534A1 (en) 2004-02-12
AR040651A1 (es) 2005-04-13
IL166038A (en) 2010-11-30
PE20040705A1 (es) 2004-10-14
EP1527088B1 (de) 2010-11-24
RU2005105577A (ru) 2005-10-27
US20040049018A1 (en) 2004-03-11
WO2004013164A1 (en) 2004-02-12
GT200300155A (es) 2004-03-15
PA8577701A1 (es) 2004-02-07
PL375254A1 (en) 2005-11-28
CN100357317C (zh) 2007-12-26
JP4381301B2 (ja) 2009-12-09
MXPA05000797A (es) 2005-04-19
ES2354609T3 (es) 2011-03-16
ZA200500258B (en) 2006-01-25
EP1527088A1 (de) 2005-05-04
RU2296769C2 (ru) 2007-04-10

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