ATE489471T1 - Verwendung von dimethyldisulfid für die methioninproduktion in mikroorganismen - Google Patents
Verwendung von dimethyldisulfid für die methioninproduktion in mikroorganismenInfo
- Publication number
- ATE489471T1 ATE489471T1 AT06800107T AT06800107T ATE489471T1 AT E489471 T1 ATE489471 T1 AT E489471T1 AT 06800107 T AT06800107 T AT 06800107T AT 06800107 T AT06800107 T AT 06800107T AT E489471 T1 ATE489471 T1 AT E489471T1
- Authority
- AT
- Austria
- Prior art keywords
- source
- methionine
- dmds
- methyl
- dimethyl disulfide
- Prior art date
Links
- WQOXQRCZOLPYPM-UHFFFAOYSA-N dimethyl disulfide Chemical compound CSSC WQOXQRCZOLPYPM-UHFFFAOYSA-N 0.000 title abstract 12
- FFEARJCKVFRZRR-BYPYZUCNSA-N L-methionine Chemical compound CSCC[C@H](N)C(O)=O FFEARJCKVFRZRR-BYPYZUCNSA-N 0.000 title abstract 5
- 229930182817 methionine Natural products 0.000 title abstract 5
- 238000004519 manufacturing process Methods 0.000 title abstract 3
- 244000005700 microbiome Species 0.000 title 1
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 6
- UCKMPCXJQFINFW-UHFFFAOYSA-N Sulphide Chemical compound [S-2] UCKMPCXJQFINFW-UHFFFAOYSA-N 0.000 abstract 5
- 241000186226 Corynebacterium glutamicum Species 0.000 abstract 2
- 102000004190 Enzymes Human genes 0.000 abstract 1
- 108090000790 Enzymes Proteins 0.000 abstract 1
- 241000588724 Escherichia coli Species 0.000 abstract 1
- FCXZBWSIAGGPCB-YFKPBYRVSA-N O-acetyl-L-homoserine Chemical compound CC(=O)OCC[C@H]([NH3+])C([O-])=O FCXZBWSIAGGPCB-YFKPBYRVSA-N 0.000 abstract 1
- QAOWNCQODCNURD-UHFFFAOYSA-L Sulfate Chemical compound [O-]S([O-])(=O)=O QAOWNCQODCNURD-UHFFFAOYSA-L 0.000 abstract 1
- NINIDFKCEFEMDL-UHFFFAOYSA-N Sulfur Chemical compound [S] NINIDFKCEFEMDL-UHFFFAOYSA-N 0.000 abstract 1
- 230000015572 biosynthetic process Effects 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- MYWUZJCMWCOHBA-VIFPVBQESA-N methamphetamine Chemical compound CN[C@@H](C)CC1=CC=CC=C1 MYWUZJCMWCOHBA-VIFPVBQESA-N 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 229910052717 sulfur Inorganic materials 0.000 abstract 1
- 239000011593 sulfur Substances 0.000 abstract 1
- 238000003786 synthesis reaction Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P13/00—Preparation of nitrogen-containing organic compounds
- C12P13/04—Alpha- or beta- amino acids
- C12P13/12—Methionine; Cysteine; Cystine
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Wood Science & Technology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Microbiology (AREA)
- General Chemical & Material Sciences (AREA)
- Biotechnology (AREA)
- Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Enzymes And Modification Thereof (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US70069805P | 2005-07-18 | 2005-07-18 | |
| US71390705P | 2005-09-01 | 2005-09-01 | |
| PCT/US2006/027855 WO2007011939A2 (en) | 2005-07-18 | 2006-07-18 | Use of dimethyl disulfide for methionine production in microorganisms |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE489471T1 true ATE489471T1 (de) | 2010-12-15 |
Family
ID=37669511
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT06800107T ATE489471T1 (de) | 2005-07-18 | 2006-07-18 | Verwendung von dimethyldisulfid für die methioninproduktion in mikroorganismen |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US8399214B2 (de) |
| EP (1) | EP1907558B1 (de) |
| JP (1) | JP2009501548A (de) |
| KR (1) | KR20080033413A (de) |
| AT (1) | ATE489471T1 (de) |
| BR (1) | BRPI0612900A8 (de) |
| CA (1) | CA2615315C (de) |
| DE (1) | DE602006018468D1 (de) |
| RU (1) | RU2413001C2 (de) |
| WO (1) | WO2007011939A2 (de) |
Families Citing this family (28)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE102004013503A1 (de) | 2004-03-18 | 2005-10-06 | Degussa Ag | Verfahren zur Herstellung von L-Aminosäuren unter Verwendung coryneformer Bakterien |
| ES2575082T3 (es) | 2007-04-11 | 2016-06-24 | Cj Cheiljedang Corporation | Composiciones y métodos de producción de metionina |
| US20090275112A1 (en) * | 2008-04-30 | 2009-11-05 | Bio-Reaction Industries, Llc | Nutrient additives for start-up and sustained operation of a biological filter apparatus |
| WO2010020290A1 (en) * | 2008-08-22 | 2010-02-25 | Metabolic Explorer | Producing methionine without n-acetyl methionine |
| KR101048593B1 (ko) * | 2009-02-27 | 2011-07-12 | 씨제이제일제당 (주) | 메칠머캅탄과 디메칠설파이드의 혼합물을 사용하여 메치오닌 생산능을 증가시키는 방법 |
| DE102009030342A1 (de) | 2009-06-25 | 2010-12-30 | Evonik Degussa Gmbh | Verfahren zur fermentativen Herstellung von organisch chemischen Verbindungen |
| JP5960604B2 (ja) | 2009-12-17 | 2016-08-02 | ビーエーエスエフ ソシエタス・ヨーロピアＢａｓｆ Ｓｅ | カダベリンの生産のための方法及び組換え微生物 |
| WO2011080542A1 (en) * | 2009-12-30 | 2011-07-07 | Metabolic Explorer | Increasing methionine production by overexpressing succinate dehydrogenase |
| KR101250651B1 (ko) * | 2010-12-21 | 2013-04-03 | 씨제이제일제당 (주) | 신규 ｏ-아세틸호모세린 설피드릴라제 또는 변이체 및 이를 이용한 메치오닌 전환 방법 |
| EP2479279A1 (de) | 2011-01-20 | 2012-07-25 | Evonik Degussa GmbH | Verfahren zur fermentativen Herstellung schwefelhaltiger Aminosäuren |
| CN103492553B (zh) | 2011-02-22 | 2018-06-12 | 巴斯夫欧洲公司 | 用于生产尸胺的方法和重组微生物 |
| DE102011006716A1 (de) | 2011-04-04 | 2012-10-04 | Evonik Degussa Gmbh | Mikroorganismus und Verfahren zur fermentativen Herstellung einer organisch-chemischen Verbindung |
| DE102011118019A1 (de) | 2011-06-28 | 2013-01-03 | Evonik Degussa Gmbh | Varianten des Promotors des für die Glyzerinaldehyd-3-phosphat-Dehydrogenase kodierenden gap-Gens |
| EP2762571A1 (de) | 2013-01-30 | 2014-08-06 | Evonik Industries AG | Mikroorganismus und Verfahren zur fermentativen Herstellung von Aminosäuren |
| WO2015028674A1 (en) | 2013-08-30 | 2015-03-05 | Metabolic Explorer | Microorganism for methionine production with improved methionine synthase activity and methionine efflux |
| KR101555750B1 (ko) * | 2013-10-23 | 2015-09-25 | 씨제이제일제당 (주) | O-숙시닐호모세린 생산 미생물 및 이를 이용한 o-숙시닐호모세린의 생산방법 |
| KR101555749B1 (ko) * | 2013-10-23 | 2015-09-25 | 씨제이제일제당 (주) | O-숙시닐호모세린 생산 미생물 및 이를 이용한 o-숙시닐호모세린의 생산방법 |
| EP3094718A4 (de) * | 2014-01-16 | 2017-06-07 | Calysta, Inc. | Mikroorganismen für die erhöhte produktion von aminosäuren und zugehörige verfahren |
| RU2723714C2 (ru) | 2014-09-01 | 2020-06-17 | Эвоник Оперейшнс Гмбх | Способ и микроорганизм для ферментативного продуцирования метионина с улучшенным выходом метионина |
| FR3041659B1 (fr) * | 2015-09-30 | 2017-10-20 | Arkema France | Procede de production de l-methionine |
| FR3041658B1 (fr) * | 2015-09-30 | 2017-10-20 | Arkema France | Procede de production de l-methionine |
| CN108291243A (zh) * | 2015-11-27 | 2018-07-17 | 赢创德固赛有限公司 | 生产l-甲硫氨酸的方法 |
| EP3296404A1 (de) | 2016-09-15 | 2018-03-21 | Evonik Degussa GmbH | Modifizierter mikroorganismus zur herstellung von methionin |
| JP7188385B2 (ja) * | 2016-10-26 | 2022-12-13 | 味の素株式会社 | Ｌ－メチオニンまたは合成にｓ－アデノシルメチオニンを要求する代謝物の製造方法 |
| EP3354742A1 (de) | 2017-01-26 | 2018-08-01 | Metabolic Explorer | Verfahren und mikroorganismen zur herstellung von glycolsäure und/oder glyoxylsäure |
| KR20250133497A (ko) | 2024-02-28 | 2025-09-08 | 경북대학교 산학협력단 | L-메티오닌 생산능이 향상된 재조합 미생물 및 이를 이용한 l-메티오닌 생산 방법 |
| CN119082224B (zh) * | 2024-09-26 | 2025-12-12 | 杭州精构生物科技有限责任公司 | 一种生产o-乙酰高丝氨酸的大肠埃希氏菌工程菌株的发酵方法 |
| CN120192894A (zh) * | 2025-04-10 | 2025-06-24 | 泸州品创科技有限公司 | 产二甲基三硫的解淀粉芽孢杆菌及其分离培养方法和应用 |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3962429A (en) * | 1973-08-01 | 1976-06-08 | Chugai Seiyaku Kabushiki Kaisha | Method for reducing side effects of aminoglycoside antibiotics and composition therefor |
| JPH07503855A (ja) * | 1992-02-20 | 1995-04-27 | ジェネンコア インターナショナル インコーポレーテッド | 硫黄の還元源を用いたメチオニンの生合成 |
| JP4088982B2 (ja) * | 1996-10-15 | 2008-05-21 | 味の素株式会社 | 発酵法によるｌ−アミノ酸の製造法 |
| RU2209248C2 (ru) * | 2001-06-26 | 2003-07-27 | Закрытое акционерное общество "Научно-исследовательский институт Аджиномото-Генетика" | Способ получения l-метионина, штамм бактерии escherichia coli вкпм в-8125 - продуцент l-метионина |
| DE10222858A1 (de) * | 2002-05-23 | 2003-12-04 | Basf Ag | Verfahren zur fermentativen Herstellung schwefelhaltiger Feinchemikalien |
| DE10239082A1 (de) * | 2002-08-26 | 2004-03-04 | Basf Ag | Verfahren zur fermentativen Herstellung schwefelhaltiger Feinchemikalien |
| DE10239073A1 (de) * | 2002-08-26 | 2004-03-11 | Basf Ag | Verfahren zur fermentativen Herstellung schwefelhaltiger Feinchemikalien |
| DE10239308A1 (de) * | 2002-08-27 | 2004-03-11 | Basf Ag | Verfahren zur fermentativen Herstellung von schwefelhaltigen Feinchemikalien |
| BRPI0407600A (pt) * | 2003-02-18 | 2006-02-14 | Metabolic Explorer Sa | processos de preparação de microorganismos evoluìdos e de uma proteìna evoluìda e de biotransformação, gene evoluìdo, proteìna evoluìda, e utilização de um microorganismo evoluìdo ou de uma proteìna evoluìda |
| KR20060018868A (ko) * | 2003-05-30 | 2006-03-02 | 마이크로비아 인코포레이티드 | 아미노산 생산 방법 및 아미노산 생산용 조성물 |
-
2006
- 2006-07-18 AT AT06800107T patent/ATE489471T1/de not_active IP Right Cessation
- 2006-07-18 EP EP06800107A patent/EP1907558B1/de active Active
- 2006-07-18 US US11/988,971 patent/US8399214B2/en not_active Expired - Fee Related
- 2006-07-18 JP JP2008522894A patent/JP2009501548A/ja active Pending
- 2006-07-18 WO PCT/US2006/027855 patent/WO2007011939A2/en not_active Ceased
- 2006-07-18 KR KR1020087003738A patent/KR20080033413A/ko not_active Ceased
- 2006-07-18 RU RU2008138584/10A patent/RU2413001C2/ru active
- 2006-07-18 CA CA2615315A patent/CA2615315C/en not_active Expired - Fee Related
- 2006-07-18 DE DE602006018468T patent/DE602006018468D1/de active Active
- 2006-07-18 BR BRPI0612900A patent/BRPI0612900A8/pt not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| BRPI0612900A2 (pt) | 2014-10-14 |
| CA2615315A1 (en) | 2007-01-25 |
| EP1907558B1 (de) | 2010-11-24 |
| US8399214B2 (en) | 2013-03-19 |
| RU2413001C2 (ru) | 2011-02-27 |
| KR20080033413A (ko) | 2008-04-16 |
| WO2007011939A3 (en) | 2007-07-05 |
| BRPI0612900A8 (pt) | 2022-07-19 |
| WO2007011939A2 (en) | 2007-01-25 |
| CA2615315C (en) | 2015-10-06 |
| DE602006018468D1 (de) | 2011-01-05 |
| JP2009501548A (ja) | 2009-01-22 |
| US20090281353A1 (en) | 2009-11-12 |
| RU2008138584A (ru) | 2010-04-10 |
| EP1907558A2 (de) | 2008-04-09 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |