ATE490309T1 - Mutante e. coli-appa-phytaseenzyme und natürliche varianten davon, solche phytaseenzyme codierende nukleinsäuren, diese enthaltende vektoren und wirtszellen und verfahren zur herstellung und verwendung davon - Google Patents
Mutante e. coli-appa-phytaseenzyme und natürliche varianten davon, solche phytaseenzyme codierende nukleinsäuren, diese enthaltende vektoren und wirtszellen und verfahren zur herstellung und verwendung davonInfo
- Publication number
- ATE490309T1 ATE490309T1 AT03785159T AT03785159T ATE490309T1 AT E490309 T1 ATE490309 T1 AT E490309T1 AT 03785159 T AT03785159 T AT 03785159T AT 03785159 T AT03785159 T AT 03785159T AT E490309 T1 ATE490309 T1 AT E490309T1
- Authority
- AT
- Austria
- Prior art keywords
- zymes
- phytase
- methods
- mutant
- coli
- Prior art date
Links
- 108010011619 6-Phytase Proteins 0.000 title abstract 6
- 229940085127 phytase Drugs 0.000 title 2
- 150000007523 nucleic acids Chemical class 0.000 title 1
- 102000039446 nucleic acids Human genes 0.000 title 1
- 108020004707 nucleic acids Proteins 0.000 title 1
- 239000013598 vector Substances 0.000 title 1
- 239000013589 supplement Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
- C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
- C12N15/8242—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits
- C12N15/8243—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits involving biosynthetic or metabolic pathways, i.e. metabolic engineering, e.g. nicotine, caffeine
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
- C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
- C12N15/8242—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits
- C12N15/8243—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits involving biosynthetic or metabolic pathways, i.e. metabolic engineering, e.g. nicotine, caffeine
- C12N15/8245—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits involving biosynthetic or metabolic pathways, i.e. metabolic engineering, e.g. nicotine, caffeine involving modified carbohydrate or sugar alcohol metabolism, e.g. starch biosynthesis
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/16—Hydrolases (3) acting on ester bonds (3.1)
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Genetics & Genomics (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Biotechnology (AREA)
- Organic Chemistry (AREA)
- Molecular Biology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Biomedical Technology (AREA)
- General Engineering & Computer Science (AREA)
- Nutrition Science (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- Cell Biology (AREA)
- Plant Pathology (AREA)
- Biophysics (AREA)
- Physics & Mathematics (AREA)
- Medicinal Chemistry (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Enzymes And Modification Thereof (AREA)
- Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US40333002P | 2002-08-12 | 2002-08-12 | |
| PCT/US2003/025058 WO2004015084A2 (en) | 2002-08-12 | 2003-08-11 | Mutant e. coli appa phytase enzymes |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE490309T1 true ATE490309T1 (de) | 2010-12-15 |
Family
ID=31715975
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT03785159T ATE490309T1 (de) | 2002-08-12 | 2003-08-11 | Mutante e. coli-appa-phytaseenzyme und natürliche varianten davon, solche phytaseenzyme codierende nukleinsäuren, diese enthaltende vektoren und wirtszellen und verfahren zur herstellung und verwendung davon |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US7968342B2 (de) |
| EP (1) | EP1546316B1 (de) |
| CN (2) | CN101792749B (de) |
| AT (1) | ATE490309T1 (de) |
| AU (1) | AU2003258157A1 (de) |
| CA (1) | CA2495660A1 (de) |
| DE (1) | DE60335195D1 (de) |
| DK (1) | DK1546316T3 (de) |
| WO (1) | WO2004015084A2 (de) |
Families Citing this family (36)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8114443B2 (en) * | 2002-03-13 | 2012-02-14 | Academia Sinica | Phytase-expressing transgenic plants |
| CN101792749B (zh) * | 2002-08-12 | 2012-09-05 | 金克克国际有限公司 | 大肠杆菌AppA肌醇六磷酸酶突变体 |
| DE102004050410A1 (de) | 2004-10-15 | 2006-06-08 | Ab Enzymes Gmbh | Polypeptid mit Phytaseaktivität und dieses codierende Nucleotidsequenz |
| GB0423139D0 (en) * | 2004-10-18 | 2004-11-17 | Danisco | Enzymes |
| US20060194299A1 (en) * | 2005-02-04 | 2006-08-31 | Henrik Brinch-Pedersen | Method for recycling important nutritional elements from waste |
| CN101460612B (zh) * | 2006-04-04 | 2015-05-06 | 诺维信公司 | 肌醇六磷酸酶变体 |
| DK2365064T3 (en) * | 2006-04-04 | 2015-03-30 | Novozymes As | Phytasevarianter |
| ES2288126B2 (es) * | 2006-06-01 | 2009-07-06 | Universitat De Les Illes Balears | Utilizacion de fitato como agente inhibidor de la disolucion de cristales de sales calcicas para la prevencion o tratamiento de la osteoporosis. |
| EP2049669A2 (de) * | 2006-08-09 | 2009-04-22 | DSMIP Assets B.V. | Sporenoberflächenanzeigen bioaktiver moleküle |
| JP5307013B2 (ja) | 2006-09-21 | 2013-10-02 | ヴェレニウム コーポレイション | フィターゼ、フィターゼをコードする核酸、並びにフィターゼを製造および使用する方法 |
| DE102006053059A1 (de) | 2006-11-10 | 2008-05-15 | Ab Enzymes Gmbh | Polypeptid mit Phytaseaktivität und erhöhter Temperaturstabilität der Enzymaktivität sowie dieses codierende Nukleotidsequenz |
| US8143046B2 (en) | 2007-02-07 | 2012-03-27 | Danisco Us Inc., Genencor Division | Variant Buttiauxella sp. phytases having altered properties |
| DK2011858T3 (da) * | 2007-07-06 | 2012-08-06 | Chr Hansen As | Et galderesistent bacillus-præparat med høje niveauer af fytase-udskillelse |
| EP2283124B1 (de) * | 2008-04-18 | 2016-05-25 | Danisco US Inc. | Buttiauxella sp.-phytase-varianten |
| RU2011129817A (ru) | 2008-12-19 | 2013-01-27 | Кр.Хансен А/С | Композиция палочковидных бактерий, устойчивых к желчи |
| CN101492688B (zh) * | 2009-01-08 | 2010-12-08 | 西南大学 | 枯草芽孢杆菌中性植酸酶phyC基因 |
| GB0922467D0 (en) * | 2009-04-24 | 2010-02-03 | Danisco | Feed supplement |
| WO2010135588A2 (en) | 2009-05-21 | 2010-11-25 | Verenium Corporation | Phytases, nucleic acids encoding them and methods for making and using them |
| EP2478359A4 (de) * | 2009-09-14 | 2013-03-20 | Univ Rockefeller | Verfahren zur identifikation entzündungshemmender verbindungen |
| DK2491120T3 (en) * | 2009-10-22 | 2016-03-21 | Basf Se | Synthetic phytasevarianter |
| CN106399273B (zh) * | 2013-07-24 | 2019-09-20 | 东莞泛亚太生物科技有限公司 | 具有提升的酶活性的植酸酶 |
| TWI478936B (zh) * | 2013-07-24 | 2015-04-01 | Genozyme Biotech Inc | 具提升酶活性之植酸酶 |
| WO2015070372A1 (zh) * | 2013-11-12 | 2015-05-21 | 中国农业科学院饲料研究所 | 一种产生热稳定性改良的植酸酶变体的方法、以及植酸酶变体及其应用 |
| ES2759083T3 (es) | 2014-11-21 | 2020-05-07 | Qingdao Vland Biotech Group Co Ltd | Mutantes de fitasa |
| WO2017152169A1 (en) | 2016-03-04 | 2017-09-08 | Danisco Us Inc. | Engineered ribosomal promoters for protein production in microorganisms |
| CA3017137A1 (en) | 2016-03-08 | 2017-09-14 | Basf Enzymes Llc | Methods for using phytase in ethanol production |
| US9528096B1 (en) * | 2016-06-30 | 2016-12-27 | Fornia Biosolutions, Inc. | Phytases and uses thereof |
| US10351832B2 (en) | 2016-06-30 | 2019-07-16 | Fornia Biosolutions, Inc. | Phytases and uses thereof |
| US9605245B1 (en) | 2016-06-30 | 2017-03-28 | Fornia BioSoultions, Inc. | Phytases and uses thereof |
| EP3703661A1 (de) | 2017-11-02 | 2020-09-09 | Danisco US Inc. | Feste matrixzusammensetzungen mit gesenktem gefrierpunkt für die schmelzgranulation von enzymen |
| CN108251439B (zh) * | 2018-01-11 | 2021-03-30 | 山西大学 | 一种人工改造的耐胰蛋白酶的植酸酶及其制备方法和应用 |
| US20200359656A1 (en) | 2018-02-08 | 2020-11-19 | Danisco Us Inc. | Thermally-resistant wax matrix particles for enzyme encapsulation |
| CA3098454A1 (en) | 2018-04-26 | 2019-10-31 | Danisco Us Inc | Method for increasing stability of phytase in a solid composition and a granule composition comprising phosphate and phytase |
| AU2018445164B2 (en) | 2018-10-11 | 2025-05-29 | Vifor (International) Ltd. | Inositol phosphates for the treatment of ectopic calcification |
| CN110484455B (zh) * | 2019-06-10 | 2022-05-24 | 潍坊康地恩生物科技有限公司 | 一种稳定高产植酸酶的木霉突变菌株 |
| CN111826323A (zh) * | 2020-08-05 | 2020-10-27 | 福建洛东生物技术有限公司 | 一种枯草芽孢杆菌及其制剂与应用 |
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| US4179337A (en) | 1973-07-20 | 1979-12-18 | Davis Frank F | Non-immunogenic polypeptides |
| JPS6023084B2 (ja) | 1979-07-11 | 1985-06-05 | 味の素株式会社 | 代用血液 |
| US4640835A (en) | 1981-10-30 | 1987-02-03 | Nippon Chemiphar Company, Ltd. | Plasminogen activator derivatives |
| US4496689A (en) | 1983-12-27 | 1985-01-29 | Miles Laboratories, Inc. | Covalently attached complex of alpha-1-proteinase inhibitor with a water soluble polymer |
| US5034506A (en) | 1985-03-15 | 1991-07-23 | Anti-Gene Development Group | Uncharged morpholino-based polymers having achiral intersubunit linkages |
| US5235033A (en) | 1985-03-15 | 1993-08-10 | Anti-Gene Development Group | Alpha-morpholino ribonucleoside derivatives and polymers thereof |
| DE3675588D1 (de) | 1985-06-19 | 1990-12-20 | Ajinomoto Kk | Haemoglobin, das an ein poly(alkenylenoxid) gebunden ist. |
| AU597574B2 (en) | 1986-03-07 | 1990-06-07 | Massachusetts Institute Of Technology | Method for enhancing glycoprotein stability |
| US5750871A (en) | 1986-05-29 | 1998-05-12 | Calgene, Inc. | Transformation and foreign gene expression in Brassica species |
| US4791192A (en) | 1986-06-26 | 1988-12-13 | Takeda Chemical Industries, Ltd. | Chemically modified protein with polyethyleneglycol |
| US5633076A (en) | 1989-12-01 | 1997-05-27 | Pharming Bv | Method of producing a transgenic bovine or transgenic bovine embryo |
| FR2673643B1 (fr) | 1991-03-05 | 1993-05-21 | Rhone Poulenc Agrochimie | Peptide de transit pour l'insertion d'un gene etranger dans un gene vegetal et plantes transformees en utilisant ce peptide. |
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| US5571706A (en) | 1994-06-17 | 1996-11-05 | The United States Of America As Represented By The Secretary Of Agriculture | Plant virus resistance gene and methods |
| AU2077197A (en) | 1996-03-18 | 1997-10-10 | Novo Nordisk Biotech, Inc. | Polypeptides having phytase activity and nucleic acids encoding same |
| EP0955362A4 (de) | 1996-04-05 | 2002-08-14 | Kyowa Hakko Kogyo Kk | Neuartige phytase und für diese kodierendes gen |
| US5773269A (en) | 1996-07-26 | 1998-06-30 | Regents Of The University Of Minnesota | Fertile transgenic oat plants |
| KR20000036143A (ko) | 1996-09-25 | 2000-06-26 | 히라다 다다시 | 신규피틴산 분해효소 및 그의 제조방법 |
| US6039942A (en) | 1996-12-20 | 2000-03-21 | Novo Nordick A/S | Phytase polypeptides |
| US5876997A (en) | 1997-08-13 | 1999-03-02 | Diversa Corporation | Phytase |
| US6183740B1 (en) * | 1997-08-13 | 2001-02-06 | Diversa Corporation | Recombinant bacterial phytases and uses thereof |
| US6720014B1 (en) * | 1997-08-13 | 2004-04-13 | Diversa Corporation | Phytase-containing foodstuffs and methods of making and using them |
| US6855365B2 (en) * | 1997-08-13 | 2005-02-15 | Diversa Corporation | Recombinant bacterial phytases and uses thereof |
| GB9917975D0 (en) | 1999-07-30 | 1999-09-29 | Smithkline Beecham Biolog | Novel compounds |
| PL354805A1 (en) | 1999-11-18 | 2004-02-23 | Cornell Research Foundation, Inc. | Site-directed mutagenesis of escherichia coli |
| WO2002048332A2 (en) | 2000-12-12 | 2002-06-20 | Diversa Corporation | Recombinant phytases and uses thereof |
| CN101792749B (zh) * | 2002-08-12 | 2012-09-05 | 金克克国际有限公司 | 大肠杆菌AppA肌醇六磷酸酶突变体 |
-
2003
- 2003-08-11 CN CN2010101238485A patent/CN101792749B/zh not_active Expired - Fee Related
- 2003-08-11 CA CA002495660A patent/CA2495660A1/en not_active Abandoned
- 2003-08-11 WO PCT/US2003/025058 patent/WO2004015084A2/en not_active Ceased
- 2003-08-11 CN CN03824125A patent/CN100594239C/zh not_active Expired - Fee Related
- 2003-08-11 AT AT03785159T patent/ATE490309T1/de not_active IP Right Cessation
- 2003-08-11 AU AU2003258157A patent/AU2003258157A1/en not_active Abandoned
- 2003-08-11 EP EP03785159A patent/EP1546316B1/de not_active Expired - Lifetime
- 2003-08-11 DK DK03785159.9T patent/DK1546316T3/da active
- 2003-08-11 DE DE60335195T patent/DE60335195D1/de not_active Expired - Lifetime
- 2003-08-11 US US10/524,234 patent/US7968342B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| AU2003258157A1 (en) | 2004-02-25 |
| US7968342B2 (en) | 2011-06-28 |
| WO2004015084A3 (en) | 2004-10-28 |
| CN101792749B (zh) | 2012-09-05 |
| US20060141562A1 (en) | 2006-06-29 |
| CA2495660A1 (en) | 2004-02-19 |
| CN100594239C (zh) | 2010-03-17 |
| DK1546316T3 (da) | 2011-02-14 |
| DE60335195D1 (de) | 2011-01-13 |
| WO2004015084A2 (en) | 2004-02-19 |
| EP1546316A2 (de) | 2005-06-29 |
| AU2003258157A8 (en) | 2004-02-25 |
| EP1546316A4 (de) | 2007-05-02 |
| EP1546316B1 (de) | 2010-12-01 |
| CN101792749A (zh) | 2010-08-04 |
| CN1688690A (zh) | 2005-10-26 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |