ATE162853T1 - Menschlicher rekombinanter plazentaler ribonuklease-inhibitor und verfahren zur herstellung - Google Patents

Menschlicher rekombinanter plazentaler ribonuklease-inhibitor und verfahren zur herstellung

Info

Publication number
ATE162853T1
ATE162853T1 AT90908084T AT90908084T ATE162853T1 AT E162853 T1 ATE162853 T1 AT E162853T1 AT 90908084 T AT90908084 T AT 90908084T AT 90908084 T AT90908084 T AT 90908084T AT E162853 T1 ATE162853 T1 AT E162853T1
Authority
AT
Austria
Prior art keywords
ribonuclease inhibitor
placental ribonuclease
human placental
producing
human recombinant
Prior art date
Application number
AT90908084T
Other languages
English (en)
Inventor
Martin Kendall Lewis
John William Shultz
Original Assignee
Promega Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Promega Corp filed Critical Promega Corp
Application granted granted Critical
Publication of ATE162853T1 publication Critical patent/ATE162853T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4702—Regulators; Modulating activity
    • C07K14/4703—Inhibitors; Suppressors
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/70—Vectors or expression systems specially adapted for E. coli
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
    • C07K2319/035—Fusion polypeptide containing a localisation/targetting motif containing a signal for targeting to the external surface of a cell, e.g. to the outer membrane of Gram negative bacteria, GPI- anchored eukaryote proteins

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Medicinal Chemistry (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Cardiology (AREA)
  • Toxicology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
AT90908084T 1989-04-24 1990-04-18 Menschlicher rekombinanter plazentaler ribonuklease-inhibitor und verfahren zur herstellung ATE162853T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US34236289A 1989-04-24 1989-04-24

Publications (1)

Publication Number Publication Date
ATE162853T1 true ATE162853T1 (de) 1998-02-15

Family

ID=23341508

Family Applications (1)

Application Number Title Priority Date Filing Date
AT90908084T ATE162853T1 (de) 1989-04-24 1990-04-18 Menschlicher rekombinanter plazentaler ribonuklease-inhibitor und verfahren zur herstellung

Country Status (8)

Country Link
EP (1) EP0422217B1 (de)
JP (2) JP3009458B2 (de)
AT (1) ATE162853T1 (de)
AU (1) AU646803B2 (de)
DE (1) DE69031996T2 (de)
DK (1) DK0422217T3 (de)
ES (1) ES2111537T3 (de)
WO (1) WO1990012881A1 (de)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0291686B1 (de) * 1987-04-14 1993-10-13 The President And Fellows Of Harvard College Angiogenininhibitoren
US7560248B1 (en) 1999-01-20 2009-07-14 Wisconsin Alumni Research Foundation Oxidation-resistant ribonuclease inhibitor
AU5927900A (en) * 1999-07-13 2001-01-30 Zymogenetics Inc. Alpha protein - 27
DE102005015005A1 (de) 2005-04-01 2006-10-05 Qiagen Gmbh Verfahren zur Behandlung einer Biomoleküle enthaltenden Probe
GB201101794D0 (en) * 2011-02-02 2011-03-16 Fermentas Uab Protein production
PL436077A1 (pl) * 2020-11-25 2022-05-30 Blirt Spółka Akcyjna Liofilizowany i gotowy do liofilizacji rekombinowany ludzki inhibitor RNaz

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0291686B1 (de) * 1987-04-14 1993-10-13 The President And Fellows Of Harvard College Angiogenininhibitoren

Also Published As

Publication number Publication date
EP0422217A1 (de) 1991-04-17
JP2000078992A (ja) 2000-03-21
EP0422217B1 (de) 1998-01-28
AU646803B2 (en) 1994-03-10
JP3009458B2 (ja) 2000-02-14
AU5537790A (en) 1990-11-16
DE69031996T2 (de) 1998-06-10
ES2111537T3 (es) 1998-03-16
WO1990012881A1 (en) 1990-11-01
DK0422217T3 (da) 1998-03-02
JPH03505677A (ja) 1991-12-12
EP0422217A4 (en) 1992-08-19
DE69031996D1 (de) 1998-03-05
JP3366596B2 (ja) 2003-01-14

Similar Documents

Publication Publication Date Title
NO179253C (no) Rekombinant DNA-sekvens som koder for humant proapolipoprotein A-I, ekspresjonsvektorer, cellekulturer samt fremgangsmåte for fremstilling av proteinet
HK49285A (en) Interferons and process for their preparation
DE69930955D1 (de) Polypeptide mit lysophospholipaseaktivität und nukleinesäuren die sie kodieren
EP0722461A4 (de) Expression eines fusionspolypeptides, das ohne leadersequenz aus dem cytoplasma transportiert wird
ES8306324A1 (es) "proceso para la produccion microbiana de interferon fibroblasto humano".
ATE352626T1 (de) Polypeptide mit galaktoseoxidaseaktivität und dafür kodierende nukleisäuren
DK224587A (da) Ekstracellulaer superoxiddismutase (ec-sod), dna-fragment, der indkoder ec-sod, fremgangsmaade til fremstilling af ec-sod samt anvendelse af ec-sod
DE69738483D1 (de) Polypeptide mit phytase-aktivität und sie kodierende nukleinsäuren
ATE5001T1 (de) Verfahren zur herstellung eines ausgewaehlten proteins.
ATE192500T1 (de) Rekombinante viren vektoren zur expression in muskelzellen
DE69839553D1 (de) Verfahren zur herstellung von proteinen
BR8301918A (pt) Proteina,sequencia de dna,veiculo de expressao replicavel,microorganismo ou cultura celular,plasmideo,composicao,cultura de celulas,utilizacao de tal proteina,processo de expressao,processo para producao de um veiculo de expressao e processo para preparacao de uma proteina uroquinase
ATE414775T1 (de) Polypeptide mit prolyldipeptidylaminopeptidase- aktivität und dafür kodierende nukleinsäuren
DE69329195D1 (de) Rekombinante dna moleküle die aminopeptidase enzyme kodieren und ihre anwendung für die herstellung von impfstoffen gegen helminth infektionen
PL1675956T3 (pl) Minimalna sekwencja DNA działająca jako insulator chromatyny i jej zastosowanie do wyrażania białek
DE69737413D1 (en) Bakterioferritin aus helicobacter pylori
DE69031996D1 (de) Menschlicher rekombinanter plazentaler ribonuklease-inhibitor und verfahren zur herstellung
ATE145004T1 (de) Verfahren zur herstellung von luciferase durch rekombinante expression eines luciferase- kodierenden gens
PT93614A (pt) Estirpe de levedura melhorada para a producao de proteinas heterologas maduras,em particular hirudina, e processo para a preparacao da hirudina correspondente
ATE43139T1 (de) Klonierungs- und expressionsvektoren fuer gammainterferon, transformierte bakterien und verfahren zur herstellung von gamma-interferon.
DE68920321D1 (de) Verfahren zur herstellung eines menschlichen "neutrophil chemotactic factor"-polypeptids.
ATE80181T1 (de) Zur wirksamen gen-expression faehiger vektor und verwendung desselben.

Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee