ATE490344T1 - Abcbi-genotypisierung zur vorhersage der mikrotubuli-stabilisatorwirkstoffinduzierten toxizität - Google Patents
Abcbi-genotypisierung zur vorhersage der mikrotubuli-stabilisatorwirkstoffinduzierten toxizitätInfo
- Publication number
- ATE490344T1 ATE490344T1 AT07799583T AT07799583T ATE490344T1 AT E490344 T1 ATE490344 T1 AT E490344T1 AT 07799583 T AT07799583 T AT 07799583T AT 07799583 T AT07799583 T AT 07799583T AT E490344 T1 ATE490344 T1 AT E490344T1
- Authority
- AT
- Austria
- Prior art keywords
- microtubule
- stabilizing agent
- abcb1
- induced toxicity
- subject
- Prior art date
Links
- 239000003381 stabilizer Substances 0.000 title abstract 5
- 230000001988 toxicity Effects 0.000 title abstract 2
- 231100000419 toxicity Toxicity 0.000 title abstract 2
- 239000003814 drug Substances 0.000 title 1
- 229940079593 drug Drugs 0.000 title 1
- 238000003205 genotyping method Methods 0.000 title 1
- 238000000034 method Methods 0.000 abstract 4
- 102100033350 ATP-dependent translocase ABCB1 Human genes 0.000 abstract 3
- 108010047230 Member 1 Subfamily B ATP Binding Cassette Transporter Proteins 0.000 abstract 3
- 230000002411 adverse Effects 0.000 abstract 2
- 230000000694 effects Effects 0.000 abstract 2
- 102000054765 polymorphisms of proteins Human genes 0.000 abstract 2
- 102000039446 nucleic acids Human genes 0.000 abstract 1
- 150000007523 nucleic acids Chemical class 0.000 abstract 1
- 108020004707 nucleic acids Proteins 0.000 abstract 1
- 238000002560 therapeutic procedure Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/106—Pharmacogenomics, i.e. genetic variability in individual responses to drugs and drug metabolism
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/156—Polymorphic or mutational markers
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/158—Expression markers
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/172—Haplotypes
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Organic Chemistry (AREA)
- Genetics & Genomics (AREA)
- Zoology (AREA)
- Analytical Chemistry (AREA)
- Wood Science & Technology (AREA)
- Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Physics & Mathematics (AREA)
- Pathology (AREA)
- Immunology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US80745306P | 2006-07-14 | 2006-07-14 | |
| PCT/US2007/073497 WO2008008976A1 (en) | 2006-07-14 | 2007-07-13 | Abcbi genotyping to predict microtubule-stabilizing-agent-induced toxicity |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE490344T1 true ATE490344T1 (de) | 2010-12-15 |
Family
ID=38691686
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT07799583T ATE490344T1 (de) | 2006-07-14 | 2007-07-13 | Abcbi-genotypisierung zur vorhersage der mikrotubuli-stabilisatorwirkstoffinduzierten toxizität |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US8835115B2 (de) |
| EP (1) | EP2041312B1 (de) |
| AT (1) | ATE490344T1 (de) |
| DE (1) | DE602007010939D1 (de) |
| ES (1) | ES2356789T3 (de) |
| WO (1) | WO2008008976A1 (de) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2009240232A (ja) * | 2008-03-31 | 2009-10-22 | Institute Of Physical & Chemical Research | 抗癌剤の副作用の危険性を検査する方法 |
| WO2023235415A1 (en) * | 2022-06-01 | 2023-12-07 | Genentech, Inc. | Method to identify a patient with an increased likelihood of chemotherapy-induced peripheral neuropathy |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6753177B1 (en) * | 1999-09-28 | 2004-06-22 | Becton Dickinson And Company | P-glycoproteins and uses thereof |
| EP1220917A1 (de) * | 1999-09-28 | 2002-07-10 | Gentest Corporation | P-glycoproteine aus macaca fascicularis und deren verwendungen |
| EP1337661A1 (de) * | 2000-11-29 | 2003-08-27 | Epidauros Biotechnologie AG | Verfahren zur diagnose von personen mit erhöhtem risiko, eine defizienz zu entwicklen aud der basis von mdr1 genpolymorphismus |
| DE60234440D1 (de) * | 2001-01-12 | 2009-12-31 | Univ Washington | Mdr1-varianten und verfahren zu ihrer verwendung |
| EP1421101A4 (de) * | 2001-03-19 | 2005-01-19 | Gentest Corp | P-glycoproteine und deren verwendungen |
| WO2004092399A2 (en) * | 2003-03-25 | 2004-10-28 | The University Of Tennessee Research Foundation | Real-time polmerase chain reaction-based genotyping assay for single nucleotide polymorphism |
| WO2005028645A1 (ja) | 2003-09-24 | 2005-03-31 | Kyushu Tlo Company, Limited | ＭＤＲ１遺伝子の５’制御領域におけるＳＮＰｓ |
| US7445897B2 (en) * | 2004-01-26 | 2008-11-04 | University Of Washington | Sequence variants of multi-drug resistance genes, MDR1 and MRP1, and methods for assessment of drug penetration and disposition |
| US8030033B2 (en) | 2004-05-12 | 2011-10-04 | Max-Planck-Gesellschaft Zur Forderung Der Wissenshaften E.V. | Polymorphisms in ABCB1 associated with a lack of clinical response to medicaments |
| US20090325156A1 (en) * | 2005-11-10 | 2009-12-31 | Government of the United States of America, as Represented by Secretary, Dept. of Human Services | Materials and methods for abcb1 polymorphic variant screening, diagnosis, and treatment |
-
2007
- 2007-07-13 ES ES07799583T patent/ES2356789T3/es active Active
- 2007-07-13 WO PCT/US2007/073497 patent/WO2008008976A1/en not_active Ceased
- 2007-07-13 EP EP07799583A patent/EP2041312B1/de not_active Not-in-force
- 2007-07-13 US US12/304,071 patent/US8835115B2/en active Active
- 2007-07-13 AT AT07799583T patent/ATE490344T1/de not_active IP Right Cessation
- 2007-07-13 DE DE602007010939T patent/DE602007010939D1/de active Active
Also Published As
| Publication number | Publication date |
|---|---|
| DE602007010939D1 (de) | 2011-01-13 |
| ES2356789T3 (es) | 2011-04-13 |
| EP2041312A1 (de) | 2009-04-01 |
| EP2041312B1 (de) | 2010-12-01 |
| US20100247481A1 (en) | 2010-09-30 |
| WO2008008976A1 (en) | 2008-01-17 |
| US8835115B2 (en) | 2014-09-16 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CA2735578C (en) | Method of identifying risk factors for alzheimer's disease comprising tomm40 gene variants | |
| MY150648A (en) | Hla alleles associated with adverse drug reactions and methods for detecting such | |
| Medina et al. | RHOA is a modulator of the cholesterol-lowering effects of statin | |
| WO2008137236A3 (en) | Treatment of age-related macular degeneration using inhibitors of complement factor d | |
| ATE496142T1 (de) | Verfahren zur diagnose von nicht-kleinzelligem lungenkrebs | |
| WO2009059317A3 (en) | Predicting amd with snps within or near c2, factor b, plekha1, htra1, prelp, or loc387715 | |
| ATE548467T1 (de) | Verfahren zur identifizierung von biomarkern mit eignung bei der diagnose biologischer zustände | |
| Kovacs‐Nagy et al. | Association of aggression with a novel microRNA binding site polymorphism in the wolframin gene | |
| MX343167B (es) | Metodos y composiciones para identificar y tratar lupus. | |
| WO2008132763A3 (en) | Genetic variants useful for risk assessment of coronary artery disease and myocardial infarction | |
| ATE504836T1 (de) | Verfahren zur identifizierung von trpv2- modulatoren | |
| WO2013056087A3 (en) | Compositions and methods for treating and preventing coronary heart disease | |
| WO2009149319A3 (en) | Gene expression profiles associated with asthma exacerbation attacks | |
| ZA200710910B (en) | Methods for the assessment of risk of developing lung cancer using analysis of genetic polymorphisms | |
| NO20090993L (no) | BIQ-markorer for vurdering av leverfunksjon | |
| WO2019204340A3 (en) | Biomarker for predicting equine gait and methods of use thereof | |
| ATE490344T1 (de) | Abcbi-genotypisierung zur vorhersage der mikrotubuli-stabilisatorwirkstoffinduzierten toxizität | |
| DK1730315T3 (da) | Polymorphismer i NOD2/Card15 gen | |
| WO2008018789A3 (en) | Methods and means for diagnosing and treatment of osteoarthritis | |
| ATE515576T1 (de) | Protein c polymorphismen | |
| Stickel et al. | No role of matrixmetalloproteinase‐3 genetic promoter polymorphism 1171 as a risk factor for cirrhosis in alcoholic liver disease | |
| WO2012068519A3 (en) | Markers associated with response to activated protein c administration, and uses thereof | |
| SE0402832D0 (sv) | Methods | |
| WO2008100244A3 (en) | Methods of detecting mutations associated with ataxia-ocular apraxia 2 (aoa2) | |
| ITRM20040357A1 (it) | Metodo per identificare agenti modulanti del metabolismo di molecole steroidee. |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |