ATE490772T1 - Tetrahydro-pyrroloä1,2-büisothiazol 1,1-dioxide als lfa-1 inhibitoren - Google Patents
Tetrahydro-pyrroloä1,2-büisothiazol 1,1-dioxide als lfa-1 inhibitorenInfo
- Publication number
- ATE490772T1 ATE490772T1 AT06819072T AT06819072T ATE490772T1 AT E490772 T1 ATE490772 T1 AT E490772T1 AT 06819072 T AT06819072 T AT 06819072T AT 06819072 T AT06819072 T AT 06819072T AT E490772 T1 ATE490772 T1 AT E490772T1
- Authority
- AT
- Austria
- Prior art keywords
- lfa
- tetrahydro
- dioxide
- pyrroloä1
- buisothiazole
- Prior art date
Links
- 102100022339 Integrin alpha-L Human genes 0.000 title abstract 2
- 108010064548 Lymphocyte Function-Associated Antigen-1 Proteins 0.000 title abstract 2
- 239000003112 inhibitor Substances 0.000 title 1
- NINIDFKCEFEMDL-UHFFFAOYSA-N Sulfur Chemical compound [S] NINIDFKCEFEMDL-UHFFFAOYSA-N 0.000 abstract 1
- 239000005864 Sulphur Substances 0.000 abstract 1
- 230000020411 cell activation Effects 0.000 abstract 1
- 230000021164 cell adhesion Effects 0.000 abstract 1
- 230000012292 cell migration Effects 0.000 abstract 1
- 230000003993 interaction Effects 0.000 abstract 1
- 239000003446 ligand Substances 0.000 abstract 1
- 230000001404 mediated effect Effects 0.000 abstract 1
- 238000013508 migration Methods 0.000 abstract 1
- 230000002265 prevention Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
- C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
- C07D513/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
- A61K31/429—Thiazoles condensed with heterocyclic ring systems
-
- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
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- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
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-
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- A—HUMAN NECESSITIES
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- A—HUMAN NECESSITIES
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- A61P5/00—Drugs for disorders of the endocrine system
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Immunology (AREA)
- Diabetes (AREA)
- Physical Education & Sports Medicine (AREA)
- Pulmonology (AREA)
- Endocrinology (AREA)
- Dermatology (AREA)
- Rheumatology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Hematology (AREA)
- Communicable Diseases (AREA)
- Epidemiology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Oncology (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Neurology (AREA)
- Pain & Pain Management (AREA)
- Biomedical Technology (AREA)
- Urology & Nephrology (AREA)
- Ophthalmology & Optometry (AREA)
- Obesity (AREA)
- Emergency Medicine (AREA)
- Virology (AREA)
- Gastroenterology & Hepatology (AREA)
- Transplantation (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB0520378.1A GB0520378D0 (en) | 2005-10-06 | 2005-10-06 | Organic compounds |
| PCT/EP2006/067017 WO2007039616A1 (en) | 2005-10-06 | 2006-10-04 | Pharmaceutically active tetrahydro-pyrrolo[1,2-b]isothiazole 1,1-dioxides |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE490772T1 true ATE490772T1 (de) | 2010-12-15 |
Family
ID=35429953
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT06819072T ATE490772T1 (de) | 2005-10-06 | 2006-10-04 | Tetrahydro-pyrroloä1,2-büisothiazol 1,1-dioxide als lfa-1 inhibitoren |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US20080242710A1 (de) |
| EP (1) | EP1933835B1 (de) |
| JP (1) | JP2009511448A (de) |
| KR (1) | KR20080046226A (de) |
| CN (1) | CN101282724A (de) |
| AT (1) | ATE490772T1 (de) |
| AU (1) | AU2006298658A1 (de) |
| BR (1) | BRPI0616880A2 (de) |
| CA (1) | CA2624493A1 (de) |
| DE (1) | DE602006018758D1 (de) |
| GB (1) | GB0520378D0 (de) |
| RU (1) | RU2008117330A (de) |
| WO (1) | WO2007039616A1 (de) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP5105578B2 (ja) | 2003-11-05 | 2012-12-26 | サーコード バイオサイエンス インコーポレイテッド | 細胞接着のモジュレーター |
| MX2010004281A (es) | 2007-10-19 | 2010-09-10 | Sarcode Corp | Composiciones y metodos para el tratamiento de la retinopatia diabetica. |
| HK1254289A1 (zh) | 2015-06-12 | 2019-07-19 | 台湾基督长老教会马偕医疗财团法人马偕纪念医院 | 调控免疫反应的方法及抗体 |
| EP3551034A1 (de) | 2016-12-07 | 2019-10-16 | Progenity, Inc. | Verfahren, vorrichtungen und systeme zur detektion des magen-darm-trakts |
| KR20190095936A (ko) | 2016-12-14 | 2019-08-16 | 프로제너티, 인크. | 인테그린 저해제로의 위장관 질환의 치료 |
| EP3810085A1 (de) | 2018-06-20 | 2021-04-28 | Progenity, Inc. | Behandlung der erkrankung des gastrointestinaltraktes mit einem integrin-inhibitor |
| WO2020106757A1 (en) | 2018-11-19 | 2020-05-28 | Progenity, Inc. | Ingestible device for delivery of therapeutic agent to the gastrointestinal tract |
| CN121197633A (zh) | 2019-12-13 | 2025-12-26 | 比特比德科有限责任公司 | 用于将治疗剂递送至胃肠道的可摄取装置 |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NZ502872A (en) * | 1997-08-28 | 2002-10-25 | Novartis Ag | Mevinolin and compaction as LFA-1 antagonists for treating autoimmune diseases |
| US7388027B2 (en) * | 2004-03-04 | 2008-06-17 | Bristol-Myers Squibb Company | Bicyclic compounds as modulators of androgen receptor function and method |
-
2005
- 2005-10-06 GB GBGB0520378.1A patent/GB0520378D0/en not_active Ceased
-
2006
- 2006-10-04 CA CA002624493A patent/CA2624493A1/en not_active Abandoned
- 2006-10-04 BR BRPI0616880-9A patent/BRPI0616880A2/pt not_active IP Right Cessation
- 2006-10-04 EP EP06819072A patent/EP1933835B1/de not_active Not-in-force
- 2006-10-04 DE DE602006018758T patent/DE602006018758D1/de active Active
- 2006-10-04 RU RU2008117330/04A patent/RU2008117330A/ru not_active Application Discontinuation
- 2006-10-04 KR KR1020087008236A patent/KR20080046226A/ko not_active Ceased
- 2006-10-04 WO PCT/EP2006/067017 patent/WO2007039616A1/en not_active Ceased
- 2006-10-04 JP JP2008534006A patent/JP2009511448A/ja active Pending
- 2006-10-04 US US12/089,155 patent/US20080242710A1/en not_active Abandoned
- 2006-10-04 CN CNA2006800372582A patent/CN101282724A/zh active Pending
- 2006-10-04 AU AU2006298658A patent/AU2006298658A1/en not_active Abandoned
- 2006-10-04 AT AT06819072T patent/ATE490772T1/de not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| CN101282724A (zh) | 2008-10-08 |
| AU2006298658A1 (en) | 2007-04-12 |
| GB0520378D0 (en) | 2005-11-16 |
| CA2624493A1 (en) | 2007-04-12 |
| US20080242710A1 (en) | 2008-10-02 |
| DE602006018758D1 (de) | 2011-01-20 |
| EP1933835B1 (de) | 2010-12-08 |
| KR20080046226A (ko) | 2008-05-26 |
| JP2009511448A (ja) | 2009-03-19 |
| BRPI0616880A2 (pt) | 2011-07-05 |
| WO2007039616A1 (en) | 2007-04-12 |
| EP1933835A1 (de) | 2008-06-25 |
| RU2008117330A (ru) | 2009-11-20 |
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