ATE491025T1 - Subtilasevarianten mit veränderter immunogenität - Google Patents

Subtilasevarianten mit veränderter immunogenität

Info

Publication number
ATE491025T1
ATE491025T1 AT05728219T AT05728219T ATE491025T1 AT E491025 T1 ATE491025 T1 AT E491025T1 AT 05728219 T AT05728219 T AT 05728219T AT 05728219 T AT05728219 T AT 05728219T AT E491025 T1 ATE491025 T1 AT E491025T1
Authority
AT
Austria
Prior art keywords
subtilase variants
altered immunogenicity
subtilases
subtilase
relates
Prior art date
Application number
AT05728219T
Other languages
English (en)
Inventor
Stefan Minning
Henriette Draborg
Erwing Roggen
Nanna Kristensen Soni
Ninna Willestofte Berg
Stina Thulesen Lyngstrand
Original Assignee
Novozymes As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novozymes As filed Critical Novozymes As
Application granted granted Critical
Publication of ATE491025T1 publication Critical patent/ATE491025T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
    • A61K8/66—Enzymes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
    • C12Y304/21—Serine endopeptidases (3.4.21)
    • C12Y304/21062—Subtilisin (3.4.21.62)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/52—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from bacteria or Archaea
    • C12N9/54—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from bacteria or Archaea bacteria being Bacillus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • C—CHEMISTRY; METALLURGY
    • C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
    • C11D3/00—Other compounding ingredients of detergent compositions covered in group C11D1/00
    • C11D3/16—Organic compounds
    • C11D3/38—Products with no well-defined composition, e.g. natural products
    • C11D3/386—Preparations containing enzymes, e.g. protease or amylase
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Medicinal Chemistry (AREA)
  • Birds (AREA)
  • Epidemiology (AREA)
  • Dermatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Detergent Compositions (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
AT05728219T 2004-04-02 2005-04-01 Subtilasevarianten mit veränderter immunogenität ATE491025T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DKPA200400535 2004-04-02
PCT/DK2005/000225 WO2005095592A2 (en) 2004-04-02 2005-04-01 Subtilase variants having altered immunogenicity

Publications (1)

Publication Number Publication Date
ATE491025T1 true ATE491025T1 (de) 2010-12-15

Family

ID=35064451

Family Applications (1)

Application Number Title Priority Date Filing Date
AT05728219T ATE491025T1 (de) 2004-04-02 2005-04-01 Subtilasevarianten mit veränderter immunogenität

Country Status (6)

Country Link
US (2) US7824896B2 (de)
EP (1) EP1735433B1 (de)
CN (2) CN103820423A (de)
AT (1) ATE491025T1 (de)
DE (1) DE602005025202D1 (de)
WO (1) WO2005095592A2 (de)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7824896B2 (en) * 2004-04-02 2010-11-02 Novozymes A/S Subtilase variants having altered lmmunogenicity
EP4530348A3 (de) * 2014-12-15 2025-08-06 Basf Se Waschmittelzusammensetzung mit subtilasevarianten
EP4071244A1 (de) * 2015-06-18 2022-10-12 Novozymes A/S Subtilasevarianten und polynukleotide zur codierung davon
EP3275985A1 (de) * 2016-07-26 2018-01-31 The Procter and Gamble Company Spülmittelzusammensetzung für automatisches geschirrspülen
EP3275989A1 (de) * 2016-07-26 2018-01-31 The Procter and Gamble Company Spülmittelzusammensetzung für automatisches geschirrspülen
US11798657B2 (en) * 2019-09-16 2023-10-24 Burzin Bhavnagri System and method for creating lead compounds, and compositions thereof
EP4525615A2 (de) 2022-05-14 2025-03-26 Novozymes A/S Zusammensetzungen und verfahren zur prävention, behandlung, unterdrückung und/oder beseitigung von phytopathogenen befällen und infektionen
CN121780492A (zh) * 2022-10-27 2026-04-03 青岛蔚蓝生物集团有限公司 一种高比活碱性蛋白酶突变体

Family Cites Families (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK6488D0 (da) * 1988-01-07 1988-01-07 Novo Industri As Enzymer
US5665587A (en) * 1989-06-26 1997-09-09 Novo Nordisk A/S Modified subtilisins and detergent compositions containing same
FI932561L (fi) * 1990-12-05 1993-06-04 Novo Nordisk As Proteiner med foeraendrade epitoper och foerfaranden foer deras framstaellning
ES2121014T3 (es) * 1991-05-01 1998-11-16 Novo Nordisk As Enzimas estabilizadas y composiciones detergentes.
US6599730B1 (en) * 1994-05-02 2003-07-29 Procter & Gamble Company Subtilisin 309 variants having decreased adsorption and increased hydrolysis
US5837517A (en) * 1995-05-05 1998-11-17 Novo Nordisk A/S Protease variants and compositions
EP0932667B1 (de) * 1996-11-04 2008-10-01 Novozymes A/S Subtilase varianten und verbindungen
US6773907B2 (en) * 1997-11-21 2004-08-10 Peter Kamp Hansen Subtilase enzymes
US6835550B1 (en) * 1998-04-15 2004-12-28 Genencor International, Inc. Mutant proteins having lower allergenic response in humans and methods for constructing, identifying and producing such proteins
US6461849B1 (en) * 1998-10-13 2002-10-08 Novozymes, A/S Modified polypeptide
AU6078899A (en) * 1998-10-13 2000-05-01 Novozymes A/S A modified polypeptide with reduced immune response
US6376450B1 (en) * 1998-10-23 2002-04-23 Chanchal Kumar Ghosh Cleaning compositions containing multiply-substituted protease variants
ES2220114T3 (es) 1998-10-30 2004-12-01 Novozymes A/S Variantes de proteinas poco alergenicas.
ATE355355T1 (de) * 1998-12-18 2006-03-15 Novozymes As Subtilasen der i-s1 und i-s2 untergruppen mit einem zusätzlichen aminosäurerest in der aktiven seitenschleifenregion
BR0012660A (pt) * 1999-07-22 2002-04-09 Procter & Gamble Variante de protease tipo subtilisina; composição de limpeza; e composição de cuidado pessoal
US6727085B2 (en) * 1999-12-15 2004-04-27 Fanoe Tina Sejersgaard Subtilase variants having an improved wash performance on egg stains
EP1244779B1 (de) * 1999-12-15 2014-05-07 Novozymes A/S Subtilasevarianten mit verbesserter waschleistung bei eierflecken
JP2004508011A (ja) * 2000-04-03 2004-03-18 マキシジェン，　インコーポレイテッド スブチリシン変異体
CN100591763C (zh) * 2000-08-21 2010-02-24 诺维信公司 枯草杆菌酶
PL210859B1 (pl) * 2001-03-23 2012-03-30 Genencor Int Odmiana subtylizyny zawierająca zmieniony epitop limfocytów T, kwas nukleinowy kodujący tę odmianę subtylizyny, wektor ekspresyjny i komórka gospodarza zawierająca kwas nukleinowy oraz kompozycje zawierające tę odmianę subtylizyny
DE10163883A1 (de) * 2001-12-22 2003-07-10 Henkel Kgaa Neue Alkalische Protease aus Bacillus sp. (DSM 14390) und Wasch- und Reinigungsmittel enthaltend diese neue Alkalische Protease
US20050054843A1 (en) * 2001-12-31 2005-03-10 Estell David A Proteases producing an altered immunological response and methods of making and using the same
ES2336092T3 (es) * 2002-01-16 2010-04-08 Genencor International, Inc. Variantes de proteasas con multiples sustituciones.
EP1520017A2 (de) 2002-06-26 2005-04-06 Novozymes A/S Subtilasen und subtilasevarianten mit veränderter immunogenität
US7888093B2 (en) * 2002-11-06 2011-02-15 Novozymes A/S Subtilase variants
US7824896B2 (en) * 2004-04-02 2010-11-02 Novozymes A/S Subtilase variants having altered lmmunogenicity

Also Published As

Publication number Publication date
WO2005095592A2 (en) 2005-10-13
CN1969042A (zh) 2007-05-23
CN1969042B (zh) 2014-09-24
EP1735433B1 (de) 2010-12-08
US7824896B2 (en) 2010-11-02
US8389262B2 (en) 2013-03-05
EP1735433A2 (de) 2006-12-27
US20080280344A1 (en) 2008-11-13
CN103820423A (zh) 2014-05-28
WO2005095592A3 (en) 2006-12-14
US20110009308A1 (en) 2011-01-13
DE602005025202D1 (de) 2011-01-20

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Legal Events

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