ATE491025T1 - Subtilasevarianten mit veränderter immunogenität - Google Patents

Subtilasevarianten mit veränderter immunogenität

Info

Publication number
ATE491025T1
ATE491025T1 AT05728219T AT05728219T ATE491025T1 AT E491025 T1 ATE491025 T1 AT E491025T1 AT 05728219 T AT05728219 T AT 05728219T AT 05728219 T AT05728219 T AT 05728219T AT E491025 T1 ATE491025 T1 AT E491025T1
Authority
AT
Austria
Prior art keywords
subtilase variants
altered immunogenicity
subtilases
subtilase
relates
Prior art date
Application number
AT05728219T
Other languages
English (en)
Inventor
Stefan Minning
Henriette Draborg
Erwing Roggen
Nanna Kristensen Soni
Ninna Willestofte Berg
Stina Thulesen Lyngstrand
Original Assignee
Novozymes As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novozymes As filed Critical Novozymes As
Application granted granted Critical
Publication of ATE491025T1 publication Critical patent/ATE491025T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
    • A61K8/66—Enzymes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
    • C12Y304/21—Serine endopeptidases (3.4.21)
    • C12Y304/21062—Subtilisin (3.4.21.62)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/52—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from bacteria or Archaea
    • C12N9/54—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from bacteria or Archaea bacteria being Bacillus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • C—CHEMISTRY; METALLURGY
    • C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
    • C11D3/00—Other compounding ingredients of detergent compositions covered in group C11D1/00
    • C11D3/16—Organic compounds
    • C11D3/38—Products with no well-defined composition, e.g. natural products
    • C11D3/386—Preparations containing enzymes, e.g. protease or amylase
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Medicinal Chemistry (AREA)
  • Birds (AREA)
  • Epidemiology (AREA)
  • Dermatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Detergent Compositions (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
AT05728219T 2004-04-02 2005-04-01 Subtilasevarianten mit veränderter immunogenität ATE491025T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DKPA200400535 2004-04-02
PCT/DK2005/000225 WO2005095592A2 (en) 2004-04-02 2005-04-01 Subtilase variants having altered immunogenicity

Publications (1)

Publication Number Publication Date
ATE491025T1 true ATE491025T1 (de) 2010-12-15

Family

ID=35064451

Family Applications (1)

Application Number Title Priority Date Filing Date
AT05728219T ATE491025T1 (de) 2004-04-02 2005-04-01 Subtilasevarianten mit veränderter immunogenität

Country Status (6)

Country Link
US (2) US7824896B2 (de)
EP (1) EP1735433B1 (de)
CN (2) CN1969042B (de)
AT (1) ATE491025T1 (de)
DE (1) DE602005025202D1 (de)
WO (1) WO2005095592A2 (de)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7824896B2 (en) * 2004-04-02 2010-11-02 Novozymes A/S Subtilase variants having altered lmmunogenicity
PL3608403T3 (pl) * 2014-12-15 2025-06-23 Henkel Ag & Co. Kgaa Kompozycja detergentowa zawierająca warianty subtylazy
CN121406620A (zh) * 2015-06-18 2026-01-27 诺维信公司 枯草杆菌酶变体以及编码它们的多核苷酸
EP3275989A1 (de) * 2016-07-26 2018-01-31 The Procter and Gamble Company Spülmittelzusammensetzung für automatisches geschirrspülen
EP3275985A1 (de) * 2016-07-26 2018-01-31 The Procter and Gamble Company Spülmittelzusammensetzung für automatisches geschirrspülen
US11798657B2 (en) * 2019-09-16 2023-10-24 Burzin Bhavnagri System and method for creating lead compounds, and compositions thereof
WO2023225459A2 (en) 2022-05-14 2023-11-23 Novozymes A/S Compositions and methods for preventing, treating, supressing and/or eliminating phytopathogenic infestations and infections
CN121592627A (zh) * 2022-10-27 2026-03-03 青岛蔚蓝生物集团有限公司 一种比活力提高的碱性蛋白酶突变体

Family Cites Families (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK6488D0 (da) * 1988-01-07 1988-01-07 Novo Industri As Enzymer
US5665587A (en) * 1989-06-26 1997-09-09 Novo Nordisk A/S Modified subtilisins and detergent compositions containing same
DK0561907T3 (da) 1990-12-05 1999-05-31 Novo Nordisk As Proteiner med ændrede epitoper og fremgangsmåder til fremstilling deraf
KR100258460B1 (ko) * 1991-05-01 2000-06-01 한센 핀 베네드 안정화 효소 및 세제 조성물
US6599730B1 (en) * 1994-05-02 2003-07-29 Procter & Gamble Company Subtilisin 309 variants having decreased adsorption and increased hydrolysis
US5837517A (en) * 1995-05-05 1998-11-17 Novo Nordisk A/S Protease variants and compositions
KR100591553B1 (ko) * 1996-11-04 2006-06-19 노보자임스 에이/에스 섭틸라제 변종과 조성물
US6773907B2 (en) * 1997-11-21 2004-08-10 Peter Kamp Hansen Subtilase enzymes
US6835550B1 (en) * 1998-04-15 2004-12-28 Genencor International, Inc. Mutant proteins having lower allergenic response in humans and methods for constructing, identifying and producing such proteins
US6461849B1 (en) * 1998-10-13 2002-10-08 Novozymes, A/S Modified polypeptide
JP2002527059A (ja) * 1998-10-13 2002-08-27 ノボザイムス アクティーゼルスカブ 低められた免疫応答を有する修飾されたポリペプチド
US6376450B1 (en) * 1998-10-23 2002-04-23 Chanchal Kumar Ghosh Cleaning compositions containing multiply-substituted protease variants
ATE263778T1 (de) * 1998-10-30 2004-04-15 Novozymes As Niedrigallergene proteinvarianten
CA2355580C (en) * 1998-12-18 2011-03-15 Novozymes A/S Subtilase enzymes of the i-s1 and i-s2 sub-groups having an additional amino acid residue in the active site loop region
WO2001007578A2 (en) * 1999-07-22 2001-02-01 The Procter & Gamble Company Subtilisin protease variants having amino acid substitutions in defined epitope regions
US6727085B2 (en) * 1999-12-15 2004-04-27 Fanoe Tina Sejersgaard Subtilase variants having an improved wash performance on egg stains
WO2001044452A1 (en) * 1999-12-15 2001-06-21 Novozymes A/S Subtilase variants having an improved wash performance on egg stains
AU2001249811B2 (en) * 2000-04-03 2006-06-08 Maxygen, Inc. Subtilisin variants
WO2002016547A2 (en) 2000-08-21 2002-02-28 Novozymes A/S Subtilase enzymes
ATE527276T1 (de) * 2001-03-23 2011-10-15 Genencor Int Proteine, die veränderte immunogene reaktionen bewirken, und verfahren zu deren herstellung und anwendung
DE10163883A1 (de) * 2001-12-22 2003-07-10 Henkel Kgaa Neue Alkalische Protease aus Bacillus sp. (DSM 14390) und Wasch- und Reinigungsmittel enthaltend diese neue Alkalische Protease
JP2005514026A (ja) 2001-12-31 2005-05-19 ジェネンコー・インターナショナル・インク 免疫反応の変化を生じるプロテアーゼ、ならびにその製造および利用方法
ATE450606T1 (de) * 2002-01-16 2009-12-15 Genencor Int Mehrfachsubstituierte proteasevarianten
CN101597601B (zh) 2002-06-26 2013-06-05 诺维信公司 具有改变的免疫原性的枯草杆菌酶和枯草杆菌酶变体
US7888093B2 (en) * 2002-11-06 2011-02-15 Novozymes A/S Subtilase variants
US7824896B2 (en) * 2004-04-02 2010-11-02 Novozymes A/S Subtilase variants having altered lmmunogenicity

Also Published As

Publication number Publication date
WO2005095592A2 (en) 2005-10-13
WO2005095592A3 (en) 2006-12-14
US20110009308A1 (en) 2011-01-13
CN103820423A (zh) 2014-05-28
CN1969042A (zh) 2007-05-23
CN1969042B (zh) 2014-09-24
EP1735433B1 (de) 2010-12-08
US20080280344A1 (en) 2008-11-13
DE602005025202D1 (de) 2011-01-20
US8389262B2 (en) 2013-03-05
US7824896B2 (en) 2010-11-02
EP1735433A2 (de) 2006-12-27

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