ATE450606T1 - Mehrfachsubstituierte proteasevarianten - Google Patents

Mehrfachsubstituierte proteasevarianten

Info

Publication number
ATE450606T1
ATE450606T1 AT03731960T AT03731960T ATE450606T1 AT E450606 T1 ATE450606 T1 AT E450606T1 AT 03731960 T AT03731960 T AT 03731960T AT 03731960 T AT03731960 T AT 03731960T AT E450606 T1 ATE450606 T1 AT E450606T1
Authority
AT
Austria
Prior art keywords
protease
amino acid
precursor
variants
naturally
Prior art date
Application number
AT03731960T
Other languages
English (en)
Inventor
Richard Bott
David Estell
Kellis, Jr
Ayrookaran Poulose
Original Assignee
Genencor Int
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genencor Int filed Critical Genencor Int
Application granted granted Critical
Publication of ATE450606T1 publication Critical patent/ATE450606T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/52—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from bacteria or Archaea
    • C12N9/54—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from bacteria or Archaea bacteria being Bacillus
    • C—CHEMISTRY; METALLURGY
    • C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
    • C11D3/00—Other compounding ingredients of detergent compositions covered in group C11D1/00
    • C11D3/16—Organic compounds
    • C11D3/38—Products with no well-defined composition, e.g. natural products
    • C11D3/386—Preparations containing enzymes, e.g. protease or amylase
    • C—CHEMISTRY; METALLURGY
    • C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
    • C11D3/00—Other compounding ingredients of detergent compositions covered in group C11D1/00
    • C11D3/16—Organic compounds
    • C11D3/38—Products with no well-defined composition, e.g. natural products
    • C11D3/386—Preparations containing enzymes, e.g. protease or amylase
    • C11D3/38609—Protease or amylase in solid compositions only
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
    • C12Y304/21—Serine endopeptidases (3.4.21)
    • C12Y304/21062—Subtilisin (3.4.21.62)

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Detergent Compositions (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Meat, Egg Or Seafood Products (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
AT03731960T 2002-01-16 2003-01-16 Mehrfachsubstituierte proteasevarianten ATE450606T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US35022202P 2002-01-16 2002-01-16
PCT/US2003/001448 WO2003062381A2 (en) 2002-01-16 2003-01-16 Multiply-substituted protease variants

Publications (1)

Publication Number Publication Date
ATE450606T1 true ATE450606T1 (de) 2009-12-15

Family

ID=27613372

Family Applications (1)

Application Number Title Priority Date Filing Date
AT03731960T ATE450606T1 (de) 2002-01-16 2003-01-16 Mehrfachsubstituierte proteasevarianten

Country Status (13)

Country Link
US (8) US7306937B2 (de)
EP (1) EP1523553B1 (de)
JP (2) JP4703113B2 (de)
AT (1) ATE450606T1 (de)
AU (1) AU2003210552A1 (de)
BR (1) BRPI0306955B1 (de)
CA (2) CA2472725C (de)
DE (1) DE60330346D1 (de)
DK (1) DK1523553T3 (de)
ES (1) ES2336092T3 (de)
MX (1) MXPA04006809A (de)
PT (1) PT1523553E (de)
WO (1) WO2003062381A2 (de)

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US7824896B2 (en) * 2004-04-02 2010-11-02 Novozymes A/S Subtilase variants having altered lmmunogenicity
WO2007061886A2 (en) * 2005-11-18 2007-05-31 Verenium Corporation Compositions and methods for ameliorating toxins and virulence factors
EP2030015B1 (de) * 2006-06-02 2016-02-17 President and Fellows of Harvard College Neugestaltung von proteinoberflächen
CN101473036B (zh) 2006-06-23 2012-12-12 丹尼斯科美国公司 利用用于工程改造多种性质的位点评价文库对序列和活性关系进行系统评价
KR20090031906A (ko) * 2006-07-18 2009-03-30 다니스코 유에스 인크. 광범위한 온도에 걸쳐 활성인 프로테아제 변이형
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JP2011523353A (ja) * 2008-04-28 2011-08-11 プレジデント アンド フェロウズ オブ ハーバード カレッジ 細胞透過のための過剰に荷電されたタンパク質
CN102046783A (zh) * 2008-06-06 2011-05-04 丹尼斯科美国公司 包含变体微生物蛋白酶的组合物和方法
US20100192985A1 (en) 2008-11-11 2010-08-05 Wolfgang Aehle Compositions and methods comprising serine protease variants
RU2560978C2 (ru) * 2008-11-11 2015-08-20 ДАНИСКО ЮЭс ИНК. Протеазы, содержащие одну или несколько комбинируемых мутаций
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AR079338A1 (es) 2009-12-09 2012-01-18 Danisco Us Inc Variantes de proteasa de bacillus y acidos nucleicos que codifican dichas variantes
CN102652175B (zh) * 2009-12-09 2016-02-10 宝洁公司 织物和家居护理产品
JP6448904B2 (ja) * 2010-05-06 2019-01-09 ダニスコ・ユーエス・インク サブチリシン変異体を含む組成物及び方法
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JP2015504660A (ja) * 2011-12-20 2015-02-16 ノボザイムス アクティーゼルスカブ サブチラーゼ変異体およびそれをコードするポリヌクレオチド
WO2017089093A1 (en) 2015-11-25 2017-06-01 Unilever N.V. A liquid detergent composition
EP3702452A1 (de) * 2019-03-01 2020-09-02 Novozymes A/S Waschmittelzusammensetzungen mit zwei proteasen
CN110846299B (zh) * 2019-11-22 2021-09-24 江南大学 一种前导肽突变体及其在角蛋白酶生产中的应用
EP4525615A2 (de) 2022-05-14 2025-03-26 Novozymes A/S Zusammensetzungen und verfahren zur prävention, behandlung, unterdrückung und/oder beseitigung von phytopathogenen befällen und infektionen
WO2025202372A1 (en) 2024-03-27 2025-10-02 Basf Se Polypeptides having protease activity for use in detergent compositions
WO2025202370A1 (en) 2024-03-27 2025-10-02 Basf Se Polypeptides having protease activity for use in detergent compositions
WO2025202369A1 (en) 2024-03-27 2025-10-02 Basf Se Polypeptides having protease activity for use in detergent compositions
WO2025202379A1 (en) 2024-03-27 2025-10-02 Basf Se Polypeptides having protease activity for use in detergent compositions
EP4624572A1 (de) 2024-03-27 2025-10-01 Basf Se Polypeptide mit proteaseaktivität zur verwendung in waschmittelzusammensetzungen
WO2025202382A1 (en) 2024-03-27 2025-10-02 Basf Se Polypeptides having protease activity for use in cleaning compositions
WO2025202374A1 (en) 2024-03-27 2025-10-02 Basf Se Polypeptides having protease activity for use in detergent compositions

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US20100192985A1 (en) * 2008-11-11 2010-08-05 Wolfgang Aehle Compositions and methods comprising serine protease variants

Also Published As

Publication number Publication date
DE60330346D1 (de) 2010-01-14
WO2003062381A3 (en) 2005-02-24
JP4703113B2 (ja) 2011-06-15
CA2894330A1 (en) 2003-07-31
US20110091958A1 (en) 2011-04-21
CA2472725C (en) 2015-08-11
AU2003210552A1 (en) 2003-09-02
US20050221461A1 (en) 2005-10-06
US7306937B2 (en) 2007-12-11
WO2003062381A2 (en) 2003-07-31
US20110086412A1 (en) 2011-04-14
PT1523553E (pt) 2010-03-03
US20090011489A1 (en) 2009-01-08
MXPA04006809A (es) 2004-10-11
CA2472725A1 (en) 2003-07-31
EP1523553B1 (de) 2009-12-02
ES2336092T3 (es) 2010-04-08
US20110091959A1 (en) 2011-04-21
BR0306955A (pt) 2006-12-19
EP1523553A2 (de) 2005-04-20
US20080176313A1 (en) 2008-07-24
DK1523553T3 (da) 2010-04-19
JP2011041571A (ja) 2011-03-03
EP1523553A4 (de) 2006-06-21
JP2005519592A (ja) 2005-07-07
US20130171717A1 (en) 2013-07-04
US20080124783A1 (en) 2008-05-29
BRPI0306955B1 (pt) 2016-03-22

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