ATE492269T1 - Verfahren für die zubereitung einer isotonischen wässrigen ropivacain-injektion - Google Patents
Verfahren für die zubereitung einer isotonischen wässrigen ropivacain-injektionInfo
- Publication number
- ATE492269T1 ATE492269T1 AT06770886T AT06770886T ATE492269T1 AT E492269 T1 ATE492269 T1 AT E492269T1 AT 06770886 T AT06770886 T AT 06770886T AT 06770886 T AT06770886 T AT 06770886T AT E492269 T1 ATE492269 T1 AT E492269T1
- Authority
- AT
- Austria
- Prior art keywords
- ropivacain
- injection
- isotonic aqueous
- ropivacaine
- base
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P23/00—Anaesthetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P23/00—Anaesthetics
- A61P23/02—Local anaesthetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/02—Inorganic compounds
Landscapes
- Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Anesthesiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Dermatology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
- Hydrogenated Pyridines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US11/137,256 US20060270708A1 (en) | 2005-05-25 | 2005-05-25 | Novel process for preparation of isotonic aqueous injection of ropivacaine |
| PCT/US2006/019804 WO2006127639A2 (en) | 2005-05-25 | 2006-05-22 | Process for preparation of isotonic aqueous injection of ropivacaine |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE492269T1 true ATE492269T1 (de) | 2011-01-15 |
Family
ID=37027513
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT06770886T ATE492269T1 (de) | 2005-05-25 | 2006-05-22 | Verfahren für die zubereitung einer isotonischen wässrigen ropivacain-injektion |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US20060270708A1 (de) |
| EP (1) | EP1883392B1 (de) |
| JP (1) | JP2008545694A (de) |
| AT (1) | ATE492269T1 (de) |
| AU (1) | AU2006251583A1 (de) |
| CA (1) | CA2608730A1 (de) |
| CY (1) | CY1111445T1 (de) |
| DE (1) | DE602006019085D1 (de) |
| DK (1) | DK1883392T3 (de) |
| ES (1) | ES2358884T3 (de) |
| PL (1) | PL1883392T3 (de) |
| PT (1) | PT1883392E (de) |
| SI (1) | SI1883392T1 (de) |
| WO (1) | WO2006127639A2 (de) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ITMI20051144A1 (it) * | 2005-06-17 | 2006-12-18 | Molteni & C Dei Fratellei Alit | "procedimento per la preparazione d'una soluzione iniettabile di (2s)-n-(2;6-dimetil-fenil)-1-propil-2-piperidincarbossiamide" |
| CN102697708A (zh) * | 2012-04-17 | 2012-10-03 | 上海禾丰制药有限公司 | 盐酸罗哌卡因注射液及其制剂工艺 |
| LT3331516T (lt) * | 2015-07-13 | 2024-12-27 | Neon Laboratories Ltd. | Ropivakaino hidrochlorido hiperbarinis injekcinis tirpalas ir jo paruošimo procesas |
| CN105816432B (zh) * | 2016-03-24 | 2020-02-07 | 成都天台山制药有限公司 | 注射用冷冻干燥盐酸罗哌卡因组合物及其质量控制方法 |
| CN106177970B (zh) * | 2016-07-12 | 2019-09-17 | 扬子江药业集团有限公司 | 罗哌卡因注射用制剂及其制备方法和应用 |
| JP2020519593A (ja) * | 2017-05-11 | 2020-07-02 | ステディメッド, エルティーディー.Steadymed, Ltd. | 溶解度を増強させた薬物含有製剤 |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2797241A (en) * | 1953-08-28 | 1957-06-25 | Brown Charles Leslie Meredith | Diethyl-glycinexylidide and process |
| US4695576A (en) * | 1984-07-09 | 1987-09-22 | Astra Lake Medel Aktiebolag | L-N-n-propylpipecolic acid-2,6-xylidide |
| SE451840B (sv) * | 1986-01-03 | 1987-11-02 | Astra Laekemedel Ab | Optiskt rent monohydrat av s-(-)-1-propyl-2',6'-pipekoloxylididhydroklorid, sett att framstella denna och farmaceutiska beredningar for lokalbedovning |
| SE9302218D0 (sv) * | 1993-06-28 | 1993-06-28 | Ab Astra | New use |
| US6156900A (en) * | 1994-10-07 | 2000-12-05 | Darwin Discovery Limited | Racemization of precursors to levobupivacaine and analogues thereof |
| MX9703025A (es) * | 1994-10-25 | 1997-10-31 | Chiroscience Ltd | Proceso para preparar levobupivacaina y sus analogos. |
| SE9501808D0 (sv) * | 1995-05-16 | 1995-05-16 | Astra Ab | New process |
| BR9707081A (pt) * | 1996-01-25 | 1999-05-25 | Schering Ag | Soluções de injeção e infusão concentradas aperfeiçoadas para aplicação intravasal |
| IL129951A0 (en) * | 1997-07-02 | 2000-02-29 | Euro Celtique Sa | Prolonged anesthesia in joints and body spaces |
| BR9814883A (pt) * | 1997-11-19 | 2000-10-03 | Darwin Discovery Ltd | Formulação anestésica |
| BR0002246A (pt) * | 2000-04-06 | 2003-04-15 | Cristalia Prod Quimicos Farm | Processo de obtenção dos enantiÈmeros da bupivacaìna racêmica, processo de obtenção de composições farmacêuticas a base de levobupivacaìna: composições farmacêuticas a base de levobupivacaìna formuladas nas formas básicas ou sais farmaceuticamente aceitáveis e utilização das composições farmacêuticas a base de levobupivacaìna formuladas nas formas básicas ou sais farmaceuticamente aceitáveis |
| JPWO2003024930A1 (ja) * | 2001-09-10 | 2004-12-24 | メルシャン株式会社 | ピペコリン酸アミド誘導体の製造方法 |
-
2005
- 2005-05-25 US US11/137,256 patent/US20060270708A1/en not_active Abandoned
-
2006
- 2006-05-22 PT PT06770886T patent/PT1883392E/pt unknown
- 2006-05-22 PL PL06770886T patent/PL1883392T3/pl unknown
- 2006-05-22 DK DK06770886.7T patent/DK1883392T3/da active
- 2006-05-22 SI SI200630959T patent/SI1883392T1/sl unknown
- 2006-05-22 ES ES06770886T patent/ES2358884T3/es not_active Expired - Lifetime
- 2006-05-22 DE DE602006019085T patent/DE602006019085D1/de not_active Expired - Lifetime
- 2006-05-22 WO PCT/US2006/019804 patent/WO2006127639A2/en not_active Ceased
- 2006-05-22 AU AU2006251583A patent/AU2006251583A1/en not_active Abandoned
- 2006-05-22 JP JP2008513602A patent/JP2008545694A/ja active Pending
- 2006-05-22 AT AT06770886T patent/ATE492269T1/de active
- 2006-05-22 CA CA002608730A patent/CA2608730A1/en not_active Abandoned
- 2006-05-22 EP EP06770886A patent/EP1883392B1/de not_active Revoked
-
2011
- 2011-03-22 CY CY20111100313T patent/CY1111445T1/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| ES2358884T3 (es) | 2011-05-16 |
| PL1883392T3 (pl) | 2011-07-29 |
| WO2006127639A2 (en) | 2006-11-30 |
| CA2608730A1 (en) | 2006-11-30 |
| SI1883392T1 (sl) | 2011-07-29 |
| JP2008545694A (ja) | 2008-12-18 |
| DK1883392T3 (da) | 2011-04-18 |
| AU2006251583A1 (en) | 2006-11-30 |
| CY1111445T1 (el) | 2015-08-05 |
| US20060270708A1 (en) | 2006-11-30 |
| EP1883392A2 (de) | 2008-02-06 |
| EP1883392B1 (de) | 2010-12-22 |
| WO2006127639A3 (en) | 2007-05-18 |
| DE602006019085D1 (de) | 2011-02-03 |
| PT1883392E (pt) | 2011-03-29 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification |
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