ATE492528T1 - Derivate und pharmazeutische zusammensetzungen von n-hydroxyalkyltetramethyl cyclo propan carboxamid mit antiepileptischer und verfahren zu deren herstellung - Google Patents
Derivate und pharmazeutische zusammensetzungen von n-hydroxyalkyltetramethyl cyclo propan carboxamid mit antiepileptischer und verfahren zu deren herstellungInfo
- Publication number
- ATE492528T1 ATE492528T1 AT02806661T AT02806661T ATE492528T1 AT E492528 T1 ATE492528 T1 AT E492528T1 AT 02806661 T AT02806661 T AT 02806661T AT 02806661 T AT02806661 T AT 02806661T AT E492528 T1 ATE492528 T1 AT E492528T1
- Authority
- AT
- Austria
- Prior art keywords
- pharmaceutical compositions
- derivatives
- hydroxyalkyltetramethyl
- antiepileptic
- production
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 2
- 239000008194 pharmaceutical composition Substances 0.000 title abstract 2
- 230000003556 anti-epileptic effect Effects 0.000 title 1
- 239000001961 anticonvulsive agent Substances 0.000 title 1
- AIMMVWOEOZMVMS-UHFFFAOYSA-N cyclopropanecarboxamide Chemical compound NC(=O)C1CC1 AIMMVWOEOZMVMS-UHFFFAOYSA-N 0.000 title 1
- 208000019695 Migraine disease Diseases 0.000 abstract 1
- 208000019022 Mood disease Diseases 0.000 abstract 1
- 208000012902 Nervous system disease Diseases 0.000 abstract 1
- 208000025966 Neurological disease Diseases 0.000 abstract 1
- 208000002193 Pain Diseases 0.000 abstract 1
- 208000028017 Psychotic disease Diseases 0.000 abstract 1
- 125000003917 carbamoyl group Chemical class [H]N([H])C(*)=O 0.000 abstract 1
- 206010015037 epilepsy Diseases 0.000 abstract 1
- 206010027599 migraine Diseases 0.000 abstract 1
- 230000000926 neurological effect Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IL147953A IL147953A (en) | 2002-02-01 | 2002-02-01 | Derivatives and pharmaceutical compositions of n-hydroxymethyl tetramethylcyclopropyl- |
| PCT/IL2002/001050 WO2003064374A1 (en) | 2002-02-01 | 2002-12-29 | Derivatives and pharmaceutical compositions of n-hydroxyalkyl tetramethylcyclopropane-carboxamide, having anti-epileptic, neurological, and cns activity, and method for their preparation |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE492528T1 true ATE492528T1 (de) | 2011-01-15 |
Family
ID=27638031
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT02806661T ATE492528T1 (de) | 2002-02-01 | 2002-12-29 | Derivate und pharmazeutische zusammensetzungen von n-hydroxyalkyltetramethyl cyclo propan carboxamid mit antiepileptischer und verfahren zu deren herstellung |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US6960687B2 (de) |
| EP (1) | EP1487787B1 (de) |
| AT (1) | ATE492528T1 (de) |
| DE (1) | DE60238717D1 (de) |
| IL (1) | IL147953A (de) |
| WO (1) | WO2003064374A1 (de) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL157751A0 (en) | 2003-02-28 | 2004-03-28 | Yissum Res Dev Co | New amide derivatives of 2,2,3,3-tetramethylcyclopropane carboxylic acid, a method for their synthesis and pharmaceutical compositions containing them |
| IL156203A0 (en) * | 2003-05-29 | 2003-12-23 | Yissum Res Dev Co | Use of 2,2,3,3, tetramethylcyclopropane carboxylic acid derivatives for treating psychiatric disorders |
| FR2856595B1 (fr) * | 2003-06-27 | 2008-05-30 | Exonhit Therapeutics Sa | Methodes et compositions pour le traitement de deficits cognitifs. |
| US20060004098A1 (en) | 2003-07-28 | 2006-01-05 | Yissum Research Development Company Of The Hebrew University Of Jerusalem | Compounds useful for treating neurological disorders |
| MXPA06011420A (es) | 2004-04-01 | 2007-04-20 | Cardiome Pharma Corp | Compuestos pegilados de modulacion de canal de iones. |
| JP2010519287A (ja) * | 2007-02-21 | 2010-06-03 | イッサム リサーチ ディベロップメント カンパニー オブ ザ ヘブリュー ユニバーシティー オブ エルサレム リミテッド | α−ハロシクロプロピルカルボキシ化合物およびα−アルキルシクロプロピルカルボキシ化合物ならびにそれらの使用 |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ZA74202B (en) * | 1973-01-11 | 1974-11-27 | Hexachimie | New amine derivatives of 2,2-diaryl cyclopropanes |
| SE9303274D0 (sv) | 1993-10-07 | 1993-10-07 | Astra Ab | Novel phenylethyl and phenylproplamines |
| IL108595A (en) * | 1994-02-08 | 1998-09-24 | Yissum Res Dev Co | History of Carboxylic Acid 2,2,3,3 Tetramethyl Cyclophen (ACMT) (Process for their Preparation and Pharmaceutical Preparations Containing Them) |
| US6011170A (en) | 1997-01-14 | 2000-01-04 | Kaneka Corporation | Process for producing of cysteine derivatives |
| IL120006A (en) * | 1997-01-14 | 2000-12-06 | Yissum Res Dev Co | Valnoctamide stereoisomers and a method for their synthesis and separation |
| US6090854A (en) * | 1998-03-20 | 2000-07-18 | Bristol-Meyers Company | Aryloxyanilides and related compounds |
| IL124118A (en) | 1998-04-16 | 2007-09-20 | Yissum Res Dev Co | Propylisopropyl acetic acid and propylisopropyl acetamide stereoisomers, method for their synthesis and pharmaceutical compositions containing them |
| UA74852C2 (en) * | 2000-12-08 | 2006-02-15 | 3M Innovative Properties Co | Urea-substituted imidazoquinoline ethers |
| US6610326B2 (en) * | 2001-02-16 | 2003-08-26 | Andrx Corporation | Divalproex sodium tablets |
-
2002
- 2002-02-01 IL IL147953A patent/IL147953A/en not_active IP Right Cessation
- 2002-12-29 US US10/503,235 patent/US6960687B2/en not_active Expired - Fee Related
- 2002-12-29 AT AT02806661T patent/ATE492528T1/de not_active IP Right Cessation
- 2002-12-29 DE DE60238717T patent/DE60238717D1/de not_active Expired - Lifetime
- 2002-12-29 EP EP02806661A patent/EP1487787B1/de not_active Expired - Lifetime
- 2002-12-29 WO PCT/IL2002/001050 patent/WO2003064374A1/en not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| IL147953A (en) | 2008-04-13 |
| US20050131069A1 (en) | 2005-06-16 |
| EP1487787A1 (de) | 2004-12-22 |
| IL147953A0 (en) | 2003-07-31 |
| WO2003064374A1 (en) | 2003-08-07 |
| EP1487787B1 (de) | 2010-12-22 |
| US6960687B2 (en) | 2005-11-01 |
| DE60238717D1 (de) | 2011-02-03 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| DE602004032522D1 (de) | Mit n-alkylhydroxamsäuren substituierte isoindolylverbindungen und deren pharmazeutische verwendung | |
| EA200601269A1 (ru) | Лекарственное средство, содержащее производные фенилпиперазина | |
| ATE441628T1 (de) | Tricyclische hydroxamat- und benzamidderivate, zusammensetzungen und verfahren | |
| EA200200293A1 (ru) | Бициклические аминокислоты в качестве фармацевтических агентов | |
| IS6922A (is) | Heterófjölhringjaefnasambönd og notkun þeirra semmetabótrópísk mótlyf gegn glútamat viðtökum | |
| GEP20022676B (en) | 4-Phenyl-Pyridine Derivatives, Method for Their Production and Their Use for Treatment of Disorders Caused by Antagonist of NK-1 Receptors | |
| DE60319865D1 (de) | Substituierte amin-derivate und deren verwendung zur behandlung von angionese-bedingten erkrankungen | |
| CY1116754T1 (el) | Παραγωγα νιτροκατεχολης ως αναστολεις της comt | |
| EA199800798A1 (ru) | Новые замешенные циклические аминокислоты в качестве фармацевтических агентов | |
| EP1471909A4 (de) | Pharmazeutische zusammensetzung und verfahren zur behandlung von erkrankungen des zentralen nervensystems | |
| DE602004000260D1 (de) | Diaryl- und arylheteroarylharnstoffderivate als modulatoren des 5-ht2a-serotoninrezeptors, die sich zur prophylaxe und behandlung von damit im zusammenhang stehenden erkrankungen eignen | |
| EA200500169A1 (ru) | Замещенные производные 1,3-дифенилпроп-2-ен-1-она, получение и применение | |
| DK1362039T3 (da) | Heterocykliske, substituerede carbonylderivater og deres anvendelse som dopamin D3-receptorligander | |
| NO20030724L (no) | Anvendelse av derivater av valproinsyreamider og 2- valproensyreamider for terapi eller prevensjon av smerte- og/eller hodepinelidelser | |
| CY1110775T1 (el) | Υποκατεστημενα αμιδια του θειενοπυρρολιου του καρβοξυλικου οξεος, αμιδια της πυρρολοθειαζολης του καρβοξυλικου οξεος και σχετικα αναλογα ως αναστολεις της κινασης i εψιλον της καζεϊνης | |
| DE60315479D1 (de) | Pyrimidinamid derivate und deren verwendung | |
| DE60312736D1 (de) | 1,2,4-triaminobenzolderivate zur behandlung von erkrankungen des zentralnervensystems | |
| DE60223242D1 (de) | Substituierte amidderivate, deren zwischenprodukte, diese derivate enthaltendes insektizid für die verwendung in landwirtschaft und gartenbau und verfahren zu dessen verwendung | |
| MXPA05012358A (es) | Combinacion farmaceutica que comprende modafinilo y otra droga. | |
| DE60304695D1 (de) | 7-ARYLSULFONAMID-2,3,4,5-TETRAHYDRO-1H-BENZOiDöAZEPINE MIT 5-HT6 REZEPTOR AFFINITÄT ZUR BEHANDLUNG VON ZENTRALNERVENSYSTEMERKRANKUNGEN | |
| NO20055098D0 (no) | Anvendelse av 10-hydroksy-10,11-dihydrokarbamazepinderivater for behandling av affektive forstyrrelser | |
| DE60238717D1 (de) | Derivate und pharmazeutische zusammensetzungen von n-hydroxyalkyltetramethyl cyclo propan carboxamid mit antiepileptischer und verfahren zu deren herstellung | |
| DK1392676T3 (da) | Hidtil ukendte heterocykliske urinstofderivater og deres anvendelse som dopamin -D3 - receptorligander | |
| DE60228988D1 (de) | Monohyroxycarbamezepin zur verwendung bei der herstellung eines medikaments zur behandlung von affektiver psychose, aufmerksamkeits störungen und neuropathischen schmerzen | |
| IL164779A0 (en) | Substituted aminoalkanephosphonic acids for the treatment of neuropathic pain, affective and attention disorders, schizophrenia, tinnitus, myopia and other oculat disorders |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |