ATE493116T1 - Verfahren zur herstellung von mikroteilchen - Google Patents
Verfahren zur herstellung von mikroteilchenInfo
- Publication number
- ATE493116T1 ATE493116T1 AT05701939T AT05701939T ATE493116T1 AT E493116 T1 ATE493116 T1 AT E493116T1 AT 05701939 T AT05701939 T AT 05701939T AT 05701939 T AT05701939 T AT 05701939T AT E493116 T1 ATE493116 T1 AT E493116T1
- Authority
- AT
- Austria
- Prior art keywords
- microparticles
- solvent
- bioactive
- mixture
- dissolved
- Prior art date
Links
- 239000011859 microparticle Substances 0.000 title abstract 4
- 238000004519 manufacturing process Methods 0.000 title 1
- 239000002904 solvent Substances 0.000 abstract 4
- 230000000975 bioactive effect Effects 0.000 abstract 2
- 239000000839 emulsion Substances 0.000 abstract 2
- 238000000034 method Methods 0.000 abstract 2
- 239000000203 mixture Substances 0.000 abstract 2
- 238000004945 emulsification Methods 0.000 abstract 1
- 238000001704 evaporation Methods 0.000 abstract 1
- 239000004094 surface-active agent Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1635—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J13/00—Colloid chemistry, e.g. the production of colloidal materials or their solutions, not otherwise provided for; Making microcapsules or microballoons
- B01J13/02—Making microcapsules or microballoons
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1682—Processes
- A61K9/1694—Processes resulting in granules or microspheres of the matrix type containing more than 5% of excipient
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Dispersion Chemistry (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Medicinal Preparation (AREA)
- Manufacturing Of Micro-Capsules (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Compounds Of Unknown Constitution (AREA)
- Colloid Chemistry (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB0401291A GB0401291D0 (en) | 2004-01-21 | 2004-01-21 | Method of producing microparticles |
| GB0418141A GB0418141D0 (en) | 2004-08-13 | 2004-08-13 | Method of producing microparticles |
| PCT/GB2005/000174 WO2005070391A2 (en) | 2004-01-21 | 2005-01-19 | Method of producing microparticles |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE493116T1 true ATE493116T1 (de) | 2011-01-15 |
Family
ID=34809878
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT05701939T ATE493116T1 (de) | 2004-01-21 | 2005-01-19 | Verfahren zur herstellung von mikroteilchen |
Country Status (7)
| Country | Link |
|---|---|
| US (2) | US8343545B2 (de) |
| EP (1) | EP1722761B1 (de) |
| JP (1) | JP4961213B2 (de) |
| AT (1) | ATE493116T1 (de) |
| DE (1) | DE602005025606D1 (de) |
| DK (1) | DK1722761T3 (de) |
| WO (1) | WO2005070391A2 (de) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP4961213B2 (ja) * | 2004-01-21 | 2012-06-27 | ザ・スクール・オブ・ファーマシー | マイクロ粒子の製造方法 |
| DE102007009242A1 (de) * | 2007-02-22 | 2008-09-18 | Evonik Röhm Gmbh | Pellets mit magensaftresistenter Wirkstoff-Matix |
| GB201107629D0 (en) * | 2011-05-06 | 2011-06-22 | Proxima Concepts Ltd | Hydrophobic preparations |
| EP3634507B1 (de) * | 2017-06-07 | 2025-01-15 | EGY-Nano Pharma, LP | Orale, verlängerte wirkstofffreisetzungsplattformen |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4652641A (en) * | 1984-06-26 | 1987-03-24 | S. C. Mitri | Benzofused lactams useful as antihypertensive agents and as cholecystokinin antagonists |
| FR2618674B1 (fr) * | 1987-07-30 | 1990-06-15 | Ire Celltarg Sa | Microparticules comportant un polymere biodegradable controlant la liberation d'un principe actif antimalarique, compositions pharmaceutiques en comprenant et procede de preparation |
| JP2670680B2 (ja) * | 1988-02-24 | 1997-10-29 | 株式会社ビーエムジー | 生理活性物質含有ポリ乳酸系微小球およびその製造法 |
| JPH04190844A (ja) * | 1990-11-26 | 1992-07-09 | Nippon Kayaku Co Ltd | マイクロカプセルの製法 |
| US5824638A (en) * | 1995-05-22 | 1998-10-20 | Shire Laboratories, Inc. | Oral insulin delivery |
| NZ502500A (en) | 1997-06-27 | 2002-03-28 | Vivorx Pharmaceuticals Inc | Novel formulations of pharmacological agents, methods for the preparation thereof and methods for the use thereof |
| FR2769854B1 (fr) | 1997-10-21 | 2000-03-31 | Prographarm Lab | Nouveau procede d'obtention de microspheres et les produits ainsi realises |
| KR100289471B1 (ko) * | 1998-01-19 | 2001-09-17 | 김충섭 | 휀타닐계마취제의이식형서방성제제 |
| US6312712B1 (en) * | 1999-08-26 | 2001-11-06 | Robert R. Whittle | Method of improving bioavailability |
| US6303651B1 (en) * | 1999-09-23 | 2001-10-16 | Thione International, Inc. | Synergistic antioxidant veterinary compositions |
| US6623761B2 (en) * | 2000-12-22 | 2003-09-23 | Hassan Emadeldin M. | Method of making nanoparticles of substantially water insoluble materials |
| US6692771B2 (en) * | 2001-02-23 | 2004-02-17 | Cima Labs Inc. | Emulsions as solid dosage forms for oral administration |
| JP4961213B2 (ja) * | 2004-01-21 | 2012-06-27 | ザ・スクール・オブ・ファーマシー | マイクロ粒子の製造方法 |
-
2005
- 2005-01-19 JP JP2006550272A patent/JP4961213B2/ja not_active Expired - Fee Related
- 2005-01-19 DK DK05701939.0T patent/DK1722761T3/da active
- 2005-01-19 DE DE602005025606T patent/DE602005025606D1/de not_active Expired - Lifetime
- 2005-01-19 AT AT05701939T patent/ATE493116T1/de active
- 2005-01-19 EP EP05701939A patent/EP1722761B1/de not_active Expired - Lifetime
- 2005-01-19 WO PCT/GB2005/000174 patent/WO2005070391A2/en not_active Ceased
- 2005-01-19 US US10/597,328 patent/US8343545B2/en not_active Expired - Fee Related
-
2012
- 2012-12-05 US US13/705,928 patent/US20130101646A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| DK1722761T3 (da) | 2011-03-28 |
| JP2007518780A (ja) | 2007-07-12 |
| DE602005025606D1 (de) | 2011-02-10 |
| US20130101646A1 (en) | 2013-04-25 |
| US20080241251A1 (en) | 2008-10-02 |
| WO2005070391A2 (en) | 2005-08-04 |
| WO2005070391A3 (en) | 2005-09-09 |
| EP1722761A2 (de) | 2006-11-22 |
| JP4961213B2 (ja) | 2012-06-27 |
| EP1722761B1 (de) | 2010-12-29 |
| US8343545B2 (en) | 2013-01-01 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification |
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