ATE493116T1 - Verfahren zur herstellung von mikroteilchen - Google Patents

Verfahren zur herstellung von mikroteilchen

Info

Publication number
ATE493116T1
ATE493116T1 AT05701939T AT05701939T ATE493116T1 AT E493116 T1 ATE493116 T1 AT E493116T1 AT 05701939 T AT05701939 T AT 05701939T AT 05701939 T AT05701939 T AT 05701939T AT E493116 T1 ATE493116 T1 AT E493116T1
Authority
AT
Austria
Prior art keywords
microparticles
solvent
bioactive
mixture
dissolved
Prior art date
Application number
AT05701939T
Other languages
English (en)
Inventor
Abdul Waseh Basit
Richard Andrew Kendall
Sudax Shina Murdan
Original Assignee
Univ London Pharmacy
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB0401291A external-priority patent/GB0401291D0/en
Priority claimed from GB0418141A external-priority patent/GB0418141D0/en
Application filed by Univ London Pharmacy filed Critical Univ London Pharmacy
Application granted granted Critical
Publication of ATE493116T1 publication Critical patent/ATE493116T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1635—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J13/00—Colloid chemistry, e.g. the production of colloidal materials or their solutions, not otherwise provided for; Making microcapsules or microballoons
    • B01J13/02—Making microcapsules or microballoons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1682—Processes
    • A61K9/1694—Processes resulting in granules or microspheres of the matrix type containing more than 5% of excipient

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Dispersion Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Medicinal Preparation (AREA)
  • Manufacturing Of Micro-Capsules (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Compounds Of Unknown Constitution (AREA)
  • Colloid Chemistry (AREA)
AT05701939T 2004-01-21 2005-01-19 Verfahren zur herstellung von mikroteilchen ATE493116T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB0401291A GB0401291D0 (en) 2004-01-21 2004-01-21 Method of producing microparticles
GB0418141A GB0418141D0 (en) 2004-08-13 2004-08-13 Method of producing microparticles
PCT/GB2005/000174 WO2005070391A2 (en) 2004-01-21 2005-01-19 Method of producing microparticles

Publications (1)

Publication Number Publication Date
ATE493116T1 true ATE493116T1 (de) 2011-01-15

Family

ID=34809878

Family Applications (1)

Application Number Title Priority Date Filing Date
AT05701939T ATE493116T1 (de) 2004-01-21 2005-01-19 Verfahren zur herstellung von mikroteilchen

Country Status (7)

Country Link
US (2) US8343545B2 (de)
EP (1) EP1722761B1 (de)
JP (1) JP4961213B2 (de)
AT (1) ATE493116T1 (de)
DE (1) DE602005025606D1 (de)
DK (1) DK1722761T3 (de)
WO (1) WO2005070391A2 (de)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE602005025606D1 (de) * 2004-01-21 2011-02-10 Univ London Pharmacy Verfahren zur herstellung von mikroteilchen
DE102007009242A1 (de) * 2007-02-22 2008-09-18 Evonik Röhm Gmbh Pellets mit magensaftresistenter Wirkstoff-Matix
GB201107629D0 (en) * 2011-05-06 2011-06-22 Proxima Concepts Ltd Hydrophobic preparations
WO2018226383A1 (en) * 2017-06-07 2018-12-13 Egy-Nano Pharma, Lp Oral prolonged drug delivery platforms

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4652641A (en) * 1984-06-26 1987-03-24 S. C. Mitri Benzofused lactams useful as antihypertensive agents and as cholecystokinin antagonists
FR2618674B1 (fr) * 1987-07-30 1990-06-15 Ire Celltarg Sa Microparticules comportant un polymere biodegradable controlant la liberation d'un principe actif antimalarique, compositions pharmaceutiques en comprenant et procede de preparation
JP2670680B2 (ja) * 1988-02-24 1997-10-29 株式会社ビーエムジー 生理活性物質含有ポリ乳酸系微小球およびその製造法
JPH04190844A (ja) * 1990-11-26 1992-07-09 Nippon Kayaku Co Ltd マイクロカプセルの製法
US5824638A (en) * 1995-05-22 1998-10-20 Shire Laboratories, Inc. Oral insulin delivery
PT1023050E (pt) * 1997-06-27 2013-12-04 Abraxis Bioscience Llc Novas formulações de agentes farmacológicos, métodos para a sua preparação e métodos para a sua utilização
FR2769854B1 (fr) * 1997-10-21 2000-03-31 Prographarm Lab Nouveau procede d'obtention de microspheres et les produits ainsi realises
KR100289471B1 (ko) 1998-01-19 2001-09-17 김충섭 휀타닐계마취제의이식형서방성제제
US6312712B1 (en) * 1999-08-26 2001-11-06 Robert R. Whittle Method of improving bioavailability
US6303651B1 (en) * 1999-09-23 2001-10-16 Thione International, Inc. Synergistic antioxidant veterinary compositions
US6623761B2 (en) * 2000-12-22 2003-09-23 Hassan Emadeldin M. Method of making nanoparticles of substantially water insoluble materials
US6692771B2 (en) * 2001-02-23 2004-02-17 Cima Labs Inc. Emulsions as solid dosage forms for oral administration
DE602005025606D1 (de) * 2004-01-21 2011-02-10 Univ London Pharmacy Verfahren zur herstellung von mikroteilchen

Also Published As

Publication number Publication date
DE602005025606D1 (de) 2011-02-10
EP1722761A2 (de) 2006-11-22
EP1722761B1 (de) 2010-12-29
US20080241251A1 (en) 2008-10-02
JP2007518780A (ja) 2007-07-12
WO2005070391A3 (en) 2005-09-09
WO2005070391A2 (en) 2005-08-04
US8343545B2 (en) 2013-01-01
US20130101646A1 (en) 2013-04-25
DK1722761T3 (da) 2011-03-28
JP4961213B2 (ja) 2012-06-27

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